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91. 发明专利

BRPI0511710B8 comprimido mastigável, sugável e deglutível contendo cálcio 未知
公开(公告)号：BRPI0511710B8
公开(公告)日：2021-05-25
申请号：BRPI0511710
申请日：2005-05-24
申请人： NYCOMED PHARMA AS , TAKEDA AS , TAKEDA NYCOMED AS
发明人： DINA WULFF SORENSEN , KARIN LÖWENSTEIN CHRISTENSEN , PEDER MOHR OLSEN
IPC分类号： A61J3/00 , A61J3/06 , A61J7/00 , A61K9/00 , A61K9/28 , A61K31/19 , A61K31/593
摘要： tablete contendo cálcio, e, cassete para dispensar dose. a presente invenção diz respeito a uma composição nutracêutica e/ou farmacêutica para uso oral contendo um composto contendo cálcio. a composição está na forma de tabletes que são planejados de modo que tenham um sabor e paladar deixada na boca aceitáveis, com o qual os tabletes são mastigáveis ou sugáveis e ao mesmo tempo os tabletes satisfazem as exigências com respeito ás propriedades técnicas de modo a garantir que os tabletes possam ser dispensados por meio de uma máquina dispensadora de dose. em uma realização preferida, o tablete compreende carbonato de cálcio e sorbitol tamanho médio de partícula de 38 a 110 mícrons, em uma outra realização, os tabletes compreendem carbonato de cálcio e vitamina d como ingredientes ativos.

92. 发明专利

BRPI0619572B1 método para a preparação de um carbonato de cálcio revestido com película, método para a preparação de tablete farmacêutico ou nutricional compreendendo um carbonato de cálcio revestido com película, carbonato de cálcio revestido com película e composição farmacêutica ou nutricional 未知
公开(公告)号：BRPI0619572B1
公开(公告)日：2020-11-17
申请号：BRPI0619572
申请日：2006-12-07
申请人： NYCOMED PHARMA AS , NYCOMED DANMARK APS , TAKEDA AS , TAKEDA NYCOMED AS
发明人： JAN YNGVAR PIENE
IPC分类号： A61K9/00 , A23L29/30 , A23L33/15 , A23L33/155 , A23L33/16 , A61K9/16 , A61K9/20 , A61K33/06 , A61K33/10
摘要： métodos para a preparação de um composto contendo cálcio pelo menos parcialmente revestido com película e/ou granulado, de uma composição e de um tablete, composto contendo cálcio pelo menos parcialmente revestido com película ou granulado, composição farmacêutica ou nutricional, e, método para melhorar as propriedades sensoriais de um composto contendo cálcio. os compostos contendo cálcio foram pelo menos parcialmente revestidos com película ou granulados com uma substância solúvel em água e uma substância polimérica solúvel em água e uso de tais compostos revestidos em composições farmacêuticas. os compostos pelo menos parcialmente revestidos com película e/ou contendo cálcio granulado provaram-se adequados para a preparação de tabletes tendo uma carga muito elevada de cálcio elementar e um tamanho convenientemente pequeno. uma carga de medicamento de cerca de 96% ou mais é obtida em tabletes da invenção, que têm suficientes propriedades mecânicas e organolépticas.

93. 发明专利

SA112330549B1 مادة حاملة للكولاجين ملفوفة 未知
公开(公告)号：SA112330549B1
公开(公告)日：2016-03-02
申请号：SA112330549
申请日：2012-05-26
申请人： TAKEDA AS , TAKEDA NYCOMED AS , NYCOMED PHARMA AS
发明人： INGRID BLANKA , POUL BERTELSEN , PERNILLE DYBENDAL PEDERSEN , WOLFGANG SCHÖNHOFER , HENRIK NEUSCHAFER LARSEN , HENRIK BRÆNDER
摘要： يتعلقالاختراعالحاليبعمليةلتحضيرمادةحاملةللكولاجين collagen carrier ملفوفة rolled ومضغوطة compressed وعمليةلفك un-rolling المادةالحاملةللكولاجينالملفوفة rolled collagen carrier والمضغوطة compressed المذكورة. وتكونالمادةالحاملةللكولاجينالملفوفةوالمضغوطةالمذكورةسهلةالاستخدامفيالجراحةالانتشاريةلأقلدرجةممكنة. كمايتعلقالاختراعبمادةحاملةللكولاجينملفوفةومضغوطةلاستخدامهافيالوقاية prevention منأوعلاجالجروح treatment injury المصاحبةلإجراءجراحةانتشاريةبأقلدرجةممكنة. شكل 1.

