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91. 发明授权

US10125073B2 2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol and preparation method therefor 有权
公开(公告)号：US10125073B2
公开(公告)日：2018-11-13
申请号：US15556060
申请日：2016-03-03
申请人： CHUNGBUK NATIONAL UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION
发明人： Jin Tae Hong , Hee Pom Lee , Young Wan Ham , Chun Sik Kim , Heon Sang Jung
IPC分类号： C07C43/23 , C07C41/30
摘要： Provided herein are 2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol having a novel structure capable of being used to prevent or treat all diseases associated with NF-κB, IKK and STAT3, and a method of preparing the same.

92. 发明授权

US09855365B2 Production method for biomedical and industrial material using ceramic derived from birds' beaks 有权
公开(公告)号：US09855365B2
公开(公告)日：2018-01-02
申请号：US14360169
申请日：2012-11-23
申请人： CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION , KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION , INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY
发明人： Seok Hwa Choi , Jun Sik Son , Seong Soo Kang , Chang Ho Lee
IPC分类号： A61L27/12 , C04B35/447 , C04B35/622 , A61L27/36 , C04B35/111 , C04B35/486 , C04B35/626 , C04B35/634 , C04B38/06 , C04B35/64 , A61L27/46 , A61L27/18 , C04B111/00
CPC分类号： A61L27/12 , A61L27/18 , A61L27/3608 , A61L27/46 , A61L2430/02 , C04B35/111 , C04B35/447 , C04B35/486 , C04B35/62204 , C04B35/62218 , C04B35/62231 , C04B35/62645 , C04B35/62655 , C04B35/634 , C04B35/64 , C04B38/0615 , C04B2111/00836 , C04B2235/3208 , C04B2235/3212 , C04B2235/3244 , C04B2235/36 , C04B2235/447 , C04B2235/5252 , C04B2235/5256 , C04B2235/5427 , C04B2235/5436 , C04B2235/5445 , C04B2235/5454 , C04B2235/604
摘要： The present invention relates to a method for preparing a ceramic powder from a bone of a bird's beak, a method for preparing biomedical or industrial ceramic materials by using the ceramic powder derived from a bone of a bird's beak, and a biomedical or industrial ceramic material prepared by the method thereof. The use of the present ceramic powder for manufacturing biomedical or industrial ceramic materials is safer than the use of the ceramic powder derived from allogenic bone or xenogeneic bone. In addition, the ceramic powder of the present invention can be prepared on a mass production basis. Furthermore, the ceramic material prepared using the ceramic powder of the present invention is more biocompatible than that prepared using artificially synthetic ceramic.

93. 发明申请

US20170352044A1 METHOD AND SYSTEM FOR EVALUATING RELIABILITY BASED ON ANALYSIS OF USER ACTIVITIES ON SOCIAL MEDIUM 审中-公开
公开(公告)号：US20170352044A1
公开(公告)日：2017-12-07
申请号：US15535713
申请日：2015-12-31
申请人： CHUNGBUK NATIONAL UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
发明人： Jaesoo YOO , Kyoungsoo BOK , Jongtae LIM , Jinkyung YUN
IPC分类号： G06Q30/02 , G06F17/11 , G06F17/18 , G06Q50/00
CPC分类号： G06Q30/0201 , G06F17/11 , G06F17/18 , G06Q50/01
摘要： Disclosed are a method and system for evaluating reliability on the basis of an analysis on user activities on a social medium. The method of evaluating reliability of information in a social media service includes calculating an evaluation score of information provided by an information provider on the basis of a social activity of each of a plurality of information consumers relating to the information, and calculating a reputation score of the information provider in a category of the information on the basis of the category and the evaluation score of the information.

