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91. 发明申请

US20130197567A1 CLOT ENGAGEMENT AND REMOVAL SYSTEM 有权
公开(公告)号：US20130197567A1
公开(公告)日：2013-08-01
申请号：US13823048
申请日：2011-10-21
申请人： Eamon Brady , Michael Gilvarry , Mahmood K. Razavi , David Vale
发明人： Eamon Brady , Michael Gilvarry , Mahmood K. Razavi , David Vale
IPC分类号： A61B17/221
CPC分类号： A61B17/221 , A61B2017/22034 , A61B2017/22094 , A61B2017/2212 , A61B2017/2217
摘要： A clot retrieval apparatus 1 comprises a clot engaging device 2 and a capture basket 3. The clot engaging device 2 has a collapsed delivery configuration and an expanded deployment configuration. The clot engaging device has a proximal end and a distal end and an elongate body between the proximal end and the distal end. The capture basket 3 has a collapsed delivery configuration and an expanded deployment configuration. The capture basket 3 has a proximal mouth which is open when the capture basket 3 is in the deployment configuration. The clot engaging device 2 is axially movable relative to the capture basket for capture of a clot.

92. 发明授权

US08123778B2 Embolic protection system 有权
标题翻译：栓塞保护系统
公开(公告)号：US08123778B2
公开(公告)日：2012-02-28
申请号：US12259700
申请日：2008-10-28
申请人： Eamon Brady , Gary Fahey , Brendan Casey , Ann Marie Cannon , David Vale , Martin Keegan
发明人： Eamon Brady , Gary Fahey , Brendan Casey , Ann Marie Cannon , David Vale , Martin Keegan
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2/0095 , A61F2/013 , A61F2002/011 , A61F2230/0006 , A61F2230/0008
摘要： An embolic protection system comprises an embolic protection filter 1 having a collapsed delivery configuration and an expanded deployed configuration. The filter 1 is housed in the collapsed configuration in a reception space of a delivery catheter 20. The delivery catheter 20 containing the filter 1 is housed in a sealed sterile pouch 35. The filter 1 may be coated with a non-thrombogenic coating and an adhesion preventer 9 such as a silicon gel is used to substantially prevent adhesion of adjacent folds of the filter 1 when the filter is in the collapsed configuration in the delivery catheter 20.
摘要翻译：栓塞保护系统包括具有折叠输送配置和扩展展开配置的栓塞保护过滤器1。过滤器1在输送导管20的接收空间中收纳在收缩构型中。包含过滤器1的输送导管20容纳在密封的无菌袋35中。过滤器1可以涂覆有非致血性涂层和当过滤器处于输送导管20中的折叠构造时，使用诸如硅胶的粘合防止剂9基本上防止过滤器1的相邻褶皱的粘附。

93. 发明申请

US20110054516A1 EMBOLIC PROTECTION METHOD 审中-公开
标题翻译：嵌入式保护方法
公开(公告)号：US20110054516A1
公开(公告)日：2011-03-03
申请号：US12941473
申请日：2010-11-08
申请人： Martin Keegan , Eamon Brady , Brendan Casey , David Vale , John Neilan , Morgan Tierney
发明人： Martin Keegan , Eamon Brady , Brendan Casey , David Vale , John Neilan , Morgan Tierney
IPC分类号： A61F2/01
CPC分类号： A61F2/0095 , A61B17/221 , A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2002/9522 , A61F2230/0006 , A61F2230/0067
摘要： An embolic protection filter for deployment in a vasculature, the filter having an inlet end and an outlet end, the inlet end having one or more inlet openings sized to allow blood and embolic material enter the filter, and the outlet end of the filter having a plurality of outlet openings sized to allow through passage of blood but to retain undesired embolic material within the filter. The filter is movable between a collapsed configuration for movement through a vasculature, and an outwardly extended configuration for deployment in a vasculature. The filter at least in the collapsed configuration was a guidewire lumen defined at least partially therethrough for passing the filter over a guidewire. The guidewire lumen is defined by a lumen-defining member which is spaced proximally of the distal end of the filter.
摘要翻译：一种用于部署在脉管系统中的栓塞保护过滤器，所述过滤器具有入口端和出口端，所述入口端具有一个或多个入口开口，其尺寸设计成允许血液和栓塞物质进入过滤器，并且所述过滤器的出口端具有多个出口开口尺寸允许通过血液通过，但是将不期望的栓塞材料保持在过滤器内。过滤器可在折叠构型之间移动，以便通过脉管系统移动，以及用于部署在脉管系统中的向外延伸的配置。至少在折叠构造中的过滤器是至少部分地穿过其中的导丝腔，用于使过滤器穿过导丝。导丝管腔由位于过滤器的远端的近端间隔开的内腔限定构件限定。

