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91. 发明授权

US08257422B2 Over-the-wire detachment mechanism 有权
标题翻译：超线脱离机构
公开(公告)号：US08257422B2
公开(公告)日：2012-09-04
申请号：US12543941
申请日：2009-08-19
申请人： Darin G. Schaeffer , Jeffry S. Melsheimer
发明人： Darin G. Schaeffer , Jeffry S. Melsheimer
IPC分类号： A61F2/06
CPC分类号： A61M39/10 , A61M25/01 , A61M2039/0232 , A61M2039/0291
摘要： A detachment mechanism, and methods of use, for use in delivering a medical device preferably over a guidewire are provided. The detachment mechanism includes a first and second engagement member. The members are configured to receive the guidewire and have a first end attached to the control member and the device, respectively, a second end, and a notch formed in the body to form an interlocking tooth. The notch is sized to receive the interlocking tooth of the other member. The members are interlockable to couple the medical device to the control member and to allow the guidewire to pass therethrough. The notch can be angled to permit easier detachment between the members and for better torqueability and pushability/pullability between the control member and the medical device. The members can also include a bend region configured to enhance bendability along a portion of the members.
摘要翻译：提供了一种用于优选地通过导线递送医疗装置的分离机构和使用方法。分离机构包括第一和第二接合构件。所述构件构造成接收所述导丝，并且具有分别附接到所述控制构件和所述装置的第一端和形成在所述主体中以形成互锁齿的凹口的第一端。凹口的尺寸被设计成接收另一个构件的互锁齿。构件可互锁以将医疗装置连接到控制构件并允许导丝通过。凹口可以成角度以允许在构件之间更容易地分离，并且在控制构件和医疗装置之间具有更好的可逆性和可推动性/可拉伸性。构件还可以包括弯曲区域，该弯曲区域被构造成增强沿着构件的一部分的弯曲性。

92. 发明申请

US20120201095A1 SYSTEM AND METHOD FOR PACKAGING AND MIXING MULTI-PART MEDICANT 审中-公开
标题翻译：用于包装和混合多部分药物的系统和方法
公开(公告)号：US20120201095A1
公开(公告)日：2012-08-09
申请号：US13353671
申请日：2012-01-19
申请人： Jeffry S. Melsheimer
发明人： Jeffry S. Melsheimer
IPC分类号： B01F13/00 , B65D25/08
CPC分类号： B01F11/0065 , B01F2215/0029
摘要： Disclosed is a system for mixing and dispensing bone cement. The system includes a flexible bag containing isolated liquid and powder components that are reactive with each other to form bone cement and a mixing device that has first and second primary pressure surfaces and first and second secondary curved pressure surfaces. The system allows the bag to attach to the first and second secondary pressure surfaces. The system is operated such that the first primary pressure surface exerts force on the bag against the first secondary pressure surface and the second primary pressure surface exerts force on the bag against the second secondary pressure surface. Relative movement of the primary pressure surfaces with respect to the bag causes mixing of the components within the bag.
摘要翻译：公开了一种用于混合和分配骨水泥的系统。该系统包括柔性袋，其包含彼此反应以形成骨粘固剂的分离的液体和粉末组分，以及具有第一和第二主要压力表面以及第一和第二次级弯曲压力表面的混合装置。该系统允许袋附接到第一和第二二次压力表面。操作该系统，使得第一主要压力表面对袋子施加相对于第一次级压力表面的力并且第二主要压力表面对袋子施加相对于第二次级压力表面的力。初级压力表面相对于袋的相对运动导致袋内部件的混合。

