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91. 发明专利

JPS63151847A ULTRASONIC DETECTOR FOR LIQUID CHROMATOGRAPH 失效
公开(公告)号：JPS63151847A
公开(公告)日：1988-06-24
申请号：JP29870086
申请日：1986-12-17
申请人： SHOWA DENKO KK , FUJI INDUSTRIES CO LTD
发明人： NAKAMURA SHIGERU , YAMADA TSUYOSHI , MATSUZAKI TAKESHI , SUZUKI HIDEYUKI
IPC分类号： G01N30/62 , G01N29/00 , G01N29/024 , G01N29/22 , G01N30/76
摘要： PURPOSE:To enable detection of trace components even at a high pressure and a high flow rate, by transmitting an ultrasonic wave to an eluate from a column of a liquid chromatograph to receive the reflected wave from the liquid. CONSTITUTION:A sample is injected into an eluate and flows into a column of a liquid chromatograph to separate desired components with the column, the eluate from which is fed to an inflow port 11 of an ultrasonic detector 16 and reaches an ultrasonic detector section 13. Ultrasonic pulse is transmitted to the eluate from an ultrasonic detector 14 to be reflected with a reflection wall 15 as opposed thereto and the reflected wave thereof is received again with the ultrasonic detector 14. The reception pulse thereof is converted into an output signal with a converter to obtain a chromatogram. Thus, the eluate flows between the ultrasonic detector and the reflection wall facing each other thereby enabling highly accurate detection of trace components depending on a difference in the propagation rate of the eluate.

92. 发明专利

JPS6110772B2 JPS6110772B2 - 失效
公开(公告)号：JPS6110772B2
公开(公告)日：1986-03-31
申请号：JP18843380
申请日：1980-12-26
申请人： Shimadzu Corp
发明人： OOKUBO KUNIHIKO
IPC分类号： G01N21/00 , G01N21/17 , G01N21/27 , G01N29/00 , G01N30/76
CPC分类号： G01N21/1702
摘要： PURPOSE:To add a material discriminating function to a detector of a chromatograph, by securing such constitution in which a pressure-sensitive element is provided to a sample cell to detect the periodical pressure change of a material contained in the sample cell which is caused by the intermittent light. CONSTITUTION:The light given from a light source L are made intermittent by a shutter S and made incident to a flow cell C through a filter F which absorbs the absorbed spectrum beam of a carrier fluid of a liquid chromatograph passes through the cell C. Then the periodical pressure change of the carrier fluid is detected by a microphone M. Thus a chromatograph is detected. The beams passed through the cell C are condensed on a slit XS through a condenser lens XL and then made incident to a convex diffraction grating G to be dispersed. Thus a spectrum image is formed on a solid-state image pickup element P. When the peak of the output is detected for the microphone M, the output of the element P is read to obtain the information on the sample component that produced the peak output.

93. 发明专利

JPS57108739A PHOTO-ACOUSTIC ANALYZER 失效
公开(公告)号：JPS57108739A
公开(公告)日：1982-07-06
申请号：JP18843380
申请日：1980-12-26
申请人： SHIMADZU CORP
发明人： OOKUBO KUNIHIKO
IPC分类号： G01N21/00 , G01N21/17 , G01N21/27 , G01N29/00 , G01N30/76
摘要： PURPOSE:To add a material discriminating function to a detector of a chromatograph, by securing such constitution in which a pressure-sensitive element is provided to a sample cell to detect the periodical pressure change of a material contained in the sample cell which is caused by the intermittent light. CONSTITUTION:The light given from a light source L are made intermittent by a shutter S and made incident to a flow cell C through a filter F which absorbs the absorbed spectrum beam of a carrier fluid of a liquid chromatograph passes through the cell C. Then the periodical pressure change of the carrier fluid is detected by a microphone M. Thus a chromatograph is detected. The beams passed through the cell C are condensed on a slit XS through a condenser lens XL and then made incident to a convex diffraction grating G to be dispersed. Thus a spectrum image is formed on a solid-state image pickup element P. When the peak of the output is detected for the microphone M, the output of the element P is read to obtain the information on the sample component that produced the peak output.

