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    • 116. 发明授权
    • Advanced rapid thermal processing (RTP) using a linearly-moving heating assembly with an axisymmetric and radially-tunable thermal radiation profile
    • 先进的快速热处理(RTP),使用具有轴对称和径向可调谐热辐射轮廓的线性移动加热组件
    • US06768084B2
    • 2004-07-27
    • US10261907
    • 2002-09-30
    • Yong LiuJeff P. Hebb
    • Yong LiuJeff P. Hebb
    • F27B514
    • H01L21/67248F27B17/0025F27D11/00F27D19/00F27D21/0014H01L21/67109H01L21/67115
    • A system and a method for thermally processing a semiconductor substrate are disclosed which provide a heater chamber and a process chamber environmentally isolated from one another by a thermally-transparent plate. A heater assembly situated within the heater chamber comprises one or more quasi-continuous heater elements, and is operable to linearly translate with respect to the process chamber by a linear translation assembly. Thermal radiation is transmitted from the heater elements through the plate toward a substrate situated within the process chamber, wherein one or more temperature sensors measure a temperature associated with one or more respective locations on the substrate. A controller coupled to the one or more temperature sensors, heater assembly, and linear translation assembly controls the thermal radiation emitted by the heater assembly, as well as a distance between the heater assembly and the substrate, wherein the control is based on the one or more measured temperatures.
    • 公开了一种用于热处理半导体衬底的系统和方法,其提供通过热透明板彼此隔离的加热室和处理室。 位于加热器室内的加热器组件包括一个或多个准连续加热器元件,并且可操作以通过线性平移组件相对于处理室线性平移。 热辐射从加热器元件通过板传送到位于处理室内的衬底,其中一个或多个温度传感器测量与衬底上的一个或多个相应位置相关联的温度。 耦合到一个或多个温度传感器,加热器组件和线性平移组件的控制器控制由加热器组件发射的热辐射,以及加热器组件和衬底之间的距离,其中控制基于一个或多个 更多的测量温度。
    • 119. 发明授权
    • In vitro assay for inhibitors of the intron self-splicing reaction in
Pneumocystis carinii
    • 体外测定卡氏肺囊虫内含子自剪接反应抑制剂
    • US5849484A
    • 1998-12-15
    • US491690
    • 1995-06-19
    • Michael J. LeibowitzYong Liu
    • Michael J. LeibowitzYong Liu
    • C07K14/44C12Q1/68C07H21/04C12P19/34
    • C12Q1/6895C07K14/44
    • The present invention pertains to an in vitro method for assaying for an inhibitor of the catalytic Group I self-splicing intron reaction in the nuclear rRNA genes of Pheumocystis carinii which comprises the steps of (a) providing a DNA template containing the intron (I) from the 26S rRNA gene in Pneumocystis carinii and a portion of the 5' and 3' flanking exons (E1 and E2, respectively) between nucleotides 1963 and 2267 of 26S rRNA (660 nucleotides of amplified rRNA gene including the group I intron); (b) preparing an RNA precursor by transcription of the DNA template in the presence of labeled nucleoside triphosphates to produce a labeled RNA precursor (E1-I-E2); (c) purifying the RNA precursor; (d) incubating the RNA precursor and the inhibitor in the presence of guanosine triphosphate and magnesium ions; and (e) determining the degree of inhibition by the inhibitor on the intron splicing reaction in the RNA precursor by measuring the amount of labeled splicing intermediates and splicing products.
    • 本发明涉及用于测定卡氏囊霉核核rRNA基因中催化I组自剪接内含子反应抑制剂的体外方法,其包括以下步骤:(a)提供含有内含子(I)的DNA模板, 来自卡氏肺囊虫中的26S rRNA基因和26S rRNA核苷酸1963和2267之间的5'和3'侧翼外显子(分别为E1和E2)的一部分(包括第I组内含子的扩增rRNA基因的660个核苷酸); (b)通过在标记的三磷酸核苷存在下转录DNA模板来制备RNA前体以产生标记的RNA前体(E1-I-E2); (c)纯化RNA前体; (d)在三磷酸鸟苷和镁离子存在下孵育RNA前体和抑制剂; 和(e)通过测量标记的剪接中间体和拼接产物的量来确定抑制剂对RNA前体中内含子剪接反应的抑制程度。