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1. 发明申请

US20060059083A1 User interface for semi-fungible trading 有权
公开(公告)号：US20060059083A1
公开(公告)日：2006-03-16
申请号：US11269057
申请日：2005-11-08
申请人： Richard Friesen , Mark Klizas
发明人： Richard Friesen , Mark Klizas
IPC分类号： G06Q40/00
CPC分类号： G06Q40/04 , G06Q20/10 , G06Q40/00 , G06Q40/06
摘要： A user interface and method are disclosed for providing trading between a plurality of semi-fungible and non-fungible goods. A plurality of book axes are displayed in a single interface, each book axis representing a market for a particular good. Orders for goods are displayed as marks on the axes to display the relative value of the orders. A value axis is provided that relates the value of the goods from each market to each other. Thus, a single interface provides the means to relate the values of different semi-fungible goods. The value axis may be displayed in units of price, or a custom value designated by a user or pre-defined by the interface. Quantity information is represented in the interface through the display of a dimension of an order icon. Precise information about each order is displayed either in a panel view or a pop-up window.

2. 发明申请

US20060259410A1 User interface for semi-fungible trading 有权
标题翻译：用于半互换交易的用户界面
公开(公告)号：US20060259410A1
公开(公告)日：2006-11-16
申请号：US11417881
申请日：2006-05-03
申请人： Richard Friesen , Mark Klizas
发明人： Richard Friesen , Mark Klizas
IPC分类号： G06Q40/00
CPC分类号： G06Q40/04 , G06Q20/10 , G06Q40/00 , G06Q40/06
摘要： A user interface and method are disclosed for providing trading between a plurality of semi-fungible and non-fungible goods. A plurality of book axes are displayed in a single interface, each book axis representing a market for a particular good Orders for goods are displayed as marks on the axes to display the relative value of the orders. A value axis is provided that relates the value of the goods from each market to each other. Thus, a single interface provides the means to relate the values of different semi-fungible goods. The value axis may be displayed in units of price, or a custom value designated by a user or pre-defined by the interface. Quantity information is represented in the interface through the display of a dimension of an order icon. Precise information about each order is displayed either in a panel view or a pop-up window.
摘要翻译：公开了用于提供多个半可替换和不可替代商品之间的交易的用户界面和方法。在单个界面中显示多个书籍轴，每个书籍轴表示特定商品的市场，商品订单在轴上显示为标记以显示订单的相对值。提供了一个价值轴，其将来自每个市场的货物的价值相互关联。因此，单一界面提供了将不同的半可替代商品的价值联系起来的手段。价值轴可以以价格或由用户指定或由界面预定义的自定义值来显示。数量信息通过显示订单图标的维度在界面中表示。关于每个订单的精确信息显示在面板视图或弹出窗口中。

3. 发明申请

US20060265315A1 User interface for semi-fungible trading 有权
公开(公告)号：US20060265315A1
公开(公告)日：2006-11-23
申请号：US11417515
申请日：2006-05-03
申请人： Richard Friesen , Mark Klizas
发明人： Richard Friesen , Mark Klizas
IPC分类号： G06Q40/00
CPC分类号： G06Q40/04 , G06Q20/10 , G06Q40/00 , G06Q40/06
摘要： A user interface and method are disclosed for providing trading between a plurality of semi-fungible and non-fungible goods. A plurality of book axes are displayed in a single interface, each book axis representing a market for a particular good. Orders for goods are displayed as marks on the axes to display the relative value of the orders. A value axis is provided that relates the value of the goods from each market to each other. Thus, a single interface provides the means to relate the values of different semi-fungible goods. The value axis may be displayed in units of price, or a custom value designated by a user or pre-defined by the interface. Quantity information is represented in the interface through the display of a dimension of an order icon. Precise information about each order is displayed either in a panel view or a pop-up window.

4. 发明申请

US20060259413A1 User interface for semi-fungible trading 有权
公开(公告)号：US20060259413A1
公开(公告)日：2006-11-16
申请号：US11418474
申请日：2006-05-03
申请人： Richard Friesen , Mark Klizas
发明人： Richard Friesen , Mark Klizas
IPC分类号： G06Q40/00 , G06F7/00 , G06F17/00
CPC分类号： G06Q40/04 , G06Q20/10 , G06Q40/00 , G06Q40/06
摘要： A user interface and method are disclosed for providing trading between a plurality of semi-fungible and non-fungible goods. A plurality of book axes are displayed in a single interface, each book axis representing a market for a particular good. Orders for goods are displayed as marks on the axes to display the relative value of the orders. A value axis is provided that relates the value of the goods from each market to each other. Thus, a single interface provides the means to relate the values of different semi-fungible goods. The value axis may be displayed in units of price, or a custom value designated by a user or pre-defined by the interface. Quantity information is represented in the interface through the display of a dimension of an order icon. Precise information about each order is displayed either in a panel view or a pop-up window.

