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1. 发明申请

WO2010070050A1 A DOSE SETTING ELEMENT FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE WITH A DOSE SETTING ELEMENT 审中-公开
标题翻译：用于药物递送装置的药剂设定元件和具有剂量设定元件的药物递送装置
公开(公告)号：WO2010070050A1
公开(公告)日：2010-06-24
申请号：PCT/EP2009/067417
申请日：2009-12-17
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , SMITH, Christopher James , CLAUGHTON, Timothy Giles
发明人： SMITH, Christopher James , CLAUGHTON, Timothy Giles
IPC分类号： A61M5/315 , G01F11/02 , A61M5/20
CPC分类号： G01F11/023 , A61M5/20 , A61M5/31555 , A61M5/3156 , A61M5/31563 , A61M5/3158 , A61M2005/2013 , A61M2005/208 , G01F11/027
摘要： The invention relates to a dose setting mechanism (1) for a drug delivery device (2), comprising a number of separate dose setting elements (3.1 to 3.n), wherein a dose volume and/or a dose number are/is set by moving at least one of the respective dose setting elements (3.1 to 3.n) from a stack position (I) to an initial position (II), and wherein a medicament dose volume is applied by moving at least one dose setting element (3.1 to 3.n) from the initial position (II) to a dispense position (III) and wherein the movement of the dose setting element (3.1 to 3.n) from the initial position (II) to the dispense position (III) is limited by at least a height (h) of the dose setting elements (3.1 to 3.n) in the initial position (II), wherein each dose setting element (3.1 to 3.n) comprises a plurality of bulges (B1 to Bm) on at least one surface side (S1), wherein the height (h) of each dose setting element (3.1 to 3.n) equals a sum of the thickness (D) of the dose setting element (3.1 to 3.n) and the bulge height (h1).
摘要翻译：本发明涉及一种用于药物输送装置（2）的剂量设定机构（1），其包括多个单独的剂量设定元件（3.1至3.n），其中设定剂量体积和/或剂量数量通过将各个剂量设定元件（3.1至3.n）中的至少一个从堆叠位置（I）移动到初始位置（II），并且其中通过移动至少一个剂量设定元件（ 3.1至3.n）从初始位置（II）到分配位置（III），并且其中剂量设定元件（3.1至3.n）从初始位置（II）到分配位置（III）的移动在初始位置（II）中受到剂量设定元件（3.1至3.n）的至少高度（h）的限制，其中每个剂量设定元件（3.1至3.n）包括多个凸起（B1至 Bm）在至少一个表面侧（S1），其中每个剂量设定元件（3.1至3.n）的高度（h）等于剂量设定元件（3.1至3.n）的厚度（D） 3.n）和凸起高度（h1）。

2. 发明申请

WO2011124634A3 CODED CAP FOR USE WITH A DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2011124634A3
公开(公告)日：2011-10-13
申请号：PCT/EP2011/055397
申请日：2011-04-07
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , CLAUGHTON, Timothy Giles
发明人： CLAUGHTON, Timothy Giles
IPC分类号： A61M5/32 , A61M5/24
摘要： A cap-fit differentiation means for use with a medication or drug delivery device (100, 206) is described. The cap (106,200) includes at least one first coding feature located on a surface (204) of the cap (106, 200), the at least one coding feature configured to interact with at least one second coding feature located on the drug delivery device (100, 206). When the first and second coding features interact, feedback is provided to a user. The feedback may include tactile and/or audible feedback. The second coding feature may alternatively be located on the cartridge (120) or cartridge holder (104).

