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    • 94. 发明申请
    • Fixing device and image forming device provided with the same
    • 固定装置及其设置的图像形成装置
    • US20050031387A1
    • 2005-02-10
    • US10938795
    • 2004-09-13
    • Katsuyuki YokoiMasashi Suzuki
    • Katsuyuki YokoiMasashi Suzuki
    • G01J5/12F16C13/00G01J5/14G03G15/20
    • G03G15/2057
    • A fixing device has a fixing unit and a temperature detection unit. The fixing unit includes a heat roller provided with a roller section and a heater section, and a pressure roller in pressure contact with the heat roller. These rollers are disposed in a protective cover. The roller section includes a base layer of aluminum formed into a hollow cylindrical shape, a black radiation layer, and a toner parting layer. The heater section is disposed in a hollow space of the base layer. In this heat roller, when heat is emitted from the heater section, and the heat is transmitted to the radiation layer via the base layer, greater amount of infrared radiation is emitted from the radiation layer than in the case of a heat roller that is not equipped with the radiation layer. The temperature detecting unit includes an infrared radiation sensor. Thus, even if a noise component is absorbed to some extent by locating the sensor at a distance from the heat roller on an outside of the protective cover, the temperature of the heat roller is detected accurately.
    • 定影装置具有定影单元和温度检测单元。 定影单元包括设置有辊部和加热部的加热辊以及与加热辊压接的加压辊。 这些辊子设置在保护罩中。 辊部分包括形成中空圆柱形状的铝基底层,黑色辐射层和调色剂分离层。 加热器部分设置在基层的中空空间中。 在该加热辊中,当从加热器部分发出热量,并且热量经由基底层传递到辐射层时,从辐射层发射的红外线辐射量比不是 配有辐射层。 温度检测单元包括红外线辐射传感器。 因此,即使通过将传感器定位在距保护罩外侧的加热辊一定距离处,某种程度的噪声成分被吸收,也能准确地检测出加热辊的温度。
    • 97. 发明授权
    • Depsipeptides and drugs containing the same as the active ingredient
    • 含有与活性成分相同的多肽和药物
    • US06255286B1
    • 2001-07-03
    • US09214002
    • 1998-12-24
    • Makoto YanaiMasashi SuzukiNorio OshidaKoji KawamuraShigeru HiramotoOrie YasudaNobuhiro KinoshitaAkiko ShingaiMasako Takasu
    • Makoto YanaiMasashi SuzukiNorio OshidaKoji KawamuraShigeru HiramotoOrie YasudaNobuhiro KinoshitaAkiko ShingaiMasako Takasu
    • A61K3800
    • C07K5/1021A61K38/00C07K5/06043C07K5/06052C07K5/06104C07K5/101C07K7/06C07K11/00
    • Depsipeptides represented by the formula (1): (wherein: R1 is a straight or branched alkyl group of 5-20 carbon atoms or a straight or branched alkoxymethyl group of 5-15 carbon atoms; R2 is —A—B, —A—B—W, —A—B—W—D or —A—B—W—D—E, R3 is a hydroxyl group, a lower alkoxy group, a benzyloxy group, —Z, —Z—G or —Z—G—J, the above A, B, D, E, G and J independently each other are a residue of an amino acid selected from alanine, valine, leucine, isoleucine, serine, threonine, lysine, hydroxylysine, arginine, cysteine, methionine, phenylalanine, tyrosine, aspartic acid, asparagine, glutamic acid, glutamine and the like or an N—(C1-C4) alkyl derivative of these amino acid residues; the above W and Z independently each other are a residue of an amino acid selected from aspartic acid, asparagine, glutamic acid, glutamine, alanine, serine or lysine) or pharmacologically acceptable salts thereof. The depsipeptides have an activity of promoting the production of apolipoprotein E and are useful as a therapeutic agent for neurologic damages, especially for dementia, and further as a therapeutic agent for hyperlipemia.
    • 由式(1)表示的缩肽:其中:R1是5-20个碳原子的直链或支链烷基或5-15个碳原子的直链或支链烷氧基甲基; R2是-AB,-ABW,-ABWD 或-ABWDE,R3是羟基,低级烷氧基,苄氧基,-Z,-ZG或-ZGJ,上述A,B,D,E,G和J彼此独立地是氨基的残基 选自丙氨酸,缬氨酸,亮氨酸,异亮氨酸,丝氨酸,苏氨酸,赖氨酸,羟赖氨酸,精氨酸,半胱氨酸,甲硫氨酸,苯丙氨酸,酪氨酸,天冬氨酸,天冬酰胺,谷氨酸,谷氨酰胺等的N-酸或N-(C1-C4) 这些氨基酸残基的烷基衍生物;上述W和Z彼此独立地是选自天冬氨酸,天冬酰胺,谷氨酸,谷氨酰胺,丙氨酸,丝氨酸或赖氨酸的氨基酸的残基)或其药理学上可接受的盐。脱脂肽具有 促进载脂蛋白E的产生的活性并且可用作治疗 用于神经损伤的特异剂,特别是对于痴呆,并且作为高脂血症的治疗剂。