5. 发明申请

US20090030048A1 Novel pharmaceutical compounds 审中-公开
标题翻译：新型药物化合物
公开(公告)号：US20090030048A1
公开(公告)日：2009-01-29
申请号：US12215499
申请日：2008-06-27
申请人： Marc Blouin , Erich L. Grimm , Yves Gareau , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Richard Friesen
发明人： Marc Blouin , Erich L. Grimm , Yves Gareau , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Richard Friesen
IPC分类号： A61K31/427 , A61K31/4245 , A61P11/06
CPC分类号： C07D417/14 , C07D413/12 , C07D417/12
摘要： The instant invention provides compounds of Formula Ia which are leukotriene biosynthesis inhibitors. Compounds of Formula Ia are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.
摘要翻译：本发明提供了作为白三烯生物合成抑制剂的式Ia化合物。式Ia的化合物可用作抗动脉粥样硬化，抗哮喘，抗过敏，抗炎和细胞保护剂。

6. 发明申请

US20050009875A1 Substituted pyridines as selective cyclooxygenase-2 inhibitors 失效
标题翻译：取代的吡啶作为选择性环氧合酶-2抑制剂
公开(公告)号：US20050009875A1
公开(公告)日：2005-01-13
申请号：US10916097
申请日：2004-08-11
申请人： Daniel Dube , Rejean Fortin , Richard Friesen , Zhaoyin Wang , Jacques Gauthier
发明人： Daniel Dube , Rejean Fortin , Richard Friesen , Zhaoyin Wang , Jacques Gauthier
IPC分类号： A61K31/44 , A61K31/444 , A61K31/655 , C07D213/04 , C07D213/22 , C07D213/26 , C07D213/34 , C07D213/36 , C07D213/44 , C07D213/54 , C07D213/61 , C07D213/65 , C07D213/75 , C07D213/80 , C07D213/85 , C07D213/89
CPC分类号： C07D213/75 , C07D213/34 , C07D213/61 , C07D213/65 , C07D213/80 , C07D213/85 , C07D213/89
摘要： The invention encompasses the novel compound of Formula I as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of Formula I.
摘要翻译：本发明包括式I的新化合物以及治疗COX-2介导的疾病的方法，包括向需要这种治疗无需治疗有效量的式I化合物的患者施用本发明还包括用于治疗包含式I化合物的COX-2介导的疾病的某些药物组合物。

7. 发明授权

US06204275B1 PDE IV inhibiting compounds, compositions and methods of treatment 失效
标题翻译： PDE IV抑制化合物，组合物和治疗方法
公开(公告)号：US06204275B1
公开(公告)日：2001-03-20
申请号：US09513149
申请日：2000-02-25
申请人： Richard Friesen , Yvbes Ducharme , Daniel Dube , Yves Girard , Richard Frenette , Chun Li , Marc Blouin , Nathalie Chauret , Laird Trimble
发明人： Richard Friesen , Yvbes Ducharme , Daniel Dube , Yves Girard , Richard Frenette , Chun Li , Marc Blouin , Nathalie Chauret , Laird Trimble
IPC分类号： C07D40102
CPC分类号： C07D213/30 , C07D213/89 , C07D417/14
摘要： The invention encompasses compounds of Formula I useful in the treatment of diseases, including asthma, by raising the level of cyclic adenosine-3′,5′-monophosphate (cAMP) through the inhibition of phosphodiesterase IV (PDE IV). The invention also encompasses certain pharmaceutical compositions and methods for treatment of diseases by inhibition of PDE IV, resulting in an elevation of cAMP, comprising the use of compounds of Formula I.
摘要翻译：本发明包括通过抑制磷酸二酯酶IV（PDE IV）提高环腺苷-3'，5'-单磷酸（cAMP）的水平，可用于治疗疾病（包括哮喘）的式I化合物。本发明还包括通过抑制PDE IV治疗疾病的某些药物组合物和方法，导致cAMP升高，包括使用式I化合物。

