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111. 发明授权

US07804447B2 Method for determining positions of contacts 失效
标题翻译：确定触点位置的方法
公开(公告)号：US07804447B2
公开(公告)日：2010-09-28
申请号：US12241598
申请日：2008-09-30
申请人： Yong-Hui Xiao , Li-Rong Zhang
发明人： Yong-Hui Xiao , Li-Rong Zhang
IPC分类号： G01S19/42 , G01C21/00
CPC分类号： G01S5/0027
摘要： A method for determining the positions of contacts through a global positioning system (GPS) is disclosed. The method includes sending position requests to the contacts, feeding back the current position information of the contacts to a GPS receiver of a user after receiving position requests, searching the contacts located within a same geographical region as the user according to the feedback information and displaying a list of the contacts to the user in the same geographical region.
摘要翻译：公开了一种通过全球定位系统（GPS）确定触点位置的方法。该方法包括向联系人发送位置请求，在接收到位置请求之后，将联系人的当前位置信息反馈给用户的GPS接收器，根据反馈信息搜索位于与用户相同的地理区域内的联系人，并且显示在同一地理区域的用户的联系人列表。

112. 发明申请

US20100182626A1 PRINTER AND METHOD FOR PRINTING 失效
标题翻译：打印机和打印方法
公开(公告)号：US20100182626A1
公开(公告)日：2010-07-22
申请号：US12551718
申请日：2009-09-01
申请人： YI-FANG WU , YONG-HUI XIAO , LI-RONG ZHANG
发明人： YI-FANG WU , YONG-HUI XIAO , LI-RONG ZHANG
IPC分类号： G06F3/12 , G06K15/02
CPC分类号： G06F3/1247 , B41J29/393 , G06F3/1221 , Y02D10/1592
摘要： A printer includes a data receiving unit, a print mechanism, a print controlling module and a power management module. The data receiving unit is capable of receiving a file from a client. The print mechanism is used for printing out the file into hard copy. The print controlling module is connected to the print mechanism for processing the file. The power management module is capable of detecting activity of the data receiving unit and supplying power to the printing controlling module and the print mechanism. When no file is received by the data receiving unit for a predetermined time, the power management module is capable of cutting off the power to print management module and the print mechanism.
摘要翻译：打印机包括数据接收单元，打印机构，打印控制模块和电源管理模块。数据接收单元能够从客户端接收文件。打印机构用于将文件打印成硬拷贝。打印控制模块连接到用于处理文件的打印机构。电源管理模块能够检测数据接收单元的活动并向打印控制模块和打印机构供电。当数据接收单元在预定时间内没有接收到文件时，电源管理模块能够切断打印管理模块和打印机构的电源。

113. 发明申请

US20100055036A1 PET VISUALIZATION OF AMYLOID-ASSOCIATED NEUROINFLAMMATION IN THE BRAIN 审中-公开
标题翻译：在脑中的AMYLOID相关神经炎症的PET可视化
公开(公告)号：US20100055036A1
公开(公告)日：2010-03-04
申请号：US12531051
申请日：2008-03-12
申请人： Tetsuya Suhara , Kazutoshi Suzuki , Makoto Higuchi , Ming-Rong Zhang , Jun Maeda , Bin Ji
发明人： Tetsuya Suhara , Kazutoshi Suzuki , Makoto Higuchi , Ming-Rong Zhang , Jun Maeda , Bin Ji
IPC分类号： A61K51/00 , C07C233/00
CPC分类号： A61K51/04 , A61B6/037 , A61B6/508
摘要： The present invention relate to a method for monitoring a response to a therapy on a mammal having a neurodegenerative or neuroinflammatory disorder. According to a preferred embodiment, the method comprising the steps of:a) imaging the mammal using a radio-labeled peripheral benzodiazepine receptor ligand;b) administrating in the mammal at least one anti-amyloid or anti-neuroinflammatory agent;c) imaging the mammal of step b) using a radio-labeled peripheral benzodiazepine receptor ligand; andd) detecting the level of CNS neuroinflammation by the signals from the radio-labeled peripheral benzodiazepine receptor ligand.
摘要翻译：本发明涉及用于监测对具有神经变性或神经炎症性疾病的哺乳动物的治疗反应的方法。根据优选实施方案，所述方法包括以下步骤：a）使用放射性标记的外周苯并二氮杂受体配体对哺乳动物进行成像; b）在哺乳动物中施用至少一种抗淀粉样蛋白或抗神经炎症药物; c）使用放射性标记的外周苯并二氮杂受体配体对步骤b）的哺乳动物进行成像; 和d）通过来自放射性标记的外周苯并二氮杂受体配体的信号检测CNS神经炎症的水平。

