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1. 发明授权

US06383764B1 Methods of identifying compounds for controlling absence seizures in a mammal relating to prolactin-releasing peptide(PrRP) 失效
标题翻译：识别用于控制哺乳动物中与催乳素释放肽（PrRP）有关的癫痫发作的化合物的方法
公开(公告)号：US06383764B1
公开(公告)日：2002-05-07
申请号：US09560915
申请日：2000-04-28
申请人： Olivier Civelli , Steven Lin
发明人： Olivier Civelli , Steven Lin
IPC分类号： G01N3353
CPC分类号： G01N33/74 , A61K31/00
摘要： The invention provides a substantially pure Prolactin Releasing Peptide (PrRP) functional analog which suppresses absence seizures in a mammal, and related pharmaceutical compositions. The invention also provides a method of controlling absence seizures in a mammal, by administering to a mammal susceptible to absence seizures an effective amount of PrRP or a PrRP functional analog. Also provided are methods of identifying a compound that modulates AMPA receptor signaling in a mammal, by providing a compound that is a PrRP or PrRP functional analog, and determining the ability of the compound to modulate AMPA receptor signaling. The invention also provides methods of identifying a compound for controlling absence seizures in a mammal, by providing a compound that is a PrRP or PrRP functional analog, and determining the ability of the compound to control absence seizures in a mammal. Also provided are pharmaceutical compositions for controlling absence seizures in a mammal. The compositions and related methods contain a compound identified by the methods of the invention as a compound that modulates AMPA receptor signaling or as a compound that controls absence seizures.
摘要翻译：本发明提供了基本上纯的催乳素释放肽（PrRP）功能类似物，其抑制哺乳动物的不存在发作，以及相关的药物组合物。本发明还提供了一种控制哺乳动物不存在癫痫发作的方法，该方法通过给予感染不发作的哺乳动物有效量的PrRP或PrRP功能性类似物。还提供了通过提供作为PrRP或PrRP功能类似物的化合物以及测定化合物调节AMPA受体信号传导的能力来鉴定调节哺乳动物AMPA受体信号传导的化合物的方法。本发明还提供了通过提供PrRP或PrRP功能类似物的化合物以及确定化合物控制哺乳动物中不存在癫痫发作的能力来鉴定用于控制哺乳动物中不存在发作的化合物的方法。还提供了用于控制哺乳动物中不存在癫痫发作的药物组合物。组合物和相关方法含有通过本发明的方法鉴定的化合物，其作为调节AMPA受体信号传导的化合物或作为控制不发作的化合物。

2. 发明授权

US06884596B2 Screening and therapeutic methods for promoting wakefulness and sleep 失效
标题翻译：用于促进觉醒和睡眠的筛查和治疗方法
公开(公告)号：US06884596B2
公开(公告)日：2005-04-26
申请号：US09932161
申请日：2001-08-17
申请人： Olivier Civelli , Steven Lin
发明人： Olivier Civelli , Steven Lin
IPC分类号： A61K31/00 , A61P5/02 , A61P5/04 , A61P25/08 , G01N33/74 , G01N33/53 , A61K38/00 , G01N33/566 , G01N33/567
CPC分类号： G01N33/74 , A61K31/00
摘要： The invention provides methods of screening for a compound for promoting wakefulness in a mammal. The method is practiced by providing a compound that is a PrRP receptor agonist and determining the ability of the compound to promote wakefulness. Also provided by the invention are methods of screening for a compound for promoting sleep in a mammal. The methods are practiced by providing a compound that is a PrRP receptor antagonist and determining the ability of the compound to promote sleep. In addition, the invention provides a method of promoting wakefulness in a mammal. The method is practiced by administering to a mammal an effective amount of a PrRP receptor agonist. The invention further provides a method of promoting sleep in a mammal. The method is practiced by administering to a mammal an effective amount of a PrRP receptor antagonist.
摘要翻译：本发明提供筛选用于促进哺乳动物觉醒的化合物的方法。该方法通过提供作为PrRP受体激动剂的化合物并确定化合物促进觉醒的能力来实施。本发明还提供筛选用于促进哺乳动物睡眠的化合物的方法。该方法通过提供作为PrRP受体拮抗剂的化合物并确定化合物促进睡眠的能力来实施。此外，本发明提供了一种促进哺乳动物的觉醒的方法。该方法通过向哺乳动物施用有效量的PrRP受体激动剂来实施。本发明还提供一种促进哺乳动物睡眠的方法。该方法通过向哺乳动物施用有效量的PrRP受体拮抗剂来实施。

