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1. 发明申请

WO2020242751A1 HYBRID LIGAND AND LIQUID CHROMATOGRAPHY STATIONARY PHASE INCLUDING HYBRID LIGAND 审中-公开
公开(公告)号：WO2020242751A1
公开(公告)日：2020-12-03
申请号：PCT/US2020/032349
申请日：2020-05-11
申请人： RESTEK CORPORATION
发明人： LU, Xiaoning , BARTLETT, Charles Vernon , FLANNERY, Connor , GREEN, Ahren Iver , REID, Terrence Scott
IPC分类号： B01J20/32 , B01J20/289 , B01D15/30 , B01D15/36 , B01D15/38
摘要： A composition includes a hybrid ligand. The hybrid ligand includes an amine group, an amide group or a sulfonamide group, and hydroxyl groups. A first method includes providing a solution containing a first polar analyte and a second polar analyte, applying the solution to a stationary phase including an immobilized hybrid ligand, applying an elution solvent to the stationary phase such that the first polar analyte and the second polar analyte pass through the stationary phase with different elution times, and collecting the first polar analyte at a first elution time and collecting the second polar analyte at a second elution time after the first elution time. A device of a packed column, a cartridge, a tube, a well plate, a membrane, or a planar thin-layer chromatography plate includes a solid support and a hybrid ligand coupled to the solid support. A second method forms an immobilized hybrid ligand.

2. 发明申请

WO2015031309A1 MULTICHAMBERED VIAL AND METHOD OF MIXING ANALYTICAL REFERENCE MATERIALS 审中-公开
标题翻译：多层玻璃和混合分析参考材料的方法
公开(公告)号：WO2015031309A1
公开(公告)日：2015-03-05
申请号：PCT/US2014/052629
申请日：2014-08-26
申请人： RESTEK CORPORATION
发明人： KANE, Thomas E. , GOSS, Michael A.
IPC分类号： B01L3/00
CPC分类号： B01L3/52 , B01L3/502 , B01L2200/0689 , B01L2200/16 , B01L2300/0832 , B01L2300/0867 , B01L2300/0874 , B01L2400/0478 , B01L2400/0487 , F17D1/08 , Y10T137/0318
摘要： A device for transferring and containing liquid and a mixing method are provided. The device includes a vial (200) having at least two storage lumens (260) extending axially along a vial body (210), a transfer channel (240) coupled to a distal end of each of the storage lumens, and a common chamber (232) in fluid communication with the storage lumens (260) via the transfer channels (240). The mixing method includes providing the device for transferring and containing liquid material; providing a fluid subunit (310) in each of the storage lumens, a distal gasket (320) sealing each of the fluid subunits (310) from a distal end (214) of the vial; providing a plunger assembly (1210) coupled to a proximal end (212) of the vial; and depressing the plunger assembly (1210). Depressing the plunger assembly (1210) forces the distal gaskets (320) into the gasket seats (250) and transfers the fluid subunits (310) into the common chamber (232) via the transfer channels (240).
摘要翻译：提供了一种用于转移和容纳液体的装置和混合方法。该装置包括具有至少两个沿着小瓶主体（210）轴向延伸的存储腔（260）的小瓶（200），耦合到每个存储腔的远端的传送通道（240）和公共室 232）经由传送通道（240）与存储腔（260）流体连通。混合方法包括提供用于转移和容纳液体材料的装置; 在每个所述存储腔中提供流体亚单元（310），远端密封垫（320），其与所述小瓶的远端（214）密封每个所述流体子单元（310）提供联接到所述小瓶的近端（212）的柱塞组件（1210）; 并压下柱塞组件（1210）。按压柱塞组件（1210）迫使远端垫圈（320）进入垫圈座（250），并通过传送通道（240）将流体子单元（310）传送到公共室（232）中。

3. 发明申请

WO2014110196A1 DISPENSING DEVICE AND METHOD 审中-公开
标题翻译：分配装置和方法
公开(公告)号：WO2014110196A1
公开(公告)日：2014-07-17
申请号：PCT/US2014/010771
申请日：2014-01-09
申请人： RESTEK CORPORATION
发明人： KANE, Thomas E. , JONES, Brian A.
IPC分类号： A61M5/19 , B65D81/32 , A61M5/24 , B01L3/00 , B01L3/02
CPC分类号： A61M5/19 , A61M5/2448 , A61M5/31511 , A61M2005/287 , B01L3/0217 , B01L3/527 , B01L2200/148 , B01L2300/0867 , B01L2400/0478 , B65D81/325
摘要： A dispensing device (600) is disclosed having an ampoule (100) with at least four storage lumens (120) extending axially along the length of an ampoule body (119), a mixing tip (126, 128) coupled to a distal end of the storage lumens (120), the mixing tip having at least four gasket seats formed therein, each gasket seat (431) corresponding to one of the storage lumens, and an outlet lumen (128) in fluid communication with the storage lumens.
摘要翻译：公开了一种分配装置（600），其具有安瓶（100），其具有至少四个沿着安瓿主体（119）的长度轴向延伸的存储腔（120），混合尖端（126,128）所述储存腔（120），所述混合尖端具有形成在其中的至少四个垫圈座，与所述存储腔中的一个相对应的每个垫圈座（431）和与所述储存腔流体连通的出口腔（128）。

