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1. 发明申请

WO2017089289A1 AUTO-INJECTOR 审中-公开
标题翻译：自动注射器
公开(公告)号：WO2017089289A1
公开(公告)日：2017-06-01
申请号：PCT/EP2016/078281
申请日：2016-11-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： WENDLAND, Stefan , HARMS, Michael
IPC分类号： A61M5/20 , A61M5/315
CPC分类号： A61M5/2033 , A61M2005/206 , A61M2005/31518
摘要： An auto-injector for delivering a liquid medicament comprising: a housing arranged to contain a syringe with a piston for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end intended to be applied against an injection site; and a telescopic plunger unit arranged between the piston and the distal end of the housing, the telescopic plunger unit comprising a telescopic frame and a spring element surrounding a plunger element, wherein the plunger element is fixed to a base of the telescopic plunger unit and the spring element is held in an initial compressed state by a compressive force exerted by the base of the telescopic plunger unit; wherein when the spring element is released, a tapering profile of the telescopic frame is configured to provide varying friction with extension such that resistance to telescopic extension decreases as spring force provided by the spring element decreases with increasing extension of the telescopic plunger unit.
摘要翻译：一种用于输送液体药剂的自动注射器，包括：壳体，其布置成容纳具有活塞的注射器，用于密封所述注射器并使所述药剂移位，所述壳体具有远端和近端，旨在应用于注射部位; 以及布置在所述活塞与所述壳体的所述远端之间的可伸缩柱塞单元，所述可伸缩柱塞单元包括伸缩框架和围绕柱塞元件的弹簧元件，其中所述柱塞元件固定至所述伸缩柱塞单元的基部，弹簧元件通过由伸缩柱塞单元的基部施加的压缩力而保持在初始压缩状态; 其中当所述弹簧元件被释放时，所述伸缩框架的锥形轮廓被配置为提供随着伸展而变化的摩擦，使得随着所述伸缩柱塞单元的伸长增加，由所述弹簧元件提供的弹簧力减小，所述伸缩伸长阻力减小。 p>

2. 发明申请

WO2017089263A1 A CAP FOR AN INJECTION DEVICE 审中-公开
标题翻译：注射装置的帽子
公开(公告)号：WO2017089263A1
公开(公告)日：2017-06-01
申请号：PCT/EP2016/078252
申请日：2016-11-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： WENDLAND, Stefan , HARMS, Michael
IPC分类号： A61M5/32
CPC分类号： A61M5/3202 , A61M5/3204
摘要： The present invention relates to a cap (12) for an injection device (10). The injection device comprises a body for holding a syringe having a needle extending from an end thereof. The cap is removably attachable to the body. The cap comprises an actuator (23) and a needle shield (22) to cover said needle. The cap further comprises a coupling between the actuator and the needle shield. The coupling is configured such that when the cap is attached to the body of an injection device axial movement of the actuator away from the body causes rotation of the needle shield relative to the body.
摘要翻译：本发明涉及一种用于注射装置（10）的帽（12）。注射装置包括用于保持注射器的主体，该注射器具有从其端部延伸的针。帽可拆卸地连接到身体上。帽包括致动器（23）和针罩（22）以覆盖所述针。帽进一步包括致动器和针护罩之间的联接。联接器被构造成使得当帽附接到注射装置的本体时，致动器远离本体的轴向运动引起针护罩相对于本体的旋转。

3. 发明申请

WO2017089262A1 AN INJECTION DEVICE 审中-公开
标题翻译：注射装置
公开(公告)号：WO2017089262A1
公开(公告)日：2017-06-01
申请号：PCT/EP2016/078251
申请日：2016-11-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： WENDLAND, Stefan , HARMS, Michael
IPC分类号： A61M5/32
CPC分类号： A61M5/3202 , A61M5/3204
摘要： The present invention relates to an injection device. The injection device comprises a cap and a body for holding a syringe that has a needle at one end. The cap is removably attached to the body and comprises a needle shield to cover said needle. The injection device further comprises a configuration adapted to increase the gas pressure at an interface of the injection device that is disposed between the body and a portion of the cap to urge the body and said portion of the cap apart.
摘要翻译：注射装置技术领域本发明涉及一种注射装置。注射装置包括帽和用于保持在一端具有针的注射器的主体。帽可拆卸地连接到身体并且包括针罩以覆盖所述针。注射装置还包括适于增加注射装置的界面处的气体压力的构造，所述注射装置设置在主体和帽的一部分之间以促使主体和帽的所述部分分开。

