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91. 发明专利

GB2408204A Mattress protection 未知
公开(公告)号：GB2408204A
公开(公告)日：2005-05-25
申请号：GB0327138
申请日：2003-11-21
申请人： UCL BIOMEDICA PLC
发明人： BAIN DUNCAN , PELL MARTIN FERGUSON , NICHOLSON GRAHAM
IPC分类号： A47C21/06 , A61F5/48 , A47C31/00
摘要： The present invention seeks to address the chronic and worsening problem of mattress management in hospitals by providing a mattress protector to shield a mattress or mattress core from body fluids, the protector not only comprising a shielding cover for the mattress or mattress core but also a detector in an inter-or under-layer of the cover to detect body fluid that has passed into or through the cover. The detector may be chemical, with the cover being a transparent cover and the under-layer being absorbent and having a dye that is activated by a body fluid to provide a visual indication of presence of the body fluid. In an alternative embodiment the detector may be an apparatus monitoring electrical conductivity. This suitably uses threads of electrically conductive yarn forming either the warp or weft of a thin flexible under layer of the protective cover and which are linked to a small processor which monitors the electrical conductivity between neighbouring conductive threads in the sensing layer.

92. 发明专利

CA2545115A1 IMPROVEMENTS RELATING TO SEMEN PRESERVATION 未知
公开(公告)号：CA2545115A1
公开(公告)日：2005-05-19
申请号：CA2545115
申请日：2004-11-08
申请人： UCL BIOMEDICA PLC
发明人： THURSTON LISA , MICHAEL ANTHONY
IPC分类号： C12Q1/32 , A61P15/08 , G01N33/50 , G01N33/68
摘要： The present invention provides a method for determining the suitability of a sample of mammalian semen for cooling and/or cryopreservation or storage, which comprises: (a) providing said sample of semen; (b) determining the lev el of a hydrophobic stimulator of 11.beta.-HSD activity in said sample; and (c) assessing, from the level of 11.beta.-HSD stimulator determined, the suitability of the semen sample for cooling and/or cryopreservation or storage. The present invention also provides a method of obtaining a hydrophobic product that improves the tolerance of mammalian semen to coolin g and/or cryopreservation or storage, a method of improving the survival rate of sperm intended for cooling and/or cryopreservation or storage and a method o f performing an assisted conception/reproductive procedure comprising contacti ng an oocyte with sperm obtained by a method according to the present invention .

93. 发明专利

CA2541396A1 CONJUGATE OF A PHOTOSENSITISER AND A BACTERIOPHAGE 未知
公开(公告)号：CA2541396A1
公开(公告)日：2005-04-21
申请号：CA2541396
申请日：2004-10-08
申请人： UCL BIOMEDICA PLC
发明人： WILSON MICHAEL , NAIR SEAN
IPC分类号： A61K41/00 , A61K47/48
摘要： A composition comprising a conjugate of a photosensitiser and a bacteriophage is provided. The conjugate may be used to kill bacteria, particularly MRSA, EMRSA, VRSA, hetero-VRSA or CA-MRSA in a targeted method of photodynamic therapy.

95. 发明专利

AU2004226692A1 A device for transfixing and joining tissue 未知
公开(公告)号：AU2004226692A1
公开(公告)日：2004-10-14
申请号：AU2004226692
申请日：2004-03-31
申请人： UCL BIOMEDICA PLC
发明人： MOSSE CHARLES ALEXANDER , SWAIN CHRISTOPHER PAUL , FRITSCHER-RAVENS ANNETTE DORA , MILLS TIMOTHY NOEL
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/11
摘要： A device is provided for use in joining together first and second tissue layers. The device comprises a catheter with an inflatable balloon mounted on the catheter adjacent one and thereof. An inflation channel is provided which is an fluid communication with the interior of the balloon and with a source of inflation fluid for introducing the inflation fluid into the interior of the balloon. The balloon is inflated and engages an outwardly facing surface of the first tissue layer and a tissue-engaging member, for example a cup or another balloon, engages an outwardly facing surface of the second tissue layer. The inwardly facing surfaces of the first and second tissue layers are thereby urged into engagement with on another.

96. 发明专利

GB0415080D0 Methods for preparing tissue equivalent implants and products thereof 未知
公开(公告)号：GB0415080D0
公开(公告)日：2004-08-04
申请号：GB0415080
申请日：2004-07-05
申请人： UCL BIOMEDICA PLC
IPC分类号： A61L27/24 , A61L27/38 , A61L27/52

98. 发明专利

CA2507761A1 CANCER ASSOCIATED PLEXINB1 MUTATIONS 未知
公开(公告)号：CA2507761A1
公开(公告)日：2004-06-17
申请号：CA2507761
申请日：2003-11-28
申请人： UCL BIOMEDICA PLC
发明人： MASTERS JOHN , WILLIAMSON MAGALI
IPC分类号： C12Q1/68 , C12Q1/6886 , G01N33/574 , G01N33/50
摘要： The present inventors have identified cancer associated mutations in plexinB 1, which is a transmembrane receptor that mediates semaphorin signalling. The frequency of plexinB1 mutations, in particular in prostate and breast cancer , indicates that plexinB1 may be useful in the screening and diagnosis of canc er and as a drug target in the development of anti-cancer therapeutics.

100. 发明专利

GB0401204D0 Polymer for use in conduits and medical devices 未知
公开(公告)号：GB0401204D0
公开(公告)日：2004-02-25
申请号：GB0401204
申请日：2004-01-20
申请人： UCL BIOMEDICA PLC
IPC分类号： C08G18/12 , C08G18/44 , C08G18/61 , C08G18/64 , C08G64/12 , C08G64/18 , C08G77/448 , C08G77/452

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