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91. 发明授权

US5456698A Pacemaker 失效
标题翻译：起搏器
公开(公告)号：US5456698A
公开(公告)日：1995-10-10
申请号：US158832
申请日：1993-11-23
申请人： James K. Byland , Michael D. DeFranco , William J. Hooper , James M. Sikorski , David L. Thompson
发明人： James K. Byland , Michael D. DeFranco , William J. Hooper , James M. Sikorski , David L. Thompson
IPC分类号： A61N1/375
CPC分类号： A61N1/375 , A61N1/37229 , A61N1/3758
摘要： An enclosure for use in pacemaker as well as other implantable medical devices has a substantially planar lid which is welded to a circumferential flange formed on a deep drawn shield. The shield and lid form a "container" which is encased in a compliant shroud which isolates the welded flange from direct body contact and which enhances the biocompatibility of the entire device. A resilient and compliant shroud material accepts connector module components, integrates seals, provides storage for lead wrap, and provides a simple low cost and reliable method of attaching stimulating leads or other structures required by the medical device.
摘要翻译：用于起搏器和其它可植入医疗装置的外壳具有基本上平坦的盖子，其被焊接到形成在深拉屏蔽上的圆周凸缘。屏蔽罩和盖子形成一个“容器”，其被包裹在顺应的护罩中，其将焊接的凸缘与直接的身体接触隔离，并且增强了整个装置的生物相容性。弹性和柔顺的护罩材料接受连接器模块组件，集成密封件，提供铅封的存储，并提供简单的低成本和可靠的方法来附接刺激引线或医疗设备所需的其他结构。

92. 发明授权

US5391193A Method and apparatus for battery depletion monitoring 失效
标题翻译：电池耗尽监测方法和装置
公开(公告)号：US5391193A
公开(公告)日：1995-02-21
申请号：US14296
申请日：1993-02-05
申请人： David L. Thompson
发明人： David L. Thompson
IPC分类号： A61N1/08 , A61N1/37
CPC分类号： A61N1/08 , A61N1/3708
摘要： A method and apparatus for estimating the remaining capacity of a lithium-iodine battery through the nomographic analysis of two or more measurements of battery impedance. In a preferred embodiment, a pacemaker or other implantable medical device is provided with circuitry for periodically measuring the internal impedance of its battery. Each measurement of impedance is stored along with an indication of when such measurement was made. Nomographic analysis, based upon the rated capacity of the battery and the expected internal impedance at various stages of depletion, allows for two or more time-stamped impedance measurements to serve as the basis for an extrapolation to estimate the remaining service life of the implantable medical device. Nomographic analysis may be performed by circuitry contained in the implanted device itself; in the alternative, periodic impedance measurements may be communicated to external processing circuitry via a telemetry channel.
摘要翻译：通过对电池阻抗的两个或多个测量值的标称分析来估计锂 - 碘电池的剩余容量的方法和装置。在优选实施例中，起搏器或其它可植入医疗装置设置有用于周期性地测量其电池的内部阻抗的电路。阻抗的每个测量结果与进行这种测量的指示一起存储。基于电池的额定容量和不同耗尽阶段的预期内部阻抗的标称分析允许两次或更多次时间戳的阻抗测量值作为外推的基础，以估计可植入医疗器件的剩余使用寿命设备。标称分析可以由植入装置本身包含的电路执行; 在替代方案中，周期性阻抗测量可以经由遥测通道传送到外部处理电路。

