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1. 发明申请

US20110112012A1 Novel Protein for Binding Bacillus Thuringiensis Cry Toxins and Fragments of Cadherins for Enhancing Cry Toxicity Against Dipterans 审中-公开
标题翻译：用于结合苏云金芽孢杆菌的新型蛋白质用于增强对Dipterans的Cry毒性的卡介素的毒素和片段
公开(公告)号：US20110112012A1
公开(公告)日：2011-05-12
申请号：US12936027
申请日：2009-04-03
申请人： Michael J. Adang , Gang Hua , Mohd Amir Fursan Abdullah , Rui Zhang
发明人： Michael J. Adang , Gang Hua , Mohd Amir Fursan Abdullah , Rui Zhang
IPC分类号： A01N37/18 , A01P7/04 , C07K14/435 , A01H5/00
CPC分类号： A01N63/02 , C07K14/43563 , C07K14/705 , C12N15/8286 , Y02A40/162 , A01N2300/00
摘要： The subject invention relates in part to a novel protein for binding Bacillus thuringiensis Cry toxins, and fragments of cadherins for enhancing Cry toxicity against dipterans. The subject invention also relates in part to the discovery that fragments of a midgut cadherin from a dipteran insect synergize Cry proteins that are active against dipterans. Thus, the subject invention includes the use of fragments of cadherin ectodomains for controlling dipterans. Such fragments (that bind Crys) can be administered to a dipteran insect for ingestion. In some preferred embodiments, the source cadherin is a dipteran cadherin. Also in some preferred embodiments, the fragment is administered with a Cry protein that is active against a dipteran. Variants of the fragments of naturally occurring cadherins are included within the scope of the subject invention.
摘要翻译：本发明部分涉及用于结合苏云金芽孢杆菌Cry毒素的新型蛋白质和用于增强对dip子素的Cry毒性的钙粘蛋白片段。本发明还部分涉及这样一个发现，即来自二极虫昆虫的中肠钙粘蛋白的片段与对dip虫有活性的Cry蛋白协同作用。因此，本发明包括使用钙粘蛋白胞外域的片段来控制dip子。可以将这样的片段（结合Crys）施用于用于摄取的dip虫。在一些优选的实施方案中，源钙粘蛋白是二极体钙粘蛋白。同样在一些优选的实施方案中，所述片段与对dipteran有活性的Cry蛋白施用。天然存在的钙粘素的片段的变体包括在本发明的范围内。

2. 发明授权

US09215869B1 Non-cadherin polypeptide potentitators of cry proteins 有权
标题翻译：非钙粘蛋白多肽抑制蛋白的增效剂
公开(公告)号：US09215869B1
公开(公告)日：2015-12-22
申请号：US13090830
申请日：2011-04-20
申请人： Michael J. Adang , Rui Zhang , Gang Hua
发明人： Michael J. Adang , Rui Zhang , Gang Hua
IPC分类号： A01N37/18
CPC分类号： A01N37/18 , A01N63/02 , A01N37/46
摘要： The subject invention relates in part to fragments of non-cadherin Cry toxin binding proteins, wherein the fragments potentiate, or act as synergists with, the insecticidal activity of Cry proteins. In some preferred embodiments, the binding protein (a Cry protein receptor on insect midgut cells) is an aminopeptidase. In preferred embodiments, the fragment comprises a Cry protein binding region.
摘要翻译：本发明部分涉及非钙粘蛋白Cry毒素结合蛋白的片段，其中片段加强Cry蛋白的杀虫活性，或作为增效剂。在一些优选的实施方案中，结合蛋白（昆虫中肠细胞上的Cry蛋白受体）是氨基肽酶。在优选的实施方案中，片段包含Cry蛋白结合区。

3. 发明授权

US08101568B2 Peptides for inhibiting insects 有权
标题翻译：用于抑制昆虫的肽
公开(公告)号：US08101568B2
公开(公告)日：2012-01-24
申请号：US12163484
申请日：2008-06-27
申请人： Michael J. Adang , Gang Hua , Jian (John) Chen , Mohd Amir Fursan Abdullah
发明人： Michael J. Adang , Gang Hua , Jian (John) Chen , Mohd Amir Fursan Abdullah
IPC分类号： A01N37/18 , C12N15/82
CPC分类号： C12N15/8286 , A01N63/02 , C07K14/705 , Y02A40/162 , A01N2300/00
摘要： The subject invention pertains to the use of peptide fragments of cadherins (including cadherin-like proteins). The subject invention includes a cell (and use thereof) comprising a polynucleotide that expresses the peptide fragment. The subject invention includes methods of feeding the peptides to insects. In preferred embodiments, the peptides are fed to target insects together with one or more insecticidal proteins, preferably (but not limited to) B.t. Cry proteins. When used in this manner, the peptide fragment can not only enhance the apparent toxin activity of the Cry protein against the insect species that was the source of the receptor but also against other insect species. Preferably, the cadherin is a Bacillus thuringiensis (B.t.) insecticidal crystal protein (Cry) toxin receptor. Preferably, the peptide fragment is a binding domain of the receptor. In some preferred embodiments, the peptide is the binding domain nearest to the membrane proximal ectodomain. Corresponding domains are identifiable in a variety of B.t. toxin receptors.
摘要翻译：本发明涉及钙粘蛋白（包括钙粘蛋白样蛋白）的肽片段的用途。本发明包括含有表达肽片段的多核苷酸的细胞（及其用途）。本发明包括将肽喂入昆虫的方法。在优选的实施方案中，将肽与一种或多种杀虫蛋白一起进食至靶昆虫，优选（但不限于）B.t. 哭泣蛋白质当以这种方式使用时，肽片段不仅可以增强Cry蛋白对作为受体来源的昆虫物种的表观毒素活性，而且还可以抵抗其他昆虫物种。优选地，钙粘蛋白是苏云金芽孢杆菌（B.t.）杀虫晶体蛋白（Cry）毒素受体。优选地，肽片段是受体的结合结构域。在一些优选的实施方案中，肽是最接近膜近端胞外域的结合结构域。相应的域可以在各种B.t. 毒素受体。

