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    • 111. 发明申请
    • Determination of a measure of a glycation end-product or disease state using tissue fluorescence
    • 使用组织荧光测定糖基化终产物或疾病状态的量度
    • US20050148834A1
    • 2005-07-07
    • US10972173
    • 2004-10-22
    • Edward HullMarwood EdigerChristopher BrownJohn MaynardRobert Johnson
    • Edward HullMarwood EdigerChristopher BrownJohn MaynardRobert Johnson
    • A61B5/00G01N20060101
    • A61B5/1455A61B5/0059A61B5/0064A61B5/0066A61B5/0068A61B5/0071A61B5/0075A61B5/14532A61B5/412A61B5/441
    • A method of determining a measure of a tissue state (e.g., glycation end-product or disease state) in an individual. A portion of the tissue of the individual is illuminated with excitation light, then light emitted by the tissue due to fluorescence of a chemical with the tissue responsive to the excitation light is detected. The detected light can be combined with a model relating fluorescence with a measure of tissue state to determine a tissue state. The invention can comprise single wavelength excitation light, scanning of excitation light (illuminating the tissue at a plurality of wavelengths), detection at a single wavelength, scanning of detection wavelengths (detecting emitted light at a plurality of wavelengths), and combinations thereof. The invention also can comprise correction techniques that reduce determination errors due to detection of light other than that from fluorescence of a chemical in the tissue. For example, the reflectance of the tissue can lead to errors if appropriate correction is not employed. The invention can also comprise a variety of models relating fluorescence to a measure of tissue state, including a variety of methods for generating such models. Other biologic information can be used in combination with the fluorescence properties to aid in the determination of a measure of tissue state. The invention also comprises apparatuses suitable for carrying out the method, including appropriate light sources, detectors, and models (for example, implemented on computers) used to relate detected fluorescence and a measure of tissue state.
    • 确定个体中组织状态(例如,糖基化终产物或疾病状态)的量度的方法。 用激发光照射个体组织的一部分,然后检测由组织响应于激发光的化学物质的荧光而由组织发出的光。 检测到的光可以与将荧光与组织状态的测量相关联的模型组合以确定组织状态。 本发明可以包括单波长激发光,激发光的扫描(以多个波长照射组织),单个波长的检测,检测波长的扫描(检测多个波长的发射光)及其组合。 本发明还可以包括校正技术,其减少由于检测到除了组织中的化学物质的荧光以外的光的测定误差。 例如,如果不采用适当的校正,组织的反射率可能导致错误。 本发明还可以包括将荧光与组织状态的测量相关联的各种模型,包括用于产生这种模型的各种方法。 其他生物信息可与荧光性质结合使用,有助于测定组织状态。 本发明还包括适于执行该方法的装置,包括用于检测荧光和组织状态测量的适当的光源,检测器和模型(例如,在计算机上实现)。
    • 116. 发明授权
    • Telecommunicaion user account management system and method
    • 电信用户账户管理系统和方法
    • US5696906A
    • 1997-12-09
    • US401602
    • 1995-03-09
    • J. Michael PetersBarry BattistaChristopher Brown
    • J. Michael PetersBarry BattistaChristopher Brown
    • H04M15/00H04N7/10H04N7/173G06F17/60
    • H04N7/17318G06Q30/0283G06Q30/04G06Q40/12H04M15/00H04N7/10H04N7/17354
    • The present is an integrated computerized system and method of telecommunication user account management. The invention creates, maintains, processes and analyzes data regarding individual users for telecommunication services. Billing for individual users is generated. The user data is analyzed and reports for all or part of the user data are prepared and generated. Ancillary functions are enabled, including word processing, editing, e-mail, and other functions. The invention is applicable to subscriber telecommunication services, and pay-for-use services, and the user may be a subscriber or a non-subscriber. The invention is applicable to multi-channel telecommunication services, or single channel multi-service telecommunications, or single channel single service telecommunications. Such telecommunication services may include cable television, telephone, video, audio, on-line databases, television, radio, music video, video juke box, pay-for-view, video-on-demand, interactive TV, home-shopping, video conferences, telephone conferences, interfacing to imaging systems, automatic telephone call charge-backs ("900" numbers), and other telecommunication services which may not yet be invented at this time. The current preferred embodiment of the invention is for subscriber account management for cable television services.
    • 目前是电信用户账户管理的综合计算机化系统和方法。 本发明创建,维护,处理和分析关于电信业务的个人用户的数据。 生成单个用户的帐单。 分析用户数据,并准备和生成用于全部或部分用户数据的报告。 启用辅助功能,包括文字处理,编辑,电子邮件等功能。 本发明适用于用户电信业务和付费用途业务,用户可以是用户或非用户。 本发明适用于多信道电信业务,单信道多业务电信,或单信道单业务电信。 这样的电信服务可以包括有线电视,电话,视频,音频,在线数据库,电视,广播,音乐视频,视频点唱机,付费视频点播,交互式电视,家庭购物,视频 会议,电话会议,与成像系统的接口,自动电话呼叫回拨(“900”号码)以及此时可能尚未发明的其他电信业务。 本发明的当前优选实施例是用于有线电视服务的用户帐户管理。