93. 发明授权

US5360437A Implantable medical device with flexible hardware platform 失效
标题翻译：植入式医疗器械具有灵活的硬件平台
公开(公告)号：US5360437A
公开(公告)日：1994-11-01
申请号：US149161
申请日：1993-11-08
申请人： David L. Thompson
发明人： David L. Thompson
IPC分类号： A61N1/372 , A61N1/362
CPC分类号： A61N1/37264 , A61N1/37211
摘要： A medical device providing a flexible hardware platform to support alternative therapeutic functions is disclosed. In one embodiment, a microprocessor-based pacemaker incorporates a non-volatile ferroelectric random access read/write memory (FRAM) for storing microprocessor instructions defining a pacing algorithm. Information in the FRAM may be re-written after implant of the pacemaker in a patient via the pacemaker's telemetry link, so that the pacemaker's pacing function may be upgraded or replaced without explant of the pacemaker. The non-volatility of the FRAM ensures that the pacing function is not erased if power to the pacemaker is momentarily interrupted. The flexible hardware platform allows a single type of pacemaker to be implanted in patients with varying cardiac conditions and pacing requirements, thus reducing the inventory requirements of hospitals. The pacing function in pacemakers for patients with progressive or otherwise changing medical conditions can be modified in accordance with the patients' changing needs without invasive procedures. Rewriting of the pacing function is carried out separately from conventional modification of mode selection and parameter value programming. Other information, including parameter data, implant data, patient medical data, and device identification data may also be stored in the FRAM.
摘要翻译：公开了提供灵活硬件平台以支持替代治疗功能的医疗装置。在一个实施例中，基于微处理器的起搏器包括用于存储定义起搏算法的微处理器指令的非易失性铁电随机存取读/写存储器（FRAM）。通过心脏起搏器的遥测连接将起搏器植入患者体内后，FRAM中的信息可能被重新编写，以便可以升高或更换起搏器的起搏功能，而无需起搏器的外植。 FRAM的非挥发性可确保起搏功能暂时中断时起搏功能不会被清除。灵活的硬件平台允许将单一类型的起搏器植入具有不同心脏状况和起搏要求的患者，从而减少医院的库存需求。患有进行性或其他变化的病情的患者的起搏器的起搏功能可以根据病人不断变化的需求进行修改，而无需侵入性手术。起搏功能的重写与常规的模式选择和参数值编程的修改分开进行。其他信息，包括参数数据，植入物数据，患者医疗数据和设备识别数据也可存储在FRAM中。

94. 发明授权

US5314450A Dual channel telemetry for implanted medical device 失效
标题翻译：用于植入医疗器械的双通道遥测
公开(公告)号：US5314450A
公开(公告)日：1994-05-24
申请号：US896641
申请日：1992-06-10
申请人： David L. Thompson
发明人： David L. Thompson
IPC分类号： A61N1/372 , A61N1/00 , G08B23/00 , H04J9/00 , H04L5/04
CPC分类号： A61N1/3727 , A61N1/3708 , A61N1/37211 , A61N1/378 , Y10S128/903
摘要： A method of and apparatus for telemetering both analog and digital data transcutaneously between an implantable medical device and an external receiver, such as between an external programmer and an implantable cardiac pacer. A damped carrier at 175 kilohertz is pulse position modulated by digital data. The data, along with synchronization and identification codes, are positioned into predefined ranges within predefined frames as measured by individual time periods. The data is uniquely identified by the position of a burst of the carrier within the predefined range. An automatically initiated hand shake protocol maintains the link over slight variations in programmer head position with an indicator notifying the operator when repositioning is required. Analog data may be transferred in digital form or alternatively transferred using phase modulation of the carrier bursts. A cyclic redundancy code is used for link error detection.
摘要翻译：一种用于在可植入医疗装置和外部接收器之间经常地模拟模拟和数字数据的方法和装置，诸如在外部编程器和可植入心脏起搏器之间。 175千赫兹的阻尼载波是由数字数据调制的脉冲位置。数据以及同步和识别代码被定位在预定义帧内的预定义范围内，如通过各个时间段所测量的。数据由载体突发在该预定范围内的位置唯一地标识。自动启动的手抖动协议通过在需要重新定位时通知操作者来保持编程器头部位置的轻微变化的连接。模拟数据可以以数字形式传送，或者使用载波突发的相位调制传输。循环冗余码用于链路错误检测。

