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101. 发明申请

US20130190810A1 CLOSURE DEVICE 有权
标题翻译：封闭装置
公开(公告)号：US20130190810A1
公开(公告)日：2013-07-25
申请号：US13791829
申请日：2013-03-08
申请人： Wouter E. Roorda , Kelly J. McCrystle , Ian J. Clark , Laveille K. Voss , Ni Ding
发明人： Wouter E. Roorda , Kelly J. McCrystle , Ian J. Clark , Laveille K. Voss , Ni Ding
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2017/00654 , A61B2017/00659 , A61B2017/00986 , A61B2017/00991 , A61B2090/0811
摘要： A device for closing an opening in a wall of a body lumen includes a closure element with a first flange and a second flange. Both the first flange and the second flange may have a delivery cross-sectional dimension and a deployed cross-sectional dimension. The device for closing an opening further includes a first coupler element disposed on the first flange and a second coupler element disposed on the second flange, the first and second coupler elements cooperating to couple the first flange to the second flange.
摘要翻译：用于关闭体腔内的开口的装置包括具有第一凸缘和第二凸缘的闭合元件。第一凸缘和第二凸缘都可以具有输送横截面尺寸和展开的横截面尺寸。用于关闭开口的装置还包括设置在第一凸缘上的第一耦合器元件和设置在第二凸缘上的第二耦合器元件，第一和第二耦合器元件协作以将第一凸缘耦合到第二凸缘。

102. 发明申请

US20130041129A1 Controlling Moisture In And Plasticization Of Bioresorbable Polymer For Melt Processing 有权
标题翻译：控制用于熔体加工的生物可吸收聚合物的水分和塑化
公开(公告)号：US20130041129A1
公开(公告)日：2013-02-14
申请号：US13207656
申请日：2011-08-11
申请人： Bethany Steichen , Stephen D. Pacetti , Manish Gada , Thierry Glauser , Lothar W. Kleiner , Yunbing Wang , James P. Oberhauser , Ni Ding
发明人： Bethany Steichen , Stephen D. Pacetti , Manish Gada , Thierry Glauser , Lothar W. Kleiner , Yunbing Wang , James P. Oberhauser , Ni Ding
IPC分类号： A61L31/06 , C08G63/90 , G05B1/00
CPC分类号： B29C47/0078 , B29B13/06 , B29B13/065 , B29C47/0014 , B29C47/0021 , B29C47/0023 , B29C47/1018 , B29C47/1072 , B29C47/76 , B29C47/92 , B29C2947/922 , B29C2947/92228 , B29C2947/92342 , B29C2947/92695 , B29C2947/92704 , B29C2947/92723 , B29K2995/006
摘要： Methods and systems for controlling the moisture content of biodegradable and bioresorbable polymer resin during extrusion above a lower limit that allows for plasticization of the polymer resin melt and below an upper limit to reduce or prevent molecular weight loss are disclosed. Methods are further disclosed involving plasticization of a polymer resin for feeding into an extruder with carbon dioxide and freon.
摘要翻译：公开了用于在挤出之前控制可生物降解和生物可再吸收的聚合物树脂的含水量的方法和系统，其允许聚合物树脂熔体增塑并低于上限以降低或防止分子量损失。进一步公开的方法涉及用二氧化碳和氟利昂进料到挤出机中的聚合物树脂的增塑。

103. 发明申请

US20120328770A1 Methods For Modulating The Release Rate Of A Drug-Coated Stent 失效
标题翻译：用于调节药物包被支架释放速率的方法
公开(公告)号：US20120328770A1
公开(公告)日：2012-12-27
申请号：US13605795
申请日：2012-09-06
申请人： Shaw Ling Hsu , Ni Ding , Yiwen Tang , Fuh-Wei Tang , Lothar Walter Kleiner , Syed Faiyaz Ahmed Hossainy
发明人： Shaw Ling Hsu , Ni Ding , Yiwen Tang , Fuh-Wei Tang , Lothar Walter Kleiner , Syed Faiyaz Ahmed Hossainy
IPC分类号： B05D7/00
CPC分类号： A61L31/10 , A61F2240/001 , A61F2250/0056 , A61F2250/0068 , A61L31/16 , A61L2300/416 , A61L2300/60 , C08L33/10 , C08L27/16 , C08L27/20 , C08L29/04
摘要： Methods for modulating the release rate of a drug coated stent are disclosed.
摘要翻译：公开了调节药物涂层支架释放速率的方法。