4. 发明申请

WO2011081653A1 GAS CHROMATOGRAPHY INLET LINERS AND SAMPLE PATH CONTAINERS 审中-公开
标题翻译：气体色谱入口和样品路径容器
公开(公告)号：WO2011081653A1
公开(公告)日：2011-07-07
申请号：PCT/US2010/003175
申请日：2010-12-15
申请人： RESTEK CORPORATION , JONES, Brian, A. , GROSSMAN, Scott, L. , STROHM, Valerie, S. , KANE, Thomas, E.
发明人： JONES, Brian, A. , GROSSMAN, Scott, L. , STROHM, Valerie, S. , KANE, Thomas, E.
IPC分类号： B01D53/02
CPC分类号： G01N33/00 , B01L3/50 , B01L2200/143 , B01L2200/147 , B01L2300/0832 , B05D1/18 , G01K13/00 , G01N30/04 , G01N2030/126 , G01N2030/167
摘要： A container used for chromatographic sample analysis has (a) at least one silica uppermost layer, which is deposited onto the container using a liquid phase deposition process, and, optionally, (b) at least one indicator present in at least part of the at least one silica uppermost layer for visually distinguishing the container from other containers, and/or determining the "use status" of the container, and/or identifying the proper orientation of the container when it is to be put in use, and/or providing a means of decoration, identification, or counterfeit detection. In one preferred embodiment, the indicator is thermochromic. In another preferred embodiment, the indicator is photochromic.
摘要翻译：用于色谱样品分析的容器具有（a）至少一个二氧化硅最上层，其使用液相沉积工艺沉积到容器上，并且任选地（b）至少一个指示剂存在于至少一部分至少一个二氧化硅最上层，用于将容器与其他容器视觉区分，和/或确定容器的“使用状态”，和/或在容器投入使用时识别容器的正确取向，和/或提供一种装饰，鉴定或假冒检测的手段。在一个优选实施方案中，指示剂是热变色的。在另一个优选实施方案中，指示剂是光致变色的。

5. 发明申请

WO2010096200A2 GAS CHROMATOGRAPHY INLET LINER HAVING AT LEAST ONE INDICATOR 审中-公开
标题翻译：气体色谱入口衬里具有至少一个指示器
公开(公告)号：WO2010096200A2
公开(公告)日：2010-08-26
申请号：PCT/US2010/000522
申请日：2010-02-23
申请人： RESTEK CORPORATION , JONES, Brian, A. , KANE, Thomas, E.
发明人： JONES, Brian, A. , KANE, Thomas, E.
IPC分类号： G01N30/16
CPC分类号： G01N30/12
摘要： A gas chromatography inlet liner comprises a glass tube formed by a glass wall, the glass wall having pore channels formed therein, and an indicator present in the pore channels in at least part of the inlet liner. The indicator may be any element, compound, dopant, or mixture additive that modifies color or transparency of the inlet liner.
摘要翻译：气相色谱入口衬套包括由玻璃壁形成的玻璃管，其中形成有孔隙通道的玻璃壁和存在于入口衬里的至少一部分中的孔通道中的指示器。指示剂可以是改变入口衬里的颜色或透明度的任何元素，化合物，掺杂剂或混合物添加剂。

6. 发明申请

WO2021216837A1 HIGH ASPECT RATIO VACUUM AIR SAMPLING ASSEMBLY 审中-公开
公开(公告)号：WO2021216837A1
公开(公告)日：2021-10-28
申请号：PCT/US2021/028591
申请日：2021-04-22
申请人： RESTEK CORPORATION
发明人： GOSS, Michael A. , HERRINGTON, Jason S. , KANE, Thomas E.
IPC分类号： G01N1/22 , G01N1/24
摘要： A high aspect ratio vacuum air sampling assembly is disclosed including a first canister module. The canister module includes a high aspect ratio conduit having an aspect ratio of at least 30:1, an inlet disposed at an inlet end of the conduit, and an outlet with an outlet valve disposed at an outlet end of the conduit. The outlet is in fluid communication with the inlet through an internal volume of the conduit. An air sampling train is attached to and in fluid communication with the inlet, and includes an inlet valve, a precision orifice, and a flow controller. The inlet valve and the outlet valve are configured to isolate the internal volume of the conduit from fluid communication with an external environment when the inlet valve and the outlet valve are closed. The assembly may further include a second canister module or more in sequence.