3. 发明申请

WO2012055845A1 DRUG DELIVERY DEVICE AND METHOD FOR ASSEMBLING A DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置和用于组装药物递送装置的方法
公开(公告)号：WO2012055845A1
公开(公告)日：2012-05-03
申请号：PCT/EP2011/068603
申请日：2011-10-25
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , NODERER, Michael , CLAUGHTON, Timothy Giles , TERRY, Warren , VEASEY, Robert
发明人： NODERER, Michael , CLAUGHTON, Timothy Giles , TERRY, Warren , VEASEY, Robert
IPC分类号： A61M5/315
CPC分类号： A61M5/31533 , A61M5/30 , A61M5/31 , A61M5/3135 , A61M5/3146 , A61M5/31515 , A61M5/31568 , A61M2005/2407 , A61M2005/2488 , A61M2005/3125 , A61M2005/3126 , A61M2005/3151 , A61M2205/0222 , A61M2207/00
摘要： A drug delivery device (1) comprises a first component (6) and a second component (9), wherein a substance (16 ) e.g. grease, is provided on at least one of the first component (6) and the second component (9). An inner friction or viscosity of the substance (16) is great enough to stabilize at least one of the orientation and the position of the first component (6) and the second component (9) with respect to another. The inner friction or viscosity of the substance (16) is small enough to allow relative movement of the first component (6) and the second component (9) necessary for the intended operation of the device (1). Furthermore, a method for assembling a drug delivery device (1) is provided.
摘要翻译：药物递送装置（1）包括第一组分（6）和第二组分（9），其中物质（16）润滑脂被设置在第一部件（6）和第二部件（9）中的至少一个上。物质（16）的内部摩擦或粘度足够大以使第一部件（6）和第二部件（9）相对于另一部件的取向和位置中的至少一个稳定。物质（16）的内摩擦或粘度足够小以允许装置（1）的预期操作所需的第一部件（6）和第二部件（9）的相对移动。此外，提供了用于组装药物输送装置（1）的方法。

4. 发明申请

WO2011036134A3 ASSEMBLY AND INDICATOR FOR A DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置的组装和指示器
公开(公告)号：WO2011036134A3
公开(公告)日：2011-03-31
申请号：PCT/EP2010/063842
申请日：2010-09-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , PLUMPTRE, David , TERRY, Warren , VEASEY, Robert , JONES, Matthew , CLAUGHTON, Timothy Giles
发明人： PLUMPTRE, David , TERRY, Warren , VEASEY, Robert , JONES, Matthew , CLAUGHTON, Timothy Giles
IPC分类号： A61M5/145 , A61M5/315
摘要： An assembly for a drug delivery device (1), comprising a housing (2) having a proximal end and a distal end, a piston rod (8) and an indicator (13). The piston rod (8) is adapted to be displaced distally with respect to the housing (2) away from a proximal start position and towards a distal end position for delivering a drug (31). The indicator (13) is adapted for indicating at least two different operation conditions of the assembly, the indicator (13) being moveable with respect to the housing (2) from a first indication position for a first condition of the assembly into a second indication position for a second condition of the assembly. The piston rod (8) and the indicator (13) are configured to mechanically interact for converting movement of the piston rod (8) into movement of the indicator (13). A first detent (21) is provided which is configured to releasably secure the indicator (13) in the first indication position such that movement into the second indication position is allowed. A second detent (22) is provided which is configured to secure the indicator (13) in the second indication position such that movement into the first indication position is prevented.
摘要翻译：一种用于药物输送装置（1）的组件，包括具有近端和远端的壳体（2），活塞杆（8）和指示器（13）。活塞杆（8）适于相对于壳体（2）远离近侧开始位置并朝向远侧端部位置移位以输送药物（31）。指示器（13）适于指示组件的至少两个不同的操作状态，指示器（13）可相对于壳体（2）从用于组件的第一状态的第一指示位置移动到第二指示定位组件的第二个条件。活塞杆（8）和指示器（13）构造成机械地相互作用以将活塞杆（8）的运动转换为指示器（13）的运动。提供第一制动器（21），该第一制动器构造成将指示器（13）可释放地固定在第一指示位置，从而允许进入第二指示位置的运动。提供第二制动器（22），其构造成将指示器（13）固定在第二指示位置中，从而防止进入第一指示位置的运动。

