专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

121. 发明专利

MA27848A1 FORMES POSOLOGIQUES D'AZITHROMYCINE A EFFETS SECONDAIRES REDUITS. 未知
公开(公告)号：MA27848A1
公开(公告)日：2006-04-03
申请号：MA28638
申请日：2005-12-08
申请人： PFIZER PROD INC
发明人： THOMBRE AVINASH GOVIND , APPEL LEAH ELIZABETH , CREW MARSHALL DAVID , FRIESEN DWAYNE THOMAS , LYON DAVID KEITH , MCCRAY SCOTT BALDWIN , WEST JAMES BLAIR , HERBIG SCOTT MAX , LO JULIAN BELKNAP , HAGEN TIMOTHY ARTHUR
IPC分类号： C07H17/00 , A61K9/00 , A61K9/16 , A61K9/20 , A61K31/7052 , A61K47/02 , A61K47/14 , A61K47/18 , A61K47/44 , A61P31/04
摘要： DEPOSANT Société dite : PFIZER PRODUCTS INC. REVENDICATION DE PRIORITES US 4 Décembre 2003 60/527,084 US 23 Janvier 2004 10/763,340 Voir en annexe le titre de l'invention et le texte de l'abrégé Formes posologiques d'azithromycine à effets secondaires réduits Une forme posologique orale comprenant de l??azithromycine et une quantité efficace d'un agent alcalinisant. De préférence, ladite forme posologique orale comprend une quantité efficace d'un agent alcalinisant et une forme en particules multiples d1azithromycine, ladite forme en particules multiples comprenant de l??azithromycine, un mélange de monobéhénate de glycéryle, de dibéhénate de glycéryle et de tribéhénate de glycéryle, et un poloxamère. Habituellement, la forme posologique orale comprend n'importe quel moyen d'administration orale convenable tel qu'une poudre pour suspension orale, un paquet ou sachet de dose unitaire, un comprimé ou une capsule. Il est révélé en outre une suspension orale comprenant de l'azithromycine, une quantité efficace d'un agent alcalinisant et un véhicule. De préférence, l??azithromycine est une forme en particules multiples dans laquelle lesdites particules multiples comprennent de l'azithro-mycine, un mélange de monobéhénate de glycéryle, de dibéhénate de glycéryle et de tribéhénate de glycéryle, et un poloxamère. Il est révélé également une méthode pour réduire les effets secondaires gastro-intestinaux, associés à l'administration d1azithromycine à un mammifère, comprenant l'administration de manière contigue d'azithromycine et d'une quantité efficace d'un agent alcalinisant audit mammifère, la fréquence des effets secondaires gastro-intestinaux étant inférieure à celle constatée en administrant une dose égale d'azithromycine sans ledit agent alcalinisant. Il est révélé en outre une méthode pour le traitement d'une infection par des bactéries ou des protozoaires chez un mammifère nécessitant un tel traitement, comprenant l'administration de manière contigue audit mammifère d'une dose unique d'une forme posologique orale, ladite forme posologique orale comprenant del??azithromycine et une quantité efficace d'un agent alcalinisant. Il est révélé en outre une forme en particules multiples d'azithromycine comprenant del??azithromycine, un agent tensio-actif et un support pharmaceutiquement acceptable.

122. 发明专利

CA2578474A1 CONTROLLED RELEASE DOSAGE FORMS COMBINING IMMEDIATE RELEASE AND SUSTAINED RELEASE OF LOW-SOLUBILITY DRUG 未知
公开(公告)号：CA2578474A1
公开(公告)日：2006-03-09
申请号：CA2578474
申请日：2005-08-19
申请人： PFIZER PROD INC
发明人： FRIESEN DWAYNE THOMAS , APPEL LEAH ELIZABETH , THOMBRE AVINASH GOVIND , HERBIG SCOTT MAX
IPC分类号： A61K9/20 , A61K9/50 , A61K31/496