95. 发明授权

US4494622A Motorcycle power transmission and brake assembly 失效
标题翻译：摩托车动力传动和制动总成
公开(公告)号：US4494622A
公开(公告)日：1985-01-22
申请号：US416370
申请日：1982-09-09
申请人： David L. Thompson
发明人： David L. Thompson
IPC分类号： B62K25/28 , B62L1/00
CPC分类号： B62L1/00 , B62K25/283
摘要： A power transmission and brake assembly for motorcycles and like vehicles wherein a chain driven rear wheel is mounted on a swing arm, is disclosed. An idle sprocket and brake assembly including a first and a second idle sprocket and a brake member such as a brake disk is mounted to rotate about a pivot axle of the swing arm. First and second endless chains interconnect the idle sprocket assembly respectively with an output shaft mounted drive sprocket and a rear wheel sprocket. A brake engaging member, such as a pair of hydraulically actuated brake calipers, is fixedly connected directly or indirectly to the swing arm. The brake engaging member frictionally engages the brake member whenever braking of the chain driven wheel is desired. As a result, a force arises during braking which tends to push the rear wheel downward towards the road surface, and thereby increases the traction of the rear wheel.
摘要翻译：公开了一种用于摩托车和类似车辆的动力传动和制动组件，其中链轮驱动的后轮安装在摆臂上。包括第一和第二惰性链轮和诸如制动盘的制动构件的空转链轮和制动组件安装成围绕摆臂的枢转轴旋转。第一和第二环形链条分别与惰轮链轮组件与输出轴安装的驱动链轮和后轮链轮相互连接。诸如一对液压致动的制动钳的制动器接合构件直接地或间接地固定地连接到摆臂。只要期望制动链条从动轮的制动器接合件摩擦地接合制动件。结果，在制动期间产生力，其倾向于将后轮向下推向路面，从而增加后轮的牵引力。

96. 发明授权

US08706253B2 System and apparatus for controlled activation of acute use medical devices 有权
标题翻译：用于急性用途医疗装置的受控激活的系统和装置
公开(公告)号：US08706253B2
公开(公告)日：2014-04-22
申请号：US13226399
申请日：2011-09-06
申请人： Daniel R. Greeninger , David A. Dinsmoor , Vincent Larik , Rogier Receveur , David L. Thompson
发明人： Daniel R. Greeninger , David A. Dinsmoor , Vincent Larik , Rogier Receveur , David L. Thompson
IPC分类号： A61N1/08
CPC分类号： A61N1/3787 , A61N1/08 , A61N1/378
摘要： An integrated activation system for an implantable medical device (IMD) sharing a power source, the activation system comprising a switching circuit having first and second inputs and having an output coupled to the acute use device, a gating element coupled to the first input and configured to gate power from the power source to the switching circuit, and a sensing element coupled to the second input of the switching circuit. The sensing element is configured to sense an activation condition, enable an operation interval of the switching circuit, and transmit a signal to the switching circuit during the activation condition. The switching circuit is configured to transmit power to the acute use device upon receipt of a pre-determined number of signals from the sensing element.
摘要翻译：一种用于共享电源的可植入医疗装置（IMD）的集成激活系统，所述激活系统包括具有第一和第二输入并且具有耦合到所述急性使用装置的输出的切换电路，耦合到所述第一输入并配置的门控元件从电源到开关电路的栅极电力，以及耦合到开关电路的第二输入的感测元件。感测元件被配置为感测激活条件，启用开关电路的操作间隔，并且在激活条件期间将信号发送到开关电路。开关电路被配置为在接收到来自感测元件的预定数量的信号时将功率传送到急用设备。