104. 发明授权

US08293318B1 Methods for modulating the release rate of a drug-coated stent 有权
标题翻译：调节药物涂层支架释放速率的方法
公开(公告)号：US08293318B1
公开(公告)日：2012-10-23
申请号：US11847222
申请日：2007-08-29
申请人： Shaw Ling Hsu , Ni Ding , Yiwen Tang , Fuh-Wei Tang , Lothar Walter Kleiner , Syed Faiyaz Ahmed Hossainy
发明人： Shaw Ling Hsu , Ni Ding , Yiwen Tang , Fuh-Wei Tang , Lothar Walter Kleiner , Syed Faiyaz Ahmed Hossainy
IPC分类号： B05D3/02 , A61L33/00 , A61F2/06
CPC分类号： A61L31/10 , A61F2240/001 , A61F2250/0056 , A61F2250/0068 , A61L31/16 , A61L2300/416 , A61L2300/60 , C08L33/10 , C08L27/16 , C08L27/20 , C08L29/04
摘要： Methods for modulating the release rate of a drug coated stent are disclosed.
摘要翻译：公开了调节药物涂层支架释放速率的方法。

105. 发明授权

US08007858B2 System and method for coating implantable devices 有权
标题翻译：可植入装置涂层的系统和方法
公开(公告)号：US08007858B2
公开(公告)日：2011-08-30
申请号：US12363538
申请日：2009-01-30
申请人： Stephen D. Pacetti , Wouter E. Roorda , Ni Ding
发明人： Stephen D. Pacetti , Wouter E. Roorda , Ni Ding
IPC分类号： A61L33/00
CPC分类号： B05D3/0466 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61L2420/02 , B05D3/0473 , B05D3/048 , Y10T428/1393 , Y10T428/31507 , Y10T428/31551 , Y10T428/31725 , Y10T428/31786 , Y10T428/31855
摘要： A method and system of coating an implantable device, such as a stent, are provided.
摘要翻译：提供涂覆可植入装置（例如支架）的方法和系统。

106. 发明授权

US07985441B1 Purification of polymers for coating applications 有权
标题翻译：用于涂料应用的聚合物的纯化
公开(公告)号：US07985441B1
公开(公告)日：2011-07-26
申请号：US11418697
申请日：2006-05-04
申请人： Yiwen Tang , Stephen D. Pacetti , Qing Lin , Ni Ding
发明人： Yiwen Tang , Stephen D. Pacetti , Qing Lin , Ni Ding
IPC分类号： B05D3/00 , C08F6/28
CPC分类号： C08F6/005 , A61L31/10 , A61L2420/02 , C08L27/20 , C08L27/16
摘要： Various embodiments of methods and devices for coating stents are described herein. Among these embodiments are methods of manufacturing an implantable medical device by purifying a polymer with a fluid capable of swelling the polymer, and subsequently coating a device with the purified polymer or fabricating a device from the purified polymer. A preferred polymer is poly(vinylidene fluoride-co-hexafluoropropylene).
摘要翻译：本文描述了用于涂覆支架的方法和装置的各种实施例。在这些实施方案中，通过用能够使聚合物膨胀的流体纯化聚合物，随后用纯化的聚合物涂覆装置或从纯化的聚合物制造装置来制造可植入医疗装置的方法。优选的聚合物是聚（偏二氟乙烯 - 共 - 六氟丙烯）。

107. 发明授权

US07955615B2 Polycationic peptide coatings and methods of coating implantable medical devices 有权
公开(公告)号：US07955615B2
公开(公告)日：2011-06-07
申请号：US11212376
申请日：2005-08-26
申请人： Stephen D. Pacetti , Eugene T. Michal , Syed F. A. Hossainy , Ni Ding , Wouter E. Roorda
发明人： Stephen D. Pacetti , Eugene T. Michal , Syed F. A. Hossainy , Ni Ding , Wouter E. Roorda
IPC分类号： A61F2/04
CPC分类号： A61K31/727 , A61K31/728 , A61K31/737 , A61L31/10 , C08L89/00
摘要： Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed.

