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    • 3. 发明授权
    • Embolic protection devices
    • 栓塞保护装置
    • US07217255B2
    • 2007-05-15
    • US10386071
    • 2003-03-10
    • William J. BoyleAndy E. DenisonBenjamin C. HuterScott J. HuterRichard S. StackKent C. B. StalkerChristopher TarapataJohn D. Whitfield
    • William J. BoyleAndy E. DenisonBenjamin C. HuterScott J. HuterRichard S. StackKent C. B. StalkerChristopher TarapataJohn D. Whitfield
    • A61M29/00
    • A61F2/013A61F2002/011A61F2002/015A61F2002/018A61F2230/0006A61F2230/0067A61F2230/008
    • An embolic protection device for use in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filtering assembly having a self-expanding strut assembly and a filter element attached thereto. In one embodiment, the filtering assembly is attached to the distal end of a guide wire and is deployed within the patient's vasculature as the guide wire is manipulated into the area of treatment. A restraining sheath placed over the filtering assembly in a coaxial arrangement maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician. Thereafter, the sheath can be retracted to expose the filtering assembly which will then self-expand within the patient's vasculature. Interventional devices can be delivered over the guide wire and any embolic debris created during the interventional procedure and released into the blood stream will enter the filtering assembly and be captured therein. Other embodiments include filtering assemblies attached to an outer tubular member and inner shaft member which apply axial force to the distal ends of the assembly to either expand or contract the struts as needed.
    • 一种用于血管中的栓塞保护装置,当在狭窄或闭塞区域进行介入手术以捕获可能在手术期间产生和释放到血流中的任何栓塞物质。 该装置包括具有自扩张支柱组件和附接到其上的过滤元件的过滤组件。 在一个实施例中,过滤组件附接到导丝的远端,并且当导丝被操纵进入治疗区域时,其被布置在患者的脉管系统内。 以同轴布置放置在过滤组件上方的限制护套将过滤组件保持在其收缩位置,直到其准备好由医师部署。 此后,护套可缩回以露出过滤组件,然后过滤组件将在患者的脉管系统内自我扩张。 介入装置可以在导丝上传送,并且在介入手术期间产生的并释放到血流中的任何栓塞碎片将进入过滤组件并被捕获在其中。 其他实施例包括附接到外部管状构件和内部轴构件的过滤构件,其向组件的远端施加轴向力,以根据需要来扩展或收缩支柱。
    • 4. 发明授权
    • Embolic protection devices
    • 栓塞保护装置
    • US06540722B1
    • 2003-04-01
    • US09490319
    • 2000-01-24
    • William J. BoyleAndy E. DenisonBenjamin C. HuterScott J. HuterRichard S. StackKent C. B. StalkerChristopher TarapataJohn D. Whitfield
    • William J. BoyleAndy E. DenisonBenjamin C. HuterScott J. HuterRichard S. StackKent C. B. StalkerChristopher TarapataJohn D. Whitfield
    • A61M2900
    • A61F2/013A61F2002/011A61F2002/015A61F2002/018A61F2230/0006A61F2230/0067A61F2230/008
    • An embolic protection device for use in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filtering assembly having a self-expanding strut assembly and a filter element attached thereto. In one embodiment, the filtering assembly is attached to the distal end of a guide wire and is deployed within the patient's vasculature as the guide wire is manipulated into the area of treatment. A restraining sheath placed over the filtering assembly in a coaxial arrangement maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician. Thereafter, the sheath can be retracted to expose the filtering assembly which will then self-expand within the patient's vasculature. Interventional devices can be delivered over the guide wire and any embolic debris created during the interventional procedure and released into the blood stream will enter the filtering assembly and be captured therein. Other embodiments include filtering assemblies attached to an outer tubular member and inner shaft member which apply axial force to the distal ends of the assembly to either expand or contract the struts as needed.