3. 发明授权

US09533350B2 Device and method for powder distribution and additive manufacturing method using the same 有权
标题翻译：用于粉末分配的装置和方法及使用其的添加剂制造方法
公开(公告)号：US09533350B2
公开(公告)日：2017-01-03
申请号：US13460259
申请日：2012-04-30
申请人： Chuan-Sheng Zhuang , Ching-Chih Lin , Steven Lin , Wei-Lun Tai , Wen-Peng Tseng , Ji-Bin Horng
发明人： Chuan-Sheng Zhuang , Ching-Chih Lin , Steven Lin , Wei-Lun Tai , Wen-Peng Tseng , Ji-Bin Horng
IPC分类号： B22F1/00 , B29C67/00 , B22F3/105
CPC分类号： B05C19/005 , B05C19/008 , B05C19/06 , B22F1/0003 , B22F3/1055 , B22F2003/1056 , B23K26/342 , B23K26/702 , B29C64/153 , B29C64/20 , B33Y30/00 , B33Y40/00 , Y02P10/295
摘要： The present disclosure provides a device and method for powder distribution and an additive manufacturing method, wherein different size or kind of powders could be chosen to be accommodated within a receptacle. The receptacle can uniformly mix the powder by a rotation movement, pour out the powders by the rotation movement and distribute the powders for forming a layer by a translation movement. In another embodiment, the receptacle further comprises a heating element for preheating the powders. Not only can the present disclosure uniformly mix the powders so as to reduce the thermal deformation and distribute the powder layer compactly, but also can the present disclosure distribute different kinds of powder in different layer so as to increase the diversity in additive manufacturing.
摘要翻译：本公开内容提供了用于粉末分配的装置和方法以及添加剂制造方法，其中可以选择将不同尺寸或种类的粉末容纳在容器内。容器可以通过旋转运动均匀地混合粉末，通过旋转运动倾倒粉末，并通过平移运动分布用于形成层的粉末。在另一个实施例中，插座还包括用于预热粉末的加热元件。本发明不仅可以均匀地混合粉末，以减少热变形并且紧密地分布粉末层，而且本公开也可以在不同的层中分配不同种类的粉末，以增加添加剂制造的多样性。

4. 发明申请

US20130186514A1 Device and method for powder distribution and additive manufacturing method using the same 有权
标题翻译：用于粉末分配的装置和方法及使用其的添加剂制造方法
公开(公告)号：US20130186514A1
公开(公告)日：2013-07-25
申请号：US13460259
申请日：2012-04-30
申请人： Chuan-Sheng Zhuang , Ching-Chih Lin , Steven Lin , Wei-Lun Tai , Wen-Peng Tseng , Ji-Bin Horng
发明人： Chuan-Sheng Zhuang , Ching-Chih Lin , Steven Lin , Wei-Lun Tai , Wen-Peng Tseng , Ji-Bin Horng
IPC分类号： B65B1/04
CPC分类号： B05C19/005 , B05C19/008 , B05C19/06 , B22F1/0003 , B22F3/1055 , B22F2003/1056 , B23K26/342 , B23K26/702 , B29C64/153 , B29C64/20 , B33Y30/00 , B33Y40/00 , Y02P10/295
摘要： The present disclosure provides a device and method for powder distribution and an additive manufacturing method, wherein different size or kind of powders could be chosen to be accommodated within a receptacle. The receptacle can uniformly mix the powder by a rotation movement, pour out the powders by the rotation movement and distribute the powders for forming a layer by a translation movement. In another embodiment, the receptacle further comprises a heating element for preheating the powders. Not only can the present disclosure uniformly mix the powders so as to reduce the thermal deformation and distribute the powder layer compactly, but also can the present disclosure distribute different kinds of powder in different layer so as to increase the diversity in additive manufacturing.
摘要翻译：本公开内容提供了用于粉末分配的装置和方法以及添加剂制造方法，其中可以选择将不同尺寸或种类的粉末容纳在容器内。容器可以通过旋转运动均匀地混合粉末，通过旋转运动倾倒粉末，并通过平移运动分布用于形成层的粉末。在另一个实施例中，插座还包括用于预热粉末的加热元件。本发明不仅可以均匀地混合粉末，以减少热变形并且紧密地分布粉末层，而且本公开也可以在不同的层中分配不同种类的粉末，以增加添加剂制造的多样性。

