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    • 3. 发明授权
    • Apparatus for analyzing blood
    • 用于分析血液的装置
    • US5741213A
    • 1998-04-21
    • US736822
    • 1996-10-25
    • Yasuhiro KouchiKaoru AsanoKen Ishihara
    • Yasuhiro KouchiKaoru AsanoKen Ishihara
    • A61B5/00G06K9/00
    • G06K9/00127A61B5/0059
    • An apparatus for analyzing blood includes an image capturing device for capturing an image including at least one object blood cell and an analyzer for analyzing the captured image as an image F(x, y) in an x-y coordinate system. The analyzer includes an edge calculator for calculating an edge intensity distribution E(x, y) representing an outline of the image F(x, y); a weight memory for storing in advance a weight distribution W(i, j) corresponding to an average outline of the object cell; an assessment value calculator for obtaining an assessment value C (x, y) at each point (x, y) by calculating a degree of correspondence between the edge intensity distribution E (x, y) and the weight distribution W(i, j) for each point (x, y); and an extractor for extracting a point (x, y) at which the assessment value C(x, y) is larger than a predetermined value, thereby determining that the object blood cell is present at the point (x, y). The apparatus is useful as a device for identifying the object blood cell.
    • 用于分析血液的装置包括用于捕获包括至少一个对象血细胞的图像的图像捕获装置和用于在x-y坐标系统中分析捕获图像作为图像F(x,y)的分析器。 分析器包括用于计算表示图像F(x,y)的轮廓的边缘强度分布E(x,y)的边缘计算器。 权重存储器,用于预先存储与所述对象单元的平均轮廓对应的权重分布W(i,j); 评估值计算器,用于通过计算边缘强度分布E(x,y)和权重分布W(i,j)之间的对应度来获得每个点(x,y)处的评估值C(x,y) 对于每个点(x,y); 以及提取器,用于提取评估值C(x,y)大于预定值的点(x,y),从而确定所述对象血细胞存在于所述点(x,y)处。 该装置可用作识别对象血细胞的装置。
    • 5. 发明申请
    • Medical diagnosis support computer system, computer program, and server computer
    • 医疗诊断支持计算机系统,计算机程序和服务器计算机
    • US20090177453A1
    • 2009-07-09
    • US12152593
    • 2008-05-15
    • Yasuhiro KouchiTakeo SaitouMasayoshi Seike
    • Yasuhiro KouchiTakeo SaitouMasayoshi Seike
    • G06G7/48G06F3/048
    • G16H50/50
    • A medical diagnosis support computer system for supporting diagnosis of a patient by a doctor, the system comprising: a display device; and a controller in communication with the display device, the controller comprising a processor configured to build a biological model representing biological functions of the patient on a computer, generate pathological condition information of the patient based on the biological model, display a doctor screen and a patient screen in a switchable manner on the display device; wherein the doctor screen is configured to simultaneously display a screen region for displaying the pathological condition information of the patient and a screen region for displaying one or more related information related to the patient; and the patient screen is configured to selectively display a display content between the pathological condition information of the patient and one or more related information related to the patient is disclosed.
    • 一种用于支持医生对患者的诊断的医疗诊断支持计算机系统,所述系统包括:显示装置; 以及与所述显示装置通信的控制器,所述控制器包括处理器,所述处理器被配置为在计算机上构建表示所述患者的生物功能的生物学模型,基于所述生物模型生成患者的病理状况信息,显示医生屏幕和 患者屏幕以可切换的方式在显示装置上; 其中所述医生画面被配置为同时显示用于显示患者的病理状况信息的屏幕区域和用于显示与患者相关的一个或多个相关信息的屏幕区域; 并且患者屏幕被配置为选择性地显示患者的病理状况信息和与患者相关的一个或多个相关信息之间的显示内容。
    • 6. 发明申请
    • BIOLOGICAL SIMULATION SYSTEM AND COMPUTER PROGRAM PRODUCT
    • 生物仿真系统和计算机程序产品
    • US20080288228A1
    • 2008-11-20
    • US12043752
    • 2008-03-06
    • Yasuhiro KouchiTakeo SaitouMasayoshi Seike
    • Yasuhiro KouchiTakeo SaitouMasayoshi Seike
    • G06F9/455G06F7/06G06F17/30
    • G09B23/30G16H50/50
    • With an object to seek parameters of a biological model corresponding to individual patents, the present invention provides a biological simulation system comprises an internal parameter set generating section which generates internal parameter sets constituting a biological model, a biological model computing section computing output of a biological model which emulates a biological response of a biological organ based on the generated internal parameter set, and a template database having a plurality of combinations of a reference output value of the biological model and an internal parameter set corresponding to the reference output value, wherein the internal parameter set generating section comprises a database referring means which selects a reference output approximate to an actual biological response from said template database and which selects an internal parameter set corresponding to the selected reference output value.