4. 发明申请

WO2017089255A1 AN AUTO-INJECTOR DEVICE 审中-公开
标题翻译：自动注射器装置
公开(公告)号：WO2017089255A1
公开(公告)日：2017-06-01
申请号：PCT/EP2016/078243
申请日：2016-11-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： WENDLAND, Stefan , HARMS, Michael
IPC分类号： A61M5/20
CPC分类号： A61M5/2033 , A61M5/20 , A61M2205/0266
摘要： An auto-injector device (100) comprises a medicament reservoir, a stopper (14) for expelling a medicament out of the medicament reservoir (18); a driving element (130), formed from a shape memory alloy, which has a first configuration and a second configuration and i configured to change shape from the first configuration to the second configuration when the temperature of the driving element is raised above a shape change temperature, so as to drive the stopper of the syringe mechanism through the medicament reservoir; and a heating mechanism configured to actively heat the driving element. The heating mechanism is a chemical heating element configured to generate heat through an exothermic process or comprises a fluid reservoir for retaining a fluid; a heater configured to heat the fluid in the fluid reservoir; a pump configured to expel the fluid out of the fluid reservoir; and a connecting conduit arranged to carry the fluid from the fluid reservoir to the driving element.
摘要翻译：自动注射器装置（100）包括药物储存器，用于将药剂从药物储存器（18）排出的塞子（14）; 驱动元件（130），其由形状记忆合金形成，其具有第一构造和第二构造，并且构造成当驱动元件的温度升高到形状变化以上时将形状从第一构造改变为第二构造以驱动注射器机构的塞子通过药剂储存器; 以及构造成主动加热驱动元件的加热机构。加热机构是配置成通过放热过程产生热量的化学加热元件，或者包括用于保持流体的流体储存器; 加热器，其构造成加热流体储存器中的流体; 泵，其构造成将流体排出流体储存器; 以及连接导管，该连接导管布置成将流体从流体储存器运送到驱动元件。

5. 发明申请

WO2017009360A1 DRUG DELIVERY DEVICE WITH PROTECTIVE NEEDLE CAP CONTROL AND DEVICE ACTIVATION MECHANISM 审中-公开
标题翻译：具有保护性针帽控制和装置激活机制的药物递送装置
公开(公告)号：WO2017009360A1
公开(公告)日：2017-01-19
申请号：PCT/EP2016/066585
申请日：2016-07-13
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： WENDLAND, Stefan , HARMS, Michael
IPC分类号： A61M5/32 , A61M5/162 , A61M5/31
CPC分类号： A61M5/3204 , A61M5/1626 , A61M5/3243 , A61M5/3257 , A61M2005/312 , A61M2005/3208 , A61M2005/3252
摘要： The invention relates to a drug delivery device (1) comprising - an outer body (3) adapted to receive a cartridge (4) with a needle (5), - a needle cap assembly (2) adapted to be coupled to the outer body (3) and to cover the needle (5) and - a control mechanism (7) for activating the drug delivery device (1), the control mechanism (7) comprises a control element (7.1) that is received within the outer body (3) and axially and/or rotationally movable relative to the outer body (3) between an initial position (P1), a first activating position (P2) and a second activating position (P3), - wherein the control element (7.1) is coupled to the needle cap assembly (2) and to the the cartridge (4), - wherein the needle cap assembly (2) is retained on the outer body (3) when the control element (7.1) is in the initial position (P1), - wherein the needle cap assembly (2) is released from the outer body (3) and the needle (5) is covered by the outer body (3) when the control element (7.1) is in the first activating position (P2), and - wherein the needle (5) is exposed when the control element (7.1) is in the second activating position (P3).
摘要翻译：本发明涉及一种药物输送装置（1），其包括：适于用针（5）容纳药筒（4）的外体（3）， - 针帽组件（2），适于联接到所述外体（3）并且覆盖针（5）和 - 用于启动药物输送装置（1）的控制机构（7），所述控制机构（7）包括容纳在外体内的控制元件（7.1） 3），并且在初始位置（P1），第一启动位置（P2）和第二启动位置（P3）之间相对于外主体（3）轴向和/或可旋转地移动，其中控制元件（7.1）其连接到所述针帽组件（2）和所述盒（4）上，其中当所述控制元件（7.1）处于初始位置时，所述针帽组件（2）保持在所述外主体（3）上），其中当所述控制元件（7.1）为t时，所述针帽组件（2）从所述外主体（3）释放并且所述针（5）被所述外主体（3）覆盖，第一启动位置（P2），和 - 当控制元件（7.1）处于第二启动位置（P3）时，针（5）暴露。

