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91. 发明授权

US09012632B2 Method for rapidly methylating heteroaromatic arene and method for producing tracer for use in PET 有权
标题翻译：用于快速甲基化杂芳族芳烃的方法和用于生产用于PET的示踪剂的方法
公开(公告)号：US09012632B2
公开(公告)日：2015-04-21
申请号：US13142207
申请日：2009-12-25
申请人： Masaaki Suzuki , Hisashi Doi , Hiroko Koyama
发明人： Masaaki Suzuki , Hisashi Doi , Hiroko Koyama
IPC分类号： C07D221/00 , C07D217/02 , C07D333/08 , C07D307/36 , C07D231/12 , C07D237/08 , C07D239/26 , C07D213/127
CPC分类号： C07D213/127 , C07D217/02 , C07D231/12 , C07D237/08 , C07D239/26 , C07D307/36 , C07D333/08
摘要： Provided is a method whereby a heteroaromatic ring aryl can be very rapidly methylated at a high yield. In an N-alkyl-2-pyrrolidinone, a heteroaromatic ring aryltrialkylstannan is cross-coupled with methyl iodide in the presence of a palladium complex, a phosphine ligand, a cuprous halide, a carbonic acid salt and/or an alkali metal fluoride to thereby rapidly methylate the heteroaromatic ring aryl. (Formula shows a case wherein the heteroaromatic ring aryl is a pyridyl group.)
摘要翻译：提供了一种方法，其中杂芳环芳基可以以高产率非常快速地甲基化。在N-烷基-2-吡咯烷酮中，在钯络合物，膦配体，卤化亚铜，碳酸盐和/或碱金属氟化物的存在下，将杂芳环芳基三烷基锡丹与甲基碘交联，从而快速甲基化杂芳环芳基。（式中，杂芳香环是吡啶基的情况）

92. 发明授权

US08778298B2 Isotope labeled 2-arylpropionic acid compounds and process for production of same, and molecular probe for positron emission tomography and method for imaging of cyclooxygenase and the like using same 失效
标题翻译：同位素标记的2-芳基丙酸化合物及其制备方法，用于正电子发射断层摄影的分子探针和使用其的环氧合酶等的成像方法
公开(公告)号：US08778298B2
公开(公告)日：2014-07-15
申请号：US13387753
申请日：2010-07-29
申请人： Misato Takashima , Miho Shukuri , Miki Goto , Hisashi Doi , Hirotaka Onoe , Masaaki Suzuki , Yasuyoshi Watanabe
发明人： Misato Takashima , Miho Shukuri , Miki Goto , Hisashi Doi , Hirotaka Onoe , Masaaki Suzuki , Yasuyoshi Watanabe
IPC分类号： A61K51/00 , A61M36/14 , A61K31/192 , A61K49/04 , A61K51/04
CPC分类号： A61K31/192 , A61K49/0433 , A61K51/04 , A61K51/0402 , C07B59/001 , C07B2200/05 , C07B2200/07 , C07C57/30 , C07C57/58 , C07C59/64 , C07C59/68 , C07C59/84 , C07C59/86 , C07C69/612 , C07C69/65 , C07C69/734 , C07C69/736 , C07C69/738 , C07C2601/08
摘要： Disclosed are: labeled NSAIDs compounds which can be produced within a short time, can be used suitably for a PET method, and enable the imaging of cyclooxygenase-2; and a process for producing the labeled NSAIDs compounds. Specifically disclosed are isotope-labeled 2-arylpropionic acid compounds, each of which is a compound represented by general formula (1) (wherein Ar represents an aryl group which may have a substituent; R1 represents anyone selected from 11CH3, CH218F and CF218F; and R2 represents a hydrogen atom, or an alkyl group which may have a branch, wherein a compound wherein Ar is a benzene ring, R1 is 11CH3, and R2 is a hydrogen atom is excluded), or a pharmaceutically acceptable salt, hydrate, solvate or prodrug thereof.
摘要翻译：公开的是：可以在短时间内生产的标记的NSAIDs化合物可以适用于PET方法，并且能够进行环氧合酶-2的成像; 以及生产标记的NSAIDs化合物的方法。具体公开的是同位素标记的2-芳基丙酸化合物，其各自为通式（1）表示的化合物（其中Ar表示可具有取代基的芳基; R1表示选自11CH3，CH218F和CF218F的任何一种; R2表示氢原子或可具有支链的烷基，其中Ar为苯环，R1为11CH3，R2为氢原子的化合物除外），或其药学上可接受的盐，水合物，溶剂合物或前药。