108. 发明授权

US07875286B2 Polycationic peptide coatings and methods of coating implantable medical devices 有权
标题翻译：聚阳离子肽涂层和涂覆可植入医疗器械的方法
公开(公告)号：US07875286B2
公开(公告)日：2011-01-25
申请号：US11213290
申请日：2005-08-26
申请人： Stephen D. Pacetti , Eugene T. Michal , Syed F. A. Hossainy , Ni Ding , Wouter E. Roorda
发明人： Stephen D. Pacetti , Eugene T. Michal , Syed F. A. Hossainy , Ni Ding , Wouter E. Roorda
IPC分类号： A61F2/02
CPC分类号： A61K31/727 , A61K31/728 , A61K31/737 , A61L31/10 , C08L89/00
摘要： Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed.
摘要翻译：公开了包括聚阳离子肽如L-精氨酸的医疗器械用涂层和制造涂层的方法。

109. 发明授权

US07815561B2 Brachytherapy applicator 有权
标题翻译：近距离放疗
公开(公告)号：US07815561B2
公开(公告)日：2010-10-19
申请号：US10742445
申请日：2003-12-19
申请人： Michael R. Forman , Darius Francescatti , Ni Ding
发明人： Michael R. Forman , Darius Francescatti , Ni Ding
IPC分类号： A61N5/00
CPC分类号： A61N5/1015 , A61N5/1027
摘要： A breast brachytherapy applicator providing a stable semi permanent/permanent in dwelling platform that is configured to replicate anatomically the excised cancer bed and allows for a more precise anatomically correct delivery of limited field radiation treatment. This device may be used to reconstitute a resected tissue space to its pre-operative size and shape to 1) facilitate the accurate and precise delivery of adjunctive breast brachytherapy following breast cancer surgery and 2) prevent/decrease post-operative deformity as a result of surgical resection, whether for benign or malignant disease, and in particular after radiation treatment of malignant disease in the post lumpectomy patient.
摘要翻译：一种乳房近距离放射治疗仪，其提供稳定的半永久/永久性住宅平台，其被配置为在解剖学上复制切除的癌床，并允许更精确的解剖学上正确的有限的放射治疗递送。该装置可用于将切除的组织空间重建为其手术前的大小和形状，以便于1）促进乳腺癌手术后辅助乳房近距离放射治疗的准确和精确的传递，以及2）由于以下原因：预防/减少术后畸形手术切除，无论是良性还是恶性疾病，特别是放射治疗乳房肿瘤切除术后患者的恶性疾病。

110. 发明授权

US07803406B2 Polycationic peptide coatings and methods of coating implantable medical devices 有权
标题翻译：聚阳离子肽涂层和涂覆可植入医疗器械的方法
公开(公告)号：US07803406B2
公开(公告)日：2010-09-28
申请号：US11213288
申请日：2005-08-26
申请人： Stephen D. Pacetti , Eugene T. Michal , Syed F. A. Hossainy , Ni Ding , Wouter E. Roorda
发明人： Stephen D. Pacetti , Eugene T. Michal , Syed F. A. Hossainy , Ni Ding , Wouter E. Roorda
IPC分类号： A61K9/50
CPC分类号： A61K31/727 , A61K31/728 , A61K31/737 , A61L31/10 , C08L89/00
摘要： Methods of forming coatings comprising a polycationic peptide for medical devices are disclosed. Also disclosed is a coating comprising a polycationic peptide.
摘要翻译：公开了形成包含用于医疗装置的聚阳离子肽的涂层的方法。还公开了包含聚阳离子肽的涂层。

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