123. 发明专利

HRP20040865A2 AZITHROMYCIN DOSAGE FORMS WITH REDUCED SIDE EFFECTS 未知
公开(公告)号：HRP20040865A2
公开(公告)日：2006-02-28
申请号：HRP20040865
申请日：2004-09-20
申请人： PFIZER PROD INC
发明人： HAGEN TIMOTHY ARTHUR , HERBIG SCOTT MAX , LO JULIAN BELKNAP , THOMBRE AVINASH GOVIND , APPEL LEAH ELIZABETH , CREW MARSHALL DAVID , FRIESEN DWAYNE THOMAS , LYON DAVID KEITH , MCCRAY SCOTT BALDWIN , WEST JAMES BLAIR
IPC分类号： A61K9/16 , C07H17/00 , A61K9/00 , A61K9/20 , A61K31/7052 , A61K47/02 , A61K47/14 , A61K47/18 , A61K47/44 , A61P31/04
摘要： An oral dosage form comprising azithromycin and an effective amount of an alkalizing agent. Preferably, said oral dosage form comprises an effective amount of an alkalizing agent and an azithromycin multiparticulate wherein said multiparticulate comprises azithromycin, a mixture of glyceryl monobehenate, glyceryl dibehenate and glyceryl tribehenate, and a poloxamer. Typically, the oral dosage form includes any suitable oral dosing means such as a powder for oral suspension, a unit dose packet or sachet, a tablet or a capsule. Additionally disclosed is an oral suspension comprising azithromycin, an effective amount of an alkalizing agent and a vehicle. Preferably, the azithromycin is in multiparticulate form wherein said multiparticulate comprises azithromycin, a mixture of glyceryl monobehenate, glyceryl dibehenate and glyceryl tribehenate, and a poloxamer. Also disclosed is a method for reducing gastrointestinal side effects, associated with administering azithromycin to a mammal, comprising contiguously administering azithromycin and an effective amount of alkalizing agent to said mammal wherein the frequency of gastrointestinal side effects is lower than that experienced by administering an equal dose of azithromycin without said alkalizing agent. Further disclosed is a method of treating a bacterial or protozoal infection in a mammal in need thereof comprising contiguously administering to said mammal a single dose of an oral dosage form wherein said oral dosage form comprises azithromycin and an effective amount of an alkalizing agent. Additionally disclosed are azithromycin multiparticulates comprising azithromycin, a surfactant; and a pharmaceutically acceptable carrier.

124. 发明专利

PL377479A1 Kontrolowane uwalnianie substancji czynnej do środowiska o wysokiej zawartości tłuszczu 未知
公开(公告)号：PL377479A1
公开(公告)日：2006-02-06
申请号：PL37747903
申请日：2003-11-28
申请人： PFIZER PROD INC
发明人： CHIDLAW MARK BRIAN , FRIESEN DWAYNE THOMAS , HERBIG SCOTT MAX , NIGHTINGALE JAMES ALAN SCHRIVE , OKSANEN CYNTHIA ANN , WEST JAMES BLAIR
IPC分类号： A61K9/36 , A61K9/00 , A61K9/20 , A61K9/28 , A61K31/137 , A61K31/4985

125. 发明专利

CA2298238C CONTROLLED RELEASE BY EXTRUSION OF SOLID AMORPHOUS DISPERSIONS OF DRUGS 未知
公开(公告)号：CA2298238C
公开(公告)日：2005-10-25
申请号：CA2298238
申请日：2000-02-09
申请人： PFIZER PROD INC
发明人： CURATOLO WILLIAM JOHN , APPEL LEAH ELIZABETH , NIGHTINGALE JAMES ALAN SCHRIVE , HERBIG SCOTT MAX , THOMBRE AVINASH GOVIND
IPC分类号： A61K9/22 , A61K9/00 , A61K9/14 , A61K9/16 , A61K9/26 , A61K9/50 , A61K9/52 , A61K31/135 , A61K31/137 , A61K31/17 , A61K31/36 , A61K31/404 , A61K31/44 , A61K31/497 , A61K31/505 , A61K31/517 , A61K31/522 , A61K47/32 , A61K47/34 , A61K47/38 , A61K31/40 , A61K31/4422 , A61K45/00 , A61P9/12 , A61P13/00 , A61P25/18 , A61P29/00
摘要： Controlled release dosage forms for low solubility drugs are disclosed wherein an amorphous solid dispersion of the drug is coated with a non-dissolving and non-eroding coating that controls the influx of water to the core so as to cause extrusion of a portion of the core, as well as a method of treating a disease or disorder comprising administering such dosage form to a person.

