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111. 发明公开

EP0155162A3 Carbonate selective membrane and electrode 有权转让
标题翻译：碳酸盐选择性膜和电极
公开(公告)号：EP0155162A3
公开(公告)日：1988-09-21
申请号：EP85301651
申请日：1985-03-11
申请人： TECHNICON INSTRUMENTS CORPORATION (a New York corporation)
发明人： Chapoteau, Eddy , Scott, W James
IPC分类号： G01N27/30
CPC分类号： G01N27/3335
摘要： A carbonate ion selective membrane comprises (a) a polymeric inert support material; (b) a plasticizer effective to solubilize the support material; (c) a quaternary ammonium ion; (d) an ionophore which is preferentially reactive with carbonate ions; and (e) a hydrophobic molecule effective to exclude ions other than carbonate ions. The hydrophobic molecule in the membrane assists in the «binding» of the organic constituents to the matrix, and it repels charged species, i.e. anions and cations, from the solution phase, thereby improving selectivity to the carbonate species which enters the membrane via selective complexation with the ionophore. The quaternary ammonium ion is preferably a C 7 to C 9 quaternary ammonium ion. In this case, the plasticizer is selected to be one effective to maximize the binding of carbonate ions with the C 7 to C 9 quaternary ammonium ions. The invention further provides a carbonate ion selective electrode comprising an internal reference element in electrochemical contact with the membrane described above.

112. 发明公开

EP0202657A3 Isolation fluid control device and water cup 失效转让
标题翻译：隔离液控制装置和水杯
公开(公告)号：EP0202657A3
公开(公告)日：1988-06-01
申请号：EP86106855
申请日：1986-05-20
申请人： TECHNICON INSTRUMENTS CORPORATION (a New York corporation)
发明人： Aoyagi, Keichi
IPC分类号： B01L11/00 , G01N35/08 , G01N01/10
CPC分类号： G01N35/08 , G01N35/1004
摘要： An isolation fluid control device and water cup for use in an automated, random-access, isolation fluid-based, analytical instrument. The cup, in operation, contains two immiscible liquids. The cup is provided with inlet and outlet means, and additionally comprises a liquid level control means and means operable to permit passage of one liquid therethrough to the substantial exclusion of the other liquid.

113. 发明授权

EP0140616B1 Method and apparatus for determining the volume and index of refraction of particles 有权转让
$Method and apparatus for determining the volume and index of refraction of particles$
标题翻译：用于确定颗粒的体积和折射率的方法和装置
公开(公告)号：EP0140616B1
公开(公告)日：1988-03-09
申请号：EP84306942.8
申请日：1984-10-11
申请人： TECHNICON INSTRUMENTS CORPORATION (a New York corporation)
发明人： Tycko, Daniel H.
IPC分类号： G01N21/47
CPC分类号： G01N15/1459 , G01N15/1012 , G01N21/41 , G01N2015/0073 , G01N2015/0238 , G01N2015/1018 , G01N2021/4707

114. 发明公开

EP0140521A3 Specific binding assay 有权转让
标题翻译：具体的绑定测试特殊绑定测试
公开(公告)号：EP0140521A3
公开(公告)日：1988-01-13
申请号：EP84305823
申请日：1984-08-24
申请人： TECHNICON INSTRUMENTS CORPORATION (a New York corporation)
发明人： Fox, John P. , Hedaya, Eddie , Lippman, Violet
IPC分类号： G01N33/542 , G01N33/544 , G01N33/554
CPC分类号： G01N33/554 , G01N33/542 , Y10S435/966 , Y10S435/968 , Y10S436/829
摘要： @ A specific binding assay composition for determining a ligand in a sample, comprises (a) a binding partner for the ligand; (b) a detection system which has at least two components; (c) a selectively accessible vesicle having a surface-incorporated ligand or ligand analog and a first component of the detection system therein; (d) a substance which modifies vesicle accessibility in response to binding of surface-associated ligand or ligand analog and binding partner; and (e) at least one additional component of the detection system which is reactive with the first component to produce a detectable response which is reduced by association of the binding partner and vescile modifying substance with the variably accessible vesicle. A decrease in signal is measured upon reaction as compared to the signal of unreacted vesicles.

115. 发明公开

EP0218097A3 Stabilized aqueous hydrogen peroxide solution 失效转让
标题翻译：稳定的水性过氧化氢溶液
公开(公告)号：EP0218097A3
公开(公告)日：1988-01-07
申请号：EP86112199
申请日：1986-09-03
申请人： TECHNICON INSTRUMENTS CORPORATION (a New York corporation)
发明人： Malin, Michael J. , Sclafani, Louis D.
IPC分类号： C01B15/037
CPC分类号： C01B15/037
摘要： This invention relates to a novel stabilized aqueous hydrogen peroxide solution which comprises hydrogen peroxide in admixture with an aromatic polysulfonic acid, or a salt thereof.