5. 发明公开

EP2632512A1 DRUG DELIVERY DEVICE AND METHOD FOR ASSEMBLING A DRUG DELIVERY DEVICE 有权
标题翻译： DEVICE药品行政和方法用于组装装置给药的药物
公开(公告)号：EP2632512A1
公开(公告)日：2013-09-04
申请号：EP11781469.9
申请日：2011-10-25
申请人： Sanofi-Aventis Deutschland GmbH
发明人： NODERER, Michael , CLAUGHTON, Timothy Giles , TERRY, Warren , VEASEY, Robert
IPC分类号： A61M5/315
CPC分类号： A61M5/31533 , A61M5/30 , A61M5/31 , A61M5/3135 , A61M5/3146 , A61M5/31515 , A61M5/31568 , A61M2005/2407 , A61M2005/2488 , A61M2005/3125 , A61M2005/3126 , A61M2005/3151 , A61M2205/0222 , A61M2207/00
摘要： A drug delivery device (1) comprises a first component (6) and a second component (9), wherein a substance (16 ) e.g. grease, is provided on at least one of the first component (6) and the second component (9). An inner friction or viscosity of the substance (16) is great enough to stabilize at least one of the orientation and the position of the first component (6) and the second component (9) with respect to another. The inner friction or viscosity of the substance (16) is small enough to allow relative movement of the first component (6) and the second component (9) necessary for the intended operation of the device (1). Furthermore, a method for assembling a drug delivery device (1) is provided.
摘要翻译：的药物输送装置包括第一部件和第二部件，worin被设置在所述第一部件中的至少一个和所述第二组分的物质。该物质的内摩擦是大到足以稳定的取向和所述第一部件的位置和所述第二部件中的至少一个相对于彼此。所述物质的内摩擦足够小，以允许第一部件的相对运动，第二组分所必需的设备的预期的手术。进一步，提供了一种组装药物输送设备的方法。

6. 发明公开

EP2379139A1 A DOSE SETTING ELEMENT FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE WITH A DOSE SETTING ELEMENT 审中-公开
标题翻译：剂量设定方法的药物输送装置和药物递送装置随剂量设定
公开(公告)号：EP2379139A1
公开(公告)日：2011-10-26
申请号：EP09795418.4
申请日：2009-12-17
申请人： Sanofi-Aventis Deutschland GmbH
发明人： SMITH, Christopher James , CLAUGHTON, Timothy Giles
IPC分类号： A61M5/315 , G01F11/02 , A61M5/20
CPC分类号： G01F11/023 , A61M5/20 , A61M5/31555 , A61M5/3156 , A61M5/31563 , A61M5/3158 , A61M2005/2013 , A61M2005/208 , G01F11/027
摘要： The invention relates to a dose setting mechanism (1) for a drug delivery device (2), comprising a number of separate dose setting elements (3.1 to 3.n), wherein a dose volume and/or a dose number are/is set by moving at least one of the respective dose setting elements (3.1 to 3.n) from a stack position (I) to an initial position (II), and wherein a medicament dose volume is applied by moving at least one dose setting element (3.1 to 3.n) from the initial position (II) to a dispense position (III) and wherein the movement of the dose setting element (3.1 to 3.n) from the initial position (II) to the dispense position (III) is limited by at least a height (h) of the dose setting elements (3.1 to 3.n) in the initial position (II), wherein each dose setting element (3.1 to 3.n) comprises a plurality of bulges (B1 to Bm) on at least one surface side (S1), wherein the height (h) of each dose setting element (3.1 to 3.n) equals a sum of the thickness (D) of the dose setting element (3.1 to 3.n) and the bulge height (h1).

7. 发明授权

EP2632512B1 DRUG DELIVERY DEVICE AND METHOD FOR ASSEMBLING A DRUG DELIVERY DEVICE 有权
标题翻译：药物递送装置和组装药物递送装置的方法
公开(公告)号：EP2632512B1
公开(公告)日：2017-08-30
申请号：EP11781469.9
申请日：2011-10-25
申请人： Sanofi-Aventis Deutschland GmbH
发明人： NODERER, Michael , CLAUGHTON, Timothy Giles , TERRY, Warren , VEASEY, Robert
IPC分类号： A61M5/31 , A61M5/315 , A61M5/24
CPC分类号： A61M5/31533 , A61M5/30 , A61M5/31 , A61M5/3135 , A61M5/3146 , A61M5/31515 , A61M5/31568 , A61M2005/2407 , A61M2005/2488 , A61M2005/3125 , A61M2005/3126 , A61M2005/3151 , A61M2205/0222 , A61M2207/00