93. 发明申请

US20120172913A1 DELIVERY OF AN EMBOLIZATION COIL WITH AN ATTACHER 审中-公开
标题翻译：交付带有附件的嵌入式线圈
公开(公告)号：US20120172913A1
公开(公告)日：2012-07-05
申请号：US13338739
申请日：2011-12-28
申请人： Michael R. Kurrus , William F. Moore , Jeffry S. Melsheimer , Kathryn R. Evert
发明人： Michael R. Kurrus , William F. Moore , Jeffry S. Melsheimer , Kathryn R. Evert
IPC分类号： A61F2/01
CPC分类号： A61B17/12022 , A61B2017/00477 , A61B2017/00871 , A61B2017/12054 , A61B2017/12095
摘要： An occluding device apparatus includes an embolization coil with a distal end and a proximal end with an opening and an attacher that is threaded through the opening at the proximal end of the embolization coil. The apparatus further comprises a delivery kit for delivery of the embolization coil in a body cavity. The kit comprises a guide catheter for percutaneous introduction of the embolization coil and an inner catheter slidably disposed within the guide catheter during insertion. The inner catheter comprises a proximal end and a distal end. The inner catheter further includes a hub disposed adjacent the proximal end. The kit further comprises a guide wire slidably disposed within the inner catheter. The guide wire is configured to provide a path during insertion thereof within a body cavity. The kit further comprises a pushwire to advance the embolization coil through the inner catheter.
摘要翻译：闭塞装置装置包括具有远端的栓塞线圈和具有开口的近端和穿过栓塞线圈的近端处的开口的附件。该装置还包括用于在体腔中输送栓塞线圈的递送套件。该套件包括用于经皮引入栓塞线圈的引导导管和在插入期间可滑动地设置在引导导管内的内导管。内导管包括近端和远端。内导管还包括邻近近端设置的毂。套件还包括可滑动地设置在内导管内的导丝。引导线被配置成在将其插入体腔内时提供路径。套件还包括推动栓塞线圈穿过内导管的推挽线。

94. 发明授权

US08137291B2 Wire guide having distal coupling tip 有权
标题翻译：导线器具有远端连接头
公开(公告)号：US08137291B2
公开(公告)日：2012-03-20
申请号：US11549466
申请日：2006-10-13
申请人： Jeffry S. Melsheimer
发明人： Jeffry S. Melsheimer
IPC分类号： A61M25/00
CPC分类号： A61M25/09 , A61M25/0905 , A61M2025/09083 , A61M2025/09175 , A61M2025/09183
摘要： A coupling wire guide generally includes a main body defined by a first wire wound around a safety wire. A first loop is defined by an enlarged revolution of the first wire within a distal portion of the main body. The first loop is sized to receive a previously introduced wire guide for coupling the two wire guides.
摘要翻译：耦合导线器通常包括由缠绕在安全线上的第一线限定的主体。第一回路由主体的远侧部分内的第一线的扩大旋转限定。第一回路的尺寸被设计成接收先前引入的用于联接两个导线器的导线器。

95. 发明授权

US08133190B2 Weldable wire guide with distal coupling tip 有权
标题翻译：带远端连接头的焊接导线
公开(公告)号：US08133190B2
公开(公告)日：2012-03-13
申请号：US11763355
申请日：2007-06-14
申请人： Jeffry S. Melsheimer , Brenton S. Krieble
发明人： Jeffry S. Melsheimer , Brenton S. Krieble
IPC分类号： A61B5/00
CPC分类号： B23K1/0008 , A61L31/022 , B23K2101/38
摘要： A coupling wire guide structured to be slidably coupled to a previously introduced wire guide. The coupling wire guide includes a main body and a coupling tip, the coupling tip having first and second sections. The first section is connected to the main body, while the second section defines an axial passageway having a distal opening and a proximal opening. The axial passageway is sized to receive the previously introduced wire guide therein. Both a distal portion of the main body and the first section are constructed of nitinol, the distal portion and the first section being welded together using the native nitinol material of the distal portion and first section.
摘要翻译：耦合导线引导件，其被构造成可滑动地联接到先前引入的导线器。耦合导线器包括主体和联接尖端，联接尖端具有第一和第二部分。第一部分连接到主体，而第二部分限定具有远侧开口和近侧开口的轴向通道。轴向通道的尺寸适于接收先前引入的导线器。主体的远端部分和第一部分都由镍钛诺构成，远端部分和第一部分使用远端部分和第一部分的天然镍钛诺材料焊接在一起。