5. 发明授权

US08014317B1 Next hop chaining for forwarding data in a network switching device 有权
标题翻译：下一跳链路用于在网络交换设备中转发数据
公开(公告)号：US08014317B1
公开(公告)日：2011-09-06
申请号：US12195686
申请日：2008-08-21
申请人： Kaushik Ghosh , Kireeti Kompella , Siva Gaggara , Nitin Kumar , Steven Lin
发明人： Kaushik Ghosh , Kireeti Kompella , Siva Gaggara , Nitin Kumar , Steven Lin
IPC分类号： H04L12/28 , H04L12/56 , G06F15/173
CPC分类号： H04L45/745 , H04L12/4633 , H04L45/02 , H04L45/50
摘要： A route for a data unit through a network may be defined based on a number of next hops. Exemplary embodiments described herein may implement a router forwarding table as a chained list of references to next hops. In one implementation, a device includes a forwarding table that includes: a first table configured to store, for each of a plurality of routes for data units in a network, a chain of links to next hops for the routes; and a second table configured to store the next hops. The device also includes a forwarding engine configured to assemble the next hops for the data units based on using the chain of links in the first table to retrieve the next hops in the second table and to forward the data units in the network based on the assembled next hops.
摘要翻译：可以基于下一跳的数量来定义通过网络的数据单元的路由。本文描述的示例性实施例可以将路由器转发表实现为对下一跳的链接列表。在一个实现中，设备包括转发表，其包括：第一表，被配置为针对网络中的数据单元的多条路由中的每一条存储到路由的下一跳的链路链路; 以及配置为存储下一跳的第二表。所述设备还包括转发引擎，所述转发引擎被配置为基于使用所述第一表中的链路链来组合所述数据单元的下一跳，以检索所述第二表中的下一跳，并且基于组合的所述网络转发所述网络中的数据单元下一跳

6. 发明授权

US07813346B1 Filter-based forwarding in a network 有权
标题翻译：网络中基于过滤器的转发
公开(公告)号：US07813346B1
公开(公告)日：2010-10-12
申请号：US09990204
申请日：2001-11-21
申请人： Ken Kuwabara , Steven Lin , Michael Langdon
发明人： Ken Kuwabara , Steven Lin , Michael Langdon
IPC分类号： H04L12/28
CPC分类号： H04L45/00 , H04L45/50 , H04L45/54 , H04L69/22
摘要： A router receives a packet at an ingress interface. The router classifies the received packet based on at least a first field value contained in the header of the packet. According to the classification of the received packet, the router associates one of the plurality of forwarding tables to the packet. The router then performs a lookup operation in the associated forwarding table according to at least a second field value contained in the header of the packet. Based on the lookup operation, the router determines an egress interface and transmits the received packet from the determined egress interface.
摘要翻译：路由器在入口接口接收数据包。所述路由器至少基于所述分组报头中包含的第一字段值对接收到的分组进行分类。根据接收到的分组的分类，路由器将多个转发表中的一个与该分组相关联。然后，路由器根据分组头部中的至少第二字段值在相关联的转发表中执行查找操作。基于查找操作，路由器确定出口接口并从确定的出口接口发送接收的分组。

7. 发明授权

US07675862B2 Networking hardware element to couple computer network elements and method of displaying a network layout map thereon 有权
标题翻译：用于耦合计算机网络元件的网络硬件元件以及在其上显示网络布局图的方法
公开(公告)号：US07675862B2
公开(公告)日：2010-03-09
申请号：US11506351
申请日：2006-08-17
申请人： Anthony Pham , Steven Lin , Jonathan Bettino , David Hoard
发明人： Anthony Pham , Steven Lin , Jonathan Bettino , David Hoard
IPC分类号： H04L12/26
CPC分类号： H04L41/22 , H04L41/12
摘要： In one embodiment, a networking hardware element (1100, 3100) capable of coupling computer network elements (1010) comprises a network diagnostic mechanism (2140) that is capable of mapping the computer network elements and that is also capable of determining a connection status for the computer network elements. The networking hardware element also comprises a display (2110, 3110, 5110) that is capable of communicating with the network diagnostic mechanism and that is also capable of displaying a network layout map (2111, 5111) of representations of the computer network elements and the connection status of the computer network elements.
摘要翻译：在一个实施例中，能够耦合计算机网络元件（1010）的联网硬件元件（1100,3100）包括网络诊断机构（2140），其能够映射计算机网络元件，并且还能够确定连接状态计算机网络元素。网络硬件元件还包括能够与网络诊断机构通信的显示器（2110,310,5110），并且还能够显示计算机网络元件的表示的网络布局图（2111,5111）和计算机网络元件的连接状态。