94. 发明授权

US09741352B2 Method and apparatus for processing an audio signal 有权
公开(公告)号：US09741352B2
公开(公告)日：2017-08-22
申请号：US15089918
申请日：2016-04-04
申请人： LG Electronics Inc. , CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人： Gyuhyeok Jeong , Daehwan Kim , Ingyu Kang , Lagyoung Kim , Kibong Hong , Zhigang Piao , Insung Lee , Jongha Lim , Sanghyeon Moon , Byungsuk Lee , Hyejeong Jeon
IPC分类号： G06F17/00 , G10L19/038 , G10L19/20 , G10L19/028 , G10L19/002 , G10L19/02 , G10L19/22 , G10L21/038
CPC分类号： G10L19/038 , G10L19/002 , G10L19/0204 , G10L19/0212 , G10L19/028 , G10L19/20 , G10L19/22 , G10L21/038
摘要： The present invention relates to a method for processing an audio signal, comprising: a step of performing a frequency conversion process on an audio signal to obtain a plurality of frequency transform coefficients; a step of selecting either a general mode or a non-general mode, on the basis of a pulse ratio, for the frequency transform coefficients having a high frequency band from among the plurality of frequency transform coefficients; and a step of performing, if the non-general mode is selected, the following steps: extracting a predetermined number of pulses from the frequency transform coefficients having the high frequency band, and generating pulse information; generating an original noise signal from the frequency transform coefficients having the high frequency band, excluding the pulses; generating a reference noise signal using the frequency transform coefficient having a low frequency band from among the plurality of frequency transform coefficients; and generating noise position information and noise energy information using the original noise signal and the reference noise signal.

95. 发明授权

US09689043B2 Method for treating muscle-invasive bladder cancer, containing S100A9 and EGFR inhibitors and cisplatin as active ingredients 有权
公开(公告)号：US09689043B2
公开(公告)日：2017-06-27
申请号：US14744468
申请日：2015-06-19
申请人： CHUNGBUK NATIONAL UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION
发明人： Wun-Jae Kim , Seok-Joong Yun , Won-Tae Kim
IPC分类号： C12Q1/68 , G01N33/574 , C12N15/113 , A61K39/395
CPC分类号： C12Q1/6886 , A61K39/39533 , C12N15/113 , C12N2310/14 , C12N2320/31 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G01N33/57407 , G01N2333/4727 , G01N2333/71 , G01N2800/52
摘要： The present invention relates to a method for predicting the probability of muscle-invasive bladder cancer (MIBC) recurrence or metastasis, a method for providing information on a personalized medicine of MIBC, and a pharmaceutical composition for treating MIBC, containing S100A9 and EGFR inhibitors and cisplatin as active ingredients. According to the present invention, it is possible to accurately predict a prognosis after chemotherapy of an MIBC patient, to provide information on cisplatin sensitivity in the provision of a personalized medicine for chemotherapy of an MIBC patient, and to increase the cisplatin sensitivity of an MIBC patient by concomitantly administering S100A9 and EGFR inhibitors together with a conventional cisplatin.

96. 发明授权

US09289444B2 Composition for promoting hematogenesis containing quercetin 3-O-β-(2″-galloyl)-rhamnopyranoside as active ingredient 有权
标题翻译：用于促进含有槲皮素3-O-和bgr-（2“ - 半乳糖） - 吡喃葡萄糖苷作为活性成分的血液发生的组合物
公开(公告)号：US09289444B2
公开(公告)日：2016-03-22
申请号：US14002850
申请日：2012-01-09
申请人： Byeong Woo Ahn , Young Soo Kim , Heon Sang Jeong , Sang-Kyung Shin , Tae-Wang Kim , So-Young Youm
发明人： Byeong Woo Ahn , Young Soo Kim , Heon Sang Jeong , Sang-Kyung Shin , Tae-Wang Kim , So-Young Youm
IPC分类号： A61K31/7048
CPC分类号： A61K31/7048 , A23V2002/00 , A23V2200/306
摘要： This invention relates to a composition for promoting hematopoiesis and for treating, preventing or alleviating cytopenia or bone marrow failure comprising quercetin 3-O-β-(2″-galloyl)-rhamnopyranoside (QGR) as active ingredient. The present active compound QGR (i) increases dose dependently the mRNA expression of cytokines involved in hematopoiesis including stem cell factor, granulocyte-macrophage colony stimulating factor and erythropoietin from mouse bone marrow mononuclear cells, (ii) promotes the formation of burst forming unit-erythroid and colony forming unit-fibroblast, (iii) stimulates the generation of cells positive for TER-119, a specific marker of mouse erythroid precursors, (iv) promotes erythropoiesis, leukopoiesis, thrombopoiesis, and hemoglobin production in bone marrow failure mouse model, (v) stimulates the formation of hematopoietic stem/progenitor cells and mesenchymal stem/progenitor cells, (vi) stimulates megakaryocyte formation surrounding the blood system of damaged bone marrow, osteoid formation and bone marrow restoration through a recovery of damaged bone marrow microenvironment. The QGR of the present invention can be used for promoting hematopoiesis and treating cytopenia or bone marrow failure.
摘要翻译：本发明涉及一种用于促进造血作用并用于治疗，预防或减轻包含槲皮素3-O-和（2“ - 半酰基） - 吡喃葡萄糖苷（QGR）作为活性成分的血细胞减少或骨髓衰竭的组合物。本发明的活性化合物QGR（i）依赖性地增加参与造血细胞因子的细胞因子的mRNA表达，包括来自小鼠骨髓单核细胞的干细胞因子，粒细胞 - 巨噬细胞集落刺激因子和促红细胞生成素，（ii）促进突发形成单位 - 红细胞和集落形成单位成纤维细胞，（iii）刺激TER-119阳性的细胞的产生，TER-119是小鼠红血球前体的特异性标记，（iv）促进骨髓衰竭小鼠模型中的红细胞生成，白细胞生成，血小板生成和血红蛋白产生，（v）刺激造血干/祖细胞和间充质干细胞/祖细胞的形成，（vi）通过恢复损伤的骨髓微环境，刺激受损骨髓，骨样形成和骨髓修复周围血液系统的巨核细胞形成。本发明的QGR可用于促进造血和治疗血细胞减少或骨髓衰竭。