7. 发明申请

WO2017106604A1 RETICULATED ANNULAR CAPILLARY GAS CHROMATOGRAPHY COLUMN AND METHOD FOR FORMING RETICULATED ANNULAR CAPILLARY GAS CHROMATOGRAPHY COLUMN 审中-公开
标题翻译：网状毛细管气相色谱柱及网状毛细管气相色谱柱的制备方法
公开(公告)号：WO2017106604A1
公开(公告)日：2017-06-22
申请号：PCT/US2016/067105
申请日：2016-12-16
申请人： RESTEK CORPORATION
发明人： LAUTAMO, Roy M.A.
IPC分类号： G01N30/60
CPC分类号： B01D53/025 , B33Y10/00 , B33Y80/00 , G01N30/6043 , G01N30/6069
摘要： A reticulated annular capillary GC column (100) is disclosed including a capillary wall (102), a core (104) disposed within the capillary wall, an annulus (106) disposed between said capillary wall and said core, and vanes (108) disposed in said annulus. The vanes extend along the length (110) of the capillary wall for less than the length of the capillary wall. The vanes define a reticulated flow path (118) through the annulus. The vanes structurally support the core within the capillary wall. A method for forming the reticulated annular capillary GC column is disclosed including forming a preform master pattern by an additive manufacturing technique, the preform master pattern including a preform wall, a preform core, a preform annulus disposed between the preform wall and the preform core, and struts disposed in the preform annulus. A preform is cast from the preform master pattern, and the preform is drawn down, forming the reticulated annular capillary GC column.
摘要翻译：本发明公开了一种网状环形毛细GC气相色谱柱（100），其包括毛细管壁（102），布置在毛细管壁内的芯（104），布置在所述毛细管壁和所述毛细管壁芯和设置在所述环状空间内的叶片（108）。叶片沿着毛细管壁的长度（110）延伸的长度小于毛细管壁的长度。叶片限定了穿过环空的网状流动路径（118）。叶片结构上支撑毛细管壁内的核心。公开了一种用于形成网状环形毛细管GC柱的方法，包括通过增材制造技术形成预成形母模，该预成形母模包括预成形件壁，预成形件芯，布置在预成形件壁和预成形件芯之间的预成形件环形件，和设置在预制件环面中的支柱。预成型坯由预成型坯母模浇铸而成，预成型坯被拉下，形成网状环状毛细管气相色谱柱。

8. 发明申请

WO2011008273A1 FLOWMETER AND MANIFOLD THEREFOR 审中-公开
标题翻译：流量计及其分配
公开(公告)号：WO2011008273A1
公开(公告)日：2011-01-20
申请号：PCT/US2010/001971
申请日：2010-07-14
申请人： RESTEK CORPORATION , GROVE, William, D. , TARR, Brandon, A. , JOHNSTON, Gerald, W. , KANE, Thomas, E.
发明人： GROVE, William, D. , TARR, Brandon, A. , JOHNSTON, Gerald, W. , KANE, Thomas, E.
IPC分类号： G01F1/20
CPC分类号： G01F1/36 , G01F1/363
摘要： An acoustic displacement flowmeter for determining flow rate of a fluid has a fluid flow line defining a flow path for the fluid. The fluid flow line has an inlet and an outlet. A controllable valve is positioned along the fluid flow line for opening and closing the flow path as desired, and an acoustic displacement transducer having a fluid port is coupled to the fluid flow line upstream from the controllable valve. The outlet of the fluid flow line extends through a wall isolating fluid exhausted from the outlet of the fluid flow line from electrical and/or mechanical components residing inside the flowmeter, thereby preventing the exhausted fluid, if explosive, from contacting such electrical and/or mechanical components which may act as potential ignition sources. An acoustic displacement transducer (ADT) chamber wall is formed on the manifold body.
摘要翻译：用于确定流体流速的声位移流量计具有限定流体流动路径的流体流动线。流体流动管线具有入口和出口。沿着流体流动管线定位可控阀，以根据需要打开和关闭流路，并且具有流体端口的声位移传感器联接到可控阀上游的流体流动管线。流体流动管线的出口延伸通过流体流动管线出口从位于流量计内部的电气和/或机械部件排出的壁的隔离壁延伸，从而防止排出的流体（如果有爆炸性物质）接触这种电气和/或可能作为潜在点火源的机械部件。在歧管体上形成声位移传感器（ADT）室壁。

