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    • 92. 发明授权
    • Perforator for imaging apparatus, and paper handler provided therewith
    • 用于成像设备的穿孔器和与其一起提供的纸张处理器
    • US07461578B2
    • 2008-12-09
    • US10901049
    • 2004-07-29
    • Masahiro TamuraNobuyoshi Suzuki
    • Masahiro TamuraNobuyoshi Suzuki
    • B26D7/18G03G15/00
    • B26D7/18B26D2007/0018B26F1/02Y10T83/2174Y10T83/2179Y10T83/2216Y10T83/222Y10T83/9416Y10T83/9423Y10T83/944
    • A perforator includes a perforating unit, a chad recovery/delivery unit, a chad storage unit, a chad guiding unit, and a shielding unit. The perforating unit perforates a sheet-shaped recording medium. The chad recovery/delivery unit delivers a chad perforated by the perforating unit to the chad storage unit via discharge channels in the chad guiding unit. The chad storage unit stores the delivered chad. The shielding unit includes a shielding body and a shielding face fixed on an end thereof. The shielding unit releases a shielding against the discharge channels to discharge the chad though an opening in an interior of the shielding body to the chad storage unit when the shielding unit is in a first position. When the shielding unit is in a second position, the shielding face blocks the discharge channels to prevent the chad from being discharged to the chad storage unit.
    • 穿孔器包括穿孔单元,乍得回收/传送单元,ch ad存储单元,ch子引导单元和屏蔽单元。 穿孔单元对片状记录介质进行穿孔。 ch ad recovery recovery delivery delivery delivery ch ch ch ch ch ch ch ch。。。。。。。。。。。。。。。。。。 chad存储单元存储交付的ch。。 屏蔽单元包括屏蔽体和固定在其一端的屏蔽面。 当屏蔽单元处于第一位置时,屏蔽单元通过屏蔽体的内部的开口释放到排泄通道的屏蔽,以排出乍得。 当屏蔽单元处于第二位置时,屏蔽面阻止排出通道,以防止ch being被排出到ch ad存储单元。
    • 100. 发明申请
    • Angiogenesis inhibitor
    • 血管生成抑制剂
    • US20070043078A1
    • 2007-02-22
    • US10574972
    • 2004-10-08
    • Takeshi DoiMasahiro Tamura
    • Takeshi DoiMasahiro Tamura
    • A61K31/4545
    • A61K31/4468A61K31/444A61K31/4545C07D401/14
    • The present invention relates to a prophylactic or therapeutic agent against a disease or pathological condition caused by angiogenesis, comprising, as an active ingredient, a cyclic amine compound represented by the general formula (1): wherein R1, R2, and R3 each independently represent a hydrogen atom, a halogen atom, a hydroxy group, an alkyl group, a halogen-substituted alkyl group, an alkoxy group, an alkylthio group, a carboxyl group, an alkoxycarbonyl group, or an alkanoyl group; W1 and W2 each independently represent N or CH; X represents O, NR4, CONR4, or NR4CO; R4 represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted heteroaryl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted heteroaralkyl group; and l, m, and n each represent a number of 0 or 1, or a salt thereof, or a solvate thereof.
    • 本发明涉及由血管发生引起的疾病或病理状况的预防或治疗剂,其包含作为活性成分的通式(1)表示的环胺化合物:其中R 1, R 2,R 3和R 3各自独立地表示氢原子,卤素原子,羟基,烷基,卤素取代的烷基,烷氧基 ,烷硫基,羧基,烷氧基羰基或烷酰基; W 1和W 2各自独立地表示N或CH; X表示O,NR 4,CONR 4或NR 4 CO; R 4表示氢原子,烷基,烯基,炔基,取代或未取代的芳基,取代或未取代的杂芳基,取代或未取代的芳烷基或取代的 或未取代的杂芳烷基; 和l,m和n各自表示0或1的数,或其盐或其溶剂合物。