116. 发明公开

EP0248514A1 System and method for dispensing metered quantities of a fluid 失效转让
标题翻译：系统和Verfahren zur Abgabe von abgemessenenFlüssigkeitsmengen。
公开(公告)号：EP0248514A1
公开(公告)日：1987-12-09
申请号：EP87303044.9
申请日：1987-04-08
申请人： TECHNICON INSTRUMENTS CORPORATION(a Delaware corporation)
发明人： Uffenheimer Kenneth F. , Negersmith, Kent M.
IPC分类号： G01F11/08
CPC分类号： G01F11/08
摘要： A fluid delivery system (10) and method for dispensing precisely metered quantities of a fluid, comprising fluid supply means (16); pump means (22); a conduit (14) interconnecting said fluid supply means and pump means; a first valve (18) in said conduit positioned intermediate said fluid supply means and pump means; a nozzle (28) for discharging said fluid from said system; a further conduit (24) connecting said nozzle with said pump means and with said conduit; a second valve (26) in said further conduit; means (44) for selectively applying a vacuum and a superatmospheric pressure to said pump means; and control means (50) operatively interconnecting said first and second valves and said selective pressure applying means for aspirating predetermined quantities of fluid from said fluid supply means through said 'conduit to said pump means and thereafter conveying said quantities of fluid from said pump means to said nozzle, the system being so arranged as to cause formation of a fluid flow-occluding air bubble in said nozzle upon termination of discharge of fluid from said nozzle so as to inhibit discharge of residual droplets of said fluid from said nozzle.
摘要翻译：一种用于分配精确计量的流体的流体输送系统（10）和方法，包括流体供应装置（16）; 泵装置（22）; 将所述流体供应装置和泵装置相互连接的导管（14）所述管道中的位于所述流体供应装置和泵装置之间的第一阀门（18）用于从所述系统排出所述流体的喷嘴（28）; 连接所述喷嘴与所述泵装置和所述导管的另一管道（24）; 所述另一导管中的第二阀（26）用于选择性地向所述泵装置施加真空和超大气压的装置（44）; 以及控制装置（50），其可操作地将所述第一和第二阀和所述选通压力施加装置相互连接，用于通过所述导管从所述流体供应装置抽吸预定量的流体到所述泵装置，然后将所述数量的流体从所述泵装置输送到所述喷嘴，所述系统被布置成在从所述喷嘴排出流体终止时在所述喷嘴中形成流体阻塞气泡，以便抑制所述流体从所述喷嘴的残留液滴的排放。

117. 发明授权

EP0117674B1 Radiation energy integrating sphere 有权转让
标题翻译：辐射能量积分球
公开(公告)号：EP0117674B1
公开(公告)日：1987-09-23
申请号：EP84300866.5
申请日：1984-02-10
申请人： TECHNICON INSTRUMENTS CORPORATION (a New York corporation)
发明人： Stark, Edward W.
IPC分类号： G01N21/47
CPC分类号： G01N21/474 , G01N2201/065

118. 发明授权

EP0070623B1 Reaction cuvette 有权转让
标题翻译：反应CUVETTE
公开(公告)号：EP0070623B1
公开(公告)日：1986-12-17
申请号：EP82303211.5
申请日：1982-06-21
申请人： TECHNICON INSTRUMENTS CORPORATION (a New York corporation)
发明人： Cassasay, Michael M. , Diebler, Herman G. , Svenjak, Dario , Uffenheimer, Kenneth F.
IPC分类号： G01N21/03 , G01N35/00
CPC分类号： G01N21/253

119. 发明公开

EP0202659A2 Liquid level adjusting and filtering device 失效转让
标题翻译：装置，用于调整对象和用于过滤液体。
公开(公告)号：EP0202659A2
公开(公告)日：1986-11-26
申请号：EP86106858.3
申请日：1986-05-20
申请人： TECHNICON INSTRUMENTS CORPORATION(a Delaware corporation)
发明人： Cassaday, Michael M. , Herron, Rand , Uffenheimer, Kenneth F. , Smith, John L.
IPC分类号： B01L3/14 , G01N1/34 , G01N33/48 , G01N35/00
CPC分类号： G01N33/491
摘要： New and improved, liquid level adjusting and filtering device is provided, and is operable upon insertion into a container to automatically adjust the level of a liquid as contained in the container to a predetermined, precisely repeatable location, and to filterthethusly level-adjusted liquid. The device is particularly adapted for use in conjunction with test tube-like devices, in the nature of those marketed under the trademark "Vacutainer" by the Becton Dickinson Company of East Rutherford, New Jersey, containing whole blood samples which have been separated as by centrifugation into respective blood cell, buffy and blood serum layers; and is operable in that context to present blood serum samples to automated sample analysis systems at the same predetermined and precisely repeatable location relative to the aspirating probe means of such systems.

120. 发明公开

EP0202658A1 Zero dead volume connector 失效转让
标题翻译：空Restvolumenverbinder。
公开(公告)号：EP0202658A1
公开(公告)日：1986-11-26
申请号：EP86106856.7
申请日：1986-05-20
申请人： TECHNICON INSTRUMENTS CORPORATION(a Delaware corporation)
发明人： Cassaday, Michael M. , Castellani, Leon , Saros, Stephen
IPC分类号： F16L37/00 , F16L47/00 , A61M5/00 , G01N35/00
CPC分类号： F16L47/00
摘要： New and improved connector (10) is provided forthe zero dead volume connection of separate, like diameter flexible tubing lengths (16,18) by direct tubing length end abutment and connection under controlled conditions. The connector (10) is particularly adapted for use with tubing lengths (16,18) of fluorocarbon or like materials in contemporary biomedical sample liquid analysis systems which utilize an immiscible isolation liquid or "oil" to minimize sample liquid carryover and maximize the accuracy of sample liquid analysis results.

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