9. 发明申请

WO2010120371A1 SOLID ALIQUOTS OF MULTIRESIDUE METHOD SALTS FOR SOLID PHASE EXTRACTION APPLICATIONS 审中-公开
标题翻译：用于固相萃取应用的多种方法的固体浓度
公开(公告)号：WO2010120371A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/001131
申请日：2010-04-16
申请人： RESTEK CORPORATION , MOSESMAN, Neil, H. , JONES, Brian, A. , COCHRAN, Jack, W.
发明人： MOSESMAN, Neil, H. , JONES, Brian, A. , COCHRAN, Jack, W.
IPC分类号： B01D11/02
CPC分类号： G01N1/34 , G01N1/405
摘要： It is an object of the invention to improve the current QuEChERS technology. In one aspect of the invention, the buffer-salt powder mixture of the first stage of the QuEChERS process is compressed into a solid dosage form before it is used in the first stage of the QuEChERS process. Replacing the QuEChERS powders (the buffer-salt powder mixture of the first stage of the QuEChERS process) with solid aliquots eliminates the need for using centrifuge tubes for packaging the product.
摘要翻译：本发明的目的是改进目前的QuEChERS技术。在本发明的一个方面，QuEChERS过程的第一阶段的缓冲盐混合物在QuEChERS过程的第一阶段被用于固体剂型之前。用固体等分试样替代QuEChERS粉末（QuEChERS工艺第一阶段的缓冲盐粉末混合物），无需使用离心管来包装产品。

10. 发明申请

WO2004079031A2 METHOD FOR CHEMICAL VAPOR DEPOSITION OF SILICON ON TO SUBSTRATES FOR USE IN CORROSIVE AND VACUUM ENVIRONMENTS 审中-公开
标题翻译：用于腐蚀和真空环境的硅衬底的化学气相沉积方法
公开(公告)号：WO2004079031A2
公开(公告)日：2004-09-16
申请号：PCT/US2004/006764
申请日：2004-03-05
申请人： RESTEK CORPORATION , SMITH, David, Abbott , BARONE, Gary, A. , HIGGINS, Martin, E. , KENDALL, Bruce, R., F. , LAVRICH, David, J.
发明人： SMITH, David, Abbott , BARONE, Gary, A. , HIGGINS, Martin, E. , KENDALL, Bruce, R., F. , LAVRICH, David, J.
IPC分类号： C23C
CPC分类号： C23C16/4408 , B32B9/04 , C09D1/00 , C09D5/08 , C09D5/084 , C23C16/24 , C23C16/4401 , C23C16/45523
摘要： A method of passivating the surface of a substrate to protect the surface against corrosion, the surface effects on a vacuum environment, or both. The substrate surface is placed in a treatment environment and is first dehydrated and then the environment is evacuated. A silicon hydride gas is introduced into the treatment environment, which may be heated prior to the introduction of the gas. The substrate and silicon hydride gas contained therein are heated, if the treatment environment was not already heated prior to the introduction of the gas and pressurized to decompose the gas. A layer of silicon is deposited on the substrate surface. The duration of the silicon depositing step is controlled to prevent the formation of silicon dust in the treatment environment. The substrate is then cooled and held at a cooled temperature to optimize surface conditions for subsequent depositions, and the treatment environment is purged with an inert gas to remove the silicon hydride gas. The substrate is cycled through the silicon depositing step until the surface of the substrate is covered with a layer of silicon. The treatment environment is then evacuated and the substrate cooled to room temperature.
摘要翻译：钝化基板表面以保护表面免受腐蚀，表面对真空环境的影响或两者的方法。将基材表面放置在处理环境中，并首先脱水，然后将环境抽真空。将氢化硅气体引入处理环境中，其可以在引入气体之前被加热。如果在引入气体之前处理环境未被加热并加压以分解气体，则其中包含的基板和氢化硅气体被加热。在衬底表面上沉积一层硅。控制硅沉积步骤的持续时间以防止在处理环境中形成硅粉尘。然后将基底冷却并保持在冷却的温度下，以优化随后沉积的表面条件，并且用惰性气体吹扫处理环境以除去氢化硅气体。衬底通过硅沉积步骤循环，直到衬底的表面被一层硅覆盖。然后将处理环境抽真空并将基材冷却至室温。

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