6. 发明申请

WO2014029679A1 CAP FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于药物递送装置和药物递送装置的CAP
公开(公告)号：WO2014029679A1
公开(公告)日：2014-02-27
申请号：PCT/EP2013/067056
申请日：2013-08-15
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： JUGL, Michael , HARMS, Michael
IPC分类号： A61M5/50
CPC分类号： A61M5/5086 , A61M2205/583
摘要： A cap (7) for a drug delivery device (1 ) is provided, the cap (7) comprising a main body (7A) and at least one indication element (1 1 ) which is moveably retained in the main body (7A), wherein the indication element (1 1 ) is configured to be moved from a first position to a second position with respect to the main body (7A), and wherein an information indicated to a user by the cap (7) is changed when the indication element (1 1 ) is moved from the first position into the second position. Furthermore, a drug delivery device (1 ) comprising the previously described cap (7) and an interaction member (13) is provided.
摘要翻译：提供了一种用于药物输送装置（1）的帽（7），帽（7）包括主体（7A）和可移动地保持在主体（7A）中的至少一个指示元件（11）其中，所述指示元件（11）被配置为相对于所述主体（7A）从第一位置移动到第二位置，并且其中当所述指示（11）指示给所述盖（7）的用户时，元件（11）从第一位置移动到第二位置。此外，提供了包括先前描述的帽（7）和相互作用构件（13）的药物递送装置（1）。

7. 发明申请

WO2013053781A1 ASSEMBLY FOR A DRUG DELIVERY DEVICE 审中-公开
标题翻译：组装药物递送装置
公开(公告)号：WO2013053781A1
公开(公告)日：2013-04-18
申请号：PCT/EP2012/070099
申请日：2012-10-11
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： HARMS, Michael
IPC分类号： A61M5/315
CPC分类号： A61M5/31585 , A61M5/31501 , A61M5/31543 , A61M5/31595
摘要： An assembly for a drug delivery device (1) is provided the assembly comprising a cartridge (2) adapted and arranged to contain at least one dose of a drug (7), a bung (10) being slidably arranged within the cartridge (2), a housing (3) comprising a distal end and a proximal end, and a piston rod (11) adapted and arranged for moving the bung (10) in the distal direction with respect to the housing (3) for dispensing a dose of the drug (7). The assembly further comprises a drive member (13) adapted and arranged for transferring movement to the piston rod (11) for dispensing the dose, and - an engagement member (18) configured to mechanically cooperate with the piston rod (11) and with the housing (3). The engagement member (18) is moveable between a reset position, where the engagement member (18) is allowed to rotate with respect to the housing (3), and an operating position, where the engagement member (18) is rotationally locked with respect to the housing (3), wherein the assembly is configured such that the engagement member (18) is rotated and simultaneously axially displaced during movement of the engagement member (18) between the operating position and the reset position. The engagement member (18) and the housing (3) are threadedly engaged with one another, wherein at least one of the engagement member (18) and the housing (3) comprises a thread and the other one of the engagement member (18) and the housing (3) comprises an interaction. Furthermore, the use of an engagement member (18) for a drug delivery device (1) is described.
摘要翻译：提供了一种用于药物输送装置（1）的组件，该组件包括适于并布置成容纳至少一个剂量的药物（7）的药筒（2），可滑动地布置在药筒（2）内的栓（10），包括远端和近端的壳体（3）和适于并布置成用于相对于所述壳体（3）沿所述远端方向移动所述栓（10）的活塞杆（11），用于分配一定量的药物（7）。组件还包括适于和布置用于将运动传递到活塞杆（11）以分配剂量的驱动构件（13），以及配置成与活塞杆（11）机械配合的接合构件（18）住房（3）。接合构件（18）能够在允许接合构件（18）相对于壳体（3）旋转的复位位置和操作位置之间移动，其中接合构件（18）相对于到所述壳体（3），其中所述组件被构造成使得所述接合构件（18）在所述接合构件（18）在所述操作位置和所述复位位置之间移动期间旋转并同时沿轴向移动。接合构件（18）和壳体（3）彼此螺纹接合，其中接合构件（18）和壳体（3）中的至少一个包括螺纹，并且接合构件（18）中的另一个构件并且所述壳体（3）包括相互作用。此外，描述了用于药物输送装置（1）的接合构件（18）的使用。

