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101. 发明申请

US20130245233A1 Multispecific Molecules 审中-公开
标题翻译：多特异性分子
公开(公告)号：US20130245233A1
公开(公告)日：2013-09-19
申请号：US13988802
申请日：2011-11-22
申请人： Ming Lei , Jing Li , Li Zhou , Zhenping Zhu
发明人： Ming Lei , Jing Li , Li Zhou , Zhenping Zhu
IPC分类号： C07K16/46
CPC分类号： C07K16/468 , C07K16/00 , C07K16/2863 , C07K16/32 , C07K2317/31 , C07K2317/53 , C07K2317/60 , C07K2317/64
摘要： The present invention is directed to multi-specific/multivalent molecules of novel formats. The molecules with the formats of the present invention have desired yield and thermostability. The present invention also includes methods of producing and using the molecules described herein.
摘要翻译：本发明涉及新型的多特异性/多价分子。具有本发明形式的分子具有期望的产率和热稳定性。本发明还包括生产和使用本文所述分子的方法。

102. 发明申请

US20130234718A1 MULTI-ARRAY LATEROLOG TOOLS AND METHODS WITH DIFFERENTIAL VOLTAGE MEASUREMENTS 有权
标题翻译：具有差分电压测量的多阵列流变仪工具及方法
公开(公告)号：US20130234718A1
公开(公告)日：2013-09-12
申请号：US13884034
申请日：2011-11-02
申请人： Shanjun Li , Luis E. San Martin , Michael S. Bittar , Jing Li
发明人： Shanjun Li , Luis E. San Martin , Michael S. Bittar , Jing Li
IPC分类号： G01V3/20
CPC分类号： G01V3/20 , E21B47/102 , E21B49/00 , G01V3/24 , G01V3/28 , G01V2200/16
摘要： Multi-array laterolog tool systems and methods acquire a set of array measurements sufficient to provide laterolog tool measurements of differing array sizes. Such systems and method offer multiple depths of investigation while offering greater measurement stability in borehole environments having high resistivity contrasts. In at least some system embodiments, a wireline or LWD tool body has a center electrode positioned between multiple pairs of guard electrodes and a pair of return electrodes. The tool's electronics provide a current from the center electrode to the pair of return electrodes and currents from each pair of guard electrodes to the pair of return electrodes. Each of the currents may be distinguishable by frequency or distinguishable by some other means. This novel arrangement of currents provides a complete set of measurements that enables one tool to simultaneously emulate a whole range of laterolog tools.
摘要翻译：多阵列后验工具系统和方法获取足够的阵列测量集，以提供不同阵列大小的后者工具测量。这种系统和方法提供多个调查深度，同时在具有高电阻率对比度的钻孔环境中提供更大的测量稳定性。在至少一些系统实施例中，有线或LWD工具主体具有位于多对保护电极和一对返回电极之间的中心电极。工具的电子器件提供从中心电极到一对返回电极的电流以及从每对保护电极到一对返回电极的电流。每个电流可以通过频率区分或通过某种其他方式可区分。这种新颖的电流布置提供了一整套测量，使一个工具能够同时模拟一整套后期工具。

103. 发明授权

US08513218B2 Derivatives of 1-amino-2-cyclopropylethylboronic acid 有权
公开(公告)号：US08513218B2
公开(公告)日：2013-08-20
申请号：US13075306
申请日：2011-03-30
申请人： Paul E. Fleming , Jing Li
发明人： Paul E. Fleming , Jing Li
IPC分类号： A61K31/69 , C07F5/02 , C07F5/04
CPC分类号： C07F5/04 , C07F5/025
摘要： The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.

104. 发明授权

US08507647B2 Antibacterial agents for the treatment of gram positive infections 有权
标题翻译：用于治疗革兰氏阳性感染的抗菌剂
公开(公告)号：US08507647B2
公开(公告)日：2013-08-13
申请号：US12641465
申请日：2009-12-18
申请人： Chester A. Metcalf, III , Jing Li , Andre Lee Pearson
发明人： Chester A. Metcalf, III , Jing Li , Andre Lee Pearson
IPC分类号： C07K11/02
CPC分类号： C07K7/54 , A61K38/00 , C07K7/08
摘要： The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the invention are particularly useful against a variety of bacteria, including resistant strains. The compounds are useful as antibacterial agents against Clostridium difficile.
摘要翻译：本发明涉及新型脂肽化合物，这些化合物的药物组合物和使用这些化合物作为抗菌化合物的方法。本发明的化合物特别适用于各种细菌，包括抗性菌株。这些化合物可用作针对艰难梭菌的抗菌剂。

