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101. 发明授权

EP1648536B1 A SYSTEM FOR PERFORMING PERITONEAL DIALYSIS 有权
标题翻译：一种进行腹膜透析的系统
公开(公告)号：EP1648536B1
公开(公告)日：2011-05-18
申请号：EP04738120.7
申请日：2004-08-02
申请人： DEBIOTECH S.A.
发明人： NEFTEL, Frédéric , JUNOD, Florent , VECTEN, Didier, c/o DEBIOTECH SA
IPC分类号： A61M1/28 , F04B43/12
CPC分类号： A61M1/28 , A61M1/281 , A61M5/44 , A61M2205/12 , A61M2205/128 , F04B43/1253 , Y10T137/87249
摘要： The invention concerns a system and a method of use of said system for performing fluid administration on a patient, the system comprising: -a liquid pump (1), - a liquid distribution system (2) connected to said pump (1) in such a way that liquid can flow from the liquid distribution system (2) to the pump (1) and vice versa, - liquid supply means (3) for supplying liquid to a patient (4) via said liquid distribution system (2) and said pump (1), - a patient conduit (5) adapted for connecting said liquid distribution system (2) to a patient (4), the system being characterized by the fact that said liquid distribution system (2) comprises two distinct hub chambers (7,8), the first hub chamber (7) including at least one liquid supply port with dedicated valve means (9), one patient port with dedicated valve means (10) and one pump inlet (26), the second hub chamber (8) including at least, one patient port (18) or warmer port (16) with dedicated valve means and one pump outlet (27), said system furthermore comprising control means arranged to close said patient port (10) of the first hub chamber (7) when said liquid supply port (9) is open and vice versa.
摘要翻译：本发明涉及一种使用所述系统对患者进行流体给药的系统和方法，所述系统包括： - 液体泵（1）， - 与所述泵（1）连接的液体分配系统（2）液体可以从液体分配系统（2）流动到泵（1）并且反之亦然的方式， - 液体供应装置（3），用于经由所述液体分配系统（2）向患者（4）供应液体并且所述泵（1），适于将所述液体分配系统（2）连接到患者（4）的患者导管（5），所述系统的特征在于所述液体分配系统（2）包括两个不同的毂室（7），所述第一毂室包括具有专用阀装置（9）的至少一个液体供应端口，具有专用阀装置（10）和一个泵入口（26）的一个患者端口，所述第二毂室（7,8） 8）包括具有专用阀装置和一个泵出口（27）的至少一个患者端口（18）或加热端口（16），所述系统还包括控制装置，所述控制装置被布置成当所述液体供应端口（9）打开时关闭所述第一毂室（7）的所述患者端口（10），反之亦然。

102. 发明授权

EP1924300B1 POROUS COATING LOADED WITH A LIQUID OR A SOLID SUBSTANCE 有权
标题翻译：多孔结构，液体或固体物质受压涂料
公开(公告)号：EP1924300B1
公开(公告)日：2010-05-26
申请号：EP06809320.2
申请日：2006-09-15
申请人： DEBIOTECH S.A. , Axis Biodental S.A.
发明人： HOFMANN, Heinrich , NEFTEL, Frédéric , PIVETEAU, Laurent-Dominique
IPC分类号： A61L27/28 , A61K31/08
CPC分类号： A61L27/28 , A61L27/54 , A61L27/56 , A61L31/08 , A61L31/146 , A61L31/16 , A61L2300/00 , Y10T428/249978

103. 发明授权

EP2026853B1 ANISOTROPIC NANOPOROUS COATINGS FOR MEDICAL IMPLANTS 有权
标题翻译：用于医学植入物的各向异性纳米多孔涂层
公开(公告)号：EP2026853B1
公开(公告)日：2009-09-09
申请号：EP07845258.8
申请日：2007-05-16
申请人： DEBIOTECH S.A.
发明人： PIVETEAU, Laurent-Dominique , HOFMANN, Heinrich , NEFTEL, Frédéric
IPC分类号： A61L27/28 , A61L27/30 , A61L27/54 , A61L31/08 , A61F2/82 , A61C8/00
CPC分类号： A61M31/002 , A61B17/68 , A61C8/0004 , A61C8/0013 , A61C8/0015 , A61C2008/0046 , A61F2/82 , A61F2240/001 , A61F2250/0068 , A61L27/28 , A61L27/56 , A61L31/08 , A61L31/146 , A61L2400/12 , Y10T428/24942 , Y10T428/249979
摘要： The present invention relates to a process for fabricating a porous coatings with controlled structure in the micro and nano-size domain. In particular, but not exclusively, it relates to a process for fabricating coatings with an anisotropic pore size distribution and to coatings obtained using such coatings. It describes in particular the use of ink-jet method to deposit in a controlled way such coatings. It also relates to porous coatings with controlled structure in the micro and nano-size domain. The coating has a thickness between 10 nanometers and 10 millimeters and its porosity is created in such a way that the pore size distribution is anisotropic. It finally describes objects covered with this coating.
摘要翻译：本发明涉及在微米和纳米尺寸范围内制造具有受控结构的多孔涂层的方法。具体地但非排他性地，本发明涉及一种制造具有各向异性孔径分布的涂层的方法以及使用这种涂层获得的涂层。它特别描述了使用喷墨方法以受控方式沉积这种涂层。它还涉及在微米和纳米尺寸范围内具有受控结构的多孔涂层。该涂层具有10纳米和10毫米之间的厚度，并且其孔隙率以孔径分布是各向异性的方式产生。它最终描述了这种涂层覆盖的物体。