8. 发明申请

US20080067076A1 Method of reducing oxygen content in ECP solution 审中-公开
标题翻译：降低ECP溶液中氧含量的方法
公开(公告)号：US20080067076A1
公开(公告)日：2008-03-20
申请号：US11523135
申请日：2006-09-19
申请人： Ming-Yuan Cheng , Hsien-Ping Feng , Hsi-Kuei Cheng , Kei-Wei Chen , Jung-Chin Tsao , Steven Lin , Ray Chuang
发明人： Ming-Yuan Cheng , Hsien-Ping Feng , Hsi-Kuei Cheng , Kei-Wei Chen , Jung-Chin Tsao , Steven Lin , Ray Chuang
IPC分类号： C25D3/00
CPC分类号： C25D3/02 , C02F3/34
摘要： A novel method, which is suitable to substantially reduce the presence of oxygen micro-bubbles in an electroplating bath solution, is disclosed. The method includes the addition of aerobic bacteria to the electroplating bath solution to consume oxygen in the solution. Reduction of the oxygen content in the electroplating bath solution prevents oxygen micro-bubbles from forming in the solution and becoming trapped between the solution and the surface of a metal seed layer on a substrate to block the electroplating of a metal film onto the seed layer. Consequently, the presence of surface pits and other structural defects in the surface of the electroplated metal film is substantially reduced.
摘要翻译：公开了一种适合于显着减少电镀浴液中氧微气泡存在的新方法。该方法包括向电镀浴溶液中加入需氧细菌以消耗溶液中的氧气。电镀浴溶液中的氧含量的降低防止溶液中形成氧微气泡并被困在溶液与基底上的金属种子层的表面之间，以阻止金属膜在种子层上的电镀。因此，电镀金属膜的表面中存在表面凹坑等结构缺陷。

9. 发明申请

US20080043626A1 Networking hardware element to couple computer network elements and method of displaying a network layout map thereon 有权
标题翻译：用于耦合计算机网络元件的网络硬件元件以及在其上显示网络布局图的方法
公开(公告)号：US20080043626A1
公开(公告)日：2008-02-21
申请号：US11506351
申请日：2006-08-17
申请人： Anthony Pham , Steven Lin , Jonathan Bettino , David W. Hoard
发明人： Anthony Pham , Steven Lin , Jonathan Bettino , David W. Hoard
IPC分类号： H04L12/26
CPC分类号： H04L41/22 , H04L41/12
摘要： In one embodiment, a networking hardware element (1100, 3100) capable of coupling computer network elements (1010) comprises a network diagnostic mechanism (2140) that is capable of mapping the computer network elements and that is also capable of determining a connection status for the computer network elements. The networking hardware element also comprises a display (2110, 3110, 5110) that is capable of communicating with the network diagnostic mechanism and that is also capable of displaying a network layout map (2111, 5111) of representations of the computer network elements and the connection status of the computer network elements.
摘要翻译：在一个实施例中，能够耦合计算机网络元件（1010）的联网硬件元件（1100,3100）包括网络诊断机构（2140），其能够映射计算机网络元件，并且还能够确定连接状态计算机网络元素。网络硬件元件还包括能够与网络诊断机构通信的显示器（2110,310,5110），并且还能够显示计算机网络元件的表示的网络布局图（2111,5111）和计算机网络元件的连接状态。

10. 发明申请

US20080041570A1 ALTERNATING PLATE HEADERLESS HEAT EXCHANGERS 有权
标题翻译：替代板无头热交换器
公开(公告)号：US20080041570A1
公开(公告)日：2008-02-21
申请号：US11465207
申请日：2006-08-17
申请人： Kenneth Abels , W. Dennis Moss , Steven Lin , Alan Wu
发明人： Kenneth Abels , W. Dennis Moss , Steven Lin , Alan Wu
IPC分类号： F28F9/02
CPC分类号： F28F9/0221 , F28D1/0316 , F28F3/025
摘要： A plate and fin type heat exchanger has a heat exchanger core made from a plurality of stacked, alternating first and second heat exchange plates of a generally inverted, U-shaped cross-section. Each plate has a top wall, closed peripheral sidewalls and open ends, and the open ends of the first plates are oriented at 90° to the open ends of the second plates. The sidewalls of the plates have end portions, which in adjacent plates, are aligned to form corners of the heat exchanger core. Opposed U-shaped manifold bodies are provided having open ends and lateral walls joined in a fluid tight manner to the aligned plate sidewall end portions. End plates close off the open ends of the U-shaped bodies to form manifolds. The corners formed by the aligned plate sidewall end portions allow for an improved connection between the heat exchanger core and the U-shaped manifold bodies. This helps to ensure that a fluid tight seal is created between the heat exchanger core and the manifold bodies when the components are joined together.
摘要翻译：板翅式热交换器具有由大致倒U形横截面的多个层叠的，交替的第一和第二热交换板制成的热交换器芯。每个板具有顶壁，封闭的外围侧壁和开口端，并且第一板的开口端与第二板的开口端成90°取向。板的侧壁具有端部，其在相邻的板中对齐以形成热交换器芯的角部。提供了相对的U形歧管体，其具有以流体密封的方式连接到对齐的板侧壁端部的开口端和侧壁。端板封闭U形体的开口端形成歧管。由对准的板侧壁端部形成的角部允许在热交换器芯和U形歧管主体之间改善连接。这有助于确保当组件接合在一起时，在热交换器芯和歧管本体之间产生流体密封。

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