105. 发明授权

US08470993B2 Nucleic acid encoding antibody to human IL-22 有权
标题翻译：编码针对人IL-22的抗体的核酸
公开(公告)号：US08470993B2
公开(公告)日：2013-06-25
申请号：US13477717
申请日：2012-05-22
申请人： Davinder S. Gill , Jing Li , Geertruida M. Veldman , Lynette A. Fouser , Viia Valge-Archer , David C. Lowe , Caroline S. Russell , Suzanne E. Cohen , Albert G. Thom , Ralph R. Minter
发明人： Davinder S. Gill , Jing Li , Geertruida M. Veldman , Lynette A. Fouser , Viia Valge-Archer , David C. Lowe , Caroline S. Russell , Suzanne E. Cohen , Albert G. Thom , Ralph R. Minter
IPC分类号： C12N5/10 , C12N15/13 , C12N15/63
CPC分类号： C07K16/244 , C07K2317/21 , C07K2317/33 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-22 (IL-22). The antibodies can act as antagonists of IL-22 activity, thereby modulating immune responses in general, and those mediated by IL-22 in particular. The disclosed compositions and methods may be used for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, septic shock, infectious disorders, transplant rejection, cancer, and other immune system disorders.
摘要翻译：本申请提供特异性结合人白细胞介素-22（IL-22）的人抗体及其抗原结合片段。抗体可以作为IL-22活性的拮抗剂，从而调节一般的免疫应答，特别是由IL-22介导的那些。所公开的组合物和方法可用于例如诊断，治疗或预防炎性疾病，自身免疫性疾病，过敏，败血性休克，感染性疾病，移植排斥，癌症和其他免疫系统疾病。

106. 发明授权

US08356095B2 Method and apparatus for transferring context information on web server 失效
标题翻译：用于在Web服务器上传送上下文信息的方法和装置
公开(公告)号：US08356095B2
公开(公告)日：2013-01-15
申请号：US12749031
申请日：2010-03-29
申请人： Bao Hua Cao , Jing Li , Jian Wang , Li Wang
发明人： Bao Hua Cao , Jing Li , Jian Wang , Li Wang
IPC分类号： G06F15/173 , G06F15/16 , G06G15/16
CPC分类号： G06F9/54 , H04L67/02
摘要： A method for transferring context information on a web server that contains a context pool. The method includes: in response to the web server receiving a message, obtaining context information from the message, generating a unique identifier according to a thread for processing the message, associating the context information with the generated unique identifier, and storing the context information and the associated unique identifier in context pool of web server correlatively. In response to a web server obtaining the context information, generating an identifier according to a thread that is executed currently in the web server, and extracting context information for which an associated unique identifier is matched with the generated identifier from the context pool.
摘要翻译：一种用于在包含上下文池的Web服务器上传送上下文信息的方法。该方法包括：响应于web服务器接收消息，从消息获取上下文信息，根据用于处理消息的线程生成唯一标识符，将上下文信息与生成的唯一标识符相关联，并存储上下文信息，以及 Web服务器上下文池中相关联的唯一标识符相关。响应于Web服务器获得上下文信息，根据当前在web服务器中执行的线程生成标识符，并从上下文池中提取相关联的唯一标识符与生成的标识符匹配的上下文信息。

107. 发明申请

US20130007588A1 SYSTEMS AND METHODS FOR GLOBALIZING WEB APPLICATIONS 审中-公开
标题翻译：用于全球化网络应用的系统和方法
公开(公告)号：US20130007588A1
公开(公告)日：2013-01-03
申请号：US13173388
申请日：2011-06-30
申请人： Liang Guo , Jing Li , CongPeng Ma , Wanjun Wang , Xuqin Zhao
发明人： Liang Guo , Jing Li , CongPeng Ma , Wanjun Wang , Xuqin Zhao
IPC分类号： G06F17/00
CPC分类号： G06F11/3688
摘要： Described are a system and method for testing a software application. Elements of a web document under test loaded in a web browser are identified. The elements are output to a plurality of string processors. The string processors determine one or more accessible strings of text and locale-sensitive information from the elements. The accessible strings are validated to determine whether the strings are at least one of correctly pseudo-translated and properly formatted.
摘要翻译：描述了用于测试软件应用程序的系统和方法。识别在web浏览器中加载的被测试的web文档的元素。这些元素被输出到多个串处理器。字符串处理器从元素中确定一个或多个可访问的文本和区域设置敏感信息字符串。可访问的字符串被验证以确定字符串是否是正确的伪翻译和正确格式化中的至少一个。

