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91. 发明专利

BRPI0813352A2 未知
公开(公告)号：BRPI0813352A2
公开(公告)日：2014-12-30
申请号：BRPI0813352
申请日：2008-06-05
申请人： ETHICON INC
发明人： GOSIEWSKA ANNA , SEYDA AGNIESZKA , BUENSUCESO CHARITO S , DHANARAJ SRIDEVI
IPC分类号： A61K35/34 , A61L27/38
摘要： Compositions for the treatment of incontinence are disclosed. More particularly, compositions of viable muscle tissue fragments and a carrier are disclosed. The compositions are useful in the treatment urinary and fecal incontinence.

92. 发明专利

DK2078073T3 NYREAFLEDTE CELLER OG FREMGANGSMÅDER TIL ANVENDELSE DERAF TIL VÆVSREPARATION OG -REGENERERING 未知
公开(公告)号：DK2078073T3
公开(公告)日：2013-10-28
申请号：DK07852651
申请日：2007-10-11
申请人： ETHICON INC
发明人： COLTER DAVID C , SEYDA AGNIESZKA , BUENSUCESO CHARITO S , GOSIEWSKA ANNA
IPC分类号： C12N5/074 , A61K35/12 , C12N5/071

93. 发明专利

AU2008343485B2 Decellularized omentum matrix and uses thereof 未知
公开(公告)号：AU2008343485B2
公开(公告)日：2013-08-22
申请号：AU2008343485
申请日：2008-12-04
申请人： ETHICON INC
发明人： BUENSUCESO CHARITO S , SEYDA AGNIESZKA , COLTER DAVID C , YANG CHUNLIN , GOSIEWSKA ANNA , JOHN THOPPIL MATHEW , SHISSIAS RAYMOND S
IPC分类号： A61L27/22 , A61L27/36 , A61L27/38 , A61L27/54
摘要： Methods for defatting omentum and processes for preparing an acellular omentum i.e., devitalized or decellularized omentum, comprising extracellular matrix for implantation into a mammalian system. Also constructs for medical applications comprising decellularized omentum.

94. 发明专利

DE602005024306D1 GEWEBEKONSTRUKTIONSVORRICHTUNGEN ZUR REPARATUR UND REGENERATION VON GEWEBE 未知
公开(公告)号：DE602005024306D1
公开(公告)日：2010-12-02
申请号：DE602005024306
申请日：2005-12-15
申请人： ETHICON INC
发明人： SEYDA AGNIESZKA , SCOPELIANOS ANGELO G , GEESIN JEFFREY C , GOSIEWSKA ANNA , SRIDEVI DHANARAJ , BUENSUCESO CHARITO S , COLTER DAVID C
IPC分类号： A61L27/38 , A61L27/18 , C12N5/071 , C12N5/077

95. 发明专利

AU2008343485A1 Decellularized omentum matrix and uses thereof 未知
公开(公告)号：AU2008343485A1
公开(公告)日：2009-07-09
申请号：AU2008343485
申请日：2008-12-04
申请人： ETHICON INC
发明人： GOSIEWSKA ANNA , YANG CHUNLIN , SHISSIAS RAYMOND S , SEYDA AGNIESZKA , BUENSUCESO CHARITO S , JOHN THOPPIL MATHEW , COLTER DAVID C
IPC分类号： A61L27/22 , A61L27/36 , A61L27/38 , A61L27/54
摘要： Methods for defatting omentum and processes for preparing an a cellular omentum i.e., devitalized or decellularized omentum, comprising extracellular matrix for implantation into a mammalian system. Also constructs for medical applications comprising decellularized omentum.

96. 发明专利

AU2008308531A1 Repair and regeneration of renal tissue using human umbilical cord tissue-derived cells 未知
公开(公告)号：AU2008308531A1
公开(公告)日：2009-04-09
申请号：AU2008308531
申请日：2008-10-03
申请人： ETHICON INC
发明人： COLTER DAVID , GOSIEWSKA ANNA
IPC分类号： A61K48/00 , A61K35/12 , A61K35/44 , C12N5/071 , C12N5/073
摘要： Methods for treating a patient having a disease or damage to at least one kidney are provided. The methods comprise administering cells obtained from human umbilical cord tissue, or administering pharmaceutical compositions comprising such cells or prepared from such cells. When administered, the cells promote and support the repair and regeneration of the diseased or damaged kidney tissue in the patient. Pharmaceutical compositions for use in the inventive methods, as well as kits for practicing the methods are also provided.

