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91. 发明申请

WO1996037151A1 LOW PROFILE HOLDER FOR HEART VALVE PROSTHESIS 审中-公开
标题翻译：用于心脏瓣膜的低剖面保持架
公开(公告)号：WO1996037151A1
公开(公告)日：1996-11-28
申请号：PCT/US1996007394
申请日：1996-05-24
申请人： ST. JUDE MEDICAL, INC.
发明人： ST. JUDE MEDICAL, INC. , KRUEGER, Kurt, D. , VANNEY, Guy
IPC分类号： A61B17/00
CPC分类号： A61F2/2427 , Y10S623/90
摘要： A device for engaging a heart valve prosthesis (18) during implantation includes a handle (91) and a low profile holder (14). The handle (91) has a proximal end (92) and a distal end (94). The distal end (94) is attached to the low profile holder (14) which engages the heart valve prosthesis (18). The low profile holder (14) maintains an occluder (24, 26) of the heart valve (12) in a closed position during implantation. This provides a low profile to the heart valve (12) and holder (14) which facilitates insertion through a trocar in a patient.
摘要翻译：用于在植入期间接合心脏瓣膜假体（18）的装置包括手柄（91）和低轮廓保持器（14）。手柄（91）具有近端（92）和远端（94）。远端（94）附接到接合心脏瓣膜假体（18）的低轮廓保持器（14）。在植入期间，薄型保持器（14）将心脏瓣膜（12）的封堵器（24,26）保持在关闭位置。这提供了心脏瓣膜（12）和保持器（14）的低轮廓，其有利于穿过病人的套管针插入。

92. 发明申请

WO1995025466A1 PACKAGING SHEATHS FOR INTRA-AORTIC BALLOON CATHETERS 审中-公开
标题翻译：包装用于内部气泡导管
公开(公告)号：WO1995025466A1
公开(公告)日：1995-09-28
申请号：PCT/US1995003465
申请日：1995-03-20
申请人： ST. JUDE MEDICAL, INC.
发明人： ST. JUDE MEDICAL, INC. , ANDREWS, Robert, R. , EDELMAN, William , HUNT, Ilyssa, A.
IPC分类号： A61B17/00
CPC分类号： A61M25/002
摘要： An intra-aortic balloon packaging sheath (10) is provided which includes a long slim extruded plastic tube (12) for storing a furled thin-walled intra-aortic balloon. An entry section (14) of the same plastic is injection molded onto one end (26) of the tube, with the entry section (14) including an outwardly flared entry port surface (22) which is spaced from one end (26) of the tube, and an internal passageway (38) which is co-linear and congruent with the end of the tube (26) through the intersection of the second internal passageway (32) with the outwardly flared passageway (22). Thereby a smooth internal surface (36) is provided through the flared passageway (22) into the internal passageway (38) and through the latter into the tube (12). The exit end (16) is reformed by being inverted outwardly and back.
摘要翻译：提供了一种主动脉内气囊包装护套（10），其包括用于储存卷曲的薄壁主动脉内球囊的长纤维挤出塑料管（12）。相同塑料的入口部分（14）被注射模制到管的一端（26）上，入口部分（14）包括向外扩张的入口表面（22），该进口端口表面与第二端所述管和内部通道（38）通过所述第二内部通道（32）与所述向外扩张的通道（22）的相交而与所述管（26）的所述端部共线并且一致。由此，通过扩张通道（22）将平滑的内表面（36）提供到内部通道（38）中，并通过该内部通道（36）进入管道（12）。出口端（16）通过向外和向后反转而重新形成。

