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91. 发明授权

US09173861B2 Thiadiazole-substituted arylamides as P2X3 and P2X2/3 antagonists 有权
标题翻译：噻二唑取代的芳酰胺如P2X3和P2X2 / 3拮抗剂
公开(公告)号：US09173861B2
公开(公告)日：2015-11-03
申请号：US13359330
申请日：2012-01-26
申请人： Li Chen , Lichun Feng , Minmin Yang , Michael Patrick Dillon , Yingjie Lai
发明人： Li Chen , Lichun Feng , Minmin Yang , Michael Patrick Dillon , Yingjie Lai
IPC分类号： A61K31/166 , A61K31/497 , A61K31/4427 , A61K31/444 , A61K31/4436 , A61K31/4439 , C07D417/14 , C07C233/69 , A61K31/433
CPC分类号： C07D417/14 , A61K31/166 , A61K31/433 , A61K31/4427 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/497 , C07D285/06 , C07D417/12
摘要： Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted thiadiazolyl, and R2, R3, R4, R5, R6, R7 and R8 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.
摘要翻译：式I化合物或其药学上可接受的盐，其中R 1为任选取代的噻二唑基，R 2，R 3，R 4，R 5，R 6，R 7和R 8如本文所定义。还公开了使用该化合物治疗与P2X3和/或P2X2 / 3受体拮抗剂相关疾病的方法和制备该化合物的方法。

92. 发明授权

US08866691B2 Multimode antenna structure 有权
标题翻译：多模天线结构
公开(公告)号：US08866691B2
公开(公告)日：2014-10-21
申请号：US12727531
申请日：2010-03-19
申请人： Mark T. Montgomery , Mark W. Kishler , Li Chen
发明人： Mark T. Montgomery , Mark W. Kishler , Li Chen
IPC分类号： H01Q21/00
CPC分类号： H01Q21/28 , H01Q1/24 , H01Q1/243 , H01Q1/36 , H01Q1/38 , H01Q1/48 , H01Q1/521 , H01Q5/0034 , H01Q5/321 , H01Q5/35 , H01Q5/371 , H01Q9/285 , H01Q9/30 , H01Q21/205 , H01Q21/293
摘要： A multimode antenna structure is provided for transmitting and receiving electromagnetic signals in a communications device. The communications device includes circuitry for processing signals communicated to and from the antenna structure. The antenna structure includes a plurality of antenna ports for coupling to the circuitry; a plurality of antenna elements, each operatively coupled to a different one of the antenna ports; and a plurality of connecting elements. The connecting elements each electrically connect neighboring antenna elements such that the antenna elements and the connecting elements are arranged about the periphery of the antenna structure and form a single radiating structure. Electrical currents on one antenna element flow to connected neighboring antenna elements and generally bypass the antenna ports coupled to the neighboring antenna elements such that an antenna mode excited by one antenna port is generally electrically isolated from a mode excited by another antenna port at a given desired signal frequency range, and the antenna structure generates diverse antenna patterns.
摘要翻译：提供多模天线结构用于在通信设备中发送和接收电磁信号。通信设备包括用于处理与天线结构通信的信号的电路。天线结构包括用于耦合到电路的多个天线端口; 多个天线元件，每个天线元件可操作地耦合到不同的一个天线端口; 和多个连接元件。连接元件各自电连接相邻的天线元件，使得天线元件和连接元件围绕天线结构的周边布置并且形成单个辐射结构。一个天线元件上的电流流向连接的相邻天线元件，并且通常旁路耦合到相邻天线元件的天线端口，使得由一个天线端口激励的天线模式通常与给定期望的另一天线端口激发的模式电隔离信号频率范围，天线结构产生不同的天线方向图。

