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    • 104. 发明申请
    • System and Method for Laser Imaging and Ablation of Cancer Cells Using Fluorescence
    • 使用荧光的激光成像和癌细胞消融的系统和方法
    • US20140187879A1
    • 2014-07-03
    • US14097337
    • 2013-12-05
    • Fred WoodDmitry YavidJoe ZottRon Goldman
    • Fred WoodDmitry YavidJoe ZottRon Goldman
    • A61B5/00A61B18/20
    • A61B5/0071A61B5/0077A61B5/742A61B18/20A61B2018/00577
    • A fluorescence imaging device detects fluorescence in parts of the visible and invisible spectrum, and projects the fluorescence image directly on the human body, as well as on a monitor, with improved sensitivity, video frame rate and depth of focus, and enhanced capabilities of detecting distribution and properties of multiple fluorophores. Direct projection of three-dimensional visible representations of florescence on three-dimensional body areas advantageously permits view of it during surgical procedures, including during cancer removal, reconstructive surgery and wound care, etc. A NIR laser and a human visible laser (HVL) are aligned coaxially and scanned over the operating field of view. When the NIR laser passes over the area where the florescent dye is present, it energizes the dye which emits at a shifted NIR frequency detected by a photo diode. The HVL is turned on when emission is detected, providing visual indication of those positions.
    • 荧光成像装置在可见光和不可见光谱的一部分中检测荧光,并将荧光图像直接投射在人体以及显示器上,具有改进的灵敏度,视频帧率和焦深,以及增强的检测能力 分布和多种荧光团的性质。 荧光三维可视表示直接投影在三维身体区域有利于允许在手术过程中观察它,包括在癌症消除,重建手术和伤口护理等期间。近红外激光和人类可见激光(HVL)是 同轴对齐并在操作视野上进行扫描。 当NIR激光通过存在荧光染料的区域时,它激发以由光电二极管检测到的移位的NIR频率发射的染料。 当检测到发射时,HVL被接通,提供这些位置的视觉指示。