126. 发明专利

BRPI0403935A 未知
公开(公告)号：BRPI0403935A
公开(公告)日：2005-08-09
申请号：BRPI0403935
申请日：2004-05-14
申请人： PFIZER PROD INC
发明人： HAGEN TIMOTHY ARTHUR , HERBIG SCOTT MAX , LO JULIAN BELKNAP , THOMBRE AVINASH GOVIND , APPEL LEAH ELISABETH , CREW MARSHALL DAVID , FRIESEN DWAYNE THOMAS , LYON DAVID KEITH , MCCRAY SCOTT BALDWIN , WEST JAMES BLAIR
IPC分类号： C07H17/00 , A61K9/00 , A61K9/16 , A61K9/20 , A61K31/7052 , A61K47/02 , A61K47/14 , A61K47/18 , A61K47/44 , A61P31/04
摘要： An oral dosage form comprising azithromycin and an effective amount of an alkalizing agent. Preferably, said oral dosage form comprises an effective amount of an alkalizing agent and an azithromycin multiparticulate wherein said multiparticulate comprises azithromycin, a mixture of glyceryl monobehenate, glyceryl dibehenate and glyceryl tribehenate, and a poloxamer. Typically, the oral dosage form includes any suitable oral dosing means such as a powder for oral suspension, a unit dose packet or sachet, a tablet or a capsule. Additionally disclosed is an oral suspension comprising azithromycin, an effective amount of an alkalizing agent and a vehicle. Preferably, the azithromycin is in multiparticulate form wherein said multiparticulate comprises azithromycin, a mixture of glyceryl monobehenate, glyceryl dibehenate and glyceryl tribehenate, and a poloxamer. Also disclosed is a method for reducing gastrointestinal side effects, associated with administering azithromycin to a mammal, comprising contiguously administering azithromycin and an effective amount of alkalizing agent to said mammal wherein the frequency of gastrointestinal side effects is lower than that experienced by administering an equal dose of azithromycin without said alkalizing agent. Further disclosed is a method of treating a bacterial or protozoal infection in a mammal in need thereof comprising contiguously administering to said mammal a single dose of an oral dosage form wherein said oral dosage form comprises azithromycin and an effective amount of an alkalizing agent. Additionally disclosed are azithromycin multiparticulates comprising azithromycin, a surfactant; and a pharmaceutically acceptable carrier.

127. 发明专利

AU2004216676A1 Azithromycin dosage forms with reduced side effects 未知
公开(公告)号：AU2004216676A1
公开(公告)日：2005-06-23
申请号：AU2004216676
申请日：2004-05-14
申请人： PFIZER PROD INC
发明人： APPEL LEAH ELIZABETH , THOMBRE AVINASH GOVIND , LO JULIAN BELKNAP , HERBIG SCOTT MAX , HAGEN TIMOTHY ARTHUR , WEST JAMES BLAIR , MCCRAY SCOTT BALDWIN , LYON DAVID KEITH , FRIESEN DWAYNE THOMAS , CREW MARSHALL DAVID
IPC分类号： A61K9/16 , A61K38/00

128. 发明专利

EE200300055A 未知
公开(公告)号：EE200300055A
公开(公告)日：2004-12-15
申请号：EEP200300055
申请日：2001-08-03
申请人： PFIZER PROD INC
发明人： APPEL LEAH ELIZABETH , BABCOCK WALTER CHRISTIAN , BEYERINCK RONALD ARTHUR , CHIDLAW MARK BRIAN , CURATOLO WILLIAM JOHN , FRIESEN DWAYNE THOMAS , HERBIG SCOTT MAX , THOMBRE AVINASH GOVIND
IPC分类号： A61K9/00 , A61K9/20 , A61K9/22 , A61K9/24 , A61K31/135 , A61K31/353 , A61K31/4178 , A61K31/4422 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/16 , A61K47/26 , A61K47/30 , A61K47/34 , A61K47/36 , A61K47/38 , A61K47/42
摘要： A controlled release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of geometric arrangements are disclosed.

129. 发明专利

PL360658A1 HYDROGEL-DRIVEN DRUG DOSAGE FORM 未知
公开(公告)号：PL360658A1
公开(公告)日：2004-09-20
申请号：PL36065801
申请日：2001-08-03
申请人： PFIZER PROD INC
发明人： APPEL LEAH ELIZABETH , BABCOCK WALTER C , BEYERINCK RONALD ARTHUR , CHIDLAW MARK BRIAN , CURATOLO WILLIAM JOHN , FRIESEN DWAYNE THOMAS , HERBIG SCOTT MAX , THOMBRE AVINASH GOVIND
IPC分类号： A61K9/00 , A61K9/20 , A61K9/22 , A61K9/24 , A61K31/135 , A61K31/353 , A61K31/4178 , A61K31/4422 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/16 , A61K47/26 , A61K47/30 , A61K47/34 , A61K47/36 , A61K47/38 , A61K47/42
摘要： A controlled release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of geometric arrangements are disclosed.

130. 发明专利

HRP20030082A2 HYDROGEL-DRIVEN DRUG DOSAGE FORM 未知
公开(公告)号：HRP20030082A2
公开(公告)日：2003-04-30
申请号：HRP20030082
申请日：2003-02-06
申请人： PFIZER PROD INC
发明人： APPEL LEAH ELIZABETH , BABCOCK WALTER CHRISTIAN , BEYERINCK RONALD ARTHUR , CHIDLAW MARK BRIAN , CURATOLO WILLIAM JOHN , FRIESEN DWAYNE THOMAS , HERBIG SCOTT MAX , THOMBRE AVINASH GOVIND
IPC分类号： A61K9/00 , A61K9/20 , A61K9/22 , A61K9/24 , A61K31/135 , A61K31/353 , A61K31/4178 , A61K31/4422 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/16 , A61K47/26 , A61K47/30 , A61K47/34 , A61K47/36 , A61K47/38 , A61K47/42
摘要： A controlled release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of geometric arrangements are disclosed.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式