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11. 发明专利

JPH11501678A 失效
公开(公告)号：JPH11501678A
公开(公告)日：1999-02-09
申请号：JP53700297
申请日：1997-04-01
申请人： ASTRA AB
IPC分类号： A61K9/107 , A61K9/00 , A61K31/135 , A61K31/138 , A61K31/165 , A61K31/167 , A61K45/00 , A61K45/08 , A61K47/10 , A61K47/18 , A61K47/20 , A61K47/44 , A61P23/02 , A61P25/02 , A61K47/34

12. 发明专利

JPH06507629A 失效
公开(公告)号：JPH06507629A
公开(公告)日：1994-09-01
申请号：JP51057592
申请日：1992-05-14
申请人： ASTRA AB
发明人： BARTFAI TAMAS , HOEKFELT TOMAS , LANGEL ULO , AHREN BO , LINDSKOG STEFAN , CONSOLO SILVANA , LAND TIIT , WIESENFELD-HALLIN ZSUZSANNA
IPC分类号： A61K38/00 , A61K31/00 , A61K38/04 , A61K38/22 , A61P1/00 , A61P25/18 , A61P25/28 , C07K20060101 , C07K5/00 , C07K7/02 , C07K7/08 , C07K7/18 , C07K7/22 , C07K14/575 , C07K14/70 , A61K37/02 , A61K37/24 , A61K37/43 , C07K7/10

13. 发明申请

WO9602535A8 PROCESS FOR SYNTHESIS OF SUBSTITUTED SULPHOXIDES 审中-公开
标题翻译：用于合成取代的硫代氧化物的方法
公开(公告)号：WO9602535A8
公开(公告)日：1999-12-23
申请号：PCT/SE9500818
申请日：1995-07-03
申请人： ASTRA AB , LARSSON ERIK MAGNUS , STENHEDE URBAN JAN , SOERENSEN HENRIK , VON UNGE PER OSKAR SVERKER , COTTON HANNA KRISTINA
发明人： LARSSON ERIK MAGNUS , STENHEDE URBAN JAN , SOERENSEN HENRIK , VON UNGE PER OSKAR SVERKER , COTTON HANNA KRISTINA
IPC分类号： C07D401/12 , A61K31/415 , A61K31/4184 , A61P1/04 , A61P43/00 , B01J21/06 , B01J31/22 , C07B57/00 , C07B61/00 , C07D235/28 , C07D471/04
CPC分类号： C07D235/28 , C07D401/12
摘要： A novel process for enantioselective synthesis of single enantiomers of omeprazole or its alkaline salts, of other optically pure substituted 2-(2-pyridinylmethyl-sulphinyl)-1H-benzimidazoles as well as of other structurally related sulphoxides or their alkaline salts. The claimed process is an asymmetric oxidation of a pro-chiral sulphide to the single enantiomers or an enantiomerically enriched form of the corresponding sulphoxide. The application also claims the enantiomeric sulphoxide products produced by the process and their use in medicine.
摘要翻译：一种用于对映选择性合成奥美拉唑或其碱性盐，其它光学纯取代的2-（2-吡啶基甲基 - 亚磺酰基）-1H-苯并咪唑以及其它结构相关的亚砜或其碱性盐的单一对映异构体的新方法。要求保护的方法是将手性硫化物不对称地氧化成单一的对映异构体或相应的亚砜的对映体富集形式。本申请还要求通过该方法生产的对映异构体亚砜产物及其在药物中的用途。

14. 发明申请

WO2021156651A1 PHOTOVOLTAIC ELECTRICAL ENERGY GENERATION AND CONTROL SYSTEM AND METHOD OF ROAD TANKER FOR LIQUID OR GAS PRODUCTS METHOD THEREOF 审中-公开
公开(公告)号：WO2021156651A1
公开(公告)日：2021-08-12
申请号：PCT/IB2020/050898
申请日：2020-02-05
申请人： MACHINERY PLANT „ASTRA“ AB
发明人： LIESIONIS, Vaidas
IPC分类号： B60L8/00
摘要： The present invention solves the task of photovoltaic electrical energy generation on a road tanker surface and the control of generated photovoltaic electrical energy. It could be used for the electrical trucks or for trucks with internal combustion engines. The method has the following components: a truck, a road tanker, photovoltaic panels and an electrical system control mechanism. The photovoltaic panels generate photovoltaic electrical energy, which feeds the road tanker electrical users. The excess electrical energy is stored in the truck batteries, the road tanker batteries or both. Upon demand, the stored photovoltaic electrical energy is used to feed the road tanker electrical users, the truck driving electrical motor or the truck electrical equipment. The electrical system control mechanism ensures the safe regime of the photovoltaic electrical system.