93. 发明申请

WO1993020747A1 ELECTROSURGICAL APPARATUS AND METHOD 审中-公开
标题翻译：静电设备和方法
公开(公告)号：WO1993020747A1
公开(公告)日：1993-10-28
申请号：PCT/US1993003759
申请日：1993-04-21
申请人： ST. JUDE MEDICAL, INC. , ROSAR, George, C. , BACHOFER, Ken, W. , POKORNEY, James, L. , GRAF, James, E.
发明人： ST. JUDE MEDICAL, INC.
IPC分类号： A61B05/00
CPC分类号： A61B18/1492 , A61B18/1206 , A61B18/1233 , A61B90/39 , A61B2017/00292 , A61B2018/00083 , A61B2018/00107 , A61B2018/00642 , A61B2018/00755 , A61B2018/00761 , A61B2018/00875 , A61B2018/1213 , A61B2018/124 , A61B2018/1286 , A61B2018/144
摘要： A guide wire (15) for supporting monopolar arcing for cutting tissue and for ablating occlusions includes a flexible metal wire (302) including a distal end, an electrically insulating coating (306) extending along the wire, and an electrically and thermally insulating tip (310) having a distal end and attached to the wire, the wire extending through the electrically and thermally insulating tip and forming an electrode (312) at the distal ends of the wire and the tip. An electrosurgical apparatus for cutting tissue and for ablating occlusions includes a pulse generator (5, 6) having a variable output impedance for selectively generating a train of pulses of electrical energy for application to a guide wire (15) having an attached electrode. The pulse generator senses the load impedance and adjusts the output impedance to match the load impedance. The generator measures the relative electrical energy produced by an arc in response to a pulse, compares the relative electrical energy to a predetermined value to determine an energy difference, and adjusts the energy of a subsequent pulse to reduce the energy difference toward zero.
摘要翻译：用于支撑用于切割组织并用于消融闭塞的单极电弧的导丝（15）包括柔性金属线（302），其包括远端，沿着线延伸的电绝缘涂层（306）和电绝热尖端 310），其具有远端并且附接到所述线，所述线延伸穿过所述电绝热顶端并在所述线的末端和所述尖端处形成电极（312）。用于切割组织和用于消融闭塞的电外科设备包括具有可变输出阻抗的脉冲发生器（5,6），用于选择性地产生用于施加到具有附接电极的导线（15）的电能脉冲串。脉冲发生器检测负载阻抗，并调整输出阻抗以匹配负载阻抗。发电机响应于脉冲测量由电弧产生的相对电能，将相对电能与预定值进行比较以确定能量差，并且调整后续脉冲的能量以将能量差向零减小。

94. 发明申请

WO1987006702A1 ELECTROCHEMICAL CONCENTRATION DETECTOR DEVICE 审中-公开
标题翻译：电化学浓度检测装置
公开(公告)号：WO1987006702A1
公开(公告)日：1987-11-05
申请号：PCT/US1987000848
申请日：1987-04-14
申请人： ST. JUDE MEDICAL, INC.
发明人： ST. JUDE MEDICAL, INC. , ROSS, Pepi , MADOU, Marc, J. , REYES, Zoila , JENSON, Joel, F. , WING, Sharon, W. , RIMER, Virginia, G.
IPC分类号： G01N27/46
CPC分类号： G01N27/3271 , Y10S435/817
摘要： An electrochemical method and apparatus for measuring a substrate as a function of electrochemical response to hydrogen peroxide concentration using immobilized enzyme electrode means, which comprises a set of planar electrodes (13, 14, 15) affixed to a base surface (11), an inner membrane (32) of a polymeric material having an enzyme bonded thereto overlying said electrodes, an outer membrane (33) adapted to restrict the passage of electrochemically interfering substances overlying the inner membrane and a housing (30) affixed to said base surface for containing said membranes, said electrodes and an aqueous sample of the substrate to be measured. A method of forming a Ag/AgCl reference electrode by electrolysis is also disclosed.
摘要翻译：一种用于使用固定化酶电极装置测量作为对过氧化氢浓度的电化学响应的函数的衬底的电化学方法和装置，其包括固定到基底表面（11）的一组平面电极（13,14,15），内部具有粘合到其上的酶的聚合材料的膜（32）覆盖在所述电极上，外膜（33），其适于限制覆盖在内膜上的电化学干扰物质的通过;以及壳体（30），其固定到所述基底表面，膜，所述电极和待测量的基底的水性样品。还公开了通过电解形成Ag / AgCl参比电极的方法。

