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91. 发明专利

CA2414596A1 COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF LUNG CANCER 未知
公开(公告)号：CA2414596A1
公开(公告)日：2002-01-10
申请号：CA2414596
申请日：2001-06-28
申请人： CORIXA CORP
发明人： KALOS MICHAEL D , WANTANABE YOSHIHIRO , MCNEILL PATRICIA D , WANG TONGTONG , HENDERSON ROBERT A , CARTER DARRICK
IPC分类号： G01N33/53 , A61K35/14 , A61K38/00 , A61K39/00 , A61K39/395 , A61P35/00 , A61P43/00 , C07K14/47 , C07K16/32 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12N15/09 , C12N15/12 , C12Q1/68 , G01N33/566 , G01N33/574 , C07H21/00 , A61K48/00 , C07K16/18 , C12N15/63
摘要： Compositions and methods for the therapy and diagnosis of cancer, such as lung cancer, are disclosed. Compositions may comprise one or more lung tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a lung tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as lung cancer. Diagnostic methods based on detecting a lung tumor protein, or mRNA encoding such a protein, in a sample are also provided.

92. 发明专利

CA2407352A1 COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF ACNE VULGARIS 未知
公开(公告)号：CA2407352A1
公开(公告)日：2001-11-01
申请号：CA2407352
申请日：2001-04-20
申请人： CORIXA CORP
发明人： JEN SHYIAN , CARTER DARRICK , ZHANG YANNI , L MAISONNEUVE JEAN-FRANCOIS , SKEIKY YASIR A W , PERSING DAVID H , MITCHAM JENNIFER L , BHATIA AJAY , WANG SIQING STEVEN
IPC分类号： G01N33/53 , A61K39/00 , A61K39/07 , A61K39/39 , A61K48/00 , A61P17/02 , A61P29/00 , C07K14/195 , C07K16/12 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/31 , C12Q1/68 , C12R1/01 , G01N33/566 , G01N33/569 , A61K39/05 , A61K39/40 , C07K16/40 , C12N9/02 , C12N9/10 , C12N9/20 , C12N9/24 , C12N9/50 , C12N15/63 , G01N33/68
摘要： Compositions and methods for the therapy and diagnosis of acne vulgaris and other related conditions are disclosed. Compositions may comprise one or mor e Propionibacterium acnes proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antibody that binds a Propionibacterium acnes protein, antigen presenting cell that expresses a Propionibacterium acnes protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and/or treatment of acne.

93. 发明专利

AU3691101A Lipophilin complexes for use in cancer diagnosis and therapy 未知
公开(公告)号：AU3691101A
公开(公告)日：2001-08-20
申请号：AU3691101
申请日：2001-02-08
申请人： CORIXA CORP
发明人： CARTER DARRICK , VEDVICK THOMAS S , VALLIEVE-DOUGLASS JOHN , HOUGHTON RAYMOND L , DILLON DAVIN C
IPC分类号： A61K38/00 , A61K39/00 , C07K14/47 , G01N33/574

94. 发明专利

ES2326311T3 COMPOSICIONES Y METODOS PARA INMUNOTERAPIA ESPECIFICA CON WT1. 未知
公开(公告)号：ES2326311T3
公开(公告)日：2009-10-07
申请号：ES02797061
申请日：2002-10-30
申请人： CORIXA CORP
发明人： GAIGER ALEXANDER , MCNEILL PATRICIA D , JAYA NOMALIE , CARTER DARRICK
IPC分类号： C07K14/00 , A61K35/76 , C12N15/09 , A61K38/00 , A61K39/00 , A61K48/00 , A61P35/00 , A61P35/02 , C07K7/00 , C07K11/00 , C07K14/47 , C07K14/82 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/08 , C12N5/10
摘要： Una proteína de fusión que comprende una porción inmunógena de un antígeno de tumor de Wilms (WT1), en la que dicha porción inmunógena de WT1 consiste en la secuencia de aminoácidos seleccionada del grupo que consiste en las SEC ID Nº: 2, 144, 241, 414-451, 461, 478 y 502, y un compañero de fusión, caracterizada por que el compañero de fusión consiste en la secuencia de aminoácidos expuesta en la SEC ID Nº: 506.

95. 发明专利

DE60139150D1 未知
公开(公告)号：DE60139150D1
公开(公告)日：2009-08-13
申请号：DE60139150
申请日：2001-11-30
申请人： CORIXA CORP
发明人： WANG TONGTONG , WANG AIJUN , SKEIKY YASIR A W , LI SAMUEL X , KALOS MICHAEL D , HENDERSON ROBERT A , MCNEILL PATRICIA D , FANGER NEIL , RETTER MARC W , DURHAM MARGARITA , FANGER GARY R , VEDVICK THOMAS S , CARTER DARRICK , WATANABE YOSHIHIRO , PECKHAM DAVID W , CAI FENG , FOY TERESA M
IPC分类号： C12N15/12 , G01N33/574 , A61K31/7088 , A61K31/711 , A61K35/14 , A61K38/00 , A61K38/17 , A61K39/00 , A61K39/395 , A61K45/00 , A61P35/00 , A61P37/04 , C07K14/47 , C07K14/82 , C07K16/30 , C07K16/32 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/08 , C12N5/10 , C12N15/09 , C12Q1/68
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.