15. 发明申请

WO9955706A9 IMIDAZO PYRIDINE DERIVATIVES WHICH INHIBIT GASTRIC ACID SECRETION 审中-公开
标题翻译：抑制胃酸分泌的咪唑吡啶衍生物
公开(公告)号：WO9955706A9
公开(公告)日：2000-03-16
申请号：PCT/SE9900663
申请日：1999-04-23
申请人： ASTRA AB , AMIN KOSRAT , DAHLSTROEM MICHAEL , NORDBERG PETER , STARKE INGEMAR
发明人： AMIN KOSRAT , DAHLSTROEM MICHAEL , NORDBERG PETER , STARKE INGEMAR
IPC分类号： C07D471/04 , A61K31/435 , A61K31/437 , A61K31/496 , A61K31/5355 , A61P1/00 , A61P1/04
CPC分类号： C07D471/04
摘要： The present invention relates to imidazo pyridine derivatives of formula (I), in which the phenyl moiety is substituted, and in which the imidazo pyridine moiety is substituted with a carboxyamide group in 6-position, which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.
摘要翻译：本发明涉及式（I）的咪唑并吡啶衍生物，其中苯基部分被取代，其中咪唑并吡啶部分被6位的羧酰胺基取代，其抑制外源或内源性刺激的胃酸分泌，因此可用于预防和治疗胃肠道炎症性疾病。

16. 发明申请

WO9932519A9 NOVEL G PROTEIN-COUPLED RECEPTOR 审中-公开
标题翻译：新型G蛋白偶联受体
公开(公告)号：WO9932519A9
公开(公告)日：1999-09-30
申请号：PCT/SE9802348
申请日：1998-12-16
申请人： ASTRA PHARMA INC , ASTRA AB , AHMAD SULTAN , BANVILLE DENIS , FORTIN YVES , LEMBO PAOLA , DONELL DAJAN O , SHEN SHI HSIANG
发明人： AHMAD SULTAN , BANVILLE DENIS , FORTIN YVES , LEMBO PAOLA , O'DONELL DAJAN , SHEN SHI-HSIANG
IPC分类号： G01N33/50 , C07K14/705 , C07K14/72 , C07K16/28 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , G01N33/15 , G01N33/566
CPC分类号： C07K14/705
摘要： The present invention is directed to novel G protein-coupled receptors that are found predominantly in the dorsal root ganglia. The invention encompasses both receptor proteins as well as nucleic acids encoding the proteins. Angiotension I and III effects Calcium signalling in Cells transformed with DNA encoding the receptor. In addition, the present invention is directed to methods and compositions which utilize the receptors.
摘要翻译：本发明涉及主要存在于背根神经节中的新型G蛋白偶联受体。本发明包括受体蛋白质和编码蛋白质的核酸。血管紧张素I和III影响用编码受体的DNA转化的细胞中的钙信号传导。另外，本发明涉及利用这些受体的方法和组合物。

17. 发明申请

WO9854171A8 NOVEL FORM OF S-OMEPRAZOLE 审中-公开
标题翻译： S-奥美拉唑的新形式
公开(公告)号：WO9854171A8
公开(公告)日：1999-12-23
申请号：PCT/SE9800974
申请日：1998-05-25
申请人： ASTRA AB , COTTON HANNA , KRONSTROEM ANDERS , MATTSON ANDERS , MOELLER EVA
发明人： COTTON HANNA , KRONSTROEM ANDERS , MATTSON ANDERS , MOELLER EVA
IPC分类号： A61K20060101 , A61K31/00 , A61K31/44 , A61K31/4439 , A61P20060101 , A61P1/04 , C07D20060101 , C07D401/12
CPC分类号： C07D401/12
摘要： The present invention relates to a novel form of the (-)-enantiomer of 5-methoxy-2- [[(4-methoxy-3,5-dimethyl-2-pyridinyl)- methyl]sulfinyl]-1 H -benzimidazole, i.e S-omeprazole. More specifically, it relates to a novel form of the magnesium salt of the S-enantiomer of omeprazole trihydrate. The present invention also relates to processes for preparing such a form of the magnesium salt of S-omeprazole and pharmaceutical compositions containing it. Furthermore, the present invention also relates to new intermediates used in the process.
摘要翻译：本发明涉及5-甲氧基-2 - [[（4-甲氧基-3,5-二甲基-2-吡啶基） - 甲基]亚磺酰基] -1H的（ - ） - 对映异构体的新形式苯并咪唑，即S-奥美拉唑。更具体地说，它涉及奥美拉唑三水合物的S-对映异构体的镁盐的新形式。本发明还涉及制备这种形式的S-奥美拉唑镁盐的方法和含有它的药物组合物。此外，本发明还涉及在该方法中使用的新的中间体。