97. 发明申请

US20130221330A1 MULTIPLE QUANTUM DOT DEVICE AND A PRODUCTION METHOD FOR THE DEVICE 有权
标题翻译：多个量子装置和装置的生产方法
公开(公告)号：US20130221330A1
公开(公告)日：2013-08-29
申请号：US13883321
申请日：2010-11-25
申请人： Jung Bum Choi , Jong Jin Lee
发明人： Jung Bum Choi , Jong Jin Lee
IPC分类号： H01L29/66
CPC分类号： H01L29/66977 , B82Y10/00 , H01L29/66439 , H01L29/7613
摘要： The present invention relates to a multi-quantum dot device and a method of manufacturing the multi-quantum dot device. Further specifically, present invention relates to a multi-quantum dot device including a channel configured by patterning the top silicon layer of an SOI wafer to have a P-type silicon region formed by connecting a transversal region and a longitudinal region and a plurality of N-type silicon regions; gates including a plurality of tunneling barrier gates, an end of each tunneling barrier gate is positioned on the top of a transversal side of an intersection of the transversal region and the longitudinal region of the P-type silicon region to locally control a potential in the channel; a plurality of coupling gates, an end of each coupling gate is positioned on the top of a point between the intersection and another intersection adjacent to the intersection to locally control the potential in the channel; and a plurality of sensor gates, an end of each sensor gate is positioned on the top of a center of the intersection to sense a state of a quantum dot formed at the intersection; and an inversion layer gate formed on the top of the P-type silicon region to control free electron density.
摘要翻译：本发明涉及一种多量子点装置及多量子点装置的制造方法。更具体地说，本发明涉及一种多量子点器件，其包括通过对SOI晶片的顶部硅层进行构图而形成的沟道，以形成通过连接横向区域和纵向区域形成的P型硅区域和多个N 型硅区; 包括多个隧道势垒栅极的栅极，每个隧道势垒栅极的端部位于横向区域和P型硅区域的纵向区域的交叉的横向的顶部上，以局部地控制P型硅区域的电位渠道; 多个耦合栅极，每个耦合栅极的端部位于交叉点和邻接相交处的另一交叉点之间的点的顶部，以局部地控制信道中的电位; 和多个传感器门，每个传感器门的端部位于交叉点的中心的顶部，以感测形成在交叉点处的量子点的状态; 以及形成在P型硅区域的顶部上以控制自由电子密度的反型层栅极。

98. 发明申请

US20130011844A1 Novel Biomarker Indicative of Ischemic Brain Injury and Its Use 审中-公开
标题翻译：缺血性脑损伤及其用途的新型生物标志物
公开(公告)号：US20130011844A1
公开(公告)日：2013-01-10
申请号：US13176060
申请日：2011-07-05
申请人： Yun-Bae Kim , Seong Soo Joo , Dong Sun Park
发明人： Yun-Bae Kim , Seong Soo Joo , Dong Sun Park
IPC分类号： C12Q1/68 , G01N33/566
CPC分类号： G01N33/6896 , C12Q1/6883 , C12Q2600/158 , G01N2800/2871
摘要： The present invention relates to a method for detecting neuronal injury in a mammalian subject. The biomarker of this invention specifically increases in serum of the mammalian that has neuronal injuries. In addition, the biomarker of this invention permits to identify and predict neuronal injuries.
摘要翻译：本发明涉及一种用于检测哺乳动物受试者的神经元损伤的方法。本发明的生物标志物特异地增加了具有神经元损伤的哺乳动物的血清。此外，本发明的生物标志物允许鉴定和预测神经元损伤。