108. 发明申请

US20130005033A1 ANTIBODIES TO HUMAN IL-22 有权
标题翻译：人类IL-22的抗体
公开(公告)号：US20130005033A1
公开(公告)日：2013-01-03
申请号：US13477717
申请日：2012-05-22
申请人： Davinder S. Gill , Jing Li , Geertruida M. Veldman , Lynette A. Fouser , Viia Valge-Archer , David C. Lowe , Caroline S. Russell , Suzanne E. Cohen , Albert G. Thom , Ralf R. Minter
发明人： Davinder S. Gill , Jing Li , Geertruida M. Veldman , Lynette A. Fouser , Viia Valge-Archer , David C. Lowe , Caroline S. Russell , Suzanne E. Cohen , Albert G. Thom , Ralf R. Minter
IPC分类号： C12N15/13 , C12N1/21 , C12N1/19 , C12N15/63 , C12N5/10
CPC分类号： C07K16/244 , C07K2317/21 , C07K2317/33 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-22 (IL-22). The antibodies can act as antagonists of IL-22 activity, thereby modulating immune responses in general, and those mediated by IL-22 in particular. The disclosed compositions and methods may be used for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, septic shock, infectious disorders, transplant rejection, cancer, and other immune system disorders.
摘要翻译：本申请提供特异性结合人白细胞介素-22（IL-22）的人抗体及其抗原结合片段。抗体可以作为IL-22活性的拮抗剂，从而调节一般的免疫应答，特别是由IL-22介导的那些。所公开的组合物和方法可用于例如诊断，治疗或预防炎性疾病，自身免疫性疾病，过敏，败血性休克，感染性疾病，移植排斥，癌症和其他免疫系统疾病。

109. 发明申请

US20120320877A1 Method, System and Base Station Subsystem for Realizing Handover in Local Switch 有权
标题翻译：在本地交换机中实现切换的方法，系统和基站子系统
公开(公告)号：US20120320877A1
公开(公告)日：2012-12-20
申请号：US13581335
申请日：2011-04-15
申请人： Jing Li , Xinhui Wang
发明人： Jing Li , Xinhui Wang
IPC分类号： H04W36/00
CPC分类号： H04W36/02 , H04W8/082 , H04W36/10
摘要： The present invention provides a method for implementing a handover in a local switch, and the method comprises: when one party Mobile Station of a call implementing a local switch mode performs a Base Station Subsystem handover, the Base Station Subsystem handover transmits uplink speech data of the Mobile Station which does not need to perform the handover on a local switch link of the Base Station Subsystem and a link between the Base Station Subsystem and a Media Gateway simultaneously. A Base Station Subsystem implementing a handover in a local switch is also provided by the present invention. The present invention can efficiently avoid the speech loss of the Mobile Station performing the handover during the handover, and guarantees that the Mobile Station which needs to perform the handover can receive the speech data of the other party user no matter the Mobile Station is in the original BSS or the target BSS, thus maintaining the call between the two Mobile Stations efficiently.
摘要翻译：本发明提供一种在本地交换机中实现切换的方法，所述方法包括：当实现本地交换模式的呼叫的一方移动台执行基站子系统切换时，基站子系统切换发送上行语音数据不需要在基站子系统的本地交换机链路上执行切换的移动台和基站子系统与媒体网关之间的链路同时进行。本发明还提供了实现本地交换机切换的基站子系统。本发明可以有效地避免在切换期间执行切换的移动台的语音丢失，并且保证需要执行切换的移动台可以接收对方用户的语音数据，无论移动台处于原始BSS或目标BSS，从而有效地保持两个移动台之间的呼叫。

110. 发明授权

US08321517B2 Method and system for processing emails 失效
标题翻译：处理电子邮件的方法和系统
公开(公告)号：US08321517B2
公开(公告)日：2012-11-27
申请号：US12771102
申请日：2010-04-30
申请人： Jing Li , Lin Xie , Shi Jia Zhang , Xiao Jin Zhao
发明人： Jing Li , Lin Xie , Shi Jia Zhang , Xiao Jin Zhao
IPC分类号： G06F15/16
CPC分类号： H04L51/28 , G06Q10/107 , H04L51/14 , H04L51/30
摘要： The present invention provides a method and system for processing emails. The method comprising: receiving a correction request including an identifier of an original email and an incorrect recipient; in response to the correction request, creating a correction record including the identifier of the original email and the incorrect recipient; in response to receiving relevant emails of the original email, determining whether recipients of the relevant emails include the incorrect recipient; and in response to determining that recipients of the relevant emails include the incorrect recipient, processing the relevant emails based on the correction record.
摘要翻译：本发明提供一种处理电子邮件的方法和系统。该方法包括：接收包括原始电子邮件的标识符和不正确接收者的校正请求; 响应于所述校正请求，创建包括原始电子邮件的标识符和不正确接收者的校正记录; 响应收到原始电子邮件的相关电子邮件，确定相关电子邮件的收件人是否包含错误的收件人; 并且响应于确定相关电子邮件的收件人包括不正确的接收者，根据修正记录处理相关电子邮件。

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