93. 发明授权

US08779328B2 Methods for laser cutting tubing to make medical devices 有权
标题翻译：激光切割管道制作医疗器械的方法
公开(公告)号：US08779328B2
公开(公告)日：2014-07-15
申请号：US12757842
申请日：2010-04-09
申请人： Boris Anukhin , Larry Baughman , Pamela A. Kramer-Brown , Neil Burkhart , Li Chen , Duane M. DeMorre , Keif Fitzgerald , Gregory W. Johnson , Z. C. Lin , David Mackiewicz , Karim S. Osman , Randolf von Oepen , William E. Webler, Jr. , Travis R. Yribarren
发明人： Boris Anukhin , Larry Baughman , Pamela A. Kramer-Brown , Neil Burkhart , Li Chen , Duane M. DeMorre , Keif Fitzgerald , Gregory W. Johnson , Z. C. Lin , David Mackiewicz , Karim S. Osman , Randolf von Oepen , William E. Webler, Jr. , Travis R. Yribarren
IPC分类号： B23K26/38 , B23K26/40 , A61F2/06 , A61F2/07
CPC分类号： B23K26/4005 , A61F2/07 , A61F2/91 , B23K26/16 , B23K26/38 , B23K26/40 , B23K26/402 , B23K2101/04 , B23K2101/06 , B23K2103/50
摘要： Methods for making devices include providing a tubular member to be formed into a device, placing a removable sacrificial block material in the lumen of the tubular member and laser cutting the tubular member. A tubular member made from nickel-titanium alloy can be tightly adhered to a sacrificial sleeve utilizing the phase changes associated with nickel-titanium. A mandrel which includes an enlarged diameter section causes the workpiece to expand slightly within its elastic deformation range to dislodge islands from the workpiece. Such a mandrel could be formed from a tubular member which has a central lumen that can be used to deliver a pressurized medium to “blast” islands from the workpiece.
摘要翻译：制造装置的方法包括提供要形成装置的管状构件，将可移除的牺牲块材料放置在管状构件的内腔中并激光切割管状构件。利用与镍 - 钛相关联的相变，由镍 - 钛合金制成的管状部件可以紧密地粘附到牺牲套管上。包括扩大直径部分的心轴使得工件在其弹性变形范围内稍微膨胀以从工件移除岛。这种心轴可以由管状构件形成，该管状构件具有可用于将加压介质输送到工件的“鼓风”岛的中心腔。

94. 发明申请

US20140044074A1 RANDOM ACCESS METHOD AND APPARATUS BASED ON MULTIPLE UPLINK TIMING ADVANCES 有权
标题翻译：基于多个上行时序的随机访问方法和设备
公开(公告)号：US20140044074A1
公开(公告)日：2014-02-13
申请号：US14008482
申请日：2012-02-17
申请人： Li Chen , Fangli Xu , Jiamin Liu
发明人： Li Chen , Fangli Xu , Jiamin Liu
IPC分类号： H04W74/08
CPC分类号： H04W74/0833 , H04W56/0045
摘要： Disclosed are a random access method and apparatus based on multiple uplink timing advances. The method includes: when acquiring that a user equipment has multiple uplink timing advances, initiating, by a network side, for the user equipment a random access on a designated carrier of a secondary cell. According to the examples, random access in the SCell can be realized in scenarios that multi-TA is maintained.
摘要翻译：公开了一种基于多个上行链路定时进展的随机接入方法和装置。该方法包括：当获取用户设备具有多个上行链路定时提前时，由网络侧为所述用户设备发起在二次小区的指定载波上的随机接入。根据这些示例，可以在保持多TA的情况下实现SCell中的随机访问。

95. 发明申请

US20140037080A1 THRESHOLD ACTIVATED TELECONFERENCING 有权
标题翻译：阈值激活电话
公开(公告)号：US20140037080A1
公开(公告)日：2014-02-06
申请号：US13566066
申请日：2012-08-03
申请人： Al Chakra , Li Chen , Edward C. Flickinger , Lin Sun
发明人： Al Chakra , Li Chen , Edward C. Flickinger , Lin Sun
IPC分类号： H04M3/42
CPC分类号： H04M3/56 , H04M2203/5054
摘要： Embodiments of the present invention provide a method, system and computer program product for threshold activation of an audio teleconference. In an embodiment of the invention, a method for threshold activation of an audio teleconference is provided. The method includes receiving calls into a conference bridge for an audio conference and determining whether or not a threshold number of calls from corresponding callers have been received for the audio conference. The method also includes initiating the audio conference responsive to a threshold number of callers having called into the audio conference, but prohibiting initiation of the audio conference until the threshold number of callers have called into the audio conference.
摘要翻译：本发明的实施例提供了一种用于阈值激活音频电话会议的方法，系统和计算机程序产品。在本发明的一个实施例中，提供了用于阈值激活音频电话会议的方法。所述方法包括：将呼叫接收到用于音频会议的会议桥中，并确定是否已经为所述音频会议接收到来自相应呼叫者的阈值呼叫数。该方法还包括响应于已经被呼入音频会议的呼叫者的阈值数量启动音频会议，但是禁止启动音频会议，直到呼叫者的阈值数目已经被调入音频会议。