    • 一种用于血管中的栓塞保护装置,当在狭窄或闭塞区域进行介入手术以捕获可能在手术期间产生和释放到血流中的任何栓塞物质。 该装置包括具有自扩张支柱组件和附接到其上的过滤元件的过滤组件。 在一个实施例中,过滤组件附接到导丝的远端,并且当导丝被操纵进入治疗区域时,其被布置在患者的脉管系统内。 以同轴布置放置在过滤组件上方的限制护套将过滤组件保持在其收缩位置,直到其准备好由医师部署。 此后,护套可缩回以露出过滤组件,然后过滤组件将在患者的脉管系统内自我扩张。 介入装置可以在导丝上传送,并且在介入手术期间产生的并释放到血流中的任何栓塞碎片将进入过滤组件并被捕获在其中。 其他实施例包括附接到外部管状构件和内部轴构件的过滤构件,其向组件的远端施加轴向力,以根据需要来扩展或收缩支柱。
    • 6. 发明授权
    • Low profile sheathless embolic protection system
    • US06506203B1
    • 2003-01-14
    • US09740560
    • 2000-12-19
    • William J. BoyleRichard S. Stack
    • William J. BoyleRichard S. Stack
    • A61M2900
    • A61F2/013A61F2002/015A61F2002/018A61F2230/0006A61F2230/008
    • A system used in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region, which is capable of enabling a support device and filter supported thereon, to be inserted into the blood vessel and to cross the stenosis therein in a low profile without a sheath extending thereabout. The filter is adapted to filter the blood in the blood vessel. The system is further capable of enabling the support device and filter to be positioned distal to the interventional procedure site, and to be activated to expand at the distal location so as to enable the filter to capture any embolic material that may be created and released into the bloodstream during the interventional procedure. The system is also capable of enabling the support device and filter to be activated to contract to a return profile for enabling the filter to retain the embolic material captured therein and the removal of the support device and filter from the blood vessel. The system includes a filter, adapted to be deployed distal to the interventional procedure site, and to pass blood therethrough and capture embolic material which may be released into the blood in the blood vessel during the interventional procedure. A support device is adapted to support the filter, and to retain a low profile so as to enable the filter to be inserted into and cross the stenosis in the blood vessel, to a position distal to the interventional procedure site, without a sheath extending about the filter and the support device. The support device is further adapted to deform for expansion thereof into open position to enable the filter to capture embolic material, and to enable the collapsing thereof to retain the embolic material captured in the filter, and to enable removal of the support device and the filter. The system also includes a mechanism, connected to the support device, adapted to be activated so as to enable the support device to deform for expansion thereof.
    • 8. 发明授权
    • Guidewire with variable coil configuration
    • 导丝可变线圈配置
    • US6139511A
    • 2000-10-31
    • US106918
    • 1998-06-29
    • Scott J. HuterWilliam J. BoyleRichard S. Stack
    • Scott J. HuterWilliam J. BoyleRichard S. Stack
    • A61B5/00A61M25/09
    • A61M25/09A61M2025/09083
    • The present invention is directed to a guidewire having an elongate core member with a proximal section and a distal section. The distal section has at least one tapered segment, wherein the elongate core member tapers distally to a reduced diameter. Preferably, the tapered segments of the distal section of the elongate core member are marked with radiopaque markers to indicate where a tapered segment begins or ends. A proximal coil having a rectangular cross section and at least one distal coil having a round cross section are disposed around at least a portion of the distal section of the elongate core member. The proximal end of the proximal coil is attached to the distal section of the elongate core member. The distal coils can be made of a material that is radiopaque or non-radiopaque. If one of the distal coils is radiopaque, it may be made from a radiopaque material or it may be made of a hollow tube of non-radiopaque material that is filled with material that is at least partially radiopaque. The proximal end of the distal most coil is attached to the distal end of the proximal coil, and the distal end of the distal most coil is attached to the distal section of the elongate core member.
    • 本发明涉及一种具有细长芯部件的导丝,其具有近端部分和远端部分。 远侧部分具有至少一个锥形部分,其中细长芯部件向远端逐渐变细直径减小。 优选地,细长芯部件的远端部分的锥形部分用不透射线的标记标记,以指示锥形部分开始或结束的位置。 具有矩形截面的近端线圈和具有圆形横截面的至少一个远端线圈设置在细长芯部件的远端部分的至少一部分周围。 近端线圈的近端附接到细长芯构件的远端部分。 远侧线圈可以由不透射线或非不透射线的材料制成。 如果远端线圈之一是不透射线的,则其可以由不透射线材料制成,或者其可以由填充有至少部分不透射线的材料的非不透射线材料的中空管制成。 最远端线圈的近端附接到近端线圈的远端,并且最远端线圈的远端附接到细长芯构件的远端部分。