94. 发明专利

CA2631821C PRE-COMPACTED CALCIUM-CONTAINING COMPOSITIONS 未知
公开(公告)号：CA2631821C
公开(公告)日：2014-03-11
申请号：CA2631821
申请日：2006-12-07
申请人： NYCOMED PHARMA AS , NYCOMED DANMARK APS
发明人： BERTELSEN POUL EGON , OLSEN PEDER MOHR
IPC分类号： A61K9/16 , A23L1/09 , A23L1/304 , A23L33/155 , A61K9/20 , A61K33/06 , A61K47/26
摘要： A pre-compacted materiel comprising one or more calcium-containing compounds and one or more sugar alcohols, wherein the calcium-containing compound having a polycrystallic porous structure. The pre-compacted material is preferably obtained by roller compaction and is suitable for use in the further processing of the pre-compacted material into composition like e.g. tablets.

95. 发明专利

IL229446D0 Rolled collagen carrier 未知
公开(公告)号：IL229446D0
公开(公告)日：2014-01-30
申请号：IL22944613
申请日：2013-11-14
申请人： TAKEDA NYCOMED AS , NYCOMED PHARMA AS
IPC分类号： A61F20060101
摘要： The invention relates to a process for the preparation of a rolled compressed collagen carrier and a process for un-rolling said rolled compressed collagen carrier. Said rolled compressed collagen carrier is ready for use in minimally invasive surgery. The invention also relates to a rolled compressed collagen carrier for use in the prevention or treatment of injury associated with performing minimally invasive surgery.

96. 发明专利

NZ592528A IMPROVED DISSOLUTION STABILITY OF CALCIUM CARBONATE TABLETS 未知
公开(公告)号：NZ592528A
公开(公告)日：2013-05-31
申请号：NZ59252809
申请日：2009-11-17
申请人： NYCOMED PHARMA AS
发明人： OLSEN PEDER MOHR , BERTELSEN POUL EGON , THISTED THOMAS , AAGE HENRIK RAVN
IPC分类号： A61K33/06 , A61K9/20
摘要： 592528 Disclosed herein is a method for the preparation of a tablet comprising at least 50% w/w of calcium carbonate, the method comprising: providing a particulate composition comprising a) calcium carbonate, b) a binding sugar alcohol selected from sorbitol or isomalt, or combinations thereof c) a 5 non-binding sugar alcohol selected from mannitol, maltitol or xylitol, or combinations thereof and d) one or more pharmaceutically acceptable excipients, which is not magnesium stearate, calcium stearate or stearic acid; and compressing said composition using a tabletting machine equipped with at least one pair of punches and dies, wherein the pair of punches and die before filling 10 the die with said particulate composition is sprayed with a composition comprising a lubricant selected from magnesium stearate, calcium stearate or stearic acid or combinations thereof. Additionally disclosed are calcium carbonate tablets, for example a tablet containing: 70-75% w/w of calcium carbonate, 4-25% w/w of one or more binding sugar alcohols selected from sorbitol or isomalt or combinations thereof, 4-25% w/w of one or more non-binding sugar alcohols selected from mannitol, maltitol or xylitol, or combinations thereof, 2-10% w/w of one or more pharmaceutically acceptable excipients, wherein said excipients are not lubricants including magnesium stearate, calcium stearate, or stearic acid, 0-2% w/w of one or more flavours and/or artificial sweeteners, 0.001-0.01% w/w of magnesium stearate, calcium stearate or stearic acid with the proviso that the total amount corresponds to 100% w/w, and wherein the content of magnesium stearate, calcium stearate or stearic acid solely is present on the outermost (external) surface of the tablet.