96. 发明授权

US08614303B2 Diagnostic methods for ubiquinated protein profiling 有权
标题翻译：泛素化蛋白质分析的诊断方法
公开(公告)号：US08614303B2
公开(公告)日：2013-12-24
申请号：US10498068
申请日：2002-12-11
申请人： Kiran Madura , Li Chen
发明人： Kiran Madura , Li Chen
IPC分类号： C07K1/22 , B01D15/38 , G01N33/566 , G01N30/02
CPC分类号： G01N33/6842 , G01N27/447 , G01N33/6803
摘要： Methods for establishing a protein expression profile of a biological sample, by contacting a biological sample with a ubiquitin-binding protein such that ubiquitinated and specific non-ubiquitinated protein (the IPS) bind to the ubiquitin-binding protein; isolating the IPS proteins; and analyzing the isolated IPS proteins, wherein an expression profile is generated.
摘要翻译：通过使生物样品与泛素结合蛋白质接触，使泛素化和特异性非泛素化蛋白质（IPS）与泛素结合蛋白结合，建立生物样品的蛋白质表达谱的方法; 分离IPS蛋白; 并分析分离的IPS蛋白质，其中产生表达谱。

97. 发明申请

US20130301394A1 CMUT ASSEMBLY WITH ACOUSTIC WINDOW 有权
标题翻译： CMUT组装与声音窗口
公开(公告)号：US20130301394A1
公开(公告)日：2013-11-14
申请号：US13467638
申请日：2012-05-09
申请人： Li Chen , Yongli Huang
发明人： Li Chen , Yongli Huang
IPC分类号： H04R17/00
CPC分类号： B06B1/0292 , A61B8/4272 , A61B8/4444 , B06B3/00 , G10K11/18 , G10K11/32 , H03H3/0072
摘要： In some implementations, a capacitive micromachined ultrasonic transducer (CMUT) apparatus includes one or more CMUTs or CMUT arrays, an acoustic window, a coupling medium, and a packaging substrate. The acoustic window may have various configurations, such as for reducing acoustic reflectance or increasing mechanical properties. In some examples, at least one of the CMUTs, the acoustic window or the coupling medium may include a focusing capability for focusing acoustic energy to or from the CMUT.
摘要翻译：在一些实施方式中，电容微加工超声换能器（CMUT）装置包括一个或多个CMUT或CMUT阵列，声窗，耦合介质和封装衬底。声窗可以具有各种构造，例如用于降低声反射率或增加机械性能。在一些示例中，CMUT，声窗或耦合介质中的至少一个可以包括用于将声能聚焦到或来自CMUT的聚焦能力。

