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91. 发明授权

US07139614B2 Leads for pacing and/or sensing the heart from within the coronary veins 有权
公开(公告)号：US07139614B2
公开(公告)日：2006-11-21
申请号：US10431136
申请日：2003-05-07
申请人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren
发明人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead for monitoring or stimulating cardiac activity is provided. The lead is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead body has one or more electrodes associated therewith. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and urged into intimate contact a vessel wall. A method for implanting the lead into the coronary vasculature is also provided, the method comprising the steps of inserting a stylet into the lead, inserting the lead into the coronary sinus, advancing the lead from the coronary sinus toward the toward the left atrium and into a coronary vein, removing the stylet, and sensing and pacing the heart. Alternatively, the method comprises placing a guide catheter into the coronary sinus, threading a guide wire into the coronary veins, pushing the lead over the guide wire and into the coronary sinus or the coronary vein, and sensing and pacing the heart via the lead in its implanted site in the coronary sinus or the coronary vein.

92. 发明授权

US07016732B2 Cardiac rhythm management system with remotely activated capture verification for CHF and other patients 有权
公开(公告)号：US07016732B2
公开(公告)日：2006-03-21
申请号：US10338270
申请日：2003-01-07
申请人： Jay A. Warren , Jeffrey E. Stahmann
发明人： Jay A. Warren , Jeffrey E. Stahmann
IPC分类号： A61N1/365 , A61B5/04
CPC分类号： A61N1/371 , A61N1/3627
摘要： A cardiac rhythm management device capable of delivering multiple uni-chamber stimulation pulses to a patient's heart and suitable for verifying capture independently for each uni-chamber stimulation pulse. The uni-chamber capture verification mode of the cardiac rhythm management device may be activated via telemetry or by applying a magnetic field proximate the device. During the capture verification mode, bi-chamber pacing, for example, may precede or follow uni-chamber pacing to allow for pacing support. Also, the energy levels of the pacing stimulus over several beats may be varied, thereby verifying the programmed safety margins.

93. 发明授权

US06939345B2 Method for reducing restenosis in the presence of an intravascular stent 失效
标题翻译：在血管内支架存在下减少再狭窄的方法
公开(公告)号：US06939345B2
公开(公告)日：2005-09-06
申请号：US10397623
申请日：2003-03-26
申请人： Bruce H. KenKnight , Jay A. Warren , Stephen John Hahn
发明人： Bruce H. KenKnight , Jay A. Warren , Stephen John Hahn
IPC分类号： A61B18/14 , A61B18/04
CPC分类号： A61B18/1492 , A61B2018/00214 , A61B2018/0022 , A61B2018/00285 , A61B2018/00839
摘要： A first electrode is positioned within an artery proximate an implanted intravascular stent. A second electrode is positioned at a separate location relative the position of the first electrode. Electrical energy is then delivered between the first and the second electrodes to produce an electrical field adjacent the implanted intravascular stent. When a intravascular stent is implanted in a coronary artery, the delivery of the electrical energy is coordinated to cardiac cycles detected in sensed cardiac signals, where the delivery of the electrical energy between the first electrode and the second electrode occurs during a predetermined portion of the cardiac cycle.
摘要翻译：第一电极位于植入的血管内支架附近的动脉内。第二电极相对于第一电极的位置定位在单独的位置。然后在第一和第二电极之间传递电能，以产生邻近植入的血管内支架的电场。当将血管内支架植入冠状动脉中时，电能的传递与在感测到的心脏信号中检测到的心脏周期协调，其中第一电极和第二电极之间的电能的传递发生在第一电极和第二电极的预定部分期间心动周期。

