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    • 91. 发明授权
    • Preparation of N-substituted arylsulfonamides
    • N-取代芳基磺酰胺的制备
    • US4713489A
    • 1987-12-15
    • US820876
    • 1986-01-16
    • Gail H. BirumRichard F. Jansen
    • Gail H. BirumRichard F. Jansen
    • C07C311/15C07C143/79
    • C07C311/15
    • N-substituted arylsulfonamides which comprises the steps of (a) reacting an aryl hydrocarbon with chlorosulfonic acid to form a crude chlorosulfonation reaction product, (b) adding said crude reaction product to a mixture comprising an aliphatic amine, an alkali or alkaline earth metal hydroxide and water to form an amidation reaction mixture, (c) maintaining the temperature of the amidation reaction mixture at between about 50.degree. C. and 100.degree. C. and the pH at above about 7 with stirring for a period of time of up to about 2 hours, and optionally (d) separating the resulting N-substituted arylsulfonamide from the amidation reaction product.
    • N-取代的芳基磺酰胺,其包括以下步骤:(a)使芳基烃与氯磺酸反应以形成粗氯磺化反应产物,(b)将所述粗反应产物加入到包含脂族胺,碱金属或碱土金属氢氧化物 和水以形成酰胺化反应混合物,(c)将酰胺化反应混合物的温度保持在约50℃至100℃,pH高于约7,同时搅拌一段时间至多约 2小时,任选地(d)从酰胺化反应产物中分离得到的N-取代的芳基磺酰胺。
    • 97. 发明授权
    • Phosphate and phosphonate compounds
    • 磷酸盐和膦酸盐化合物
    • US4883892A
    • 1989-11-28
    • US260342
    • 1988-10-20
    • Thomas A. HardyEdward N. Walsh
    • Thomas A. HardyEdward N. Walsh
    • C07F9/40C08K5/5333
    • C08K5/5333C07F9/4006C07F9/4075
    • There are disclosed novel phosphorous-containing compounds including and derived from hydrogen phosphonates. The compounds of the present invention can be prepared by reacting a hydrogen phosphonate with: (a) an ethylene derivative in a Michael reaction, (b) an amine or amide and formaldehyde in a Mannich reaction, (c) an aldehyde or ketone, (d) a halogen, (e) carbon tetrachloride and an alkylamine, and (f) carbon tetrachloride and a hydroxyphosphonate. Halophosphonates produced according to procedure (d) can also be used in reactions with (a) alkylamines and (b) hydroxyphosphonates or epoxides to produce the compounds of the present invention.
    • 公开了包括并衍生自氢膦酸盐的新颖的含磷化合物。 本发明的化合物可以通过使膦酸氢钾与(a)迈克尔反应中的乙烯衍生物,(b)曼尼希反应中的胺或酰胺和甲醛反应制得,(c)醛或酮( d)卤素,(e)四氯化碳和烷基胺,和(f)四氯化碳和羟基膦酸盐。 根据方法(d)制备的卤代膦酸盐也可用于与(a)烷基胺和(b)羟基膦酸酯或环氧化物的反应中,以产生本发明的化合物。
    • 98. 发明授权
    • Phosphate and phosphonate compounds
    • 磷酸盐和膦酸盐化合物
    • US4883891A
    • 1989-11-28
    • US258536
    • 1988-10-17
    • Thomas A. HardyEdward N. Walsh
    • Thomas A. HardyEdward N. Walsh
    • C07F9/40C08K5/5333
    • C08K5/5333C07F9/4006C07F9/4075
    • There are disclosed novel phosphorous-containing compounds including and derived from hydrogen phosphonates. The compounds of the present invention can be prepared by reacting a hydrogen phosphonate with: (a) an ethylene derivative in a Michael reaction, (b) an amine or amide and formaldehyde in a Mannich reaction, (c) an aldehyde or ketone, (d) a halogen, (e) carbon tetrachloride and an alkylamine, and (f) carbon tetrachloride and a hydroxyphosphate. Halophosphonates produced according to procedure (d) can also be used in reactions with (a) alkylamines and (b) hydroxyphosphonates or epoxides to produce the compounds of the present invention.
    • 公开了包括并衍生自氢膦酸盐的新颖的含磷化合物。 本发明的化合物可以通过使膦酸氢钾与(a)迈克尔反应中的乙烯衍生物,(b)曼尼希反应中的胺或酰胺和甲醛反应制得,(c)醛或酮( d)卤素,(e)四氯化碳和烷基胺,和(f)四氯化碳和羟基磷酸酯。 根据方法(d)制备的卤代膦酸盐也可用于与(a)烷基胺和(b)羟基膦酸酯或环氧化物的反应中,以产生本发明的化合物。
    • 100. 发明授权
    • Phosphonate containing phosphonates
    • 含膦酸酯的膦酸酯
    • US4808744A
    • 1989-02-28
    • US20829
    • 1987-03-02
    • Thomas A. HardyEdward N. Walsh
    • Thomas A. HardyEdward N. Walsh
    • C07F9/40C08K5/5333
    • C08K5/5333C07F9/4006C07F9/4075
    • There are disclosed novel phosphorus-containing compounds including and derived from hydrogen phosphonates. The compounds of the present invention can be prepared by reacting a hydrogen phosphonate with: (a) an ethylene derivative in a Michael reaction, (b) an amine or amide and formaldehyde in a Mannich reaction, (c) an aldehyde or ketone, (d) a halogen, (e) carbon tetrachloride and an alkylamine, and (f) carbon tetrachloride and a hydroxyphosphonate. Halophosphonates produced according to procedure (d) can also be used in reactions with (a) alkylamines and (b) hydroxyphosphonates or epoxides to produce the compounds of the present invention.
    • 公开了包含并衍生自氢化膦酸盐的新型含磷化合物。 本发明的化合物可以通过使膦酸氢钾与(a)迈克尔反应中的乙烯衍生物,(b)曼尼希反应中的胺或酰胺和甲醛反应制得,(c)醛或酮( d)卤素,(e)四氯化碳和烷基胺,和(f)四氯化碳和羟基膦酸盐。 根据方法(d)制备的卤代膦酸盐也可用于与(a)烷基胺和(b)羟基膦酸酯或环氧化物的反应中,以产生本发明的化合物。