93. 发明授权

US08767114B2 Solid-state imaging element and imaging device 有权
标题翻译：固态成像元件和成像装置
公开(公告)号：US08767114B2
公开(公告)日：2014-07-01
申请号：US13502408
申请日：2011-04-22
申请人： Masao Hiramoto , Masaaki Suzuki
发明人： Masao Hiramoto , Masaaki Suzuki
IPC分类号： H04N9/07
CPC分类号： H01L27/14621 , H01L27/14627 , H01L27/14629 , H04N9/045
摘要： The solid-state image sensor of the present invention includes an array of photosensitive cells, an array 100 of dispersing elements, and an array 300 of color filters. The photosensitive cell array 200 has a number of unit blocks 40, each of which includes photosensitive cells 2a and 2b. The dispersing element array 100 includes a dispersing element 1a, which makes all of incoming light (W) but a light ray falling within a first wavelength range incident on the first photosensitive cell 2a and which also makes at least a part of the light ray falling within the first wavelength range incident on the second photosensitive cell 2b. A color filter 3a that either absorbs or reflects the light ray falling within the first wavelength range is arranged between the photosensitive cell 2a and the dispersing element 1a.
摘要翻译：本发明的固态图像传感器包括感光单元阵列，分散元件阵列100和滤色器阵列300。感光单元阵列200具有多个单位块40，每个单元块40包括感光单元2a和2b。分散元件阵列100包括分散元件1a，其使入射光（W）全部入射到第一感光单元2a上的第一波长范围内的光线，并且还使至少一部分光线落下在入射到第二感光单元2b上的第一波长范围内。吸收或反射落在第一波长范围内的光线的滤色器3a布置在感光单元2a和分散元件1a之间。

94. 发明授权

US08680260B2 18F-labeled azide compound, reagent for 18F-labeling and method for 18F-labeling of alkyne compound using same 失效
标题翻译： 18F标记的叠氮化合物，用于18F标记的试剂和使用其的18E-标记炔化合物的方法
公开(公告)号：US08680260B2
公开(公告)日：2014-03-25
申请号：US13320421
申请日：2010-05-14
申请人： Yasuyoshi Watanabe , Masaaki Suzuki , Hisashi Doi , Takeshi Kuboyama , Satoshi Obika , Takeshi Imanishi
发明人： Yasuyoshi Watanabe , Masaaki Suzuki , Hisashi Doi , Takeshi Kuboyama , Satoshi Obika , Takeshi Imanishi
IPC分类号： C07H21/00
CPC分类号： A61K51/0453 , A61K51/0491 , C07B59/005 , C07B2200/05 , C07C247/16 , C07D249/06
摘要： The present invention provides an 18F-labeled azide compound usable in the Huisgen reaction which enables 18F-labeling although only a small quantity of alkyne compound is available as a counterpart substrate, more specifically the 18F-labeled azide compound enabling the PET to be applied to peptides or oligonucleotides and enabling the 18F-labeling of any sites of oligonucleotide other than the 5′ end or 3′ end thereof, a reagent for 18F-labeling, and a method for 18F-labeling of an alkyne compound using the same.
摘要翻译：本发明提供了可用于Huisgen反应的18F标记的叠氮化合物，其能够进行18F标记，尽管只有少量的炔化合物可用作对应的基质，更具体地说，18F-标记的叠氮化合物使PET能够应用于肽或寡核苷酸，并且能够进行除了5'末端或3'末端以外的寡核苷酸的任何位点的18F标记，用于18F标记的试剂，以及使用其的18E-标记的炔化合物的方法。