94. 发明申请

US20100331952A1 METHOD FOR FILTERING EMBOLIC MATERIAL 审中-公开
标题翻译：过滤材料的方法
公开(公告)号：US20100331952A1
公开(公告)日：2010-12-30
申请号：US12875161
申请日：2010-09-03
申请人： Brendan CASEY , John Neilan , Gary Fahey , Michael Gilvarry , Eamon Brady , David Vale , Steven Horan , Ronald Kelly , Gerard McCaffrey
发明人： Brendan CASEY , John Neilan , Gary Fahey , Michael Gilvarry , Eamon Brady , David Vale , Steven Horan , Ronald Kelly , Gerard McCaffrey
IPC分类号： A61B17/22 , A61F2/84
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要： The method comprises the steps of advancing a guidewire from a first intermediate location to a further intermediate location which is proximal of the treatment location and, subsequently, advancing a medical device over the guidewire toward the further intermediate location. The method may comprise repeating these steps for additional intermediate locations. In one case the treatment location is in the carotid artery. The treatment location may be at or adjacent to the carotid bifurcation. An intermediate location may be at or adjacent to the aortic arch. An intermediate location may be at or adjacent to the carotid take-off. The medical device may be delivered over the guidewire using a delivery catheter. The delivery catheter and the medical device may be advanced through the vasculature without the use of a guide catheter.
摘要翻译：该方法包括以下步骤：将导丝从第一中间位置推进到位于治疗位置附近的另外的中间位置，并且随后将医疗装置推过导丝朝向另外的中间位置。该方法可以包括对于另外的中间位置重复这些步骤。在一种情况下，治疗位置在颈动脉中。治疗位置可以在颈动脉分叉处或其附近。中间位置可以在主动脉弓处或邻近主动脉弓。中间位置可以在颈动脉起搏处或邻近。医疗装置可以使用输送导管在导丝上传送。输送导管和医疗装置可以通过脉管系统而不使用导向导管。

95. 发明申请

US20090112127A1 NITINOL GUIDEWIRE 审中-公开
公开(公告)号：US20090112127A1
公开(公告)日：2009-04-30
申请号：US11925829
申请日：2007-10-27
申请人： Karl KEATING , Eamon Brady , David Vale , Marc Gianotti , John Neilan
发明人： Karl KEATING , Eamon Brady , David Vale , Marc Gianotti , John Neilan
IPC分类号： A61M25/01
CPC分类号： A61M25/09 , A61M2025/09075 , A61M2025/09083 , A61M2025/09108 , A61M2025/09141 , A61M2025/09175
摘要： A medical guidewire (1) suitable for advancement through a vasculature comprises a core element (2) extending along the length of the guidewire (1), a first coil (6), and a distal end cap (7). The core element (2) comprises a proximal portion (3), an intermediate portion (4), and a distal portion (5). The distal portion (5) is plastically deformable to facilitate steering of the guidewire (1). The first coil (6) is located radially outwardly of the core element (2). The first coil (6) extends along the distal portion (5) and part of the intermediate portion (4).
摘要翻译：适于通过脉管系统前进的医用导线（1）包括沿导丝（1）的长度延伸的芯元件（2），第一线圈（6）和远端盖（7）。芯元件（2）包括近端部分（3），中间部分（4）和远端部分（5）。远端部分（5）是塑性变形的，以便于导丝（1）的转向。第一线圈（6）位于芯元件（2）的径向外侧。第一线圈（6）沿着远端部分（5）和中间部分（4）的一部分延伸。