99. 发明授权

US08303310B2 System for evaluating information competency and method thereof 有权
标题翻译：评估信息能力的系统及其方法
公开(公告)号：US08303310B2
公开(公告)日：2012-11-06
申请号：US11948634
申请日：2007-11-30
申请人： Chui-Young Yoon
发明人： Chui-Young Yoon
IPC分类号： G09B19/00 , G06Q10/00
CPC分类号： G09B19/00 , G06F19/00 , G09B23/28
摘要： An information competency evaluation system and a method thereof are disclosed. The system selects an evaluation group containing an evaluation target from evaluation groups classified by business departments and business position. The system provides evaluation problems of evaluation domains to an evaluation target based on a selected evaluation group, estimates evaluation response received from a terminal of an evaluation target, and estimates EIIC by applying a weight of evaluation domains to a selected evaluation group. The system refers to a core evaluation domain according to EIIC and a selected evaluation group to determine an information competency maturity stage of an evaluation target. The system analyzes information competency of an evaluation target with EIIC and a maturity stage and by business departments and business position to provide the analysis to a terminal. The system analyzes and provides information competency with complex indicators of determining a level of information competency, and provides education information for development of an information competency of evaluation target.
摘要翻译：公开了一种信息能力评估系统及其方法。系统从业务部门和业务职位分类的评估组中选择一个包含评估对象的评估组。该系统基于所选择的评估组，将评估域的评估问题提供给评估目标，估计从评估目标的终端接收到的评价响应，并通过将评估域的权重应用于所选择的评估组来估计EIIC。该系统是指根据EIIC的核心评估领域和选定的评估组，以确定评估目标的信息能力成熟度阶段。系统分析EIIC和成熟期评估对象的信息能力，业务部门和业务情况，对终端进行分析。系统分析和提供信息能力与决定信息能力水平的复杂指标，并提供教育信息，以发展评估目标的信息能力。

100. 发明申请

US20120245791A1 APPARATUS AND METHOD FOR PREDICTING MIXED PROBLEMS WITH VEHICLE 审中-公开
标题翻译：用于预测车辆混合问题的装置和方法
公开(公告)号：US20120245791A1
公开(公告)日：2012-09-27
申请号：US13284780
申请日：2011-10-28
申请人： Un-Il Yun , Shin-Kyung Lee , Hyeon-Il Shin , Gwang-Bum Pyun , Jeong-Woo Lee , Oh-Cheon Kwon , Hyun-Seo Oh , Heung-Mo Ryang
发明人： Un-Il Yun , Shin-Kyung Lee , Hyeon-Il Shin , Gwang-Bum Pyun , Jeong-Woo Lee , Oh-Cheon Kwon , Hyun-Seo Oh , Heung-Mo Ryang
IPC分类号： G06F7/00
CPC分类号： B60W50/0205 , F02D41/1405
摘要： The apparatus includes a data normalization unit, a neural network problem prediction unit, and a transition change prediction unit. The data normalization unit creates normalization transformation values by performing normalization transformation based on threshold value ranges for a plurality of pieces of vehicle network data. The neural network problem prediction unit creates a neural network problem prediction value by predicting a mixed problem with the vehicle using a multi-artificial neural network model, created based on a learning data set related to mixed problems having previously occurred in the vehicle and the normalization transformation values. The transition change prediction unit predicts a change in transition for the mixed problem according to a change in the neural network problem prediction value, by analyzing the neural network problem prediction value and previous neural network problem prediction values previously created in the vehicle.
摘要翻译：该装置包括数据归一化单元，神经网络问题预测单元和过渡变化预测单元。数据归一化单元通过基于多个车辆网络数据的阈值范围执行归一化变换来生成归一化变换值。神经网络问题预测单元通过使用基于与先前在车辆中发生的混合问题相关联的学习数据集创建的多人造神经网络模型来预测与车辆的混合问题来创建神经网络问题预测值，并且归一化转换值。过渡变化预测单元通过分析神经网络问题预测值和先前在车辆中产生的先前的神经网络问题预测值来预测根据神经网络问题预测值的变化的混合问题的转变的变化。

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