97. 发明申请

US20120276854A1 Slot Antenna For An Implantable Device 有权
标题翻译：用于可植入装置的插槽天线
公开(公告)号：US20120276854A1
公开(公告)日：2012-11-01
申请号：US13098279
申请日：2011-04-29
申请人： Himanshu Joshi , David L. Thompson , Jared Brandon Floyd , Eric Y. Chow , Jonathan D. Rowell
发明人： Himanshu Joshi , David L. Thompson , Jared Brandon Floyd , Eric Y. Chow , Jonathan D. Rowell
IPC分类号： H04W88/00 , H01Q13/10 , H02J7/04 , H01P11/00
CPC分类号： A61N1/37229 , A61N1/375 , H01Q1/273 , H01Q1/38 , H01Q1/521 , H01Q7/00 , H01Q9/045 , H01Q13/106 , H01Q21/08 , H01Q21/205 , H01Q21/30 , H02J7/025 , H02J50/10 , H02J50/80 , Y10T29/49016
摘要： An implantable medical device may include a case which houses components of the implantable medical device. The implantable medical device may include an inductive coil coupled to a rechargeable battery. The inductive coil may be operative to inductively couple to an external coil and to transfer energy from the external coil to the rechargeable battery to recharge the rechargeable battery. The implantable medical device may include a cutout formed in the case of the implantable medical device and filled with a dielectric material. The cutout may be operative to reduce eddy currents in the case during recharge of the rechargeable battery. The implantable medical device may include a slot antenna disposed within the case. The slot antenna may be operative to communicate with an external device through the cutout in the case.
摘要翻译：可植入医疗装置可以包括容纳可植入医疗装置的部件的壳体。可植入医疗装置可以包括耦合到可再充电电池的感应线圈。感应线圈可以工作以感应地耦合到外部线圈并且将能量从外部线圈传递到可再充电电池以对可再充电电池再充电。可植入医疗装置可以包括在可植入医疗装置的情况下形成并且填充有电介质材料的切口。在可充电电池的再充电期间，切口可以有效地减少涡流。可植入医疗装置可以包括设置在壳体内的缝隙天线。缝隙天线可以通过外壳中的切口与外部设备通信。

98. 发明申请

US20120116481A1 System and Apparatus for Controlled Activation of Acute Use Medical Devices 有权
标题翻译：控制激活急性用途医疗器械的系统和装置
公开(公告)号：US20120116481A1
公开(公告)日：2012-05-10
申请号：US13226399
申请日：2011-09-06
申请人： Daniel R. Greeninger , David A. Dinsmoor , Vincent Larik , Receveur Rogier , David L. Thompson
发明人： Daniel R. Greeninger , David A. Dinsmoor , Vincent Larik , Receveur Rogier , David L. Thompson
IPC分类号： A61N1/36
CPC分类号： A61N1/3787 , A61N1/08 , A61N1/378
摘要： An integrated activation system for an implantable medical device (IMD) sharing a power source, the activation system comprising a switching circuit having first and second inputs and having an output coupled to the acute use device, a gating element coupled to the first input and configured to gate power from the power source to the switching circuit, and a sensing element coupled to the second input of the switching circuit. The sensing element is configured to sense an activation condition, enable an operation interval of the switching circuit, and transmit a signal to the switching circuit during the activation condition. The switching circuit is configured to transmit power to the acute use device upon receipt of a pre-determined number of signals from the sensing element.
摘要翻译：一种用于共享电源的可植入医疗装置（IMD）的集成激活系统，所述激活系统包括具有第一和第二输入并且具有耦合到所述急性使用装置的输出的切换电路，耦合到所述第一输入并配置的门控元件从电源到开关电路的栅极电力，以及耦合到开关电路的第二输入的感测元件。感测元件被配置为感测激活条件，启用开关电路的操作间隔，并且在激活条件期间将信号发送到开关电路。开关电路被配置为在接收到来自感测元件的预定数量的信号时将功率传送到急用设备。

