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91. 发明申请

WO2008106105A3 SPINE PLATE WITH BONE SCREW RELIEF AREA 审中-公开
标题翻译：脊椎螺钉松紧带
公开(公告)号：WO2008106105A3
公开(公告)日：2008-10-23
申请号：PCT/US2008002486
申请日：2008-02-26
申请人： LIFE SPINE INC , BUTLER MICHAEL S , MILELLA MICHAEL J
发明人： BUTLER MICHAEL S , MILELLA MICHAEL J
IPC分类号： A61B17/88
CPC分类号： A61B17/8052 , A61B17/7059 , A61B17/8605
摘要： A spina plate defines a body having a posterior surface or side and an anterior surface or side The body also has a pair of bone screw bores for each vertebra to which the spine plate will be attached The bone screw bores extend between the posterior side and the anterior side A relief area is provided between each pair of bone screw bores in the anterior surface of the body The relief area opens to both bone screw bores to allow displacement of the bone screw when entering the respective bone screw bore The relief area also opens to both bone screw bores to permit an instrument to be received therein to remove a bone screw from one of the bone screw bores.
摘要翻译：脊柱板限定具有后表面或侧面以及前表面或侧面的主体身体还具有用于每个椎骨的一对骨螺钉孔，脊椎板将被附接到该骨螺钉孔。骨螺钉孔在后侧和前侧在身体的前表面中的每对骨螺钉孔之间设置有一个释放区域。该释放区域向两个骨螺钉孔开口以允许骨螺钉在进入相应的骨螺钉孔时移位。救济区域还打开两个骨螺钉孔允许仪器被接纳在其中以从其中一个骨螺钉孔去除骨螺钉。

92. 发明申请

WO2007098188A3 STRUCTURE FOR JOINING AND RETAINING MULTI-PART ORTHOPEDIC IMPLANTS 审中-公开
标题翻译：用于加工和保留多部分对位植入物的结构
公开(公告)号：WO2007098188A3
公开(公告)日：2008-01-31
申请号：PCT/US2007004482
申请日：2007-02-21
申请人： LIFE SPINE INC , BUTLER MICHAEL S , MILELLA MICHAEL J JR
发明人： BUTLER MICHAEL S , MILELLA MICHAEL J JR
IPC分类号： A61F2/30
CPC分类号： A61F2/4465 , A61B17/7059 , A61F2002/30331 , A61F2002/3038 , A61F2002/305 , A61F2002/30604 , A61F2002/30772 , A61F2002/30904 , A61F2002/448 , A61F2220/0025 , A61F2220/0033
摘要： An orthopedic implant structure is provided for joining and retaining components of a multi-part orthopedic device. The orthopedic implant joining and retaining structure may be embodied in two or more components of the multi-part orthopedic device. In one form, the multi-part orthopedic implant structure is a resilient snap structure (36) such as a resilient flange (50) in one part (12a) and a channel structure (34) formed in another part (12b) of an orthopedic implant (10). A channel (40) of the channel structure (34) may have a cavity (42) formed at a rear of the channel (40) that accepts a configured lip (52) formed on an end of the resilient flange (50). According to another embodiment, the retaining structure includes resilient snap flanges (202) formed on an interconnection component (166) of the multi part orthopedic implant (160). A corresponding bore (198) in another part (164) of the multi-part orthopedic implant (160) receives the interconnection component (166).
摘要翻译：提供矫形植入物结构用于连接和保持多部分矫形装置的部件。矫形植入物接合和保持结构可以体现在多部分矫形装置的两个或更多个部件中。在一种形式中，多部分矫形植入物结构是弹性卡扣结构（36），例如在一个部分（12a）中的弹性凸缘（50）和形成在矫形外科的另一部分（12b）中的通道结构（34）植入物（10）。通道结构（34）的通道（40）可以具有形成在通道（40）的后部的空腔（42），该空腔接纳形成在弹性凸缘（50）的端部上的构造的唇缘（52）。根据另一个实施例，保持结构包括形成在多部件矫形植入物（160）的互连部件（166）上的弹性卡扣凸缘（202）。多部分整形外科植入物（160）的另一部分（164）中的对应孔（198）接收互连部件（166）。