114. 发明申请

US20100047923A1 TWO HELIX BINDERS 有权
标题翻译：两个HELIX BINDERS
公开(公告)号：US20100047923A1
公开(公告)日：2010-02-25
申请号：US12337948
申请日：2008-12-18
申请人： Rong Zhang , Faisal Ahmed Syud , Jack Mathew Webster
发明人： Rong Zhang , Faisal Ahmed Syud , Jack Mathew Webster
IPC分类号： G01N33/566 , C07K14/00
CPC分类号： C07K14/31
摘要： An isolated polypeptide, Z domain, derived from B domain of Staphylococcal protein A, comprising a pair of anti-parallel alpha helices that are capable of binding a target, is provided herein. Introduction of different natural amino acid mutations in the polypeptide are provided here. Also provided are methods of using the two-helix binders.
摘要翻译：衍生自葡萄球菌蛋白A的B结构域的分离的多肽Z结构域，其包含能够结合靶的一对反平行α螺旋。在此提供了多肽中不同天然氨基酸突变的引入。还提供了使用双螺旋粘合剂的方法。

115. 发明申请

US20100041073A1 TWO HELIX BINDERS 有权
标题翻译：两个HELIX BINDERS
公开(公告)号：US20100041073A1
公开(公告)日：2010-02-18
申请号：US12337933
申请日：2008-12-18
申请人： Joshua Kendall Hoerner , Rong Zhang , Faisal Ahmed Syud , Jack Mathew Webster
发明人： Joshua Kendall Hoerner , Rong Zhang , Faisal Ahmed Syud , Jack Mathew Webster
IPC分类号： G01N33/574 , C07K14/31 , G01N33/566
CPC分类号： C07K14/31 , A61K49/0056 , A61K49/085 , A61K49/14 , A61K51/088
摘要： An isolated polypeptide, Z domain, derived from B domain of Staphylococcal protein A, comprising a pair of anti-parallel alpha helices that are capable of binding a target, is provided herein. Introduction of a covalent bridge between two modified amino acids in the polypeptide is provided here. Also provided are methods of using the two-helix binders.
摘要翻译：衍生自葡萄球菌蛋白A的B结构域的分离的多肽Z结构域，其包含能够结合靶的一对反平行α螺旋。这里提供了多肽中两个修饰的氨基酸之间的共价桥的引入。还提供了使用双螺旋粘合剂的方法。