96. 发明申请

US20070233180A1 SUPPORT FRAME FOR AN EMBOLIC PROTECTION DEVICE 有权
标题翻译：支撑框架用于插入式保护装置
公开(公告)号：US20070233180A1
公开(公告)日：2007-10-04
申请号：US11762259
申请日：2007-06-13
申请人： Eamon Brady , David Vale , Ronald Kellly , John Neilan , Steven Horan , Gerald Rabitte , Gerry McCaffrey
发明人： Eamon Brady , David Vale , Ronald Kellly , John Neilan , Steven Horan , Gerald Rabitte , Gerry McCaffrey
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B2017/2212 , A61B2017/2215 , A61F2002/016 , A61F2002/018 , A61F2230/0067 , A61F2230/0093
摘要： A support 103 for an embolic protection device comprises round wires 116 which may form one or more support hoops for a filter body. The circumferential hoop formed by the wires 116 ensures that in the expanded position, the filter body 102 will be supported by the support frame 103 in circumferential apposition with the interior wall of the vasculature. The wires 116 may have a strain distributing linkage element in the form of a loop 120. The loop 120 acts as a diameter or circumference adjuster allowing an embolic protection device to adapt to different Bessel contours and sizes whilst maintaining apposition with the vessel wall. The strain relieving geometry of the loops enhances the compliance of the bend points without creating a weakened hinge point, thus ensuring that there is no discontinuity in the circumferential seal against the vessel wall.
摘要翻译：用于栓塞保护装置的支撑件103包括圆形线116，其可以形成用于过滤器主体的一个或多个支撑环。由导线116形成的圆周箍确保在扩展位置中，过滤器主体102将由支撑框架103与脉管系统的内壁周向配合地支撑。电线116可以具有环路120形式的应变分布联动元件。环120用作直径或周长调节器，允许栓塞保护装置适应不同的贝塞尔轮廓和尺寸，同时保持与血管壁的配合。环的应变消除几何增加弯曲点的顺应性，而不产生削弱的铰链点，从而确保在围绕血管壁的周向密封中不存在中断。

97. 发明申请

US20060293696A1 Retrieval catheter 审中-公开
标题翻译：检索导管
公开(公告)号：US20060293696A1
公开(公告)日：2006-12-28
申请号：US11407355
申请日：2006-04-18
申请人： Gary Fahey , Ronald Kelly , Patrick Griffin , Eamon Brady , David Vale , John Neilan
发明人： Gary Fahey , Ronald Kelly , Patrick Griffin , Eamon Brady , David Vale , John Neilan
IPC分类号： A61B17/22
CPC分类号： A61L29/18 , A61B17/22031 , A61B17/221 , A61B90/39 , A61B2017/22035 , A61B2017/2215 , A61F2002/011
摘要： A retrieval catheter (200) comprises a catheter shaft (2) and a retrieval catheter tip at the distal end of the shaft (2). The tip comprises an expandable tip body (201) and two reinforcement columns (6, 7) extending along the tip body (201) embedded within the tip body (201). The tip body (201) comprises a stiff, distal, radiopaque segment (203) and a soft, proximal segment (202). The distal segment (203) has a distal nose part (205) extending distally of the reinforcement columns (6, 7). Along the distal nose part (205), the wall thickness of the tip body (201) tapers distally from a smaller wall thickness to a larger wall thickness, and the internal diameter tapers distally from a larger diameter to a smaller diameter.
摘要翻译：回收导管（200）包括在轴（2）的远端处的导管轴（2）和取回导管尖端。所述尖端包括可扩展尖端体（201）和沿着嵌入在所述尖端体（201）内的所述尖端体（201）延伸的两个加强柱（6,7）。尖端体（201）包括刚性的，远端的不透射线段（203）和柔软的近侧段（202）。远端段（203）具有远端加强柱（6,7）延伸的远端部分（205）。沿着远端鼻部（205），顶端体（201）的壁厚从较小的壁厚向远端逐渐变细到更大的壁厚，并且内径从较大的直径向远端逐渐变细到较小的直径。

98. 发明授权

US07014647B2 Support frame for an embolic protection device 有权
标题翻译：用于栓塞保护装置的支撑框架
公开(公告)号：US07014647B2
公开(公告)日：2006-03-21
申请号：US10326920
申请日：2002-12-23
申请人： Eamon Brady , David Vale , Ronald Kellly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
发明人： Eamon Brady , David Vale , Ronald Kellly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61B2017/2212 , A61B2017/2215 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要： An embolic protection device has a support frame incorporating tethering features for connecting the support frame distally and/or proximally and/or intermediately to a carrier. Tethers may also be used additionally or alternatively for connecting various elements of a support frame. The tethers may be used to connect a support hoop 503 to a tubular member 504. The tethers provide added safety and stability to the frame without any increase in the length of the device when wrapped down for delivery.
摘要翻译：栓塞保护装置具有支撑框架，其包括用于将支撑框架向远侧和/或向近侧和/或中间连接到载体的束缚特征。系绳也可以额外地或替代地用于连接支撑框架的各种元件。系绳可用于将支撑环503连接到管状构件504。系绳为框架提供了额外的安全性和稳定性，而在包装时不会增加设备的长度以便传送。