93. 发明申请

WO2007098188A2 STRUCTURE FOR JOINING AND RETAINING MULTI-PART ORTHOPEDIC IMPLANTS 审中-公开
标题翻译：用于加工和保留多部分对位植入物的结构
公开(公告)号：WO2007098188A2
公开(公告)日：2007-08-30
申请号：PCT/US2007/004482
申请日：2007-02-21
申请人： LIFE SPINE, LLC , BUTLER, Michael, S. , MILELLA, Michael, J., Jr.
发明人： BUTLER, Michael, S. , MILELLA, Michael, J., Jr.
IPC分类号： A61F2/30
CPC分类号： A61F2/4465 , A61B17/7059 , A61F2002/30331 , A61F2002/3038 , A61F2002/305 , A61F2002/30604 , A61F2002/30772 , A61F2002/30904 , A61F2002/448 , A61F2220/0025 , A61F2220/0033
摘要： An orthopedic implant structure is provided for joining and retaining components of a multi-part orthopedic device. The orthopedic implant joining and retaining structure may be embodied in two or more components of the multi-part orthopedic device. In one form, the multi-part orthopedic implant structure is a resilient snap structure (36) such as a resilient flange (50) in one part (12a) and a channel structure (34) formed in another part (12b) of an orthopedic implant (10). A channel (40) of the channel structure (34) may have a cavity (42) formed at a rear of the channel (40) that accepts a configured lip (52) formed on an end of the resilient flange (50). According to another embodiment, the retaining structure includes resilient snap flanges (202) formed on an interconnection component (166) of the multi part orthopedic implant (160). A corresponding bore (198) in another part (164) of the multi-part orthopedic implant (160) receives the interconnection component (166).
摘要翻译：提供矫形植入物结构用于连接和保持多部分矫形装置的部件。矫形植入物接合和保持结构可以体现在多部分矫形装置的两个或更多个部件中。在一种形式中，多部分矫形植入物结构是弹性卡扣结构（36），例如在一个部分（12a）中的弹性凸缘（50）和形成在矫形外科的另一部分（12b）中的通道结构（34）植入物（10）。通道结构（34）的通道（40）可以具有形成在通道（40）的后部的空腔（42），该空腔接纳形成在弹性凸缘（50）的端部上的构造的唇缘（52）。根据另一个实施例，保持结构包括形成在多部件矫形植入物（160）的互连部件（166）上的弹性卡扣凸缘（202）。多部分整形外科植入物（160）的另一部分（164）中的对应孔（198）接收互连部件（166）。

94. 发明申请

WO2005070165A2 PEDICLE SCREW CONSTRUCTS FOR SPINE FIXATION SYSTEMS 审中-公开
标题翻译：用于脊柱固定系统的螺钉螺钉结构
公开(公告)号：WO2005070165A2
公开(公告)日：2005-08-04
申请号：PCT/US2005/000898
申请日：2005-01-13
申请人： LIFE SPINE, LLC , BUTLER, Michael, S. , YOUSSEF, Jim, A. , HILIBRAND, Alan, S.
发明人： BUTLER, Michael, S. , YOUSSEF, Jim, A. , HILIBRAND, Alan, S.
IPC分类号： A61B17/56 , A61B17/58 , A61B17/70
CPC分类号： A61B17/7038 , A61B17/7032 , A61B17/7034 , A61B17/7037
摘要： A pedicle screw coupling construct (31, 120, 140, 191, 260) for a pedicle screw construct (30, 190, 286) provides fixation of angular orientation (β, γ, θ) thereof relative to a pedicle screw (32) independent of fixation of a received spinal rod (25, 170, 250, 280) to the coupling construct (31, 120, 140, 191, 260). The pedicle screw construct (30, 190, 286) forms one component or element in a spinal fixation system. The independent fixation coupling construct also provides for fixation of the angular orientation of the coupling construct while the coupling construct has received the spinal rod. In another form, a coupling head or construct (31, 120, 140, 191, 260) is configured to allow a pedicle screw shaft (42) to pass therethrough but retain the pedicle screw head (44) for rotation of the coupling head about the pedicle screw head. The coupling head or construct (31, 120, 140, 191, 260) is also configured to allow at least a 45° arc of pivot or articulation about a pedicle screw shaft (42) relative to a longitudinal axis of a spinal rod (25, 170, 250, 280) received in the body. This allows the head with a received spinal rod to fold, bend or pivot relative to the pedicle screw shaft, particularly to a greater degree than the prior art.
摘要翻译：用于椎弓根螺钉构造（30,190,286）的椎弓根螺钉联接构造（31,120,140,191,260）提供了其相对于角度方向（β，γ，θ）的固定与接收的脊柱杆（25,170,250,280）固定到联接构造（31,120,140,191,260）无关的椎弓根螺钉（32）。椎弓根螺钉结构（30,190,286）在脊柱固定系统中形成一个部件或元件。独立固定连接构造还提供了在连接构造已经接收脊柱杆时固定连接构造的角取向。在另一种形式中，联接头或构造（31,120,140,191,260）被构造成允许椎弓根螺钉杆（42）穿过，但保持椎弓根螺钉头（44）以使联接头围绕其旋转椎弓根螺钉头。联接头或结构（31,120,140,191,260）也构造成允许至少45°角，相对于容纳在身体中的脊柱杆（25,170,250,280）的纵向轴线围绕椎弓根螺钉杆（42）枢转或铰接弧形。这允许具有接收的脊柱杆的头部相对于椎弓根螺钉轴折叠，弯曲或枢转，特别是比现有技术更大的程度。