8. 发明授权

US5552437A Bisarylcarbinol derivatives as inhibitors of leukotriene biosynthesis 失效
标题翻译：二芳基甲醇衍生物作为白三烯生物合成的抑制剂
公开(公告)号：US5552437A
公开(公告)日：1996-09-03
申请号：US330036
申请日：1994-10-27
申请人： Daniel Delorme , Daniel Dub e , Yves Ducharme , Erich L. Grimm , Richard Friesen , Carole Lepine
发明人： Daniel Delorme , Daniel Dub e , Yves Ducharme , Erich L. Grimm , Richard Friesen , Carole Lepine
IPC分类号： A61K31/35 , A61K31/352 , A61K31/38 , A61K31/425 , A61K31/44 , A61K31/443 , A61K31/4433 , A61K31/47 , A61P25/04 , A61P29/00 , A61P43/00 , C07D277/22 , C07D311/16 , C07D405/04 , C07D405/12 , C07D405/14 , C07D407/04 , C07D409/04 , C07D417/04 , C07D417/10 , C07D417/12 , C07D417/14 , C07D521/00
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D311/16 , C07D405/04 , C07D405/12 , C07D405/14 , C07D407/04 , C07D409/04 , C07D417/04 , C07D417/12 , C07D417/14 , Y10S514/826
摘要： Compounds having the Formula I:R.sup.1 R.sup.2 C(OR.sup.3)--Ar.sup.1 --X--Ar.sup.2 --Ar.sup.3Ire inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
摘要翻译：具有式I的化合物：R1R2C（OR3）-Ar1-X-Ar2-Ar3I是白三烯生物合成的抑制剂。这些化合物可用作抗哮喘，抗过敏，抗炎和细胞保护剂。它们也可用于治疗心绞痛，脑痉挛，肾小球性肾炎，肝炎，内毒素血症，葡萄膜炎和同种异体移植物排斥和预防动脉粥样硬化斑块的形成。

9. 发明授权

US07960409B2 Pharmaceutical phenylquinoline and chromen-2-one triazole compounds 失效
标题翻译：药用苯基喹啉和色烯-2-酮三唑化合物
公开(公告)号：US07960409B2
公开(公告)日：2011-06-14
申请号：US12012246
申请日：2008-02-01
申请人： Erich L. Grimm , Yves Ducharme , Richard Frenette , Richard Friesen , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Yves Gareau
发明人： Erich L. Grimm , Yves Ducharme , Richard Frenette , Richard Friesen , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Yves Gareau
IPC分类号： A61K31/47 , A61K31/4192 , C07D487/04 , C07D401/06
CPC分类号： C07D401/06 , C07D401/14 , C07D405/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
摘要： The instant invention provides compounds of Formula I which are leukotriene biosynthesis inhibitors. Compounds of Formula I are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.
摘要翻译：本发明提供了作为白三烯生物合成抑制剂的式I化合物。式I的化合物可用作抗动脉粥样硬化，抗哮喘，抗过敏，抗炎和细胞保护剂。

10. 发明申请

US20070208017A1 2-(Phenyl or heterocyclic)-1H-phenantrho[9,10-d]imidazoles as mPGES-1 inhibitors 有权
标题翻译：作为mPGES-1抑制剂的2-（苯基或杂环）-1H-苯并[9,10-d]咪唑
公开(公告)号：US20070208017A1
公开(公告)日：2007-09-06
申请号：US11374288
申请日：2005-11-23
申请人： Anh Chau , Bernard Cote , Yves Ducharme , Richard Frenette , Richard Friesen , Marc Gagnon , Andre Giroux , Evelyn Martins , Hongping Yu , Tom Wu
发明人： Anh Chau , Bernard Cote , Yves Ducharme , Richard Frenette , Richard Friesen , Marc Gagnon , Andre Giroux , Evelyn Martins , Hongping Yu , Tom Wu
IPC分类号： A61K31/5377 , A61K31/4439 , A61K31/4245 , A61K31/4188 , C07D403/14 , C07D413/14
CPC分类号： C07D235/02 , C07D235/18 , C07D401/04 , C07D401/06 , C07D401/14 , C07D403/06 , C07D405/06 , C07D413/04 , C07D413/06
摘要： The invention encompasses novel compounds of Formula I or pharmaceutically acceptable salts thereof. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful to treat pain and/or inflammation from a variety of diseases or conditions, such as osteoarthritis, rheumatoid arthritis and acute or chronic pain. Methods of treating diseases or conditions mediated by the mPGES-1 enzyme and pharmaceutical compositions are also encompassed.
摘要翻译：本发明包括式I的新化合物或其药学上可接受的盐。这些化合物是微粒体前列腺素E合酶-1（mPGES-1）酶的抑制剂，因此可用于治疗各种疾病或病症如骨关节炎，类风湿性关节炎和急性或慢性疼痛的疼痛和/或炎症。还包括治疗由mPGES-1酶和药物组合物介导的疾病或病症的方法。

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