18. 发明申请

WO9601622A8 NEW ORAL PHARMACEUTICAL FORMULATION CONTAINING MAGNESIUM SALT OF OMEPRAZOLE 审中-公开
标题翻译：含奥美拉唑镁盐的新口服药物制剂
公开(公告)号：WO9601622A8
公开(公告)日：1999-12-23
申请号：PCT/SE9500816
申请日：1995-07-03
申请人： ASTRA AB , BENGTSSON SIV INGA , LOEVGREN KURT INGMAR
发明人： BENGTSSON SIV INGA , LOEVGREN KURT INGMAR
IPC分类号： A61K20060101 , A61K9/24 , A61K9/28 , A61K9/30 , A61K9/50 , A61K9/52 , A61K31/44 , A61K31/4439 , A61P1/04
CPC分类号： A61K31/4439 , A61K9/2846 , A61K9/5026 , A61K9/5078
摘要： A new oral pharmaceutical formulation containing a novel physical form of a magnesium salt of omeprazole coated with one or more enteric coating layers, a method for the manufacture of such a formulation, the use of such a formulation in medicine and a blister package containing the new formulation.
摘要翻译：一种新的口服药物制剂，其含有涂覆有一种或多种肠溶衣层的奥美拉唑镁盐的新物理形式，制备这种制剂的方法，在医药中使用这种制剂以及含有新的公式。

19. 发明申请

WO9950953A3 AN AMPLIFICATION CIRCUIT AND AN OSCILLATOR COMPRISING SAID CIRCUIT 审中-公开
标题翻译：放大电路和包含电路的振荡器
公开(公告)号：WO9950953A3
公开(公告)日：1999-11-18
申请号：PCT/SE9900535
申请日：1999-03-30
申请人： ASTRA AB , MARNFELDT GOERAN
发明人： MARNFELDT GOERAN
IPC分类号： H03F3/30 , H03F3/45 , H03B5/00
CPC分类号： H03F3/3001 , H03F3/45076
摘要： The invention relates to an amplification circuit, comprising: a differential amplifier (241) having a first input node (236) and a second input node (240) for receiving respectively first and second input signals and an output node for producing an output signal; and active bias circuitry (250) connected to said differential amplifier (241) for drawing a bias current therefrom, wherein said active bias circuitry (250) is configured to draw an increased current when said first and second input signals are substantially equal. An oscillator comprising said amplification circuit and a circuit comprising an oscillator of said type is also part of the invention.
摘要翻译：本发明涉及一种放大电路，包括：差分放大器（241），具有用于分别接收第一和第二输入信号的第一输入节点（236）和第二输入节点（240）和用于产生输出信号的输出节点; 以及与所述差分放大器（241）连接以从其中抽出偏置电流的有源偏置电路（250），其中所述有源偏置电路（250）被配置为当所述第一和第二输入信号基本相等时绘制增加的电流。包括所述放大电路和包括所述类型的振荡器的电路的振荡器也是本发明的一部分。

20. 发明申请

WO9908500A2 NEW CRYSTALLINE FORM OF OMEPRAZOLE 审中-公开
标题翻译： OMEPRAZOLE的新型结晶形式
公开(公告)号：WO9908500A2
公开(公告)日：1999-02-25
申请号：PCT/SE9802028
申请日：1998-11-10
申请人： ASTRA AB , LOEVQVIST KARIN , NORELAND DAVID , SUNDEN GUNNEL , YMEN INGVAR
发明人： LOEVQVIST KARIN , NORELAND DAVID , SUNDEN GUNNEL , YMEN INGVAR
IPC分类号： C07D401/12 , A61K20060101 , A61K9/28 , A61K31/44 , A61K31/4427 , A61K31/4439 , A61K31/454 , A61P1/00 , A61P1/04 , C07D20060101 , C07D235/28
CPC分类号： C07D401/12 , A61K31/4439 , A61K31/454
摘要： The present invention relates to a novel crystalline form of 5-methoxy-2-[ [(4-methoxy-3,5-dimethyl- 2-pyridinyl)methyl] sulfinyl]-1 H - benzimidazole, know under the generic name omeprazole. Further, the present invention also relates to the use of the novel crystalline form of 5-methoxy-2-[ [(4-methoxy-3,5-dimethyl- 2-pyridinyl)methyl] sulfinyl]-1 H - benzimidazole for the treatment of gastrointestinal disorders, pharmaceutical compositions containing it as well as processes for the preparation of the novel crystalline form of 5-methoxy-2-[ [(4-methoxy-3,5-dimethyl- 2-pyridinyl)methyl] sulfinyl]-1 H - benzimidazole.
摘要翻译：本发明涉及5-甲氧基-2 - [[（4-甲氧基-3,5-二甲基-2-吡啶基）甲基]亚磺酰基] -1H-苯并咪唑的新型结晶形式，知道通用名奥美拉唑。此外，本发明还涉及5-甲氧基-2 - [[（4-甲氧基-3,5-二甲基-2-吡啶基）甲基]亚磺酰基] -1H的新结晶形式的用途，苯并咪唑，用于治疗胃肠道疾病，含有它的药物组合物以及制备5-甲氧基-2 - [[（4-甲氧基-3,5-二甲基-2- 吡啶基）甲基]亚磺酰基] -1H-苯并咪唑。

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