95. 发明申请

WO2014120510A1 DEVICE FOR HEART VALVE REPAIR 审中-公开
标题翻译：心脏瓣膜修复装置
公开(公告)号：WO2014120510A1
公开(公告)日：2014-08-07
申请号：PCT/US2014/012248
申请日：2014-01-21
申请人： ST. JUDE MEDICAL, INC.
发明人： BIELEFELD, Eric E.
IPC分类号： A61B17/04 , A61F2/24 , A61B17/29
CPC分类号： A61F2/2463 , A61B17/0401 , A61B17/0466 , A61B17/0487 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0417 , A61B2017/0427 , A61B2017/0464 , A61B2017/0472 , A61B2017/0488 , A61B2017/06052 , A61F2/2466
摘要： A repair device (10, 110) for repairing a heart valve leaflet in a patient includes a hollow body (11, 111) with a capture tool (20, 120) and a tissue puncture element (30, 130) at the distal end thereof. The capture tool may be used to capture and stabilize the heart valve leaflet tissue. The tissue puncture element may puncture the leaflet tissue and deploy at least one anchor (40, 240) having a length of suture (45, 245) attached thereto. By tensioning the suture, the leaflet tissue may become plicated. The tensioned suture may then be cinched to maintain the plication. The device ma hve insted of the tissue punctur element, an anchor housing tube (330) with a blunt tip, able t be put in apposition to the leaflet. In this case the anchor has a sharpened distal tip, to peetrae the tissue.
摘要翻译：用于修复患者心脏瓣膜小叶的修复装置（10,110）包括：具有捕获工具（20,120）的中空本体（11,111）和在其远端的组织穿刺元件（30,130）。捕获工具可用于捕获和稳定心脏瓣膜小叶组织。组织穿刺元件可以刺穿小叶组织并展开至少一个具有连接到其上的缝合线长度（45,245）的锚（40,240）。通过张紧缝合线，小叶组织可能会变薄。然后可以将张紧的缝合线夹紧以维持折皱。设置有组织穿刺元件的装置，具有钝头的锚固体管（330）能够与小叶相配合。在这种情况下，锚固件具有尖锐的远端，用于剥离组织。

96. 发明申请

WO2014116519A1 PROTECTING AGAINST CEREBRAL EMBOLISM 审中-公开
标题翻译：保护小脑囊肿
公开(公告)号：WO2014116519A1
公开(公告)日：2014-07-31
申请号：PCT/US2014/012070
申请日：2014-01-17
申请人： ST. JUDE MEDICAL, INC.
发明人： HACKETT, Steven S.
IPC分类号： A61B17/12 , A61F2/01 , A61B17/00 , A61B19/00
CPC分类号： A61F2/01 , A61B2017/00358 , A61B2017/00876 , A61B2017/12054 , A61B2017/12086 , A61F2002/011 , A61F2230/0076 , A61F2250/0098
摘要： A permeable plug (10) may be temporarily deployed in a patient to protect blood vessels from blockage by various debris. The plug includes a body (15) formed from a filtering material. The body is collapsible for delivery to a location in a blood vessel and expandable to a filtering configuration in which the body occupies a cross-section of the blood vessel and is held in place by its own expansive force. At least one stud (20, 25) is connected to the body for use in deployment of the plug within the blood vessel and retrieval of the plug from the blood vessel.
摘要翻译：可渗透塞子（10）可临时展开在患者体内，以保护血管免受各种碎屑的堵塞。塞子包括由过滤材料形成的主体（15）。身体可折叠以输送到血管中的位置并且可扩展成过滤构型，其中身体占据血管的横截面并通过其自身的膨胀力保持在适当的位置。至少一个螺柱（20,25）连接到主体以用于将血栓展开在血管内并从血管中取出塞子。

