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121. 发明申请

US20060158532A1 Image capturing apparatus and image capturing method 有权
公开(公告)号：US20060158532A1
公开(公告)日：2006-07-20
申请号：US11334359
申请日：2006-01-19
申请人： Kenichiro Ayaki , Koji Kobayashi
发明人： Kenichiro Ayaki , Koji Kobayashi
IPC分类号： H04N5/235
CPC分类号： H04N5/2352
摘要： An image signal obtained by a CCD image sensor is amplified by an amplifier. A gain of the amplifier is changed according to an ISO sensitivity. An AE circuit measures light intensity of a subject. According to the measured light intensity, a correct exposure time of the CCD image sensor is calculated. The exposure time of the CCD image sensor is changed by a CCD driver. In the exposure adjustment, a system controller increases the gain by making the ISO sensitivity higher such that the calculated exposure time becomes shorter than a predetermined anti-camera shake exposure time.

122. 发明申请

US20060153794A1 Hair tonics and method of screening the same 审中-公开
标题翻译：发质和筛选方法相同
公开(公告)号：US20060153794A1
公开(公告)日：2006-07-13
申请号：US11312549
申请日：2005-12-21
申请人： Toshihiko Hibino , Yumiko Tsuji , Tsutomu Soma , Sumiko Denda , Jotaro Nakanishi , Tadahito Takahashi , Kenichi Umishio , Koji Kobayashi
发明人： Toshihiko Hibino , Yumiko Tsuji , Tsutomu Soma , Sumiko Denda , Jotaro Nakanishi , Tadahito Takahashi , Kenichi Umishio , Koji Kobayashi
IPC分类号： A61K8/97 , A61K36/185
CPC分类号： A61Q5/00 , A61K8/498 , A61K8/64 , A61K8/97 , A61K31/366 , A61K36/185 , A61K36/30 , A61K36/48 , A61K36/53 , A61K36/73 , A61K36/82 , A61K36/87 , A61K36/8994 , A61K38/06 , A61K38/55 , A61K45/06 , A61K2800/782 , A61Q7/00 , A61K2300/00
摘要： There is provided a hair tonic comprising at least two of an inhibitor against 5α reductase type 2, an inhibitor against transforming growth factor β2, and an inhibitor against caspase-3; a method comprising screening for at least two of inhibition against 5α reductase type 2, inhibition against transforming growth factor β2, and inhibition against caspase-3, or comprising screening for inhibition against caspase-3 and then for apoptosis inhibition, and a hair loss inhibitor having the effect of inhibiting caspase-3, and a hair loss inhibitor having the effect of inhibiting caspase-3 and of inhibiting apoptosis.
摘要翻译：提供了包含至少两种抑制剂5型5α还原酶2型抑制剂，抗转化生长因子β2的抑制剂和抗半胱天冬酶-3抑制剂的滋补剂; 一种方法包括筛选至少两种对2型5α还原酶的抑制，对转化生长因子β2的抑制和对半胱天冬酶-3的抑制，或包括筛选对半胱天冬酶-3的抑制，然后筛选凋亡抑制，以及脱发抑制剂具有抑制半胱天冬酶-3的效果，以及具有抑制半胱天冬酶-3的作用并抑制细胞凋亡的脱发抑制剂。