95. 发明申请

WO2005062902A2 STATIC & DYNAMIC CERVICAL PLATES AND CERVICAL PLATE CONSTRUCTS 审中-公开
标题翻译：静，动态宫颈板和宫颈板结构
公开(公告)号：WO2005062902A2
公开(公告)日：2005-07-14
申请号：PCT/US2004/043172
申请日：2004-12-22
申请人： LIFE SPINE, LLC , BUTLER, Michael, S. , WANG, Jeffrey, C.
发明人： BUTLER, Michael, S. , WANG, Jeffrey, C.
IPC分类号： A61B17/56 , A61B17/58 , A61B17/70 , A61B17/80
CPC分类号： A61B17/8047 , A61B17/7059 , A61B17/8023 , A61B17/8042
摘要： A cervical bone plate includes a graft window that allows access to and/or visualization of a bone graft area of the cervical spine after attachment of the present cervical plate to the vertebrae. The window is preferably, but not necessarily, sized for maximum exposure of the graft area and/or the vertebral body without compromising plate strength, particularly with respect to federal standards for such devices. The window is centrally positioned on the plate and is sized to provide alignment of the plate onto the vertebrae at the base of the vertebra fastener or screw holes of the plate. In a dynamic form of this cervical bone plate, the graft window expands and contracts with respective expansion and contraction of the dynamic plate after attachment to the vertebrae (i.e. "dynamizes"). In another form, a threecomponent dynamic bone plate is configured such that a middle component accepts an identical end component at both ends of the middle component. The end component is a 180° interchangeable part. The middle component and the end component have cooperating configurations and complementarily configured grooves that allow sliding movement between the middle component and the end components. A two-pillar construction provides a central window.
摘要翻译：颈椎骨板包括移植物窗口，该移植物窗口允许在将当前颈盘附接到椎骨后接近和/或可视化颈椎的骨移植物区域。该窗口优选但不是必须地确定尺寸，以使得移植物区域和/或椎体的最大暴露不会影响板强度，特别是关于这种设备的联邦标准。窗口位于板的中心位置，其大小设置为将板对准椎骨紧固件底部或板的螺钉孔处的椎骨。在该颈椎骨板的动态形式中，移植窗在附着于椎骨后（即“动态化”）随着动态板的相应膨胀和收缩而膨胀和收缩。在另一种形式中，构造一个三sh组件动态骨板，使得中间组件在中间组件的两端接受相同的端部组件。最终组件是180°; 可互换的部分。中间部件和端部部件具有配合结构和互补配置的凹槽，其允许中间部件和端部部件之间的滑动运动。双柱结构提供了一个中央窗口。

96. 发明申请

WO2005062900A2 DYNAMIC CERVICAL PLATES AND CERVICAL PLATE CONSTRUCTS 审中-公开
标题翻译：动态板和板式结构
公开(公告)号：WO2005062900A2
公开(公告)日：2005-07-14
申请号：PCT/US2004/043170
申请日：2004-12-22
申请人： LIFE SPINE, LLC , BUTLER, Michael, S. , MILLELA, Michael, J., Jr.
发明人： BUTLER, Michael, S. , MILLELA, Michael, J., Jr.
IPC分类号： A61B17/56 , A61B17/58 , A61B17/70 , A61B17/80
CPC分类号： A61B17/8047 , A61B17/7059 , A61B17/8023 , A61B17/8042
摘要： N-level internally dynamizing cervical plates and cervical plate constructs in accordance with the present principles, provide unconstrained sliding interconnection between the various plate components after installation on a cervical spine. A tongueand-groove configuration between the various plate segments provides a constant thickness over the dynamizing portions. Detents provided relative the tongue-andgroove portions allows the various plate components to be permanently joined, but movable relative to one another. Various bone screw anti-backing, anti-rotation or locking devices for cervical bone plates are also provided that allow releasable locking of bone screws relative to the cervical plate.
摘要翻译： N级内部动态化宫颈板和根据本原理的宫颈板构造，在安装在颈椎上之后，在各种板组件之间提供无约束的滑动互连。各个板段之间的舌槽构造在动力部分上提供恒定的厚度。相对于舌 - 槽部分设置的固定部允许各种板部件永久地连接，而可相对于彼此移动。还提供了用于颈骨板的各种骨螺钉抗背衬，防旋转或锁定装置，其允许骨螺钉相对于颈板的可释放地锁定。