95. 发明申请

US20130330607A1 ELECTROLYTIC SOLUTION AND LITHIUM-ION SECONDARY BATTERY 审中-公开
标题翻译：电解液和锂离子二次电池
公开(公告)号：US20130330607A1
公开(公告)日：2013-12-12
申请号：US13985250
申请日：2012-02-16
申请人： Kayo Mizuno , Keiichi Hayashi , Toshiki Inoue , Osamu Ohmori , Takayuki Hirose , Yusuke Yamamoto , Kohei Mase , Masaaki Suzuki
发明人： Kayo Mizuno , Keiichi Hayashi , Toshiki Inoue , Osamu Ohmori , Takayuki Hirose , Yusuke Yamamoto , Kohei Mase , Masaaki Suzuki
IPC分类号： H01M10/0567 , H01M10/0525
CPC分类号： H01M10/0525 , H01M4/386 , H01M4/505 , H01M10/0567 , H01M10/4235 , H01M2220/20 , Y02E60/122
摘要： In a lithium-ion secondary battery using a positive-electrode active material that includes a lithium-manganese-based oxide which includes a lithium (Li) element and a tetravalent manganese (Mn) element and whose crystal structure belongs to a layered rock-salt structure, adding a compound being selected from the group consisting of Compounds (a) through (i) into the electrolytic solution leads to the following: degradations due to oxidation-reduction decompositions of the electrolytic solution, and so on, are inhibited; and not only the shelf or storage capacity and recovered capacity upgrade in the case of being stored at high temperatures, but also the rise of internal resistance is inhibited.
摘要翻译：在使用包括锂（Li）元素和四价锰（Mn）元素并且其晶体结构属于层状岩盐的锂锰系氧化物的正极活性物质的锂离子二次电池中，结构，将从化合物（a）〜（i）中选择的化合物加入到电解液中导致以下结果：由于电解液的氧化还原分解引起的劣化等被抑制; 而且在高温储存的情况下，不仅架设或储存能力和回收能力提升，而且内阻的上升也受到抑制。

96. 发明申请

US20130059179A1 BIPOLAR SECONDARY BATTERY 有权
标题翻译：双极二次电池
公开(公告)号：US20130059179A1
公开(公告)日：2013-03-07
申请号：US13698173
申请日：2011-05-17
申请人： Kenji Hosaka , Shiho Inoue , Masaaki Suzuki , Kazuki Miyatake
发明人： Kenji Hosaka , Shiho Inoue , Masaaki Suzuki , Kazuki Miyatake
IPC分类号： H01M2/00
CPC分类号： H01M10/0418 , H01M2/0207 , H01M2/266 , H01M2/34 , H01M2/345 , H01M10/0585
摘要： A battery main body housed in a case comprises one laminated body composed of a plurality of bipolar electrodes laminated with an electrolyte layer therebetween or comprises a plurality of laminated bodies connected in series. A positive electrode current collecting plate and a negative electrode current collecting plate each having one surface joined to the inner peripheral surface of the case and the other surface joined to one end of the battery main body respectively extend to the outside of the case. By providing a cutoff mechanism for cutting off an electrical connection between the positive electrode current collecting plate and the negative electrode current collecting plate via the battery main body according to an expansion deformation of the case, a current path in a bipolar secondary battery is interrupted when the short-circuit current occurs, thereby protecting the bipolar secondary battery from a short-circuit current.
摘要翻译：容纳在壳体中的电池主体包括由层叠有电解质层的多个双极电极组成的一个层叠体，或者包括串联连接的多个层叠体。每个具有接合到壳体的内周面的一个表面和与电池主体的一端接合的另一个表面的正极集电板和负极集电板分别延伸到壳体的外部。通过根据壳体的膨胀变形提供切断机构，通过电池主体切断正极集电板和负极集电板之间的电连接，双极二次电池的电流通路被中断，发生短路电流，从而保护双极二次电池不受短路电流的影响。