96. 发明授权

US07963987B2 Sequential implant delivery system 有权
标题翻译：顺序种植体输送系统
公开(公告)号：US07963987B2
公开(公告)日：2011-06-21
申请号：US11966369
申请日：2007-12-28
申请人： Jeffry S. Melsheimer , Mark A. Magnuson
发明人： Jeffry S. Melsheimer , Mark A. Magnuson
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/966 , A61F2002/826 , A61F2002/9665
摘要： A method and device includes advancing a first stent and a second stent into a stenosed region of a blood vessel to protect or shield the vessel from possible blockage. The delivery device may include placement rings, selectively engagable by positioning members disposed on the outer wall of in inner catheter. The positioning members and the placement rings may be utilized to accurately place multiple stents within an afflicted vessel, in a single invasive procedure.
摘要翻译：一种方法和装置包括将第一支架和第二支架推进到血管的狭窄区域中，以保护或屏蔽血管免受可能的阻塞。输送装置可以包括放置环，通过定位位于内导管的外壁上的构件来选择性地接合。定位构件和放置环可以用于以单一侵入性程序将多个支架精确地放置在受影响的血管内。

97. 发明申请

US20110046712A1 LOADING APPARATUS AND SYSTEM FOR EXPANDABLE INTRALUMINAL MEDICAL DEVICES 有权
标题翻译：用于可扩展的内镜医疗装置的装载装置和系统
公开(公告)号：US20110046712A1
公开(公告)日：2011-02-24
申请号：US12860422
申请日：2010-08-20
申请人： Jeffry S. Melsheimer , Jessica L. Burke , Sean D. Chambers , Arman Valaie
发明人： Jeffry S. Melsheimer , Jessica L. Burke , Sean D. Chambers , Arman Valaie
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2/2436 , A61F2/844 , A61F2/92 , A61F2002/9511 , A61F2002/9522 , Y10T29/53843
摘要： Medical device loading apparatuses, systems, methods and kits are described. A loading apparatus comprises a main body having a proximal end defining a proximal opening, a distal end defining a distal opening, and a passageway extending between the proximal and distal openings. The passageway defines a proximal chamber having a first inner diameter, a distal chamber having a second inner diameter, and a transition chamber disposed between the proximal and distal chambers. The transition chamber has an inner diameter that transitions from the larger second inner diameter to the smaller first inner diameter. The main body has a separable connection that divides the main body between proximal and distal portions when disrupted. An expandable intraluminal medical device can be loaded into a delivery catheter using the loading apparatus by placing the device into the passageway such that it is in a radially-expanded configuration; pulling the device along an axial path through the loading apparatus such that the device transitions from the radially-expanded configuration to a radially-compressed configuration; and pushing the radially-compressed device along the axial path into the delivery catheter.
摘要翻译：描述了医疗装置装载装置，系统，方法和试剂盒。装载装置包括主体，其具有限定近端开口的近端，限定远侧开口的远端以及在近端开口和远端开口之间延伸的通道。所述通道限定具有第一内径的近侧腔室，具有第二内径的远侧腔室，以及设置在近端腔室和远端腔室之间的过渡腔室。过渡室具有从较大的第二内径向较小的第一内径转变的内径。主体具有可分离的连接，当中断时将主体分成近端部分和远端部分之间。可扩张的管腔内医疗装置可以通过将装置放置在通道中以使其处于径向展开的构型中而使用装载装置装载到输送导管中; 沿着轴向路径拉动装置通过装载装置，使得装置从径向展开的构型转变成径向压缩的构型; 并将径向压缩的装置沿轴向路径推入输送导管。