123. 发明申请

US20060107253A1 Method and apparatus for generating specification data 有权
标题翻译：用于生成规格数据的方法和装置
公开(公告)号：US20060107253A1
公开(公告)日：2006-05-18
申请号：US11065711
申请日：2005-02-25
申请人： Shin-ichi Sano , Hiroshi Sunaga , Koji Kobayashi
发明人： Shin-ichi Sano , Hiroshi Sunaga , Koji Kobayashi
IPC分类号： G06F9/44
CPC分类号： G06F8/10
摘要： When a source program written in Java or the like and using methods of BigDecimal class, a priority conforming to a predetermined arithmetic rule is identified for an arithmetic operational method included in an arithmetic operation statement, and the arithmetic operational method and the identified priority are registered into a storage device. Then, in a case where it is judged based on data stored in the storage device that a plurality of arithmetic operational methods are included in an arithmetic operational statement, and an arithmetic operational method with low priority is defined as an instance of an arithmetic operational method with high priority, following processing is carried out to generate specification data, that is, the arithmetic operational method with low priority and an instance and argument of the arithmetic operational method with low priority are converted into a first subexpression using an arithmetic operational sign in accordance with a predetermined rule. Then, parentheses representing that the arithmetic operation are carried out with priority is added to the first subexpression. In addition, the arithmetic operational method with high priority and an argument of the arithmetic operational method with high priority are converted into a second subexpression using an arithmetic operational sign in accordance with the predetermined rule. Finally, the second subexpression is linked with the first subexpression.
摘要翻译：当使用Java等编写并使用BigDecimal类的方法的源程序时，针对包括在算术运算语句中的算术运算方法来识别符合预定算术规则的优先级，并且记录算术运算方法和识别的优先级进入存储设备。然后，在根据存储装置中存储的数据判断在算术运算语句中包含多种算术运算方法的情况下，将低优先级的算术运算方法定义为算术运算方式的一例高优先级，进行以下处理以生成指定数据，即具有低优先级的算术运算方法，并且具有低优先级的算术运算方法的实例和自变量根据算术运算符号转换为第一子表达式具有预定规则。然后，代表优先执行算术运算的括号被加到第一子表达式中。此外，具有高优先级的算术运算方法和具有高优先级的算术运算方法的自变量根据预定规则被转换为使用算术运算符号的第二子表达式。最后，第二个子表达式与第一个子表达式相关联。

124. 发明申请

US20050148474A1 Plant activator 审中-公开
标题翻译：植物激活剂
公开(公告)号：US20050148474A1
公开(公告)日：2005-07-07
申请号：US11058368
申请日：2005-02-16
申请人： Mineyuki Yokoyama , Shoko Yamaguchi , Toshii Iida , Kiyotaka Kojima , Koji Kobayashi , Osamu Tanaka
发明人： Mineyuki Yokoyama , Shoko Yamaguchi , Toshii Iida , Kiyotaka Kojima , Koji Kobayashi , Osamu Tanaka
IPC分类号： A01N37/42 , A01N37/00
CPC分类号： A01N37/42
摘要： An object of the present invention is to determine novel means of activating plants; more particularly, means or controlling plant growth, such as means of promoting growth, means of controlling dormancy, means of imparting tolerance against stress for plants (dryness, high or low temperatures, osmotic pressure, etc.), and means of preventing aging. The present inventors have found that the above object can be achieved by providing plant activators containing, as an active ingredient, C4-C24 ketol fatty acids, in particular, 9-hydroxy-10-oxo-12(Z),15(Z)-octadecadienoic acid.
摘要翻译：本发明的目的是确定活化植物的新方法; 更具体地说，是指或控制植物生长，例如促进生长的手段，控制休眠的手段，赋予植物胁迫耐受性的手段（干燥，高温或低温，渗透压等）以及防止老化的手段。本发明人已经发现，上述目的可以通过提供含有作为有效成分的C 4 -C 24脂肪醇脂肪酸的植物活化剂来实现，特别是9 - 羟基-10-氧代-12（Z），15（Z） - 十八碳二烯酸。

125. 发明申请

US20050009808A1 Azabicyclo compound matrix metalloprotease inibitor and skin preparation 失效
标题翻译：氮杂双环化合物基质金属蛋白酶抑制剂和皮肤制剂
公开(公告)号：US20050009808A1
公开(公告)日：2005-01-13
申请号：US10495370
申请日：2002-11-13
申请人： Takuya Hiruma , Koji Kobayashi , Shinji Inomata
发明人： Takuya Hiruma , Koji Kobayashi , Shinji Inomata
IPC分类号： A61K8/49 , A61K31/403 , A61K31/439 , A61K31/4439 , A61K31/55 , A61P1/02 , A61P1/04 , A61P17/00 , A61P17/16 , A61P19/02 , A61P19/04 , A61P19/08 , A61P19/10 , A61P25/00 , A61P27/02 , A61P29/00 , A61P35/04 , A61P43/00 , A61Q19/00 , A61Q19/08 , C07D209/52 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/14 , C07D451/06 , C07D453/06 , C07D471/08 , C07D453/02 , A61K31/4745
CPC分类号： A61Q19/08 , A61K8/0212 , A61K8/492 , A61K31/403 , A61K31/439 , A61K31/4439 , A61K31/55 , A61K2800/782 , A61Q1/02 , A61Q19/00 , C07D209/52 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/14 , C07D451/06 , C07D453/06 , C07D471/08
摘要： An azabicyclo compound (I) or a salt thereof in accordance with the present invention has an excellent inhibiting action on matrix metalloproteases (MMPs) activity, and is useful for pharmaceutical, cosmetic and skin external compositions. wherein R is H, alkyl, heteroalkyl, aryl, heteroaryl, arylalkyl, heteroarylalkyl, acyl, COOR1, carbamoyl or SO2R2 (wherein R1 and R2 each are alkyl, heteroalkyl, aryl, heteroaryl, arylalkyl or heteroarylalkyl); X is methylene, ethylene or propylene; and is a single bond or a double bond.
摘要翻译：根据本发明的氮杂二环化合物（I）或其盐对基质金属蛋白酶（MMPs）活性具有优异的抑制作用，并且可用于药物，化妆品和皮肤外用组合物。其中R是H，烷基，杂烷基，芳基，杂芳基，芳基烷基，杂芳基烷基，酰基，COOR 1，氨基甲酰基或SO 2 R 2（其中R 1和R 2各自是烷基，杂烷基，芳基，杂芳基，芳基烷基或杂芳基烷基）; X是亚甲基，亚乙基或亚丙基; 并且是单键或双键。