97. 发明申请

WO2013022585A1 APPARATUS AND METHOD FOR HEART VALVE REPAIR 审中-公开
标题翻译：用于心脏瓣膜修复的装置和方法
公开(公告)号：WO2013022585A1
公开(公告)日：2013-02-14
申请号：PCT/US2012/047296
申请日：2012-07-19
申请人： ST. JUDE MEDICAL, INC. , BIELEFELD, Eric, E.
发明人： BIELEFELD, Eric, E.
IPC分类号： A61B17/064 , A61B17/068 , A61F2/24 , A61B17/11 , A61B17/29
CPC分类号： A61F2/2487 , A61B17/068 , A61B17/10 , A61B2017/00243 , A61B2017/00349 , A61B2017/00783 , A61B2017/0649 , A61B2017/1103 , A61B2017/2932 , A61B2017/3488 , A61B2090/3925 , A61F2/2442
摘要： A device and method for repairing a mitral valve leaflet 2, 3. The device 10 includes a body 16 having an annular wall 18 and at least one aperture 22 through the annular wall 18. A deployment assembly 24 mounted on the body includes at least one grasping wire 28 arranged for sliding movement in the aperture 22. Movement of the deployment assembly 24 to a deployed position relative to the body causes a free end of the grasping wire 28 to project out from the annular wall 18 through the aperture 22, and movement of the deployment assembly to a retracted position relative to the body causes the free end of the grasping wire 28 to not project out from the annular wall 18. In the deployed position, the grasping wire 28 may grasp and gather tissue of the leaflet 2,3.
摘要翻译：用于修复二尖瓣小叶2,3的装置和方法。装置10包括具有环形壁18和通过环形壁18的至少一个孔22的主体16.安装在主体上的展开组件24包括至少一个把持线28布置成在孔22中滑动运动。展开组件24相对于主体移动到展开位置使得抓持线28的自由端通过孔22从环形壁18突出，并且运动所述展开组件相对于所述主体的缩回位置使得所述抓持线28的自由端不会从所述环形壁18伸出。在展开位置，所述抓持线28可以抓住并收集所述小叶2的组织， 3。

98. 发明申请

WO2012173995A2 MULTI-LAYER STENT 审中-公开
标题翻译：多层架构
公开(公告)号：WO2012173995A2
公开(公告)日：2012-12-20
申请号：PCT/US2012/042059
申请日：2012-06-12
申请人： ST. JUDE MEDICAL, INC. , BENSON, Thomas M. , KHOUENGBOUA, Ott , BRAIDO, Peter N.
发明人： BENSON, Thomas M. , KHOUENGBOUA, Ott , BRAIDO, Peter N.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/82 , A61F2/90 , A61F2210/0076 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/0069 , A61F2230/008 , A61F2250/0039
摘要： A collapsible prosthetic heart valve includes a stent (100, 300, 600) and a valve assembly (200, 400, 700). The stent includes an annulus section (108, 308, 608) and at least one foldable section (110, 310, 610). The stent is movable between an unfolded condition in which the foldable section is longitudinally spaced from the annulus section, and a folded condition in which the foldable section is at least partially positioned radially adjacent the annulus section. The valve assembly is positioned within the annulus section of the stent in the folded condition of the stent.
摘要翻译：可折叠假体心脏瓣膜包括支架（100,300,600）和阀组件（200,400,700）。支架包括环形部分（108,308,608）和至少一个可折叠部分（110,310,610）。支架可在可折叠部分与环形部分纵向间隔开的展开状态和折叠状态之间移动，其中折叠部分至少部分地位于环形部分的径向附近。瓣膜组件在支架的折叠状态下定位在支架的环形部分内。

