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101. 发明申请

WO2009012099A2 BORON-ENHANCED SHAPE MEMORY ENDOPROSTHESES 审中-公开
标题翻译： BORON增强形状记忆内吞
公开(公告)号：WO2009012099A2
公开(公告)日：2009-01-22
申请号：PCT/US2008/069536
申请日：2008-07-09
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan , O'BRIEN, Barry
发明人： WEBER, Jan , O'BRIEN, Barry
IPC分类号： A61L27/04 , A61L27/30 , A61L27/50
CPC分类号： A61L31/022 , A61L31/084 , A61L31/088 , A61L31/128 , A61L31/14 , A61L2400/16
摘要： An endoprosthesis comprises a member capable of supporting a body passageway. The member has a surface region overlying a bulk region, and comprises a shape memory alloy and boron. The concentration of boron in the surface region is greater than the concentration of boron in the bulk region.
摘要翻译：内假体包括能够支撑身体通道的构件。该构件具有覆盖体区域的表面区域，并且包括形状记忆合金和硼。表面区域中硼的浓度大于体积区域中的硼浓度。

102. 发明申请

WO2008156666A2 HARDENED POLYMERIC LUMEN SURFACES 审中-公开
标题翻译：硬化聚合物表面
公开(公告)号：WO2008156666A2
公开(公告)日：2008-12-24
申请号：PCT/US2008/007396
申请日：2008-06-13
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan
发明人： WEBER, Jan
IPC分类号： A61M25/00
CPC分类号： A61M25/0045 , A61L29/04 , A61L29/14 , A61L2400/18 , A61M25/0009 , A61M25/0023 , A61M25/0054 , A61M2025/0062
摘要： Apparatuses, systems, and methods for surface modification of catheters. The surface modification can be localized to a lumen surface of the catheter. The surface modification to the lumen surface extends radially into the catheter body a predetermined distance to provide a hardened zone having a hardness that is greater than a hardness of an exterior surface of the catheter body.
摘要翻译：导管表面改性的装置，系统和方法。表面改性可以定位于导管的内腔表面。对内腔表面的表面改性径向延伸到导管主体预定距离以提供具有大于导管主体外表面的硬度的硬度的硬化区域。

103. 发明申请

WO2008057991A2 ION BOMBARDMENT OF MEDICAL DEVICES 审中-公开
标题翻译：医疗器械的离子轰击
公开(公告)号：WO2008057991A2
公开(公告)日：2008-05-15
申请号：PCT/US2007/083432
申请日：2007-11-02
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan , SCHEVCHENKO, Natalia
发明人： WEBER, Jan , SCHEVCHENKO, Natalia
IPC分类号： A61F2/90 , A61F2/86
CPC分类号： A61F2/86 , A61C8/0012 , A61C8/0018 , A61C8/0039 , A61C2008/0046 , A61F2/91 , A61F2/915 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2210/0076 , A61F2250/0024 , A61F2250/0068
摘要： A medical device can include a metal member including a porous first portion with pores extending from a surface of the metal member into the first portion and non-porous second portion. The first portion can have a porosity that varies with distance from the surface of the metal member.
摘要翻译：医疗装置可以包括金属构件，该金属构件包括具有从金属构件的表面延伸到第一部分和无孔第二部分中的孔的多孔第一部分。第一部分可以具有随着距离金属构件表面的距离而变化的孔隙率。

104. 发明申请

WO2008051680A2 MEDICAL DEVICE HYDROGEN SURFACE TREATMENT BY ELECTROCHEMICAL REDUCTION 审中-公开
标题翻译：医疗器械氢表面处理电化学减少
公开(公告)号：WO2008051680A2
公开(公告)日：2008-05-02
申请号：PCT/US2007/079841
申请日：2007-09-28
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ATANASOSKA, Liliana , WEBER, Jan , WARNER, Robert W.
发明人： ATANASOSKA, Liliana , WEBER, Jan , WARNER, Robert W.
IPC分类号： C25D11/00
CPC分类号： C25D11/00 , A61L31/022 , A61L31/148 , A61L31/16 , A61L2400/18 , C25D9/12
摘要： Medical devices, such as endoprostheses, and methods of making the devices are described. In some implementations, a stent has a surface region of magnesium with a protective surface layer of magnesium hydride obtained by hydrogen surface modification through an H-EIR process, offering enhanced corrosion resistance.
摘要翻译：描述医疗装置，例如内用假体，以及制造装置的方法。在一些实施方案中，支架具有通过H-EIR工艺通过氢表面改性获得的具有氢化镁保护表面层的镁的表面区域，提供增强的耐腐蚀性。