126. 发明授权

US06580227B2 Plasma display panel, manufacturing method thereof, and plasma display 失效
标题翻译：等离子体显示面板，其制造方法和等离子显示器
公开(公告)号：US06580227B2
公开(公告)日：2003-06-17
申请号：US10112725
申请日：2002-04-02
申请人： Koji Kobayashi
发明人： Koji Kobayashi
IPC分类号： H05B3700
CPC分类号： H01J11/32 , H01J11/12 , H01J11/24 , H01J2211/245 , H01J2211/323
摘要： A mesh barrier rib structure to separate display cells is provided, and each of the display cells is completely separated from the adjacent cells. Bus electrodes are provided to overlap transparent electrodes. The bus electrodes are for example made of a layered body including a white Ag thin film and a black RuO2 thin film. The transparent electrode and the bus electrode form a scan electrode, while the transparent electrode and the bus electrode form a common electrode. The bus electrodes are provided in the closest positions to the surface discharge gap between the transparent electrodes. Therefore, priming discharge is generated in the vicinity of the discharge gap, and light emission can be restrained in the priming period.
摘要翻译：提供了用于分离显示单元的网状隔壁结构，并且每个显示单元与相邻单元完全分离。提供总线电极以重叠透明电极。总线电极例如由包括白色Ag薄膜和黑色RuO 2薄膜的层状体制成。透明电极和总线电极形成扫描电极，而透明电极和总线电极形成公共电极。总线电极设置在与透明电极之间的表面放电间隙最接近的位置。因此，在放电间隙附近产生引发放电，能够在启动期间抑制发光。

127. 发明授权

US06468734B2 Container for measurement of cell functions, kit for measurement of cell functions and method for measuring cell functions 有权
标题翻译：用于测量细胞功能的容器，用于测量细胞功能的试剂盒和测量细胞功能的方法
公开(公告)号：US06468734B2
公开(公告)日：2002-10-22
申请号：US09753518
申请日：2001-01-04
申请人： Koji Kobayashi , Yuji Setoguchi , Kiyoshi Kuriyama
发明人： Koji Kobayashi , Yuji Setoguchi , Kiyoshi Kuriyama
IPC分类号： G01N3350
CPC分类号： G01N33/6869 , G01N33/96 , Y10S435/809 , Y10S435/81 , Y10S435/969 , Y10S435/97 , Y10S435/971 , Y10S435/973 , Y10S435/974 , Y10S436/81
摘要： An object is to obtain a container for measurement of cell functions which is simplified in operation, less risky and capable of measuring the cell functions very accurately. A container for measurement of cell functions, for use in the determination of a physiologically active substance produced by blood cells, is constituted such that an amount of material capable of inducing production of the physiologically active substance, when extracted by collecting water of a volume equal to a liquid volume to be subjected to measurement, is controlled at a level insufficient to induce production of the physiologically active substance from the blood cells. A container for measurement of cell functions in which a material capable of inducing production of a physiologically active substance in blood when contacted with the blood is accommodated in such a condition as being contactable with blood, and in which an amount of the material capable of inducing production of the physiologically active substance in the container before use is limited to a level insufficient to influence a measured value of the physiologically active substance.
摘要翻译：本发明的目的是获得用于测量细胞功能的容器，其操作简单，风险较小并且能够非常精确地测量细胞功能。1。一种用于测量细胞功能的容器，用于测定由血细胞被构成为使得能够诱导生理生物活性物质的物质的量通过收集与待测量的液体体积相同的体积的水进行提取时被控制在不足以诱导生产来自血细胞的生理活性物质。用于测量细胞功能的容器，其中当与血液接触时能够诱导在血液中产生生理活性物质的物质的容器被容纳在与血液接触的状态下，并且其中能够诱导的物质的量在使用前将容器中的生理活性物质的产生限制在不足以影响生理活性物质的测定值的水平。