97. 发明专利

AU2006200194B2 Biocompatible scaffolds with tissue fragments 未知
公开(公告)号：AU2006200194B2
公开(公告)日：2009-02-12
申请号：AU2006200194
申请日：2006-01-17
申请人： ETHICON INC
发明人： GOSIEWSKA ANNA , BINETTE FRANCOIS , DHANARAJ SRIDEVI , HWANG JULIA

98. 发明专利

DE69734894T2 未知
公开(公告)号：DE69734894T2
公开(公告)日：2006-07-20
申请号：DE69734894
申请日：1997-10-24
申请人： ETHICON INC
发明人： GEESIN JEFFREY C , GOSIEWSKA ANNA
IPC分类号： A61K38/16 , G01N33/50 , A61K38/00 , A61K38/27 , A61K38/30 , A61K45/00 , A61P43/00 , C07K5/00 , C07K14/47 , C07K14/495 , C07K14/65 , G01N33/15 , G01N33/68

99. 发明专利

AU2005319401A1 Tissue engineering devices for the repair and regeneration of tissue 未知
公开(公告)号：AU2005319401A1
公开(公告)日：2006-06-29
申请号：AU2005319401
申请日：2005-12-15
申请人： ETHICON INC
发明人： SCOPELIANOS ANGELO G , DHANARAJ SRIDEVI , COLTER DAVID C , GEESIN JEFFREY C , SEYDA AGNIESZKA , BUENSUCESO CHARITO S , GOSIEWSKA ANNA
IPC分类号： A61L27/38 , A61L27/18 , C12N5/071 , C12N5/077
摘要： Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.

100. 发明专利

ES2253788T3 ENSAYO DE AGENTE ANTI-FIBROTICO. 未知
公开(公告)号：ES2253788T3
公开(公告)日：2006-06-01
申请号：ES97949342
申请日：1997-10-24
申请人： ETHICON INC
发明人： GEESIN JEFFREY C , GOSIEWSKA ANNA
IPC分类号： G01N33/50 , A61K38/00 , A61K38/27 , A61K38/30 , A61K45/00 , A61P43/00 , C07K14/47 , C07K14/495 , C07K14/65 , G01N33/15 , G01N33/68 , A61K38/16 , C07K5/00
摘要： SE HA DESARROLLADO UN NUEVO PROCEDIMIENTO PARA SELECCIONAR AGENTES ANTICICATRIZANTES Y ANTIFIBROTICOS. ESTE PROCEDIMIENTO OFRECE SIMPLICIDAD, ES REPRODUCIBLE Y PUEDE ADOPTARSE PARA SELECCIONAR UN GRAN NUMERO DE NUEVOS AGENTES POTENCIALMENTE ANTIFIBROTICOS. ESTE PROCEDIMIENTO TIENE CARACTERISTICAS EN COMUN CON EL SISTEMA DE CO-CULTIVO BAEC/BASMC, PERO ES MAS SENSIBLE Y NO REQUIERE LA SELECCION DE UN GRAN NUMERO DE LINEAS CLONALES PARA DESARROLLAR UN PROCEDIMIENTO EFECTIVO. EN ESTE SISTEMA, DE FORMA SIMILAR CON EL SISTEMA DE CO-CULTIVO, LA ACTIVACION DEL L-TGF- BE 1 SE PRODUCE MEDIANTE VARIOS MECANISMOS INDEPENDIENTES QUE COMPRENDEN LA UNION DEL COMPLEJO LATENTE CON LOS RECEPTORES M6P/IGF-II, LA TROMBOSPONDINA Y/O LA TRANSGLUTAMINASA DE TEJIDOS DE TIPO II. PERO, EN CONTRASTE CON EL SISTEMA DE CO-CULTIVO, ESTE SISTEMA DEPENDIENTE DE LOS MACROFAGOS NO PARECE INVOLUCRAR A LA PLASMINA. UTILIZANDO ESTE PROCEDIMIENTO, SE IDENTIFICARON NUEVOS AGENTES ANTIFIBROTICOS TALES COMO EL IGF-2 (UTILIZADO SEPARADAMENTE O EN COMBINACION CON EL IGFBP2 COMO VEHICULO DE ADMINISTRACION), LOS INHIBIDORES DE LA TRANSGLUTAMINASA DE TEJIDOS DE TIPO II Y AGENTES ANTIINFLAMATORIOS (TALES COMO LA HIDROCORTISONA). SE HA PROPUESTO UN NUEVO MECANISMO POTENCIAL DE ACCION PARA LA MANOSA 6-FOSFATO QUE SE BASA EN LA DESREGULACION DEL RECEPTOR DEL M6P/IGF-II Y TGF- BE 1 MARN.

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