8. 发明公开

EP2555818A2 CODED CAP FOR USE WITH A DRUG DELIVERY DEVICE 审中-公开
标题翻译： CODED VERSCHLUSSKAPPE与药物管理局设备上使用
公开(公告)号：EP2555818A2
公开(公告)日：2013-02-13
申请号：EP11712571.6
申请日：2011-04-07
申请人： Sanofi-Aventis Deutschland GmbH
发明人： CLAUGHTON, Timothy Giles
IPC分类号： A61M5/32
CPC分类号： B67D99/00 , A61M5/3202 , A61M5/3213 , A61M2205/581 , A61M2205/582 , A61M2205/6036 , A61M2205/6045
摘要： A cap-fit differentiation means for use with a medication or drug delivery device (100, 206) is described. The cap (106,200) includes at least one first coding feature located on a surface (204) of the cap (106, 200), the at least one coding feature configured to interact with at least one second coding feature located on the drug delivery device (100, 206). When the first and second coding features interact, feedback is provided to a user. The feedback may include tactile and/or audible feedback. The second coding feature may alternatively be located on the cartridge (120) or cartridge holder (104).

9. 发明公开

EP2480268A2 ASSEMBLY AND INDICATOR FOR A DRUG DELIVERY DEVICE 有权
标题翻译： ANORDNUNG UND ANZEIGERFÜREINE ARZNEIMITTELABGABEVORRICHTUNG
公开(公告)号：EP2480268A2
公开(公告)日：2012-08-01
申请号：EP10762886.9
申请日：2010-09-21
申请人： Sanofi-Aventis Deutschland GmbH
发明人： PLUMPTRE, David , TERRY, Warren , VEASEY, Robert , JONES, Matthew , CLAUGHTON, Timothy Giles
IPC分类号： A61M5/145 , A61M5/315
CPC分类号： A61M5/31585 , A61M5/3146 , A61M5/31555 , A61M5/31593 , A61M2005/3125 , A61M2205/584
摘要： An assembly for a drug delivery device (1), comprising a housing (2) having a proximal end and a distal end, a piston rod (8) and an indicator (13). The piston rod (8) is adapted to be displaced distally with respect to the housing (2) away from a proximal start position and towards a distal end position for delivering a drug (31). The indicator (13) is adapted for indicating at least two different operation conditions of the assembly, the indicator (13) being moveable with respect to the housing (2) from a first indication position for a first condition of the assembly into a second indication position for a second condition of the assembly. The piston rod (8) and the indicator (13) are configured to mechanically interact for converting movement of the piston rod (8) into movement of the indicator (13). A first detent (21) is provided which is configured to releasably secure the indicator (13) in the first indication position such that movement into the second indication position is allowed. A second detent (22) is provided which is configured to secure the indicator (13) in the second indication position such that movement into the first indication position is prevented.
摘要翻译：一种用于药物输送装置的组件，包括具有近端和远端的壳体，活塞杆和指示器。活塞杆适于相对于壳体向远端远离近端起始位置并且朝向用于输送药物的远端位置移位。指示器适于指示组件的至少两个不同的操作条件，指示器可以相对于壳体从用于组件的第一状态的第一指示位置移动到组件的第二状态的第二指示位置。活塞杆和指示器构造成机械相互作用，以将活塞杆的运动转换成指示器的运动。提供了第一制动器，其构造成将指示器可释放地固定在第一指示位置，使得允许进入第二指示位置的移动。提供了第二制动器，其构造成将指示器固定在第二指示位置，使得防止进入第一指示位置的移动。

10. 发明授权

EP2480268B1 ASSEMBLY AND INDICATOR FOR A DRUG DELIVERY DEVICE 有权
标题翻译：安排及药物计费装置指标
公开(公告)号：EP2480268B1
公开(公告)日：2016-08-17
申请号：EP10762886.9
申请日：2010-09-21
申请人： Sanofi-Aventis Deutschland GmbH
发明人： PLUMPTRE, David , TERRY, Warren , VEASEY, Robert , JONES, Matthew , CLAUGHTON, Timothy Giles
IPC分类号： A61M5/145 , A61M5/315
CPC分类号： A61M5/31585 , A61M5/3146 , A61M5/31555 , A61M5/31593 , A61M2005/3125 , A61M2205/584

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