128. 发明授权

US06458548B2 Containers and kits for the determination of cell functions, and method for the determination thereof 失效
标题翻译：用于测定细胞功能的容器和试剂盒及其测定方法
公开(公告)号：US06458548B2
公开(公告)日：2002-10-01
申请号：US09068027
申请日：1998-04-01
申请人： Koji Kobayashi , Yuji Setoguchi , Kiyoshi Kuriyama
发明人： Koji Kobayashi , Yuji Setoguchi , Kiyoshi Kuriyama
IPC分类号： G01N3353
CPC分类号： G01N33/6869 , G01N33/96 , Y10S435/809 , Y10S435/81 , Y10S435/969 , Y10S435/97 , Y10S435/971 , Y10S435/973 , Y10S435/974 , Y10S436/81
摘要： A container for measurement of cell functions, for use in the determination of a physiologically active substance produced by blood cells, is constituted such that an amount of material capable of inducing production of the physiologically active substance, when extracted by collecting water of a volume equal to a liquid volume to be subjected to measurement, is controlled at a level insufficient to induce production of the physiologically active substance from the blood cells. A container for measurement of cell functions in which a material capable of inducing production of a physiologically active substance in blood when contacted with the blood is accommodated in such a condition as being contactable with blood, and in which an amount of the material capable of inducing production of the physiologically active substance in the container before use is limited to a level insufficient to influence a measured value of the physiologically active substance.
摘要翻译：用于测定由血细胞产生的生理活性物质的细胞功能测定用容器构成为能够诱导生成生理活性物质的物质的量，当通过收集体积相等的水提取时对于要进行测量的液体体积被控制在不足以诱导从血细胞产生生理活性物质的水平。用于测量细胞功能的容器，其中当与血液接触时能够诱导在血液中产生生理活性物质的物质的容器被容纳在与血液接触的状态下，并且其中能够诱导的物质的量在使用前将容器中的生理活性物质的产生限制在不足以影响生理活性物质的测定值的水平。

129. 发明授权

US06195460B1 Pattern extraction apparatus 失效
标题翻译：模式提取装置
公开(公告)号：US06195460B1
公开(公告)日：2001-02-27
申请号：US09297537
申请日：1999-04-30
申请人： Koji Kobayashi , Hiroshi Nakajima , Takafumi Aoki , Masayuki Kawamata , Tatsuo Higuchi
发明人： Koji Kobayashi , Hiroshi Nakajima , Takafumi Aoki , Masayuki Kawamata , Tatsuo Higuchi
IPC分类号： G06K946
CPC分类号： G06K9/522
摘要： Collation Fourier image data (FIG. 1D) FB generated by performing the two-dimensional discrete Fourier transform (DFT) for the image data (FIG. 1C) of a collation pattern is synthesized with registration Fourier image data (FIG. 1B) generated by performing the two-dimensional DFT for the image data of a registration pattern. After amplitude suppression processing is performed for the resultant data, two-dimensional DFT is performed. A correlation peak is extracted from a correlation component area which appears in the synthesized Fourier image data (FIG. 1E) for which the two-dimensional DFT has been performed. A predetermined area including this correlation peak is then masked (FIG. 1F). The two-dimensional DFT is performed for the masked synthesized Fourier image data, and amplitude restoration processing is performed for the data. The resultant data is re-synthesized with the registration Fourier image data FA, and the two-dimensional IDFT is performed for the synthesized data. With this processing, image data containing a difference pattern like the one shown in FIG. 1G or a moving pattern can be obtained.
摘要翻译：通过对核对图案的图像数据（图1C）执行二维离散付里叶变换（DFT）生成的核对付里叶图像数据（图1D），由登记付里叶图象数据（图1B）合成，对注册图案的图像数据执行二维DFT。在对所得数据进行幅度压缩处理之后，执行二维DFT。从出现在执行了二维DFT的合成付里叶图像数据（图1E）中的相关分量区域提取相关峰值。然后掩蔽包括该相关峰的预定区域（图1F）。对被掩蔽的合成付里叶图像数据执行二维DFT，并且对数据执行幅度恢复处理。所得到的数据与登记付里叶图象数据FA重新合成，并且对合成数据执行二维IDFT。通过该处理，包含类似于图1所示的差异模式的图像数据。可以获得1G或移动图案。

