会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 146. 发明公开
    • Acyloxypropanolamines
    • Acyloxypropanolamine。
    • EP0373593A2
    • 1990-06-20
    • EP89122923.9
    • 1989-12-12
    • THE DU PONT MERCK PHARMACEUTICAL COMPANY
    • Patil, GhanshyamMai, Khuong H.X.
    • C07C233/18A61K31/16C07D295/20A61K31/535C07D307/24A61K31/34C07C219/06C07C219/12A61K31/215
    • C07D295/215C07C219/06C07C219/12C07C233/18C07C2601/00C07D307/24
    • Compounds of the present invention, are represented by the general formula
      wherein R represents a straight or branched loweralkyl from 1 to about 6 carbon atoms, loweralkene from 2 to about 6 carbon atoms, or
      where m is o or 1 and n is 2, 3, 4 or 5 provided that when m is o, n is 2, 3, 4, or 5 and when m is 1, n is 3 or 4, and R 1 is hydrogen, a straight, branched or cyclic loweralkyl from 1 to about 6 carbon atoms or loweralkoxy, phenyl or substituted phenyl, and R 2 represents a straight or branched loweralkyl from 1 to about 6 carbon atoms or W-B wherein W represents alkylene of from 1 to about 10 carbon atoms which may be substituted with loweralkyl of from 1 to about 4 carbon atoms; and B represents hydrogen, -NHCOR 4 , or -NHCONR 3 R 4 , wherein R 3 and R 4 may be the same or different and may be hydrogen, alkyl, alkoxyalkyl, cycloalkyl, alkenyl, alkynyl, phenyl or aralkyl wherein the alkyl group contains from 1 to about 6 carbon atoms and the aryl group represents phenyl which may be unsubstituted or substituted with lower alkyl from 1 to about 6 carbon atoms, alkoxy wherein the alkyl group contains from 1 to about 6 carbon atoms, halogen, acetamido, amino, hydroxy, hydroxyalkyl of from 1 to about 10 carbon atoms; thiophenyl, imidazole, oxazole or indole, furanyl, tetrahydrofuranyl or R 3 and R4 may together with N form a pyrrolidino, piperidino, piperazino, or morpholino ring, or a pharmaceutically acceptable salt thereof. The compounds are useful in the treatment or prophylaxis of cardiac disorder or in the treatment of glaucoma.