94. 发明授权

US06574505B1 Atrial and ventricular implantable cardioverter-defibrillator and lead system 有权
标题翻译：心房和心室植入式心律转复除颤器及牵引系统
公开(公告)号：US06574505B1
公开(公告)日：2003-06-03
申请号：US09558288
申请日：2000-04-25
申请人： Jay A. Warren
发明人： Jay A. Warren
IPC分类号： A61N139
CPC分类号： A61N1/3622 , A61N1/3918 , A61N1/3925 , A61N1/3956
摘要： A cardiac rhythm management system, such as an implantable cardioverter-defibrillator (ICD), provides atrial anti-tachyarrhythmia therapy, such as a bipolar or unipolar electrical cardioversion countershock, or provides both atrial and ventricular anti-tachyarrhythmia therapy. The atrial and ventricular anti-tachyarrhythmia therapies have independent cardioversion-defibrillation energy levels and other parameters. The system provides an endocardial lead that is convenient to implant for providing anti-tachyarrhythmia therapy. The endocardial lead includes a first supraventricular electrode disposed in the atrium and superior vena cava, and optionally includes a first ventricular electrode and ICD housing electrode.
摘要翻译：诸如植入式心律转复除颤器（ICD）之类的心律管理系统提供心房反心律失常疗法，例如双相或单极电复律复发，或提供心房和心室心动过速心律失常治疗。心房和心室反心律失常疗法具有独立的心脏复律除颤能量等参数。该系统提供了一种便于植入物以提供抗快速性心律失常治疗的心内膜导联。心内膜包括设置在心房和上腔静脉中的第一室上电极，并且可选地包括第一心室电极和ICD外壳电极。

95. 发明授权

US06564100B2 Cardiac rhythm management system with remotely activated capture verification for CHF and other patients 有权
公开(公告)号：US06564100B2
公开(公告)日：2003-05-13
申请号：US09731124
申请日：2000-12-06
申请人： Jay A. Warren , Jeffrey E. Stahmann
发明人： Jay A. Warren , Jeffrey E. Stahmann
IPC分类号： A61N137
CPC分类号： A61N1/371 , A61N1/3627
摘要： A cardiac rhythm management device capable of delivering multiple uni-chamber stimulation pulses to a patient's heart and suitable for verifying capture independently for each uni-chamber stimulation pulse. The uni-chamber capture verification mode of the cardiac rhythm management device may be activated via telemetry or by applying a magnetic field proximate the device. During the capture verification mode, bi-chamber pacing, for example, may precede or follow uni-chamber pacing to allow for pacing support. Also, the energy levels of the pacing stimulus over several beats may be varied, thereby verifying the programmed safety margins.

96. 发明授权

US06317615B1 Method and system for reducing arterial restenosis in the presence of an intravascular stent 有权
标题翻译：在血管内支架存在下减少动脉再狭窄的方法和系统
公开(公告)号：US06317615B1
公开(公告)日：2001-11-13
申请号：US09294724
申请日：1999-04-19
申请人： Bruce H. KenKnight , Jay A. Warren , Stephen John Hahn
发明人： Bruce H. KenKnight , Jay A. Warren , Stephen John Hahn
IPC分类号： A61B504
CPC分类号： A61B18/1492 , A61B2018/00214 , A61B2018/0022 , A61B2018/00285 , A61B2018/00839
摘要： A first electrode is positioned within an artery proximate an implanted intravascular stent. A second electrode is positioned at a separate location relative the position of the first electrode. Electrical energy is then delivered between the first and the second electrodes to produce an electrical field adjacent the implanted intravascular stent. When a intravascular stent is implanted in a coronary artery, the delivery of the electrical energy is coordinated to cardiac cycles detected in sensed cardiac signals, where the delivery of the electrical energy between the first electrode and the second electrode occurs during a predetermined portion of the cardiac cycle.
摘要翻译：第一电极位于植入的血管内支架附近的动脉内。第二电极相对于第一电极的位置定位在单独的位置。然后在第一和第二电极之间传递电能，以产生邻近植入的血管内支架的电场。当将血管内支架植入冠状动脉中时，电能的传递与在感测到的心脏信号中检测到的心脏周期协调，其中第一电极和第二电极之间的电能的传递发生在第一电极和第二电极的预定部分期间心动周期。

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