99. 发明授权

US08014872B2 System and apparatus for controlled activation of acute use medical devices 有权
标题翻译：用于急性用途医疗装置的受控激活的系统和装置
公开(公告)号：US08014872B2
公开(公告)日：2011-09-06
申请号：US11343354
申请日：2006-01-31
申请人： Daniel R. Greeninger , David A. Dinsmoor , Vincent Larik , Receveur Rogier , David L. Thompson
发明人： Daniel R. Greeninger , David A. Dinsmoor , Vincent Larik , Receveur Rogier , David L. Thompson
IPC分类号： A61N1/08
CPC分类号： A61N1/3787 , A61N1/08 , A61N1/378
摘要： An integrated activation system for an implantable medical device (IMD) sharing a power source, the activation system comprising a switching circuit having first and second inputs and having an output coupled to the acute use device, a gating element coupled to the first input and configured to gate power from the power source to the switching circuit, and a sensing element coupled to the second input of the switching circuit. The sensing element is configured to sense an activation condition, enable an operation interval of the switching circuit, and transmit a signal to the switching circuit during the activation condition. The switching circuit is configured to transmit power to the acute use device upon receipt of a pre-determined number of signals from the sensing element.
摘要翻译：一种用于共享电源的可植入医疗装置（IMD）的集成激活系统，所述激活系统包括具有第一和第二输入并且具有耦合到所述急性使用装置的输出的切换电路，耦合到所述第一输入并配置的门控元件从电源到开关电路的栅极电力，以及耦合到开关电路的第二输入的感测元件。感测元件被配置为感测激活条件，启用开关电路的操作间隔，并且在激活条件期间将信号发送到开关电路。开关电路被配置为在接收到来自感测元件的预定数量的信号时将功率传送到急用设备。

100. 发明授权

US07239916B2 Method and apparatus for automatic implantable medical lead recognition and configuration 有权
标题翻译：用于自动植入式医疗导线识别和配置的方法和装置
公开(公告)号：US07239916B2
公开(公告)日：2007-07-03
申请号：US10714123
申请日：2003-11-14
申请人： David L. Thompson , Steven D. Goedeke , Gregory J. Haubrich , Ryan Cobian , Eric Bonde , John L. Sommer , Jonathan Werder , Nels Nerison , Eric V. Blaha
发明人： David L. Thompson , Steven D. Goedeke , Gregory J. Haubrich , Ryan Cobian , Eric Bonde , John L. Sommer , Jonathan Werder , Nels Nerison , Eric V. Blaha
IPC分类号： A61N1/362
CPC分类号： A61N1/37252 , A61B5/0031 , A61B2560/0219 , A61N1/025 , A61N1/05 , A61N1/37223 , A61N1/3752 , A61N2001/0585
摘要： An automated identification and configuration system for use with an implantable medical device (IMD) is disclosed. The system includes a first communication circuit that is attached to, or otherwise carried by, a detachable component associated with the IMD such as a medical lead. The communication circuit stores data such as model numbers, serial numbers, technical data, and/or calibration information that describes the additional component. This information may be transferred by the first communications circuit to a second communications circuit that is external to the additional component. This transferred data can be used to automatically configure the internal circuitry and connection functions of the IMD to properly interface with, and support, the additional component. For example, the data can be used to automatically adjust amplifier gains or other sensor circuitry, or to configure a connector block to properly couple to the component. The data may further be entered into a patient record on an external programmer, or may be transferred to a central storage location to be generally accessible to health care providers. In one embodiment, the first communication circuit is a passive RF transponder. This first communication circuit may include a receiver as well as a transmitter to allow the circuit to programmably receive data at the time of component manufacture.
摘要翻译：公开了一种用于可植入医疗装置（IMD）的自动识别和配置系统。该系统包括第一通信电路，其连接到与IMD相关联的可拆卸部件（例如医疗引线）或由其携带。通信电路存储诸如型号，序列号，技术数据和/或描述附加组件的校准信息的数据。该信息可以由第一通信电路传送到附加组件外部的第二通信电路。该传输的数据可用于自动配置IMD的内部电路和连接功能，以正确地连接和支持附加组件。例如，数据可用于自动调整放大器增益或其他传感器电路，或配置连接器块以正确耦合到组件。数据可以进一步输入到外部编程器上的病人记录中，或者可以被传送到中央存储位置，以便卫生保健提供者通常可访问。在一个实施例中，第一通信电路是无源RF应答器。该第一通信电路可以包括接收器以及发射器，以允许电路在组件制造时可编程地接收数据。

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