    • 本发明提供一种生物模拟系统,其特征在于,具备生成构成生物体模型的内部参数组的内部参数组生成部,生物体模型计算部, 模型,其基于所生成的内部参数集模拟生物器官的生物反应;以及模板数据库,其具有生物模型的参考输出值和对应于所述参考输出值的内部参数集合的多个组合,其中, 内部参数集生成部分包括数据库参考装置,其从所述模板数据库中选择近似于实际生物反应的参考输出,并且选择与所选择的参考输出值对应的内部参数集。
    • 7. 发明申请
    • Simulation system of function of biological organ
    • 生物器官功能模拟系统
    • US20070288216A1
    • 2007-12-13
    • US11805743
    • 2007-05-24
    • Yasuhiro KouchiTakeo SaitouMasayoshi Seike
    • Yasuhiro KouchiTakeo SaitouMasayoshi Seike
    • G06G7/60
    • G16H50/50G06F19/00
    • A simulation system for simulating a function of a biological organ using a biological model in which the function of the biological organ are represented by a mathematical model with a computer is provided. The present system receives input of time-series actual measurement data representing the biological response of a subject, estimates the biological response of the subject at a time point at which the measurement is not performed by using the input time-series actual measurement data, and generates time-series reference data representing the biological response of the subject. The present system further generates a virtual biological organ virtually constructed in a computer system using the times-series reference data. The virtual biological organ corresponds to the function of a biological organ of the subject.
    • 提供了一种使用生物器官功能模拟生物器官的功能的模拟系统,其中生物器官的功能由计算机的数学模型表示。 本系统接收表示对象生物学响应的时间序列实际测量数据的输入,通过使用输入的时间序列实际测量数据来估计未进行测量的时间点的对象的生物学响应,以及 生成表示对象的生物反应的时间序列参考数据。 本系统还使用时间序列参考数据生成虚拟构建在计算机系统中的虚拟生物器官。 虚拟生物器官对应于受试者的生物器官的功能。
    • 10. 发明申请
    • Biological simulation system and computer program product
    • 生物仿真系统和计算机程序产品
    • US20060282245A1
    • 2006-12-14
    • US11431961
    • 2006-05-11
    • Yasuhiro KouchiTakeo SaitouMasayoshi SeikeYasuhiro Naitou
    • Yasuhiro KouchiTakeo SaitouMasayoshi SeikeYasuhiro Naitou
    • G06G7/48G06G7/58
    • G09B23/28G16H50/50
    • With an object to seek parameters of a biological model corresponding to individual patients, the present invention provides a biological simulation system comprises an internal parameter set generating section which generates internal parameter sets constituting a biological model, and a biological model computing section computing output of a biological model which emulates a biological response of a biological organ based on the generated internal parameter set, wherein the internal parameter set generating section comprises a means for automatically generating a plurality of different internal parameter sets, and a selecting means which determines an approximation between a biological model output calculated applying the automatically generated internal parameter set and an actual biological response corresponding to said output and which selects an appropriate internal parameter set from a plurality of the generated internal parameter sets.
    • 本发明提供一种生物模拟系统,该生物模拟系统包括生成构成生物模型的内部参数集的内部参数集生成部,以及计算生物体模型计算部 生物模型,其基于所生成的内部参数集模拟生物器官的生物反应,其中所述内部参数组生成部分包括用于自动生成多个不同内部参数集的装置,以及选择装置,其确定a 计算的生物模型输出应用自动生成的内部参数集和对应于所述输出的实际生物反应,并且从多个生成的内部参数集中选择合适的内部参数集。