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    • 121. 发明授权
    • Immunochromatographic assay device
    • 免疫色谱测定装置
    • US06605476B2
    • 2003-08-12
    • US09308154
    • 1999-11-01
    • Eiji Kobayashi
    • Eiji Kobayashi
    • G01N33558
    • G01N33/54366Y10S435/805Y10S435/81Y10S435/97Y10S436/809Y10S436/81
    • A chromatography immunoassay device is described which can be used more easily, is protected from moisture and/or oxygen more effectively and can be produced at a lower cost than known chromatography immunoassay devices. The chromatography immunoassay device of the present invention is one in which one or more chromatography strips are stuck on a substrate made of a plate, each of the chromatography strips is sealed by closely adhering a substrate portion surrounding each chromatography strip to a seal film located on the chromatography strip, and the seal film and/or substrate possesses a film containing a dehumidifying agent and/or a film containing an oxygen absorbing agent.
    • 描述了可以更容易地使用的色谱免疫测定装置,更有效地防止湿气和/或氧气,并且可以以比已知的色谱免疫测定装置更低的成本生产。 本发明的色谱免疫测定装置是将一个或多个色谱条粘贴在由板制成的基板上的每个色谱条,通过将围绕每个色谱条的基板部分紧密粘附到位于 色谱条和密封膜和/或基底具有含有除湿剂和/或含氧吸收剂的膜的膜。
    • 123. 发明授权
    • 5-membered ring compounds
    • 5元环化合物
    • US06380262B1
    • 2002-04-30
    • US09762265
    • 2001-02-06
    • Eiji KobayashiHiromu OhnogiNobuto KoyamaKatsushige IkaiHiroaki SagawaIkunoshin Kato
    • Eiji KobayashiHiromu OhnogiNobuto KoyamaKatsushige IkaiHiroaki SagawaIkunoshin Kato
    • A61K3112
    • C07K5/0215A61K38/00
    • 5-Membered ring compounds represented by general formula (I), optically active isomers thereof or salts of the same. These compounds have physiological activities including a carcinostatic effect. In said formula the bond shown by the dotted line in the 5-membered ring represents that this 5-membered ring may be either a cyclopentene ring having a double bond or a saturated cyclopentane ring, and when the 5-membered ring is a cyclopentene ring, X is OR1, Y is ═O and Z is H, and when it is a cyclopentane ring, X is ═O, Y is OR2 and Z is OR3, (wherein R1 is R4 or —(CO)—R5; R2 is H, —R6 or —(CO)—R7; and R3 is H, R8 or (CO)—R9 (wherein R4, R5, R6, R7, R8 and R9 are the same or different and each represents an aliphatic, aromatic or aliphatic aromatic group, and R5, R7 and R9 may be each H), provided that the case where R2═R3═H is excluded); and W represents a residue obtained by eliminating SH from an SH-containing compound.
    • 由通式(I)表示的5-元环化合物,其旋光异构体或其盐。 这些化合物具有包括致癌作用的生理活性。 在所述式中,五元环中虚线所示的键表示该5元环可以是具有双键或饱和环戊烷环的环戊烯环,当5元环为环戊烯环时 X为OR 1,Y为= O且Z为H,当为环戊烷环时,X为= O,Y为OR 2,Z为OR 3,(其中R1为R4或 - (CO)-R5; R2为 H,-R6或 - (CO)-R7; R3为H,R8或(CO)-R9(其中R4,R5,R6,R7,R8和R9相同或不同,各自表示脂族,芳族或 脂族芳族基团,R 5,R 7和R 9可以各自为H),条件是排除R2 = R3 = H的情况); W表示通过从含SH化合物中除去SH而得到的残基。