105. 发明申请

WO2008034030A2 MAGNETIZED BIOERODIBLE ENDOPROSTHESIS 审中-公开
标题翻译：磁化生物学内吞
公开(公告)号：WO2008034030A2
公开(公告)日：2008-03-20
申请号：PCT/US2007/078449
申请日：2007-09-14
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan , ATANASOSKA, Liliana
发明人： WEBER, Jan , ATANASOSKA, Liliana
IPC分类号： A61L31/02 , A61L31/08 , A61L31/10 , A61L31/14 , A61L31/16
CPC分类号： A61L31/148 , A61L31/022 , A61L31/088 , A61L31/10 , A61L31/16 , A61L2300/416
摘要： Endoprostheses (e.g., stents) having a magnetized portion and a bioerodible portion are disclosed.
摘要翻译：公开了具有磁化部分和生物侵蚀部分的内假体（例如，支架）。

106. 发明申请

WO2008017028A3 ENDOPROSTHESIS WITH THREE-DIMENSIONAL DISINTEGRATION CONTROL 审中-公开
公开(公告)号：WO2008017028A3
公开(公告)日：2008-02-07
申请号：PCT/US2007/075072
申请日：2007-08-02
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan , ATANASOSKA, Liliana
发明人： WEBER, Jan , ATANASOSKA, Liliana
IPC分类号： C23C4/12 , A61L27/00 , A61F2/06 , B22F7/00 , C23C8/24 , C23C30/00
摘要： The present invention comprises a medical device (10) having a support structure (4) made from alternating layers.

107. 发明申请

WO2007121323A2 ENDOPROSTHESIS HAVING A FIBER MESHWORK DISPOSED THEREON 审中-公开
标题翻译：具有纤维网状结构的内窥镜
公开(公告)号：WO2007121323A2
公开(公告)日：2007-10-25
申请号：PCT/US2007/066568
申请日：2007-04-12
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan , FENG, James, Q. , ATANASOSKA, Liliana
发明人： WEBER, Jan , FENG, James, Q. , ATANASOSKA, Liliana
IPC分类号： A61F2/06 , A61L31/14 , A61F2/00
CPC分类号： A61F2/07 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2250/003 , A61L31/10 , A61L31/148
摘要： The present invention comprises a medical device having an underlying structure on which is disposed a fiber meshwork composed of one or more fibers of substantially uniform diameter. The fiber meshwork may optionally have a multi-layer structure disposed upon it. Either or both of the fiber meshwork or the multi-layer structure may have one or more therapeutic agents absorbed within it. The fiber meshwork is permeable to body fluids and thereby permits body fluids to contact the underlying structure to facilitate its controlled disintegration. The fiber meshwork degrades more slowly than the underlying structure thereby permitting release of the therapeutic agent over a timescale longer than that of the lifetime of the underlying structure, while also ensuring that the support function of the underlying structure is not abrogated by the disintegration of the underlying structure.
摘要翻译：本发明包括具有下面结构的医疗装置，其上设置有由一个或多个基本均匀直径的纤维组成的纤维网。纤维网可以可选地具有设置在其上的多层结构。纤维网或多层结构中的任一种或两者可以具有吸收在其中的一种或多种治疗剂。纤维网可以渗透体液，从而允许体液接触下面的结构以促进其受控的分解。纤维网织物比下面的结构降解得更慢，从而允许治疗剂在比基础结构的寿命更长的时间尺度上释放，同时还确保底层结构的支撑功能不被废除底层结构。