97. 发明申请

WO2023091789A1 VERTEBRAL ENDPLATE SHAVER WITH HEIGHT ADJUSTABLE BLADES 审中-公开
公开(公告)号：WO2023091789A1
公开(公告)日：2023-05-25
申请号：PCT/US2022/050733
申请日：2022-11-22
申请人： LIFE SPINE, INC.
发明人： PREDICK, Daniel, P.
IPC分类号： A61B17/16
摘要： A vertebral endplate preparation (decorticating) tool (110) has height adjustable blades (136, 137) at a distal end (120) of a shaft assembly (114) for decorticating/shaving vertebral endplate material from spinal vertebrae, translates axial movement of a control rod of the shaft assembly of the vertebral endplate preparation tool with height adjustable blades into radial blade height change (extension and retraction) through a controller (113) of a handle assembly (112). The blades may also be configured for collecting and removing shaven vertebral endplate material. The blades controllably move outward radially from the distal end of the shaft assembly and controllably move inward radially into the distal end of the shaft assembly upon manipulation of the controller. Radial blade extension and retraction from the distal end may be accomplished via mutual angled dovetail features (138, 139, 148,149; 166, 167, 164, 165) of the blades and the distal end, or via pins (1100, 1101 ) of the distal end of the shaft assembly situated in angled slots (187, 188; 195, 196) of the blades.

98. 发明申请

WO2022271838A1 DETECTING AND SEGMENTING REGIONS OF INTEREST IN BIOMEDICAL IMAGES USING NEURAL NETWORKS 审中-公开
公开(公告)号：WO2022271838A1
公开(公告)日：2022-12-29
申请号：PCT/US2022/034541
申请日：2022-06-22
申请人： LIFE SPINE, INC.
发明人： BUTLER, Michael S. , NALLANI, Vishnu , JAYARAMAN, Sridhar , BADAM, Rupesh Kumar
IPC分类号： G06V10/25 , G06V10/26 , G06V10/82 , G06T7/00 , G06T2207/10081 , G06T2207/10088 , G06T2207/10121 , G06T2207/20081 , G06T2207/20084 , G06T2207/30012 , G06T7/0012 , G06T7/11 , G06V2201/03 , G06V2201/033
摘要： Systems and methods for detecting regions of interests (ROIs) in biomedical images are described herein. A computing system may identify a biomedical image having an ROI. The computer system may apply an object detection model to the biomedical image. The object detection model may generate a feature map using the biomedical image. The object detection model may generate an anchor box corresponding to a portion of the pixels in the feature map. The computing system may apply an instance segmentation model to identify a segment of the biomedical image within the anchor box corresponding to the ROI. The computer system may provide an output based on the segment to identify the ROI in the biomedical image.

99. 发明申请

WO2021112892A1 SPINAL FACET JOINT AND LAMINOPLASTY IMPLANT 审中-公开
公开(公告)号：WO2021112892A1
公开(公告)日：2021-06-10
申请号：PCT/US2020/014230
申请日：2020-01-18
申请人： LIFE SPINE, INC.
发明人： LAUF, Garrett, D. , COYNE, Matthew, S. , SAMUEL, Forrest
IPC分类号： A61F2/30 , A61F2/44 , A61B17/70
摘要： A spine implant is configured for use in spinal facet joint fixation or to connect distracted portions of a vertebral lamina in a laminopiasty through use or non-use of a spacer. One or two bone screw plates are angularly adjustable relative to a base plate for attachment by bone screws to vertebral bone. One form of the spine implant has a base plate, a first plate pivotally connected to the base plate for angular adjustment of the first plate relative to the base plate and configured to hold one or two bone screws for attaching the first plate to first vertebral bone, and a second plate configured to hold two bone screws for attaching the second plate to second vertebral bone. The second plate may be pivotally connected to the body for angular adjustment of the second plate relative to the base plate or fixed to the base plate at a predetermined angle.

100. 发明申请

WO2020251943A1 EXPANDABLE IMPLANT ASSEMBLY WITH COMPRESSION FEATURES 审中-公开
公开(公告)号：WO2020251943A1
公开(公告)日：2020-12-17
申请号：PCT/US2020/036809
申请日：2020-06-09
申请人： LIFE SPINE, INC.
发明人： PREDICK, Daniel , WOLTERS, Madeline , BUTLER, Michael S.
IPC分类号： A61F2/44 , A61F2/30
摘要： An expandable implant includes a base member, an adjustable member adjustably coupled to the base member and movable between a first, collapsed position, and a second, expanded position, a control assembly including a control shaft, wherein manipulation of the control shaft causes relative movement of the adjustable member relative to the base member, wherein the base member and the adjustable member are coupled together at least in part via the control assembly such that the control shaft is rotationally fixed relative to the base member and the adjustable member, and the adjustable member is resiliently compressible relative to the base member.

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