97. 发明专利

DK1320356T4 Fremstilling af vitaminemulsioner og koncentrater deraf 未知
公开(公告)号：DK1320356T4
公开(公告)日：2011-09-12
申请号：DK01967545
申请日：2001-09-20
申请人： NYCOMED PHARMA AS
发明人： SCHLYTER JIMMY HIRSCHSPRUNG , PIENE JAN YNGVAR
IPC分类号： A61K9/107 , A23L27/00 , A23L33/15 , A61K9/00 , A61K31/10 , A61K31/55 , A61K31/5513 , A61K31/58 , A61K47/14 , A61P3/02

98. 发明专利

GEP20104896B CHEWABLE, SUCKABLE AND SWALLOWABLE TABLET CONTAINING A CALCIUM-CONTAINING COMPOUND AS AN ACTIVE SUBSTANCE 未知
公开(公告)号：GEP20104896B
公开(公告)日：2010-02-25
申请号：GEAP2005009802
申请日：2005-05-24
申请人： NYCOMED PHARMA AS
发明人： SØRENSEN DINA WULFF , CHRISTENSEN KARIN LÖWENSTEIN , OLSEN PEDER MOHR
IPC分类号： A61K9/00 , A61J3/06 , A61K9/28 , A61K31/19 , A61K31/593
摘要： A tablet contains a calcium-containing compo¬und and pharmaceutically acceptable sugar syrup with a mean particle size of 38 or 110 microns.

99. 发明专利

IL157097A SUSPENSION COMPRISING FIBRINOGEN,THROMBIN AND ALCOHOL, METHOD FOR PREPARING SUCH A SUSPENSION, METHOD FOR COATING A CARRIER WITH SUCH A SUSPENSION, METHOD OF DRYING A COATING OF A CARRIER AND COATED COLLAGEN SPONGE 未知
公开(公告)号：IL157097A
公开(公告)日：2009-12-24
申请号：IL15709703
申请日：2003-07-24
申请人： NYCOMED PHARMA AS
IPC分类号： A61K9/16 , A61K38/46 , A61K38/48 , A61K47/34 , A61K47/36 , A61K47/38 , A61K47/42 , A61L20060101 , A61L15/16 , A61L15/22 , A61L15/32 , A61L15/42 , A61L15/44 , A61L15/64 , A61L24/00 , A61L24/08 , A61L24/10 , A61L27/00 , A61L31/04 , A61P7/04 , A61P41/00 , C08H1/06 , C08J20060101 , C08J9/30 , C08L20060101 , C08L89/06
摘要： The present invention relates to a solid composition useful for tissue gluing, tissue sealing and haemostasis consisting essentially of a) a carrier which has at least one of the following physical properties: elasticity module in the range of 5-100 N/cm, density of 1-10 mg/cm 3 , chamber diameter of more than 0.75 mm and less than 4 mm and/or having a chamber diameter average below 3 mm and evenly distributed and fixed upon said carrier, b) solid fibrinogen, and c) solid thrombin. The carrier is a biodegradable polymer such as a polyhyaluronic acid, polyhydroxy acid, e.g. lactic acid, glucolic acid, hydroxybutanoic acid, a cellulose, gelatine or collagen, such as a collagen sponge, e.g. a collagen sponge consisting essentially of collagen type I fibres. The fibrinogen and thrombin are preferably human, purified from a natural source, or transgenic or recombinant human fibrinogen and/or thrombin. In a preferred embodiment the composition does not comprise any antifibronolytic agent such as aprotinin, µ-aminocaproic acid or ±2-antiplasmin,

100. 发明专利

UA88943C2 БЫСТРЫЙ СПОСОБ ВЛАЖНОГО ГРАНУЛИРОВАНИЯ ДЛЯ ПОЛУЧЕНИЯ КОМПОЗИЦИЙ, КОТОРЫЕ СОДЕРЖАТ КАЛЬЦИЙ 未知
公开(公告)号：UA88943C2
公开(公告)日：2009-12-10
申请号：UAA200709809
申请日：2006-02-02
申请人： NYCOMED PHARMA AS
发明人： BERTELSEN POUL EGON , OLSEN PEDER MOHR , NIELSEN CARSTEN MARTINI , TOLLESHAUG MAGNUS WILHELM
IPC分类号： A61K9/16 , A61K9/20 , A61K33/06
摘要： Изобретениекасаетсяспособаполучениягранулята, которыйсодержиткарбонаткальциякакактивноевещество, которыйвключает: и) загрузкув камерудлягранулированиякомпозиции, котораясодержиткарбонаткальция, іиіи) влажноегранулированиекомпозициис грануляционнойжидкостью, котораясодержитфармацевтическиприемлемыйсвязующийагентв камередлягранулирования, котораяобеспечиваетпротеканиеэтогопроцесса, напротяжениимаксимум 30 сек., гдекамерадлягрануляциисодержитрядножей, икомпозицияпроходитчерезкамерудлягрануляцииблагодарясилетяжести, іиіиіи) высушиваниеполученноготакимобразомвлажногогранулята.

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