99. 发明授权

US09301769B2 Clot retrieval device for removing clot from a blood vessel 有权
标题翻译：用于从血管中去除凝块的凝块取出装置
公开(公告)号：US09301769B2
公开(公告)日：2016-04-05
申请号：US13823060
申请日：2012-03-09
申请人： Eamon Brady , Michael Gilvarry , Mahmood K. Razavi , David Vale , Patrick Griffin , Brendan Casey , Jason McNamara
发明人： Eamon Brady , Michael Gilvarry , Mahmood K. Razavi , David Vale , Patrick Griffin , Brendan Casey , Jason McNamara
IPC分类号： A61B17/22 , A61B17/221 , A61F2/01 , A61B17/3207
CPC分类号： A61B17/221 , A61B17/22031 , A61B17/320725 , A61B2017/00292 , A61B2017/00526 , A61B2017/00867 , A61B2017/22034 , A61B2017/22094 , A61B2017/2212 , A61B2017/2215 , A61F2/013 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2230/0069 , A61F2230/008 , A61F2230/0091 , A61F2230/0093
摘要： A clot retrieval device (9501) for removing occlusive clot from a blood vessel comprises an inner elongate body (9503) and an outer elongate body (9504) at least partially overlying the inner elongate body (9503). The device also comprises an elongate member or shaft (9502) having a proximal end which extends exterior of a patient so that a user can retrieve the stent-basket device and captured clot by retracting the shaft (9502). The outer elongate body (9504) and the inner elongate body (9503) are connected to the distal end of the shaft (9502) and are expandable relative to the shaft (9502) from a collapsed delivery configuration to an expanded deployed configuration. The outer elongate body (9504) is expandable relative to the inner elongate body (9503) to a radial extent which is greater than the radial extent of the inner body (9503) in the deployed configuration.
摘要翻译：用于从血管去除闭塞凝块的凝块取出装置（9501）包括至少部分地覆盖内部细长体（9503）的内部细长体（9503）和外部细长体（9504）。所述装置还包括细长构件或轴（9502），所述细长构件或轴（9502）具有延伸到患者外部的近端，使得使用者可以通过缩回所述轴（9502）来收回所述支架筐装置和所述血块。外部细长主体（9504）和内部细长主体（9503）连接到轴（9502）的远端并且可相对于轴（9502）从折叠的输送配置可扩展到展开的展开配置。外部细长体9504可相对于内部细长体9503扩张到在展开构型中大于内部主体9503的径向范围的径向程度。

100. 发明申请

US20140277079A1 CLOT RETRIEVAL DEVICES 有权
标题翻译：衣服检索设备
公开(公告)号：US20140277079A1
公开(公告)日：2014-09-18
申请号：US13829684
申请日：2013-03-14
申请人： David Vale , Eamon Brady , Michael Gilvarry , Mahmood Ravazi
发明人： David Vale , Eamon Brady , Michael Gilvarry , Mahmood Ravazi
IPC分类号： A61B17/221
CPC分类号： A61B17/221 , A61B2017/22034 , A61B2017/22061 , A61B2017/22094 , A61B2017/2215
摘要： A self-expandable mechanical clot retrieval device is designed variously to dislodge, engage and retract blood clot from extremely small and tortuous vasculature. The retrieval device comprises an elongate member and a plurality of ring elements. The ring elements may comprise a plurality of struts and crowns interconnected by a tether formed at a distal end of the elongate member or may be a separate component attached thereto. At least one tether may connect each ring element to the elongate member to restrain the ring element in a collapsed configuration during delivery of the retrieval device through an intravascular microcatheter. The tether connecting the ring element to the elongate member disengages when the retrieval device is positioned at the occluded site and the microcatheter is retracted to allow the self-expandable ring elements to reach an expanded configuration.
摘要翻译：可自动扩张的机械凝块取出装置被设计成不同程度地从非常小且弯曲的脉管系统中移出，接合和收回血块。检索装置包括细长构件和多个环形元件。环形元件可以包括通过形成在细长构件的远端处的系绳互连的多个支柱和冠部，或者可以是附接到其上的单独部件。至少一个系绳可以将每个环形元件连接到细长构件，以在通过血管内微导管递送检索装置期间将环形元件限制在折叠构型。当拾取装置定位在闭塞位置并且微导管缩回以允许自扩张环元件达到扩张构型时，将环形元件连接到细长构件的系绳脱离。

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