104. 发明公开

EP2026853A2 ANISOTROPIC NANOPOROUS COATINGS FOR MEDICAL IMPLANTS 有权
标题翻译：各向异性纳米的多孔涂层医用植入物
公开(公告)号：EP2026853A2
公开(公告)日：2009-02-25
申请号：EP07845258.8
申请日：2007-05-16
申请人： DEBIOTECH S.A.
发明人： PIVETEAU, Laurent-Dominique , HOFMANN, Heinrich , NEFTEL, Frédéric
IPC分类号： A61L27/28 , A61L27/30 , A61L27/54 , A61L31/08 , A61F2/82 , A61C8/00
CPC分类号： A61M31/002 , A61B17/68 , A61C8/0004 , A61C8/0013 , A61C8/0015 , A61C2008/0046 , A61F2/82 , A61F2240/001 , A61F2250/0068 , A61L27/28 , A61L27/56 , A61L31/08 , A61L31/146 , A61L2400/12 , Y10T428/24942 , Y10T428/249979
摘要： The present invention relates to a process for fabricating a porous coatings with controlled structure in the micro and nano-size domain. In particular, but not exclusively, it relates to a process for fabricating coatings with an anisotropic pore size distribution and to coatings obtained using such coatings. It describes in particular the use of ink-jet method to deposit in a controlled way such coatings. It also relates to porous coatings with controlled structure in the micro and nano-size domain. The coating has a thickness between 10 nanometers and 10 millimeters and its porosity is created in such a way that the pore size distribution is anisotropic. It finally describes objects covered with this coating.

105. 发明公开

EP1924301A1 REINFORCED POROUS COATING 审中-公开
标题翻译：增强多孔涂层
公开(公告)号：EP1924301A1
公开(公告)日：2008-05-28
申请号：EP06809323.6
申请日：2006-09-15
申请人： DEBIOTECH S.A. , Axis Biodental S.A.
发明人： HOFMANN, Heinrich , NEFTEL, Frédéric , PIVETEAU, Laurent-Dominique
IPC分类号： A61L27/28 , A61L31/08
CPC分类号： A61L27/28 , A61L27/54 , A61L27/56 , A61L31/08 , A61L31/146 , A61L31/16 , A61L2300/00 , Y10T428/249978
摘要： The present invention relates to a process for manufacturing a porous coating with structures in the micro or nano-size domain characterized by the following steps : - providing a support having a surface, - depositing on said surface one mono-layer of temporary particles, - depositing a coating on said temporary particles in such a way that the thickness of said coating is less than the particle diameter, - eliminating said temporary particles and thereby obtaining a porous coating, the pores of said coating corresponding to the spaces previously occupied by the temporary particles and at least a part of the pores communicating with the external environment, - applying a coating fixation step, characterized by the fact that said temporary particles are deposited on said surface in such a way that, after particle deposition, more than 50 % of the temporary particles are in contact with a maximum of two adjacent particles and otherwise are separated by an empty space. The invention also concerns a coating and an object which can be obtained with this process.

106. 发明公开

EP1924300A2 POROUS COATING LOADED WITH A LIQUID OR A SOLID SUBSTANCE 有权
标题翻译：多孔结构，液体或固体物质受压涂料
公开(公告)号：EP1924300A2
公开(公告)日：2008-05-28
申请号：EP06809320.2
申请日：2006-09-15
申请人： DEBIOTECH S.A. , Axis Biodental S.A.
发明人： HOFMANN, Heinrich , NEFTEL, Frédéric , PIVETEAU, Laurent-Dominique
IPC分类号： A61L27/28 , A61K31/08
CPC分类号： A61L27/28 , A61L27/54 , A61L27/56 , A61L31/08 , A61L31/146 , A61L31/16 , A61L2300/00 , Y10T428/249978
摘要： The present invention relates to a process for manufacturing a porous coating with structures in the micro or nano-size domain characterized by the following steps : - providing a support having a surface, - depositing on said surface one mono-layer of temporary particles, - depositing a coating on said temporary particles in such a way that the thickness of said coating is less than the particle diameter, - eliminating said temporary particles and thereby obtaining a porous coating, the pores of said coating corresponding to the spaces previously occupied by the temporary particles and at least a part of the pores communicating with the external environment, - applying a coating fixation step, characterized by the fact that it furthermore comprise a filling step where said pores are at least partially filled with a liquid or solid substance. The invention also concerns a coating and an object which can be obtained with this process.