97. 发明授权

US08288604B2 Method of rapid methylation, kit for preparing PET tracer and method of producing PET tracer 有权
标题翻译：快速甲基化方法，制备PET示踪剂的试剂盒和生产PET示踪剂的方法
公开(公告)号：US08288604B2
公开(公告)日：2012-10-16
申请号：US12438711
申请日：2007-08-24
申请人： Masaaki Suzuki , Hisashi Doi , Hideo Tsukada
发明人： Masaaki Suzuki , Hisashi Doi , Hideo Tsukada
IPC分类号： C07C2/60 , C07C2/68
CPC分类号： C07B59/001 , C07B37/04 , C07B59/00 , C07B2200/05 , C07C1/321 , C07C17/263 , C07C29/32 , C07C41/30 , C07C67/343 , C07C205/06 , C07C2531/24 , C07C2601/16 , C07C25/13 , C07C22/08 , C07C33/03 , C07C69/76 , C07C43/205
摘要： A method of rapid methylation of an aromatic compound or an alkenyl compound, which is capable of obtaining an aromatic compound or an alkenyl compound labeled with a methyl group or a fluoromethyl group under a mild condition rapidly in high yield using an organic boron compound whose toxicity is not so high as a substrate. A kit for preparing a PET tracer and a method of producing a PET tracer can be practiced using the rapid methylation method. In an aprotic polar solvent, methyl iodide or X—CH2F (wherein X is a functional group which can be easily released as an anion), and an organic boron compound in which an aromatic ring or an alkenyl group is attached to boron are subjected to cross-coupling in the presence of a palladium(0) complex, a phosphine ligand, and a base.
摘要翻译：芳族化合物或链烯基化合物的快速甲基化方法，其能够使用有机硼化合物以高收率快速地获得芳香族化合物或用甲基或氟甲基标记的烯基化合物，所述有机硼化合物的毒性不如底物那么高。用于制备PET示踪剂的试剂盒和生产PET示踪剂的方法可以使用快速甲基化方法来实施。在非质子极性溶剂中，甲基碘或X-CH 2 F（其中X是可以容易地作为阴离子释放的官能团）和其中将芳环或烯基连接到硼上的有机硼化合物进行在钯（0）络合物，膦配体和碱的存在下交联。

98. 发明申请

US20120182453A1 SOLID-STATE IMAGE CAPTURING ELEMENT, IMAGE CAPTURING DEVICE AND SIGNAL PROCESSING METHOD 有权
标题翻译：固态图像捕获元件，图像捕获器件和信号处理方法
公开(公告)号：US20120182453A1
公开(公告)日：2012-07-19
申请号：US13498598
申请日：2011-04-22
申请人： Masao Hiramoto , Yusuke Monobe , Yoshiaki Sugitani , Masaaki Suzuki
发明人： Masao Hiramoto , Yusuke Monobe , Yoshiaki Sugitani , Masaaki Suzuki
IPC分类号： H04N9/07 , H04N9/04 , H04N3/14 , H01L27/146
CPC分类号： H01L27/14625 , H01L27/14621 , H01L27/14645 , H04N9/045 , H04N2209/047
摘要： The solid-state image sensor 10 includes an array of photosensitive cells and an array 100 of dispersing elements. The photosensitive cell array is comprised of unit blocks 40, each including four photosensitive cells 2a, 2b, 2c and 2d. The dispersing element array 100 makes light, obtained by subtracting a light ray with a first color component C1 from the incoming light W and adding a light ray with a second color component C2 to the remainder, incident on the first photosensitive cell 2a, also makes light, obtained by subtracting the light ray with the second color component C1 from the incoming light W and adding the light ray with the first color component C1 to the remainder, incident on the second photosensitive cell 2b, further makes light, obtained by subtracting the light rays with the first and second color components C1+C2 from the incoming light W, incident on the third photosensitive cell 2c, and further makes light, obtained by adding the light rays with the first and second color components C1+C2 to the incoming light W, incident on the fourth photosensitive cell 2d.
摘要翻译：固态图像传感器10包括感光单元阵列和分散元件阵列100。感光单元阵列由单元块40组成，每个单元块40包括四个感光单元2a，2b，2c和2d。分散元件阵列100通过从入射光W减去具有第一颜色成分C1的光线并将入射到第一感光单元2a上的剩余部分中的第二颜色分量C2的光线加入而获得的光也使得通过从入射光W减去具有第二颜色分量C1的光线并将入射到第二感光单元2b上的第一颜色分量C1的光线添加到余数而获得的光进一步使得通过减去来自入射光W的第一和第二颜色分量C1 + C2的光线入射到第三感光单元2c上，并且进一步使通过将第一和第二颜色分量C1 + C2的光线与入射入射到第四感光单元2d上的光W。