98. 发明授权

US08577973B2 Accelerated micro blogging using correlated history and targeted item actions 失效
标题翻译：加速使用相关历史和目标项目动作的微博
公开(公告)号：US08577973B2
公开(公告)日：2013-11-05
申请号：US12826781
申请日：2010-06-30
申请人： Li Chen , John R. Hind , Yongcheng Li , Lun Xiao
发明人： Li Chen , John R. Hind , Yongcheng Li , Lun Xiao
IPC分类号： G06F15/16 , G06F17/00 , G06F17/20 , G06F17/21 , G06F17/22 , G06F17/24 , G06F17/25 , G06F17/26 , G06F17/27 , G06F17/28 , G06F3/00
CPC分类号： G06Q50/01 , H04L51/34
摘要： A computer implemented method correlates a digital resource with an electronic message. A processor detects a focus on a targeted item that identifies a digital resource. The targeted item is in a user history that presents a history of a user's access to multiple digital resources. The processor then auto-populates a draft of an electronic message with the targeted item that was focused in the user history.
摘要翻译：计算机实现的方法将数字资源与电子消息相关联。处理器检测到识别数字资源的目标项目的焦点。目标项目在用户历史中，呈现用户访问多个数字资源的历史记录。然后，处理器将自动填充电子消息的草稿，其中包含用户历史记录中所关注的目标项目。

99. 发明授权

US08543116B2 Method and base station for energy saving compensation 有权
标题翻译：方法和基站节能补偿
公开(公告)号：US08543116B2
公开(公告)日：2013-09-24
申请号：US13700717
申请日：2011-08-12
申请人： Dajun Zhang , Li Chen
发明人： Dajun Zhang , Li Chen
IPC分类号： H04W36/00
CPC分类号： H04W52/0206 , H04W24/02 , H04W28/06 , H04W52/0219 , H04W52/0258 , H04W52/367 , H04W72/0406 , H04W88/08 , Y02D70/00 , Y02D70/1222 , Y02D70/1224 , Y02D70/1226 , Y02D70/1242 , Y02D70/1262
摘要： The present invention relates to the technical field of wireless communications, is used for optimizing an energy saving mechanism, and provides a method for energy saving compensation, which method comprises: expanding, by a base station, a signal coverage area to form a new cell, when the energy saving activation requirements are met, so as to allow an energy-saving cell managed by the base station to switch users to the new cell and to activate the energy saving state; and when energy saving deactivation requirements are met, and if the energy-saving cell managed by the base station deactivates the energy saving state, then switching, by the base station, the users to the energy-saving cell and reducing the signal coverage area. The present invention optimizes currently available energy saving mechanisms and provides a solution capable of compensating the service loss of energy-saving cells.
摘要翻译：本发明涉及无线通信技术领域，用于优化节能机制，并提供一种节能补偿方法，该方法包括：由基站扩展信号覆盖区域，形成新的小区当满足节能激活要求时，使得由基站管理的节能小区将用户切换到新小区并激活节能状态; 并且当满足节能停用要求时，如果由基站管理的节能小区停止节能状态，则由基站将用户切换到节能小区并减少信号覆盖区域。本发明优化了当前可用的节能机制，并提供了一种能够补偿节能小区的业务损失的解决方案。

100. 发明申请

US20130210894A1 APPLICATION OF HIGHLY CONSERVED DOMAIN SEQUENCES FROM VIRAL GENOME AS TEMPLATE TO DESIGN THERAPEUTIC SLIRNAS 有权
标题翻译：将来自病毒基因组的高度保留的域序列应用于模板设计治疗性SLIRNAS
公开(公告)号：US20130210894A1
公开(公告)日：2013-08-15
申请号：US13388979
申请日：2011-09-19
申请人： York YuanYuan Zhu , Li Chen , Tiejun Li , Yixiang Lu , Yuncheng Sun , Jinkang Wang
发明人： York YuanYuan Zhu , Li Chen , Tiejun Li , Yixiang Lu , Yuncheng Sun , Jinkang Wang
IPC分类号： C12N15/115
CPC分类号： C12N15/115 , A61K31/713 , C12N2310/13 , C12N2310/16 , Y02A50/465
摘要： This invention relates to the application of the highly conserved sequences of viral genome, especially from a highly conserved domain of enteroviral genome as templates to design target small ligand RNAs (sliRNAs). The resulting sliRNAs are therapeutically active ingredients in the treatment of the related diseases caused by pathological angiogenesis.
摘要翻译：本发明涉及病毒基因组的高度保守序列的应用，特别是来自肠道病毒基因组的高度保守结构域作为模板来设计靶小配体RNA（sliRNA）。所得的sliRNA是治疗由病理性血管发生引起的相关疾病的治疗活性成分。

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