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1. 发明申请

WO2023002317A1 TREATMENT SYSTEM HAVING GENERATOR AND FLUID TRANSFER CARTRIDGE 审中-公开
公开(公告)号：WO2023002317A1
公开(公告)日：2023-01-26
申请号：PCT/IB2022/056519
申请日：2022-07-15
申请人： OTSUKA MEDICAL DEVICES CO., LTD.
发明人： MAZZONE, James D. , DAILEY, Eric , BEK, Robin , EASTERDAY, Kristen , HENDRICKS, Austin , GAMELSKY, Jeff , GUNASEKARAN, Venmathi , DONOVAN, Ryan R. , HILAMAN, Ryan J.
IPC分类号： A61F7/12 , A61B18/00 , A61B90/00 , A61N7/00
摘要： A treatment system (100) includes a generator (202) and a fluid transfer cartridge (204). The fluid transfer cartridge (204) includes a cartridge shell (306) defining a cartridge cavity (402) between a front face (402) and a rear face (404). The front face (402) includes an opening (406), and the cartridge cavity (402) is visibly exposed through the opening (406). The fluid transfer cartridge (204) includes a syringe barrel (408) disposed within the cartridge cavity (402), and a handle (307) that extends from the front face (404) over the opening (406). The syringe barrel (408) can be visibly exposed on a side (410) of the handle (307).

2. 发明申请

WO2023002332A1 METHODS AND SYSTEMS FOR DETERMINING BODY LUMEN SIZE 审中-公开
公开(公告)号：WO2023002332A1
公开(公告)日：2023-01-26
申请号：PCT/IB2022/056571
申请日：2022-07-18
申请人： OTSUKA MEDICAL DEVICES CO., LTD.
发明人： ZHAI, Liang , DAILEY, Eric , MAZZONE, James D. , BEK, Robin , BARMAN, Neil , THIRUMALAI, Shruthi
IPC分类号： A61B18/14 , A61B90/00 , A61N7/02 , A61B5/107
摘要： A tissue treatment system (100) configured to determine a size of a body lumen, or a neuromodulation parameter corresponding to the size of the body lumen, is described. The tissue treatment system (100) fills a balloon (112) with a fluid (213) when the balloon (112) is within a body lumen. A fluid parameter of the fluid (213) is detected over a period of time. A parameter curve (200¤) of the fluid parameter is determined. The parameter curve (2004) includes the fluid parameter versus an independent variable over the period of time. The parameter curve (2004) includes inflections (2006) that correspond to changes in the fluid parameter. Based on the inflections (2006), the system (100) can determine the body lumen size or the neuromodulation parameter.

3. 发明申请

WO2023002327A1 METHODS AND SYSTEMS FOR DETERMINING BODY LUMEN SIZE 审中-公开
公开(公告)号：WO2023002327A1
公开(公告)日：2023-01-26
申请号：PCT/IB2022/056563
申请日：2022-07-16
申请人： OTSUKA MEDICAL DEVICES CO., LTD.
发明人： ZHAI, Liang , DAILEY, Eric , MAZZONE, James D. , BEK, Robin , BARMAN, Neil , THIRUMALAI, Shruthi
IPC分类号： A61B18/14 , A61B90/00 , A61N7/02 , A61B5/107
摘要： A tissue treatment system and method of using the tissue treatment system determines a size of a body lumen, or a neuromodulation parameter corresponding to the size of the body lumen. The tissue treatment system fills a balloon with a fluid when the balloon is within a body lumen. A fluid parameter of the fluid is detected over a period of time. A parameter curve of the fluid parameter is determined. The parameter curve includes the fluid parameter versus an independent variable over the period of time. The system compares the parameter curve of the fluid parameter to a reference curve and, based on the comparison, determine the body lumen size or the neuromodulation parameter.

4. 发明申请

WO2023002352A1 TRANSMITTING ACOUSTIC AND ELECTROMAGNETIC SIGNALS FROM A CATHETER BALLOON 审中-公开
公开(公告)号：WO2023002352A1
公开(公告)日：2023-01-26
申请号：PCT/IB2022/056611
申请日：2022-07-19
申请人： OTSUKA MEDICAL DEVICES CO., LTD.
发明人： ZHAI, Liang , DAILEY, Eric , MAZZONE, James D. , CHEUNG, Desmond , THIRUMALAI, Shruthi
IPC分类号： A61N7/02
摘要： A catheter (10) has at least a first transducer (34) located in an interior of at least a first balloon (14), the first transducer (34) configured to be operated at an operational frequency. The first transducer (34) transmits an acoustic signal that provides a first acoustic field with multiple lobes along a longitudinal axis of the first transducer (34), each of the lobes has a spatial intensity maximum in a spatial intensity distribution of the first acoustic field, the spatial intensity distribution being at a surface of the first balloon (14) and parallel to a surface of the first transducer (34), the spatial intensity distribution of the first acoustic field having one or more reduced spatial acoustic intensity locations where the spatial intensity of the acoustic field of the first transducer (34) is 50% or less of a value of one of the spatial intensity maxima of the first transducer (34), each of the reduced spatial acoustic intensity locations being between the spatial intensity maxima for lobes that are adjacent to one another along the longitudinal axis of the first transducer (34), and each of the reduced spatial acoustic intensity locations being on the surface of the first balloon (14) between the spatial intensity maxima that are adjacent to one another along the longitudinal axis of the first transducer (34). The catheter (10) further comprises at least a first electrode (76) configured to transmit an electromagnetic signal, the first electrode (76) being positioned on the first balloon (14) at one of the reduced spatial acoustic intensity location of the first transducer (34).

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