116. 发明授权

US07565236B2 Airflow estimation method and apparatus for internal combustion engine 有权
标题翻译：内燃机气流估计方法及装置
公开(公告)号：US07565236B2
公开(公告)日：2009-07-21
申请号：US11780508
申请日：2007-07-20
申请人： Raymond Claude Turin , Rong Zhang , Man-Feng Chang
发明人： Raymond Claude Turin , Rong Zhang , Man-Feng Chang
IPC分类号： G06F19/00 , G01M19/00
CPC分类号： F02D41/18 , F02D2200/0406
摘要： A method of estimating an air charge in at least one combustion cylinder of an internal combustion engine includes calculating cylinder mass air flow based upon a modified volumetric efficiency parameter; and calculating the intake throttle mass air flow based upon a throttle air flow discharge parameter and a fuel enrichment factor. Three models including a mean-value cylinder flow model, a manifold dynamics model, and a throttle flow model are provided to estimate the air charge in the at least one combustion cylinder and to control delivery of fuel to the fuel delivery system.
摘要翻译：一种估计内燃机的至少一个燃烧气缸中的空气装料的方法包括：基于改进的容积效率参数计算气缸质量空气流量; 以及基于节气门气流排出参数和燃料浓缩因子计算进气节气门质量空气流量。提供包括平均值气缸流量模型，歧管动力学模型和节气门流量模型的三个模型以估计至少一个燃烧气缸中的空气充量并且控制燃料输送到燃料输送系统。

117. 发明申请

US20080139787A1 Fluorine-labeled compounds 有权
标题翻译：氟标记化合物
公开(公告)号：US20080139787A1
公开(公告)日：2008-06-12
申请号：US11606898
申请日：2006-11-30
申请人： Omayra Padilla De Jesus , Faisal Ahmed Syud , Rong Zhang , Ernest William Kovacs
发明人： Omayra Padilla De Jesus , Faisal Ahmed Syud , Rong Zhang , Ernest William Kovacs
IPC分类号： C07K1/107 , C07K2/00
CPC分类号： C07K1/13 , A61K51/08 , C07B59/008 , C07K5/0817 , C07K5/1019
摘要： Methods for introducing fluorine atom onto a polypeptide are provided. Also provided are linkers, bioconjugates, and bifunctional compound agents made using the methods, linkers, and bioconjugates. The methods comprise: (i) providing a linker comprising a thiol-reactive terminus and an aldehyde-reactive terminus; (ii) reacting the thiol-reactive terminus of the linker with a polypeptide comprising at least one thiol group or a reactive derivative thereof; and (iii) subsequently reacting the aldehyde-reactive terminus of the linker with a fluorine-substituted aldehyde.
摘要翻译：提供了将氟原子引入到多肽上的方法。还提供了使用方法，接头和生物缀合物制备的接头，生物缀合物和双功能化合物试剂。所述方法包括：（i）提供包含硫醇反应性末端和醛反应性末端的连接体; （ii）使接头的硫醇反应性末端与包含至少一个硫醇基团或其反应性衍生物的多肽反应; 和（iii）随后使接头的醛反应性末端与氟取代的醛反应。

118. 发明申请

US20070197558A1 ANTI-VIRAL COMPOUNDS 有权
标题翻译：反虚构化合物
公开(公告)号：US20070197558A1
公开(公告)日：2007-08-23
申请号：US11613825
申请日：2006-12-20
申请人： David Betebenner , David DeGoey , Clarence Maring , Allan Krueger , Nobuhiko Iwasaki , Todd Rockway , Curt Cooper , David Anderson , Pamela Donner , Brian Green , Dale Kempf , Dachun Liu , Keith McDaniel , Darold Madigan , Christopher Motter , John Pratt , Jason Shanley , Michael Tufano , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami Pilot-Matias , Sherie Masse , Robert Carrick , Wenping He , Liangjun Lu , David Grampovnik
发明人： David Betebenner , David DeGoey , Clarence Maring , Allan Krueger , Nobuhiko Iwasaki , Todd Rockway , Curt Cooper , David Anderson , Pamela Donner , Brian Green , Dale Kempf , Dachun Liu , Keith McDaniel , Darold Madigan , Christopher Motter , John Pratt , Jason Shanley , Michael Tufano , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami Pilot-Matias , Sherie Masse , Robert Carrick , Wenping He , Liangjun Lu , David Grampovnik
IPC分类号： A61K31/519 , C07D498/02 , C07D487/02
CPC分类号： C07D487/04 , C07D471/04 , C07D475/06 , C07D495/04 , C07D513/04
摘要： Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
摘要翻译：公开了有效抑制丙型肝炎病毒（“HCV”）或其他病毒复制的化合物。本发明还涉及包含这些化合物的组合物，这些化合物与其它抗病毒剂或治疗剂的共同配制或共同给药，用于合成这些化合物的方法和中间体，以及使用这些化合物治疗 HCV或其他病毒感染。