94. 发明专利

JPS5459188A INFRARED SPECTROPHOTOMETER APPARATUS OF GAS CHROMATOGRAPHY 失效
公开(公告)号：JPS5459188A
公开(公告)日：1979-05-12
申请号：JP12630877
申请日：1977-10-19
申请人： NIPPON ELECTRIC CO
发明人： WASHIO KUNIHIKO
IPC分类号： G01N21/00 , G01N21/17 , G01N29/00 , G01N30/76
摘要： PURPOSE:To make possible the spectral measurement of high sensitivity even if the separated component gas is of low concentration by radiating wavelength variable laser to the specimen introduced into an opto-acoustic cell. CONSTITUTION:The effluent components from a gas chromatograph 1 are captured in a trap 5 via valve 3 and channel changeover valve 4. Next, the valve 3 is changed over to a carrier gas generator 2 and the carrier gas is introduced into the trap 5 which has been elevated of temperature, whereby the captured components are introduced into an opto-acoustic cell 7. Next, when the component gas having been introduced into the cell 7 absorbes modulated laser light by the chopper 11 from a wavelength variable laser 10, the absorption energy becomes heat, causing the sound pressure of the cell 7 to change. This change in the sound pressure is detected with a microphone 12, and is amplified with a lock-im amplifier 13, the output whereof is then divided by the output of a laser power meter 14 in a ratio meter 16, thus the concentration of the component may be detected as a function of wavelengths in a recorder 18 with high sensitivity.

95. 发明申请

WO2023089114A1 DETEKTIONSEINRICHTUNG FÜR DIE GASCHROMATOGRAPHIE 审中-公开
公开(公告)号：WO2023089114A1
公开(公告)日：2023-05-25
申请号：PCT/EP2022/082442
申请日：2022-11-18
申请人： FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E. V.
发明人： GRAUNKE, Thorsten , TSCHEKALINSKIJ, Wladimir , HETTENKOFER, Sebastian , JUNGER, Stephan , GARBAS, Jens-Uwe , RYBALKO, Ruslan
IPC分类号： G01N30/76 , G01N30/74 , G01N30/60
摘要： Die vorliegende Erfindung betrifft eine Detektionseinrichtung für Chromatographie, insbesondere für die Gaschromatographie. Sie weist wenigstens eine breitbandige Strahlungsquelle (1), eine Messkammer (2) mit einem Einlass für ein zu untersuchendes Medium (6), in die die Strahlung (7) der Strahlungsquelle (1) eingekoppelt wird, eine chromatographische Trenneinrichtung (5) vor dem Einlass in die Messkammer (2) und ein oder mehrere Detektoren (3) auf, durch die ein Resultat einer Wechselwirkung der in die Messkammer (2) eingekoppelten Strahlung (7) mit einem in die Messkammer (2) eingebrachten Medium erfassbar ist. Die Detektionseinrichtung lässt sich kostengünstig realisieren und vollständig miniaturisieren, bspw. in Form eines Substratstapels.

96. 发明申请

WO00012968A1 METHODS AND APPARATUS FOR INTERPRETING MEASURED LABORATORY DATA 审中-公开
标题翻译：用于解释测量实验室数据的方法和装置
公开(公告)号：WO00012968A1
公开(公告)日：2000-03-09
申请号：PCT/US1999/020125
申请日：1999-09-01
IPC分类号： A61B5/00 , B41M3/02 , G01D1/18 , G01N30/76 , G06F19/00 , G06Q50/22
CPC分类号： G06Q50/22 , G06F19/00 , G16H50/20 , Y10S128/92
摘要： Systems, methods, and computer program products for determining relative normalcy and abnormalcy of a plurality of test results are provided. Test results are transformed into respective unitized values and then graphically displayed with a unitized reference range. An analytical variation of each of the respective unitized values may be determined and displayed.
摘要翻译：提供了用于确定多个测试结果的相对正常和异常的系统，方法和计算机程序产品。测试结果被转换成相应的单位化值，然后以单位参考范围图形显示。可以确定并显示各个单位化值中的每一个的分析变化。

97. 发明授权

US11474085B2 Expanded bed affinity selection 有权
公开(公告)号：US11474085B2
公开(公告)日：2022-10-18
申请号：US15963809
申请日：2018-04-26
申请人： FloDesign Sonics, Inc.
发明人： Bart Lipkens , Rui Tostoes , Kedar C. Chitale , Benjamin Ross-Johnsrud , Walter M. Presz, Jr. , Jack Saloio
IPC分类号： G01N30/76 , G01N30/46 , G01N30/72 , G01N33/543 , B01D15/38 , B01D15/18 , C07K1/22 , G01N30/02 , C12M1/42 , C12N13/00
摘要： Separation of materials is achieved using affinity binding and acoustophoretic techniques. A column provided with a fluid mixture of materials for separation and support structures may be used with acoustic waves to block flow of the support structures. The support structures can have an affinity for one or more materials in the fluid mixture. By blocking flow of the support structures, materials bound or adhered to the support structure are also blocked.