98. 发明申请

US20100318068A1 WIRE GUIDE HAVING DISTAL COUPLING TIP FOR ATTACHMENT TO A PREVIOUSLY INTRODUCED WIRE GUIDE 审中-公开
标题翻译：具有与先前引入的导线连接的远程连接提示的导线
公开(公告)号：US20100318068A1
公开(公告)日：2010-12-16
申请号：US12858712
申请日：2010-08-18
申请人： Jeffry S. Melsheimer
发明人： Jeffry S. Melsheimer
IPC分类号： A61M25/09
CPC分类号： A61M25/0905
摘要： A coupling wire guide structured to be slidably coupled to a previously introduced wire guide. The coupling wire guide generally includes a main body having a distal end and a coupling tip connection to the distal end. The coupling tip includes a coupling portion defining a coupling passageway having a proximal port and a distal port. A slot is formed in the coupling tip and is in communication with the coupling passageway. The slot extends from the proximal port to the distal port, thereby permitting the coupling wire guide to be “clipped-on” to the mid-section of the previously introduced wire guide or any location having the most efficacy.
摘要翻译：耦合导线引导件，其被构造成可滑动地联接到先前引入的导线器。耦合线导向器通常包括主体，其具有远端和与远端的联接尖端连接。联接尖端包括限定具有近端口和远端口的联接通道的联接部分。在联接尖端中形成槽并与联接通道连通。狭槽从近端口延伸到远端口，从而允许联接导线引导件“夹紧”到先前引入的线导向件的中间部分或具有最高功效的任何位置。

99. 发明授权

US07762985B2 Balloon catheter for treating hardened lesions 有权
标题翻译：用于治疗硬化病变的气囊导管
公开(公告)号：US07762985B2
公开(公告)日：2010-07-27
申请号：US11925252
申请日：2007-10-26
申请人： Chris R. Kabrick , Jeffry S. Melsheimer
发明人： Chris R. Kabrick , Jeffry S. Melsheimer
IPC分类号： A61M31/00
CPC分类号： A61M25/104 , A61M25/0032 , A61M25/1002 , A61M25/1011 , A61M2025/0034 , A61M2025/0036 , A61M2025/1059 , A61M2025/1072
摘要： The present invention provides apparatus and methods for treating vascular conditions, and in particular, hardened or fibrous material in a stenosis. In a first embodiment, the apparatus comprises a catheter having proximal and distal regions and a plurality of balloons segments disposed on the distal region at intervals about a circumference of the catheter. A first set of opposing balloon segments are configured to be inflated at substantially the same time to apply a first pressure on the vascular condition, and then a second set of opposing balloon segments are configured to be inflated at substantially the same time to apply a second pressure on the vascular condition. The plurality of balloon segments may be formed by taking one length of balloon material and affixing the material to an outer surface of the catheter at a plurality of segment dividing locations to separate adjacent balloon segments, or alternatively, by providing multiple separate balloon materials.
摘要翻译：本发明提供了用于治疗血管病症的装置和方法，特别是狭窄中的硬化或纤维材料。在第一实施例中，该装置包括具有近端区域和远端区域的导管以及围绕导管圆周间隔设置在远侧区域上的多个气囊段。第一组相对的气囊段被配置为在基本相同的时间充气以在血管状态上施加第一压力，然后第二组相对的气囊段被构造成在基本相同的时间充气以施加第二对血管状况的压力。多个气囊段可以通过采取一段球囊材料并将材料固定在导管的外表面上，在多个分段位置处形成以分离相邻的球囊段，或者通过提供多个分开的球囊材料来形成。

100. 发明授权

US07731693B2 Coupling wire guide 有权
标题翻译：联轴器导轨
公开(公告)号：US07731693B2
公开(公告)日：2010-06-08
申请号：US11549473
申请日：2006-10-13
申请人： Jeffry S. Melsheimer
发明人： Jeffry S. Melsheimer
IPC分类号： A61M5/178 , A61M25/00 , A61B17/24 , A61B17/26
CPC分类号： A61M25/09 , A61B2017/003 , A61B2017/22042 , A61B2017/2212 , A61M25/0905 , A61M2025/09066
摘要： A coupling wire guide structured to be slidably coupled to a previously introduced wire guide. The coupling wire guide includes a main body having a distal section. The distal section includes an outer wire disposed over a safety wire. A loop wire is connected to the safety wire at two axially spaced points. At least a portion of the loop wire is positioned outside of the outer wire to define a loop area sized to receive the previously introduced wire guide.
摘要翻译：耦合导线引导件，其被构造成可滑动地联接到先前引入的导线器。耦合导线器包括具有远端部分的主体。远侧部分包括设置在安全线上的外部线。环形线在两个轴向间隔的点处连接到安全线。环线的至少一部分定位在外线的外侧，以限定尺寸适于接收先前引入的线引导件的环形区域。

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