99. 发明申请

WO2012142373A1 OPTICAL COHERENCE TOMOGRAPHY CATHETER FOR ELASTOGRAPHIC PROPERTY MAPPING OF LUMENS UTILIZING MICROPALPATION 审中-公开
标题翻译：用于使用微波的光学的光学性质映射的光学相干导管
公开(公告)号：WO2012142373A1
公开(公告)日：2012-10-18
申请号：PCT/US2012/033462
申请日：2012-04-13
申请人： ST. JUDE MEDICAL, INC. , SLIWA, John , LIU, Yu
发明人： SLIWA, John , LIU, Yu
IPC分类号： A61B5/00 , A61B5/02 , A61M25/00
CPC分类号： A61B5/0066 , A61B5/0053 , A61B5/02007 , A61B8/485 , A61M25/007 , A61M25/0082 , A61M29/02
摘要： An optical coherence tomography (OCT) catheter, for performing high performance elastographic deformation mapping of tissues and plaques, comprises: a catheter (20) having an elongated catheter body extending longitudinally between a proximal end and a distal end along a longitudinal axis, the catheter body including a distal portion (24) at the distal end and a catheter lumen (26); a palpator (30), disposed in the distal portion, to apply one of a directed fluid or a mechanical indenter (130) to produce a surface - applied palpation force to a target area (50) of the interior body to mechanically displace the interior body and cause elastographic deformation of the target area of one or more surface and subsurface tissues and plaques; and an OCT imaging sensor (34), disposed in the distal portion, to direct and deliver an OCT beam (60) for OCT deformation detection including elastographic deformation measurement to provide elastographic mapping of the target area.
摘要翻译：用于执行组织和斑块的高性能弹性变形测绘的光学相干断层扫描（OCT）导管包括：导管（20），其具有沿着纵向轴线在近端和远端之间纵向延伸的细长导管体，所述导管主体包括在远端的远侧部分（24）和导管内腔（26）; 设置在所述远侧部分中的触发器（30），以施加有向流体或机械压头（130）中的一个以产生对所述内部主体的目标区域（50）的表面施加的触诊力，以机械地移动所述内部造成一个或多个表面和地下组织和斑块的目标区域的弹性变形; 以及设置在所述远端部分中的OCT成像传感器（34），用于引导和输送用于OCT变形检测的OCT束（60），包括弹性变形测量以提供所述目标区域的弹性图。

100. 发明申请

WO2012142227A1 SINGLE TRANSDUCER WITH ANGULAR ORIENTATION FOR LESION FEEDBACK IN ABLATION CATHETER 审中-公开
标题翻译：单向传感器，带有反射导管中的反射反馈的单向传感器
公开(公告)号：WO2012142227A1
公开(公告)日：2012-10-18
申请号：PCT/US2012/033227
申请日：2012-04-12
申请人： ST. JUDE MEDICAL, INC. , SLIWA, John , MA, Zhenyi , MORSE, Stephen
发明人： SLIWA, John , MA, Zhenyi , MORSE, Stephen
IPC分类号： A61B8/12 , A61B18/14
CPC分类号： A61B8/4483 , A61B8/085 , A61B8/12 , A61B8/445 , A61B8/5223 , A61B18/1492 , A61B2017/00106 , A61B2017/003 , A61B2018/00357 , A61B2018/00738 , A61B2018/00815 , A61B2018/00982 , A61B2090/065 , A61B2090/3966 , A61B2217/007
摘要： An ablation catheter comprises: an elongated catheter body (1b) extending along a longitudinal axis; at least one ablation element disposed in a distal portion which is adjacent the distal end of the catheter body to ablate a targeted tissue region outside the catheter body; a single pulse-echo ultrasonic transducer (1c, 1d) disposed in the distal portion and arranged to emit and receive an acoustic beam along a centroid in a beam direction, at a transducer angle (θ Xc ) of about 30-60 degrees relative to a distal direction of the longitudinal axis (Xc) at a location of intersection between the longitudinal axis and the beam direction of the centroid of the acoustic beam; and a mechanism to manipulate the distal portion in movement including rotation of at least the distal portion around the longitudinal axis. The single ultrasonic transducer emits and receives acoustic pulses to provide lesion information in the targeted tissue region being ablated.
摘要翻译：消融导管包括：沿着纵向轴线延伸的细长导管主体（1b）; 至少一个消融元件设置在远侧部分中，所述远端部分邻近所述导管主体的远端以烧蚀所述导管主体外部的目标组织区域; 一个单脉冲回波超声波换能器（1c，1d），设置在远端部分中，并且被布置成沿着波束方向沿着心形发射和接收声束，换能器角度（θXc）相对于纵向轴线（Xc）的远端方向在声束的质心的纵向轴线和梁的方向之间的交叉位置处; 以及用于操纵所述远端部分的运动的机构，包括至少所述远侧部分围绕所述纵向轴线的旋转。单个超声换能器发射和接收声脉冲以在被烧蚀的目标组织区域中提供病变信息。

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