99. 发明授权

US08220940B2 Antiglare film, antireflection film, polarizing plate and image display device 有权
标题翻译：防斜纹薄膜，防反射膜，偏振片和图像显示装置
公开(公告)号：US08220940B2
公开(公告)日：2012-07-17
申请号：US12551965
申请日：2009-09-01
申请人： Tetsuya Asakura , Shinya Kato , Masaaki Suzuki
发明人： Tetsuya Asakura , Shinya Kato , Masaaki Suzuki
IPC分类号： G02B27/00
CPC分类号： G02B5/0278 , G02B5/0226
摘要： An antiglare film is provided, the antiglare film including: a transparent support; and an antiglare layer, wherein the antiglare layer contains a light-transmitting resin particle, a light-transmitting resin and a copolymerization product having an amine value of 1 to 30 mgKOH/g, and the average particle diameter of the light-transmitting resin particle is from 6 to 20 μm.
摘要翻译：提供防眩膜，防眩膜包括：透明支撑体; 防眩层，其中防眩光层含有透光性树脂粒子，透光性树脂和胺值为1〜30mgKOH / g的共聚合物，透光性树脂粒子的平均粒径为6〜20μm。

100. 发明申请

US20110234869A1 SOLID-STATE IMAGE PICKUP DEVICE AND IMAGE PICKUP APPARATUS 有权
标题翻译：固态图像拾取装置和图像拾取装置
公开(公告)号：US20110234869A1
公开(公告)日：2011-09-29
申请号：US13132690
申请日：2010-09-24
申请人： Masao Hiramoto , Masayuki Misaki , Teruyuki Takizawa , Masaaki Suzuki
发明人： Masao Hiramoto , Masayuki Misaki , Teruyuki Takizawa , Masaaki Suzuki
IPC分类号： H04N5/335
CPC分类号： H04N5/374 , H01L27/14621 , H01L27/14627 , H01L27/1464 , H04N5/2253 , H04N5/2254 , H04N5/2258
摘要： A solid-state image sensor according to the present invention includes: a semiconductor layer (100 with first and second surfaces (100a, 100b), the second surface (100b) being opposite to the first surface (100a); a plurality of photosensitive cells (1a, 1b, etc.), which are arranged two-dimensionally in the semiconductor layer (100) between the first and second surfaces thereof (100a, 100b); a first array (200) of micro condenser lenses, which are arranged on the same side as the first surface (100a) to focus incoming light onto a first group of photosensitive cells that are included in those photosensitive cells; and a second array (300) of micro condenser lenses, which are arranged on the same side as the second surface (100b) to focus incoming light onto a second group of photosensitive cells that are also included in those photosensitive cells but that are different from the first group of photosensitive cells.
摘要翻译：根据本发明的固态图像传感器包括：半导体层（100具有第一和第二表面（100a，100b），第二表面（100b）与第一表面（100a）相对;多个感光单元（100a，100b）在半导体层（100）中二维布置的第一阵列（1a，1b等）;微聚焦透镜的第一阵列（200），布置在与第一表面（100a）相同的一侧，以将入射光聚焦到包含在那些感光单元中的第一组感光单元上;以及微聚焦透镜的第二阵列（300），其布置在与第二表面（100b）将入射光聚焦到第二组感光细胞上，所述第二组感光细胞也包括在那些感光细胞中但不同于第一组感光细胞。

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