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131. 发明专利

MX2008016011A FRAGMENTOS DE PEPTIDOS PARA INDUCIR SINTESIS DE PROTEINAS DE MATRIZ EXTRA-CELULAR. 未知
公开(公告)号：MX2008016011A
公开(公告)日：2009-02-13
申请号：MX2008016011
申请日：2007-06-12
申请人： HELIX BIOMEDIX INC
发明人： HARRIS SCOTT M , TIMOTHY J FALLA , ZHANG LIJUAN
IPC分类号： C07K14/78 , C07K5/10
摘要： Tetra-péptidos biológicamente activos cortos se divulgan que están comprendidos de las secuencias GxxG y PxxP donde G (glicina) y P (prolina) se mantienen y x es un aminoácido variable. Los péptidos pueden usarse solos o en combinación para estimular la producción de proteínas de matriz extra-celular en piel. Un método de bajo costo rápido, para producir formulaciones heterogéneas de tetra-péptidos se divulga.

132. 发明专利

AU2007342353A1 Short bio-active peptides for cellular and immunological modulation 未知
公开(公告)号：AU2007342353A1
公开(公告)日：2008-07-17
申请号：AU2007342353
申请日：2007-12-27
申请人： HELIX BIOMEDIX INC
发明人： ZHANG LIJUAN , HARRIS SCOTT M , FALLA TIMOTHY J
IPC分类号： C07K14/435 , A61K38/00
摘要： Peptides having four to fourteen residues are disclosed that possess biological activity. These peptides constitute short fragments of the peptide HB-107 (SEQ ID NO:1), which itself is a fragment of the antimicrobial protein cecropin B, and exhibit cell stimulatory, migratory and anti-inflammatory properties. As keratinocytes are especially sensitive to these effects, the disclosed peptides comprise a useful agent for the medical treatment of injury to the skin, such as from diabetic ulcers. The peptides also are effective in preventing and reversing skin surface damage resulting from various environmental insults. Importantly, the therapeutic effects of the peptides manifest at concentrations equal to or greater than those of peptide HB-107, and thus represent a less expensive, more versatile means for developing effective therapies. Methods for the production and use of these peptides are also disclosed.

133. 发明申请

WO03091973A8 IMAGE DISPLAY DEVICE WITH MICROLIGHT SOURCES AND SOFT LIGHT PANEL 审中-公开
标题翻译：具有微光源和软光板的图像显示装置
公开(公告)号：WO03091973A8
公开(公告)日：2005-01-27
申请号：PCT/CN0300280
申请日：2003-04-17
申请人： YANG ZHONGYI , ZHANG LIJUAN , YANG SHUAIBING , ZHANG YANGJING
发明人： YANG ZHONGYI , ZHANG LIJUAN , YANG SHUAIBING , ZHANG YANGJING
IPC分类号： F21V8/00 , G02B6/00 , G09F13/18
CPC分类号： G02B6/006 , G02B6/0021 , G02B6/0036 , Y10S362/812
摘要： An image display device with microlight sources and soft light panel includes light sources and a transparent panel. The said light sources are inlayed in the grooves of the edges of the said panel. The said images to be displayed are mounted on the surface of the panel or formed by the concavo-convex parts inside or outside the surface. With the illumination of the micro power light sources, the device gives a soft light indirectly through the reflection or refraction of the light and can be used for longcontinued illumination indoors or outdoors or in dark conditions. The images that the device gives look clear and have strong stereo feelings and various changes. The device has lower costs and longer life and can be particularly used as safe and fire-fighting image signs in dark places such as cinemas, underpasses etc. Also it can be used for illumination.
摘要翻译：具有微光源和柔光灯的图像显示装置包括光源和透明面板。所述光源被嵌入所述面板的边缘的凹槽中。要显示的所述图像被安装在面板的表面上或者由表面内部或外部的凹凸部分形成。通过微功率光源的照明，该装置通过光的反射或折射间接地产生柔和的光，并可用于室内或室外或黑暗条件下的长时间照明。设备给出的图像看起来很清晰，具有强烈的立体感和各种变化。该设备具有较低的成本和更长的使用寿命，可以特别用作电影院，地下通道等暗处的安全防火图像标志。此外，它还可用于照明。

134. 发明申请

WO9922005B1 HEPARAN SULFATE D-GLUCOSAMINYL 3-O-SULFOTRANSFERASES, AN USES THEREFOR 审中-公开
标题翻译：硫酸乙酰肝素D-葡糖胺3-O-磺酸酯转运酶，用途
公开(公告)号：WO9922005B1
公开(公告)日：1999-11-11
申请号：PCT/US9822597
申请日：1998-10-23
申请人： MASSACHUSETTS INST TECHNOLOGY , ROSENBERG ROBERT D , SHWORAK NICHOLAS W , LIU JIAN , FRITZE LINDA M S , SCHWARTZ JOHN J , ZHANG LIJUAN
发明人： ROSENBERG ROBERT D , SHWORAK NICHOLAS W , LIU JIAN , FRITZE LINDA M S , SCHWARTZ JOHN J , ZHANG LIJUAN
IPC分类号： C12N9/10 , C12N15/54 , A01K67/027 , C07K16/40 , G01N33/68
CPC分类号： C12N9/13 , A01K2217/05 , C07K2319/20
摘要： Disclosed are novel isolated nucleic acids and substancially pure protein preparations for naturally occurring and synthetic or chimeric heparan sulfate D-glucosaminyl 3-O-sulfo-transferases (3-OSTs). Also disclosed are uses for these genes and proteins, including uses for the modification and sequencing of glycosaminoglycans.
摘要翻译：公开了用于天然存在的和合成的或嵌合的硫酸乙酰肝素D-葡糖胺基3-O-磺基转移酶（3-OST）的新型分离的核酸和基本纯的蛋白质制剂。还公开了这些基因和蛋白质的用途，包括用于糖胺聚糖的修饰和测序。

135. 发明申请

WO9922005A3 HEPARAN SULFATE D-GLUCOSAMINYL 3-O-SULFOTRANSFERASES, AN USES THEREFOR 审中-公开
公开(公告)号：WO9922005A3
公开(公告)日：1999-10-07
申请号：PCT/US9822597
申请日：1998-10-23
申请人： MASSACHUSETTS INST TECHNOLOGY , ROSENBERG ROBERT D , SHWORAK NICHOLAS W , LIU JIAN , FRITZE LINDA M S , SCHWARTZ JOHN J , ZHANG LIJUAN
发明人： ROSENBERG ROBERT D , SHWORAK NICHOLAS W , LIU JIAN , FRITZE LINDA M S , SCHWARTZ JOHN J , ZHANG LIJUAN
IPC分类号： C12N9/10 , C12N15/54 , A01K67/027 , C07K16/40 , G01N33/68
CPC分类号： C12N9/13 , A01K2217/05 , C07K2319/20
摘要： Disclosed are novel isolated nucleic acids and substancially pure protein preparations for naturally occurring and synthetic or chimeric heparan sulfate D-glucosaminyl 3-O-sulfo-transferases (3-OSTs). Also disclosed are uses for these genes and proteins, including uses for the modification and sequencing of glycosaminoglycans.

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