130. 发明授权

US6057337A 1,2-DI-substituted piperidine derivative, hair growth promoter and external composition for skin using the same 有权
标题翻译： 1,2-DI取代的哌啶衍生物，毛发生长促进剂和使用其的皮肤外用组合物
公开(公告)号：US6057337A
公开(公告)日：2000-05-02
申请号：US239960
申请日：1999-01-29
申请人： Koji Kobayashi , Hirotada Fukunishi , Kenichi Umishio , Akihiro Ishino
发明人： Koji Kobayashi , Hirotada Fukunishi , Kenichi Umishio , Akihiro Ishino
IPC分类号： C07D211/22 , C07D211/26 , C07D401/12 , C07D521/00 , A61K7/06
CPC分类号： C07D231/12 , C07D211/22 , C07D211/26 , C07D233/56 , C07D249/08 , C07D401/12
摘要： A 1,2-di-substituted piperidine derivative or a salt thereof expressed by the following Formula (I): ##STR1## wherein one of A and B is a hydrocarbon group of C.sub.1-30 expressed by R.sup.1 and the other is --(CH.sub.2)n-NR.sup.2 R.sup.3 ; Y is --CO--, --CONR.sup.5 -- or --COO--; Z is --O--, --OCO--, --OCONR.sup.6 -- or --NR.sup.6 --; R.sup.2 and R.sup.3 individually represent a hydrogen a lower alkyl, a phenyl or a benzyl group, or together represent a heterocycle having 3-7 members; --NR.sup.5 --(CH.sub.2)n-NR.sup.2 R.sup.3 and --NR.sup.6 --(CH.sub.2)n-NR.sup.2 R.sup.3 of --(Y).sub.1 --A and --Z--B may be the following Group W: ##STR2## wherein ring E is a heterocycle of 6 or 7 members including two nitrogen atoms and R.sup.2 is a hydrogen, a lower alkyl, a phenyl or a benzyl group; R.sup.4 is a hydrogen, a halogen, a lower alkyl, a lower acyl, a nitro, a cyano, a lower alkoxycarbonyl, a carbamoyl, a lower alkylcarbamoyl, a lower alkylamino, a lower acylamino, a lower alkoxy or a lower acyloxy group; each of R.sup.5 and R.sup.6 is a hydrogen, a lower alkyl, a lower acyl, a lower alkylcarbamoyl group, or a part of said ring E; l is 0 or 1; m is an integer of 2-5; and n is an integer of 0-5. The 1,2-di-substituted piperidine derivative or the salt thereof has excellent hair growth and regrowth promoting effects, which are useful for care, improvement or prevention of hair loss in mammals and, in particular, in human.
摘要翻译：由下式（I）表示的1,2-二取代的哌啶衍生物或其盐：其中A和B中的一个为由R1表示的C1-30的烃基，另一个为 - （CH 2）n - NR2R3; Y是-CO - ， - CONR 5 - 或-COO-; Z是-O - ， - OCO - ， - OCONR 6 - 或-NR 6 - ; R2和R3各自表示氢，低级烷基，苯基或苄基，或一起表示具有3-7个成员的杂环; - （Y）1-A和-ZB的-NR 5 - （CH 2）n -NR 2 R 3和-NR 6 - （CH 2）n -NR 2 R 3可以是以下W组：其中环E是6或7个成员的杂环，包括两个氮原子，R 2为氢，低级烷基，苯基或苄基; R4是氢，卤素，低级烷基，低级酰基，硝基，氰基，低级烷氧基羰基，氨基甲酰基，低级烷基氨基甲酰基，低级烷基氨基，低级酰基氨基，低级烷氧基或低级酰氧基。 R5和R6各自为氢，低级烷基，低级酰基，低级烷基氨基甲酰基或所述环E的一部分; l为0或1; m为2-5的整数; n为0-5的整数。 1,2-二取代的哌啶衍生物或其盐具有优异的毛发生长和再生长促进效果，其可用于哺乳动物，特别是人的护发，改善或预防脱发。

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