119. 发明申请

US20070044758A1 Method and apparatus for controlling throttle during vehicle coasting 有权
标题翻译：车辆滑行期间控制油门的方法和装置
公开(公告)号：US20070044758A1
公开(公告)日：2007-03-01
申请号：US11215150
申请日：2005-08-30
申请人： Rong Zhang
发明人： Rong Zhang
IPC分类号： F02D41/00 , F02D11/10 , G05D1/00 , G06G7/70
CPC分类号： F02D31/002 , F02D9/02 , F02D2011/102 , F02D2200/0404 , F02D2200/602
摘要： A method and system to improve fuel economy of an engine on a vehicle is offered. An electronic throttle control device is commanded to a wide open throttle position during vehicle coast down, thus improving engine breathing and reducing pumping losses, and improving engine efficiency. This includes monitoring operator inputs to: an accelerator device, a braking device, and a cruise control device, and, monitoring throttle position control input from the electronic controller to the electronically controlled throttle mechanism. The electronically controlled throttle mechanism is commanded to a substantially wide-open throttle condition only when the monitored operator inputs to the accelerator device, the braking device, and the cruise control device are each at a null position. A further limitation on the wide-open throttle command includes monitoring other inputs from the electronic controller to the throttle mechanism.
摘要翻译：提供了一种提高车辆发动机燃油经济性的方法和系统。在车辆滑行期间，电子节气门控制装置被命令为大的打开节气门位置，从而改善发动机的呼吸并减少泵送损失，并提高发动机效率。这包括监视操作员输入以加速装置，制动装置和巡航控制装置，以及监视从电子控制器到电子控制的节流机构的节气门位置控制输入。只有当所监视的操作者对加速器装置，制动装置和巡航控制装置的输入各自处于零位置时，电子控制的节气门机构被命令为基本上宽的开启节气门状态。宽开口节气门指令的另一限制包括监视从电子控制器到节气门机构的其它输入。

120. 发明申请

US20050254825A1 System and method for automatic chromatic dispersion compensation 有权
标题翻译：自动色散补偿的系统和方法
公开(公告)号：US20050254825A1
公开(公告)日：2005-11-17
申请号：US10845203
申请日：2004-05-12
申请人： Yu Bai , Rong Zhang
发明人： Yu Bai , Rong Zhang
IPC分类号： H04B10/00 , H04B10/08 , H04B10/155 , H04B10/18
CPC分类号： H04B10/504 , H04B10/0775 , H04B10/25137 , H04B10/505 , H04B10/50577 , H04B2210/077
摘要： An apparatus and method for transmitting a signal for optical network applications with automatic chromatic dispersion compensation. The apparatus includes a first optical transmitter. The first optical transmitter includes a first light source configured to generate a first laser signal in response to a first laser drive signal, a first data modulator configured to receive the first laser signal and a first data drive signal and output a first chirped return-to-zero signal, and a first signal source configured to generate a first non-return-to-zero signal. Additionally, the apparatus includes a first clock and data recovery system, a first data driver, a first adjustment system, and a first control system.
摘要翻译：一种用于发送具有自动色散补偿的光网络应用信号的装置和方法。该装置包括第一光发射器。第一光发射机包括：第一光源，被配置为响应于第一激光驱动信号产生第一激光信号;第一数据调制器，被配置为接收第一激光信号和第一数据驱动信号，并输出第一啁啾返回并且被配置为产生第一非归零信号的第一信号源。此外，该装置包括第一时钟和数据恢复系统，第一数据驱动器，第一调整系统和第一控制系统。

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