107. 发明公开

EP1825144A2 PERISTALTIC PUMP 有权
标题翻译：软管泵
公开(公告)号：EP1825144A2
公开(公告)日：2007-08-29
申请号：EP05794814.3
申请日：2005-10-20
申请人： DEBIOTECH S.A.
发明人： JUNOD, Florent , NEFTEL, Frédéric
IPC分类号： F04B43/14 , F04B43/12
CPC分类号： F04B43/14 , F04B43/1269 , F04B2205/01 , F04B2205/05
摘要： Peristaltic pump comprising - a pump body (3) with a face containing at least a first groove (4) covered by a flexible membrane (2) fixed to said pump body (3), in such a way as to form a fluid tight channel, said membrane (2) furthermore comprising a sealing ridge (19) which is in permanent contact against said groove (4) so as to obtain a resting fluid tight sealing segment in the channel, - a movable pressure element (7) adapted to temporarily press a portion of the membrane (2) above said groove (4) and form a moving sealing segment in the channel, - driving means (8) adapted to move said movable pressure element (7) along said groove, said driving means (8) furthermore being adapted to move said movable pressure element (7) exclusively along a plane which is parallel to said pump body face, said sealing ridge (19) and/or said groove (4) being adapted to let said movable pressure element (7) in said parallel plane when moving over said sealing ridge (19), characterized by the fact that the movable pressure element (7) is rotatably fixed to an axis (9) forming part of said driving means (8), said axis (9) being parallel to the membrane (2).

108. 发明授权

EP1066068B1 DISPOSITIF DE DIALYSE PERITONEALE 有权
公开(公告)号：EP1066068B1
公开(公告)日：2006-07-12
申请号：EP99910578.6
申请日：1999-04-01
申请人： DEBIOTECH S.A.
发明人： NEFTEL, Frédéric
IPC分类号： A61M1/28
CPC分类号： A61M1/28 , A61M1/1662 , A61M1/281 , A61M1/282
摘要： The invention concerns the treatment of kidney failure and more precisely a device for peritoneal dialysis. Said device is adapted to operate in TPD (Tidal Peritoneal Dialysis) mode, characterised in that it is provided with a system for varying the dialysate exchange parameters in course of time. Said system is designed so as to vary the duration between two dialysate fraction exchange cycles.
摘要翻译：本发明涉及治疗肾衰竭，更准确地说是腹膜透析的装置。所述装置适于以TPD（潮气腹膜透析）模式操作，其特征在于，它提供有随时间改变透析液交换参数的系统。所述系统被设计为改变两个透析液级分交换循环之间的持续时间。

109. 发明公开

EP1648537A1 A SYSTEM FOR PERFORMING FLUID ADMINISTRATION 失效
标题翻译： SYSTEM FOR输液的腹膜实施情况
公开(公告)号：EP1648537A1
公开(公告)日：2006-04-26
申请号：EP04738121.5
申请日：2004-08-02
申请人： DEBIOTECH S.A.
发明人： NEFTEL, Frédéric , JUNOD, Florent; c/o DEBIOTECH SA , VECTEN, Didier; c/o DEBIOTECH SA
IPC分类号： A61M1/28 , F04B43/12
CPC分类号： A61M1/28 , A61M5/44 , A61M2205/128 , F04B43/1253
摘要： The invention concerns a system and a method of use of said system for performing fluid administration on a patient, the system comprising : a liquid pump (1), a liquid distribution system (2) connected to said pump (1) in such a way that liquid can flow from the liquid distribution system (2) to the pump (1) and vice versa, liquid supply means (3) for supplying liquid to a patient (4) via said liquid distribution system (2) and said pump (1), a patient conduit (5) adapted for connecting said liquid distribution system (2) to a patient (4), the system being characterized by the fact that said liquid pump (1) is unidirectional and that said liquid distribution system (2) comprises switching means designed to alternatively connect the pump enter line (56) with the supply means (3) or with the patient conduit (5).

110. 发明授权

EP0846008B1 DISPOSITIF D'INJECTION POUVANT FONCTIONNER EN CONTINU 失效
标题翻译： DEVICE FOR连续注射
公开(公告)号：EP0846008B1
公开(公告)日：2002-04-24
申请号：EP96929349.7
申请日：1996-08-20
申请人： DEBIOTECH S.A.
发明人： NEFTEL, Frédéric , BOUVIER, Bernard
IPC分类号： A61M5/168
CPC分类号： A61M5/16827 , A61M5/007
摘要： A continuously operating infusion device has two discrete infusion bottles (12) for at least one fluid to be injected to a patient by means of a tubing, each bottle having means (51) for detecting that the infusion of the fluid contained therein is completed and for controlling fluid flow interruption means (53). The device has an upstream infusion device (10) with two feed tubes (50) connected to a bottle (12) and a downstream infusion device (70) with fluid pumping means (72, 84) connected to the patient by a downstream tube (78) as well as to connector means (54). The device is useful for conducting infusions prior to an imaging procedure by X-ray or NMR scanner.

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