96. 发明专利

AT435284T 未知
公开(公告)号：AT435284T
公开(公告)日：2009-07-15
申请号：AT01990067
申请日：2001-11-30
申请人： CORIXA CORP
发明人： WANG TONGTONG , WANG AIJUN , SKEIKY YASIR , LI SAMUEL , KALOS MICHAEL , HENDERSON ROBERT , MCNEILL PATRICIA , FANGER NEIL , RETTER MARC , DURHAM MARGARITA , FANGER GARY , VEDVICK THOMAS , CARTER DARRICK , WATANABE YOSHIHIRO , PECKHAM DAVID , CAI FENG , FOY TERESA
IPC分类号： C12N15/12 , G01N33/574 , A61K31/7088 , A61K31/711 , A61K35/14 , A61K38/00 , A61K38/17 , A61K39/00 , A61K39/395 , A61K45/00 , A61P35/00 , A61P37/04 , C07K14/47 , C07K14/82 , C07K16/30 , C07K16/32 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/08 , C12N5/10 , C12N15/09 , C12Q1/68
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.

97. 发明专利

AU2007202776A1 Compositions and methods for the therapy and diagnosis of ovarian cancer 未知
公开(公告)号：AU2007202776A1
公开(公告)日：2007-07-12
申请号：AU2007202776
申请日：2007-06-14
申请人： CORIXA CORP
发明人： KING GORDON E , REED STEVEN G , ALGATE PAUL A , FANGER GARY RICHARD , ALBONE EARL , FLING STEVEN P , HILL PAUL , RETTER MARC W , CARTER DARRICK , MITCHAM JENNIFER L , VEDVICK THOMAS S
IPC分类号： C12N15/09 , A61K38/00 , A61K39/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P35/00 , C07K14/47 , C07K16/18 , C07K16/30 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/12
摘要： Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors. Polypeptides and polynucleotides as provided herein may further be used for the diagnosis and monitoring of ovarian cancer.

98. 发明专利

YU5002A JEDINJENJA I POSTUPCI ZA LEČENJE I DIJAGNOZU RAKA PLUĆA 未知
公开(公告)号：YU5002A
公开(公告)日：2005-06-10
申请号：YUP5002
申请日：2000-06-30
申请人： CORIXA CORP
发明人： WANG TONGTONG , BANGUR CHAITANYA S , LODES MICHAEL J , FANGER GARY R , VEDVICK THOMAS S , CARTER DARRICK , RETTER MARC , MANNION JANE
摘要： Otkrivene su kompozicije i postupci za terapiju i dijagnozu kancera, kao što je kancer pluća. Kompozicije mogu sadržati jedan ili više proteina tumor pluća, njegove imunogene delove, ili polinukieotide koji kodiraju takve delove. Alternativno, terapeutske kompozicije mogu sadržati antigen prikazujući ćeliju koja eksprimira proteina tumora pluća, ili T ćeliju koja je specifična za ćelije koje eksprimiraju takav protein. Takve kompozicije mogu biti korišćene za, na primer, prevenciju i tretman bolesti kao što je kancer pluća. Obezbedjeni su takodje i dijagnostički postupci zasnovani na detekciji proteina tumora pluća, ili iRNK koja kodira takav protein, unutar uzorka.[Compositions and methods for the therapy and diagnosis of cancer, such as lung cancer, are disclosed. Compositions may comprise one or more lung tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a lung tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as lung cancer. Diagnostic methods based on detecting a lung tumor protein, or mRNA encoding such a protein, in a sample are also provided.

99. 发明专利

NZ516381A Lung tumor proteins in the therapy and diagnosis of lung cancer 未知
公开(公告)号：NZ516381A
公开(公告)日：2004-03-26
申请号：NZ51638100
申请日：2000-06-30
申请人： CORIXA CORP
发明人： RETTER MARC W , MANNION JANE , WANG TONGTONG , BANGUR CHAITANYA S , LODES MICHAEL J , FANGER GARY R , VEDVICK THOMAS S , CARTER DARRICK
IPC分类号： G01N33/53 , A61K31/711 , A61K35/12 , A61K38/00 , A61K39/395 , A61K45/00 , A61P35/00 , A61P37/04 , C07K14/11 , C07K14/315 , C07K14/47 , C07K14/82 , C07K16/32 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/08 , C12Q1/68 , G01N33/566 , G01N33/574 , G01N33/58 , C07K14/705 , C07K16/18 , C12N15/62 , A61K38/17
摘要： An isolated polypeptide comprising at least an immunogenic portion of a lung tumor protein, a polynucleotide sequence encoding the polypeptide, antibodies raised against the lung tumor protein, pharmaceutical compositions and their uses for inhibiting the development of cancer in a patient

100. 发明专利

AU769143B2 Compositions and methods for the therapy and diagnosis of lung cancer 未知
公开(公告)号：AU769143B2
公开(公告)日：2004-01-15
申请号：AU5902700
申请日：2000-06-30
申请人： CORIXA CORP
发明人： WANG TONGTONG , BANGUR CHAITANYA S , LODES MICHAEL J , FANGER GARY R , VEDVICK THOMAS S , CARTER DARRICK , RETTER MARC W , MANNION JANE
IPC分类号： G01N33/53 , A61K31/711 , A61K35/12 , A61K38/00 , A61K39/395 , A61K45/00 , A61P35/00 , A61P37/04 , C07K14/11 , C07K14/315 , C07K14/47 , C07K14/82 , C07K16/32 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/08 , C12Q1/68 , G01N33/566 , G01N33/574 , G01N33/58 , A61K38/17 , C07K14/705 , C07K16/18 , C12N15/62
摘要： Compositions comprising isolated cancer-associated L552S polypeptides are disclosed. Such compositions can comprise, for example, portions of said cancer-associated L552S polypeptides and/or the corresponding polynucleotides encoding such portions. Illustrative uses of the compositions, for example in cancer diagnostic methods, are also provided.

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