98. 发明授权

US11085905B2 Techniques for monitoring chromatographic fluid flows 有权
公开(公告)号：US11085905B2
公开(公告)日：2021-08-10
申请号：US16439484
申请日：2019-06-12
申请人： WATERS TECHNOLOGIES CORPORATION
发明人： Abhijit Tarafder , Jonathan Belanger , Moon Chul Jung , Wade P. Leveille
IPC分类号： G01N30/76 , G01N9/32 , G08B3/10 , G08B5/36 , G08B21/18 , G01N30/02
摘要： Various embodiments are generally directed to techniques for monitoring chromatographic fluid flows, such as the flow to and/or from one or more reservoirs used in chromatographic operations, for instance. In many embodiments, the chromatographic operations may include one or more of High Performance Liquid Chromatography (HPLC), Ultra Performance Liquid Chromatography (UPLC), Ultra Performance Convergence Chromatography (UPC2), and the like. Several embodiments are particularly directed to a chromatographic fluid flow device (CFFD) for monitoring a change in density of a chromatographic fluid in a tube, such as by detecting the presence or absence of gas in the tube with an ultrasonic bubble detector. In various embodiments, the chromatographic fluid may include a solvent, a sample, or waste associated with a chromatographic operation.

99. 发明申请

US20190271671A1 USE OF AN ACOUSTIC WAVE IN A CHROMATOGRAPHY SYSTEM 审中-公开
公开(公告)号：US20190271671A1
公开(公告)日：2019-09-05
申请号：US16284942
申请日：2019-02-25
申请人： DIONEX SOFTRON GMBH
发明人： Erik BAIGAR , Christoph STROBL
IPC分类号： G01N30/76 , H01L41/053 , H01L41/09 , B01D15/10 , G01N30/38
摘要： The present invention relates to a method comprising using an acoustic wave in a chromatography system. The present invention also relates to a corresponding system and a corresponding use. The system may comprise a surface acoustic wave assembly, wherein the surface acoustic wave assembly comprises a sender unit comprising a sender transducer for sending an acoustic wave and a detection unit for detecting the acoustic wave, a substrate configured for propagation of the acoustic wave, wherein the sender transducer is connected to the substrate, wherein the substrate comprises a substrate section for propagation of the wave from the sender transducer, wherein this substrate section comprises a substrate surface, wherein the surface acoustic wave assembly further comprises at least one channel for conducting fluid, wherein this channel is partly defined by the substrate surface.

100. 发明授权

US09766215B2 Analytical system and method for detecting volatile organic compounds in water 有权
公开(公告)号：US09766215B2
公开(公告)日：2017-09-19
申请号：US14343138
申请日：2012-09-07
申请人： Kazi Z. A. Hassan , William M. Cost , John Arthur Morse , Michael L. Doutt , Glenn Stacey Geis
发明人： Kazi Z. A. Hassan , William M. Cost , John Arthur Morse , Michael L. Doutt , Glenn Stacey Geis
IPC分类号： G01N30/76 , G01N29/02 , G01N1/10 , G01N1/40 , G01N30/02
CPC分类号： G01N30/76 , G01N1/10 , G01N1/4055 , G01N29/022 , G01N2001/4066 , G01N2030/025 , G01N2291/021
摘要： An analytical system and method for detecting volatile organic chemicals in water including a coated SAW detector that provides for improved reduction of moisture at the coating of the SAW detector. A stabilized SAW sensitivity and long lasting calibration is achieved. The analytical system further includes an improved sample vessel and sparger that allow for easy grab sample analysis, while also providing efficient purging of the volatile organic compounds from the water sample. In addition, an improved preconcentrator provides a stabilized sorbent bed.

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