108. 发明申请

WO2007061792A2 BIFURCATION STENT DELIVERY SYSTEM 审中-公开
标题翻译：分叉式输送系统
公开(公告)号：WO2007061792A2
公开(公告)日：2007-05-31
申请号：PCT/US2006/044571
申请日：2006-11-17
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan , JAGGER, Karl, A. , EIDENSCHINK, Tracee
发明人： WEBER, Jan , JAGGER, Karl, A. , EIDENSCHINK, Tracee
IPC分类号： A61F2/84
CPC分类号： A61F2/954 , A61F2/856 , A61F2/958 , A61F2002/065
摘要： A catheter assembly includes a catheter, a balloon, a plurality of guidewire housings, and a stent. The stent is disposed about the balloon. At least a portion of each of the guidewire housings is positioned between the stent and the balloon.
摘要翻译：导管组件包括导管，球囊，多个导丝壳体和支架。支架围绕气球设置。每个导丝壳体的至少一部分位于支架和气囊之间。

109. 发明申请

WO2007015790A2 RESONATOR FOR MEDICAL DEVICE 审中-公开
标题翻译：医疗器械共振器
公开(公告)号：WO2007015790A2
公开(公告)日：2007-02-08
申请号：PCT/US2006/027598
申请日：2006-07-14
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan
发明人： WEBER, Jan
IPC分类号： A61F2/86 , G01R33/28 , A61B5/055
CPC分类号： A61F2/86 , A61B5/055 , A61F2230/0091 , A61F2250/0001 , A61F2250/0045 , G01R33/286
摘要： A resonator device including an induction coil, a conductive member positioned adjacent the induction coil, and a dielectric layer between at least a portion of the induction coil and the conductive member to form a capacitor structure. In one embodiment, the conductive member can be a stent. In an alterative embodiment, the conductive member can be a conductive film. In an additional embodiment, the dielectric layer can have a dielectric constant that changes in a predetermined fashion between at least a portion of the induction coil and the conductive member to allow for a uniform current distribution in the resonator device. The dielectric layer can also include a flexible elongate body.
摘要翻译：一种谐振器装置，包括感应线圈，与感应线圈相邻的导电部件，以及在感应线圈的至少一部分与导电部件之间形成电容器结构的电介质层。在一个实施例中，导电构件可以是支架。在替代实施例中，导电构件可以是导电膜。在另外的实施例中，电介质层可以具有在感应线圈的至少一部分和导电构件之间以预定方式改变的介电常数，以允许谐振器装置中的均匀电流分布。电介质层还可以包括柔性细长体。

110. 发明申请

WO2006026187A2 STENTS WITH DRUG ELUTING COATINGS 审中-公开
标题翻译：带药液涂层的手套
公开(公告)号：WO2006026187A2
公开(公告)日：2006-03-09
申请号：PCT/US2005/029529
申请日：2005-08-18
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan
发明人： WEBER, Jan
IPC分类号： A61L31/02 , A61L31/10 , A61L31/16
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/416 , A61L2300/624
摘要： The present invention relates generally to medical devices, preferably a stent, having a drug eluting surface coated or covered with a coating of particles comprising at least an outer layer, an inner layer, and a core comprising a therapeutic agent. Specifically, the invention relates to medical devices having a hydrophilic coating comprising particles with a hydrophilic outer layer, a hydrophobic inner layer, and a core comprising a hydrophobic therapeutic agent, as well as medical devices having a hydrophobic coating comprising particles with a hydrophobic outer layer, a hydrophilic inner layer, and a core comprising a hydrophilic therapeutic agent. The coating, outer layer, and inner layer are preferably biodegradable and capable of providing sustained release of the therapeutic agent over a time period. The invention also relates to methods of making and methods of using the coated or covered medical device.
摘要翻译：本发明一般涉及医疗装置，优选支架，其具有用包含至少外层，内层和包含治疗剂的芯的颗粒涂层涂覆或覆盖的药物洗脱表面。具体地，本发明涉及具有亲水性涂层的医疗装置，其包括具有亲水外层的颗粒，疏水性内层和包含疏水性治疗剂的芯，以及具有疏水性涂层的医疗装置，所述疏水涂层包含具有疏水性外层的颗粒，亲水性内层和包含亲水性治疗剂的核心。涂层，外层和内层优选是可生物降解的并且能够在一段时间内提供治疗剂的持续释放。本发明还涉及制造方法和使用涂覆或覆盖的医疗装置的方法。

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