8. 发明申请

WO2010112565A1 DOSE BUTTON FOR A DRUG DELIVERY DEVICE AND METHOD FOR MANUFACTURING A DOSE BUTTON 审中-公开
标题翻译：用于药物递送装置的剂量按钮和用于制造剂量按钮的方法
公开(公告)号：WO2010112565A1
公开(公告)日：2010-10-07
申请号：PCT/EP2010/054352
申请日：2010-03-31
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , HARMS, Michael , RAAB, Steffen , STAUDER, Udo , AVERY, Richard, James, Vincent , LANGLEY, Christopher, Nigel , SENIOR, James, Alexander , DAVIES, James, Alexander
发明人： HARMS, Michael , RAAB, Steffen , STAUDER, Udo , AVERY, Richard, James, Vincent , LANGLEY, Christopher, Nigel , SENIOR, James, Alexander , DAVIES, James, Alexander
IPC分类号： A61M5/00 , A61M5/20
CPC分类号： A61M5/20 , A61M5/003 , A61M37/00 , A61M2205/582 , A61M2205/584 , A61M2205/6036 , A61M2205/6081 , Y10T82/10 , Y10T82/16016 , Y10T409/303752
摘要： The present invention relates to a drug delivery device (6) comprising a dose button (1). Furthermore it relates to a method for manufacturing a dose button (1) by using a cutting-off process. The aim of the present invention is to minimize the risk of using a drug delivery device (6) containing a wrong drug. By means of tactile features, a drug delivery device (6) is distinguishable from another drug delivery device (6) containing another type of drug. This tactile feature is manufactured by using a dose button (1) out of metal which is milled or lathed.
摘要翻译：本发明涉及包含剂量按钮（1）的药物输送装置（6）。此外，本发明涉及一种通过使用切断处理来制造剂量按钮（1）的方法。本发明的目的是最小化使用含有错误药物的药物递送装置（6）的风险。通过触觉特征，药物递送装置（6）可以与另一种类型的药物的另一种药物递送装置（6）区分开来。这种触觉特征是通过使用碾磨或车床的金属的剂量按钮（1）来制造的。

9. 发明申请

WO2009132778A1 MEDICATION DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置
公开(公告)号：WO2009132778A1
公开(公告)日：2009-11-05
申请号：PCT/EP2009/002808
申请日：2009-04-17
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , HARMS, Michael , HORWARTH, James, Robert, Stirling , COCKER, Robin, Craig , GREGORY, George, Richard , CHARPENTIER, Anthony, Raymond , STREHL, Michael , LEUSCHNER, Udo , BESENHARDT, Norbert
发明人： HARMS, Michael , HORWARTH, James, Robert, Stirling , COCKER, Robin, Craig , GREGORY, George, Richard , CHARPENTIER, Anthony, Raymond , STREHL, Michael , LEUSCHNER, Udo , BESENHARDT, Norbert
IPC分类号： A61M5/315
CPC分类号： A61M5/31541 , A61M5/24 , A61M5/3129 , A61M5/31543 , A61M5/31551 , A61M5/31561 , A61M5/31585 , A61M2005/2407 , A61M2005/2488 , A61M2005/3142 , A61M2205/581 , A61M2205/582 , A61M2205/585 , Y10T29/49826
摘要： The application refers to a medication delivery device (1) comprising: a medication receptacle (6), a dosing mechanism comprising: a piston rod (17) a drive device (19), a dose setting member (27) and a dose limiting member (28) which prevents the setting of a dose of medication which exceeds an amount of medication contained in the medication receptacle (6) and a housing (3). The dose limiting member (28) is designed for axial movement in a proximal direction with respect to the piston rod (17) during dose setting and comprises a first stop element (35) and the piston rod (17) comprises a second stop element (36). The first and second stop elements (35, 35) stop an axial movement of the dose limiting member (28) in the proximal direction with respect to the piston rod (17) when the first and second stop elements (35, 36) catch, thereby limiting a movement of the dose setting member (27) for increasing a set dose of medication to be delivered. The dose limiting member (28) and the piston rod (17) only interact directly, when the first and second stop elements (35, 36) catch.
摘要翻译：该应用是指药物输送装置（1），包括：药物容器（6），剂量机构，包括：活塞杆（17），驱动装置（19），剂量设定构件（27）和剂量限制构件（28），其防止超过药物容器（6）和壳体（3）中所含药物的量的药物剂量的设定。剂量限制构件（28）被设计用于在剂量设定期间相对于活塞杆（17）在近端方向上的轴向运动，并且包括第一止动元件（35），活塞杆（17）包括第二止动元件 36）。当第一和第二停止元件（35,36）捕获时，第一和第二止动元件（35,35）在相对于活塞杆（17）的近端方向上停止剂量限制元件（28）的轴向运动，从而限制剂量设定构件（27）的运动，用于增加待输送的药物的设定剂量。当第一和第二停止元件（35,36）捕获时，剂量限制构件（28）和活塞杆（17）仅直接相互作用。

10. 发明申请

WO2018202667A1 AUTO-INJECTOR STORAGE DEVICE 审中-公开
公开(公告)号：WO2018202667A1
公开(公告)日：2018-11-08
申请号：PCT/EP2018/061119
申请日：2018-05-02
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： WENDLAND, Stefan , HARMS, Michael
IPC分类号： A61M5/178 , B65D1/00 , A61M5/24 , A61M5/20 , A61M5/00 , A61M5/32 , A61B5/15 , A45C11/00 , H01R29/00
摘要： A storage device for storing a plurality of auto-injectors, the device configured to activate an auto-injector upon removal of the auto-injector from the device.

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