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    • 152. 发明授权
    • Space-filling intragastric implants with fluid flow
    • 填充胃内植入物与流体流动
    • US09095405B2
    • 2015-08-04
    • US13275211
    • 2011-10-17
    • Mitchell H. BabkesZachary DominguezJustin Schwab
    • Mitchell H. BabkesZachary DominguezJustin Schwab
    • A61F5/00
    • A61F5/0033A61F5/0003A61F5/0013A61F5/003A61F5/0036A61F5/0079A61F5/0086
    • A variety of passive intragastric implant devices for obesity treatment are disclosed. Such passive devices do not autonomously change shape, but instead react within the stomach to induce satiety. The devices may take up volume within the stomach, thus reducing the intake capacity. Additionally, the devices may contact areas within the stomach, such as the cardia surrounding the esophageal sphincter, to stimulate satiety-inducing nerves. Also, certain devices slow gastric emptying by blocking or otherwise impeding flow through the pyloric sphincter. A number of devices combine two or more of these satiety-inducing features. Methods of implant are disclosed including compressing the devices within a delivery tube and transorally advancing the devices through the esophagus to be deployed within the stomach. Removal of the devices occurs in the reverse.
    • 公开了用于肥胖症治疗的各种被动胃内植入装置。 这种被动装置不会自主地改变形状,而是在胃内反应以引起饱腹感。 这些装置可能占据胃内的体积,从而降低进气能力。 此外,装置可以接触胃内的区域,例如围绕食管括约肌的贲门,以刺激饱腹引起的神经。 此外,某些装置通过阻塞或阻碍通过幽门括约肌的流动来缓慢胃排空。 许多装置组合了这些饱腹感特征中的两种或更多种。 公开了植入物的方法,包括压缩输送管内的装置并且经由食道经过胃内部署的装置经过前进。 相反的移除设备。
    • 154. 发明申请
    • Reactive Intragastric Implant Devices
    • 反应性内植入装置
    • US20150150700A1
    • 2015-06-04
    • US14621094
    • 2015-02-12
    • Apollo Endosurgery, Inc.
    • Zachary DominguezJustin SchwabMitchell H. Babkes
    • A61F5/00
    • A61F5/0033A61F5/0036
    • Transoral implantable devices includes an inflatable body made of a material that permits it to be compressed into a substantially linear transoral delivery configuration and that when implanted in the stomach is adapted to reduce obesity or weight by stimulating the stomach walls of the patient. The body has a plurality of popout features on its surface that reside generally flush with the inflatable body in relaxed, refracted states, and which respond to an increase in pressure within the inflatable body by projecting outward from the body in a stressed, deployed state. The popout features may convert between their retracted and deployed states by movement of rolling diaphragms formed in the inflatable body.
    • 经口植入式装置包括由材料制成的可膨胀体,其允许其被压缩成基本上线性的经腹输送构型,并且当植入在胃中时,可以通过刺激患者的胃壁来减少肥胖或体重。 主体在其表面上具有多个突出特征,其大体上以可松弛的折射状态与可膨胀的身体平齐,并且通过在受压的展开状态从身体向外突出而响应于可充气体内的压力的增加。 弹出功能可以通过形成在可充气体中的滚动隔膜的移动而在其缩回状态和展开状态之间转换。
    • 157. 发明申请
    • STOMACH PERISTALSIS DEVICE AND METHOD
    • STOMACH PERISTALSIS设备和方法
    • US20140135944A1
    • 2014-05-15
    • US14043026
    • 2013-10-01
    • InCube Labs, LLC
    • Mir Imran
    • A61F2/04
    • A61F2/04A61F5/003A61F5/0033A61F5/0053A61F5/0079A61F2002/045A61F2002/482A61F2250/0003
    • The invention relates to an implantable stomach prosthesis for surgically replacing or augmenting all or part of the antrum and/or pylorus of a stomach. The prosthesis controls the passage of food from the stomach to the small intestine. The prosthesis may be configured to churn ingested material and release it from the stomach through a prosthetic pyloric valve. At least one expandable member is arranged to be expanded to control the passage of food and/or to mimic the churning action of a patient's stomach. The prosthesis includes an outer support structure, a flexible inner member forming a conduit for the movement of material, and at least one expandable member located between the outer support structure and inner member. An implantable pump system is provided for inflating and deflating the expandable member(s).
    • 本发明涉及一种用于手术替换或增加胃的全部或部分胃窦和/或幽门的可植入胃假体。 假体控制食物从胃到小肠的通过。 假体可以构造成搅动摄取的材料并通过假肢幽门阀将其从胃释放。 至少一个可膨胀构件被布置成扩张以控制食物的通过和/或模拟患者胃的搅动作用。 假体包括外部支撑结构,形成用于材料运动的导管的柔性内部构件以及位于外部支撑结构和内部构件之间的至少一个可扩张构件。 提供可植入泵系统用于使可膨胀构件膨胀和放气。
    • 158. 发明申请
    • STOMACH-SPANNING GASTRIC IMPLANTS
    • US20130289466A1
    • 2013-10-31
    • US13931561
    • 2013-06-28
    • Allergan, Inc.
    • Mitchell H. BabkesZachary Dominguez
    • A61F5/00
    • A61F5/0036A61F5/0003A61F5/0013A61F5/003A61F5/0033A61F5/0073A61F5/0076A61F5/0079A61F5/0086A61F5/0089Y10T24/44342Y10T24/4453Y10T24/44564
    • A variety of passive intragastric implant devices for obesity treatment are disclosed. Such passive implants do not autonomously change shape, but instead react within the stomach to induce satiety. The implants may take up volume within the stomach, thus reducing the digestive capacity. Additionally, the implants may contact areas within the stomach, such as the cardia surrounding the esophageal sphincter, to stimulate satiety-inducing nerves. Also, a number of implants slow gastric emptying by blocking or otherwise impeding flow through the pyloric sphincter. Other implants delay digestion by providing a duodenal sleeve. A number of implants combine two or more of these satiety-inducing features. Methods of implant are disclosed including compressing the implants within a delivery tube and transorally advancing the implants through the esophagus to be deployed within the stomach. Removal of the implants occurs in the reverse.
    • 公开了用于肥胖症治疗的各种被动胃内植入装置。 这种被动植入物不会自主地改变形状,而是在胃内反应以引起饱腹感。 植入物可能占据胃内的体积,从而降低消化能力。 此外,植入物可以接触胃内的区域,例如食道括约肌周围的贲门,以刺激饱腹引起的神经。 此外,许多种植体通过阻塞或以其他方式妨碍通过幽门括约肌的流动来缓慢胃排空。 其他植入物通过提供十二指肠套管延迟消化。 许多植入物结合了这些饱腹感诱发特征中的两种或更多种。 公开了植入物的方法,包括压缩输送管内的植入物并将植入体经过食道经过胃内部署的食管。 相反的移植植入物。