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    • 97. 发明申请
    • Optical magnetometer array and method for making and using the same
    • 光学磁力计阵列及其制造和使用方法
    • US20070167723A1
    • 2007-07-19
    • US11319792
    • 2005-12-29
    • Chang-Min ParkShriram Ramanathan
    • Chang-Min ParkShriram Ramanathan
    • G01R33/02A61B5/05
    • G01R33/032B82Y30/00G01R33/0322G01R33/24
    • An embodiment of the invention relates to a device comprising an array of optical magnetometers. The magnetometers comprise se a light source, a container having a chamber filled with an atomic vapor, and a photo detector capable of detecting optical properties of the atomic vapor. The substrate and the array of the magnetometers are designed such that the magnetometers are able to detect weak magnetic fields. Also, the magnetometers are capable of detecting distinct portions of a magnetic field, such as a non-uniform magnetic field, using a single or a plurality of the magnetometers in the array simultaneously. Other embodiment of the invention include methods of making a device that comprises an array of magnetometers and methods of detecting a magnetic field using the device. The device and method can be used in medical diagnostics, such as detecting biomagnetic activities of the human's heart and brain.
    • 本发明的实施例涉及一种包括光学磁力计阵列的装置。 磁力计包括光源,具有填充有原子蒸气的室的容器和能够检测原子蒸气的光学性质的光电检测器。 磁性计的基板和阵列被设计成使得磁力计能够检测弱磁场。 此外,磁力计能够同时使用阵列中的单个或多个磁力计来检测磁场的不同部分,例如不均匀的磁场。 本发明的其他实施例包括制造包括磁力计阵列的装置的方法和使用该装置检测磁场的方法。 该装置和方法可用于医学诊断,例如检测人类心脏和脑的生物磁性活动。
    • 100. 发明申请
    • Device, method, and system for separation and detection of biomolecules and cells
    • 用于分离和检测生物分子和细胞的装置,方法和系统
    • US20070114180A1
    • 2007-05-24
    • US11281891
    • 2005-11-18
    • Shriram RamanathanChang-Min Park
    • Shriram RamanathanChang-Min Park
    • C02F1/48
    • G01N33/553B82Y15/00B82Y25/00B82Y30/00C02F2209/36G01N33/54326G01N33/5438G01N33/569
    • Embodiments of the invention relate to device, method, and system for separation and/or detection of biological cells and biomolecules using micro-channels, magnetic interactions, and magnetic tunnel junctions. The micro-channels can be integrated into a microfluidic device that may be part of an integrated circuit. Magnetic interactions used for the separation are created, in part, by magnetic stripes associated with the micro-channels. Detection of biological cells and biomolecules is effectuated by a magnetic tunnel junction sensor that comprises two ferromagnetic layers separated by a thin insulating layer. The magnetic tunnel junction sensor can be integrated into a silicon based device, such a microfluidic device, an integrated circuit, or a microarray to achieve rapid and specific separation and/or detection of biomolecules and cells.
    • 本发明的实施方案涉及使用微通道,磁相互作用和磁性隧道结分离和/或检测生物细胞和生物分子的装置,方法和系统。 微通道可以集成到可以是集成电路的一部分的微流体装置中。 用于分离的磁相互作用部分地由与微通道相关联的磁条产生。 生物细胞和生物分子的检测由磁隧道结传感器实现,磁传感器包括由薄绝缘层分隔的两个铁磁层。 磁性隧道结传感器可以集成到基于硅的装置,如微流体装置,集成电路或微阵列中,以实现生物分子和细胞的快速和特异性分离和/或检测。