4. 发明授权

US07396813B2 Method for inhibiting insects with an insect cadherin ectodomain 有权
标题翻译：用昆虫钙粘蛋白胞外域抑制昆虫的方法
公开(公告)号：US07396813B2
公开(公告)日：2008-07-08
申请号：US11040472
申请日：2005-01-21
申请人： Michael J. Adang , Gang Hua , Jiang Chen , Mohd Amir Fursan Abdullah
发明人： Michael J. Adang , Gang Hua , Jiang Chen , Mohd Amir Fursan Abdullah
IPC分类号： A01N37/18 , C12N15/82
CPC分类号： C12N15/8286 , A01N63/02 , C07K14/705 , Y02A40/162 , A01N2300/00
摘要： The subject invention pertains to the use of peptide fragments of cadherins (including cadherin-like proteins). The subject invention includes a cell (and use thereof) comprising a polynucleotide that expresses the peptide fragment. The subject invention includes methods of feeding the peptides to insects. In preferred embodiments, the peptides are fed to target insects together with one or more insecticidal proteins, preferably (but not limited to) B.t. Cry proteins. When used in this manner, the peptide fragment can not only enhance the apparent toxin activity of the Cry protein against the insect species that was the source of the receptor but also against other insect species. Preferably, the cadherin is a Bacillus thuringiensis (B.t.) insecticidal crystal protein (Cry) toxin receptor. Preferably, the peptide fragment is a binding domain of the receptor. In some preferred embodiments, the peptide is the binding domain nearest to the membrane proximal ectodomain. Corresponding domains are identifiable in a variety of B.t. toxin receptors.
摘要翻译：本发明涉及钙粘蛋白（包括钙粘蛋白样蛋白）的肽片段的用途。本发明包括含有表达肽片段的多核苷酸的细胞（及其用途）。本发明包括将肽喂入昆虫的方法。在优选的实施方案中，将肽与一种或多种杀虫蛋白一起进食至靶昆虫，优选（但不限于）B.t. 哭泣蛋白质当以这种方式使用时，肽片段不仅可以增强Cry蛋白对作为受体来源的昆虫物种的表观毒素活性，而且还可以抵抗其他昆虫物种。优选地，钙粘蛋白是苏云金芽孢杆菌（B.t.）杀虫晶体蛋白（Cry）毒素受体。优选地，肽片段是受体的结合结构域。在一些优选的实施方案中，肽是最接近膜近端胞外域的结合结构域。相应的域可以在各种B.t. 毒素受体。

5. 发明申请

US20090018075A1 Peptides in Inhibiting Insects 审中-公开
标题翻译：抑制昆虫的肽
公开(公告)号：US20090018075A1
公开(公告)日：2009-01-15
申请号：US12163508
申请日：2008-06-27
申请人： Michael J. Adang , Gang Hua , Jian (John) Chen , Mohd Amir Fursan Abdullah
发明人： Michael J. Adang , Gang Hua , Jian (John) Chen , Mohd Amir Fursan Abdullah
IPC分类号： A01N61/00 , C07K14/325 , A01P7/04
CPC分类号： C12N15/8286 , A01N63/02 , C07K14/705 , Y02A40/162 , A01N2300/00
摘要： The subject invention pertains to the use of peptide fragments of cadherins (including cadherin-like proteins). The subject invention includes a cell (and use thereof) comprising a polynucleotide that expresses the peptide fragment. The subject invention includes methods of feeding the peptides to insects. In preferred embodiments, the peptides are fed to target insects together with one or more insecticidal proteins, preferably (but not limited to) B.t. Cry proteins. When used in this manner, the peptide fragment can not only enhance the apparent toxin activity of the Cry protein against the insect species that was the source of the receptor but also against other insect species. Preferably, the cadherin is a Bacillus thuringiensis (B.t.) insecticidal crystal protein (Cry) toxin receptor. Preferably, the peptide fragment is a binding domain of the receptor. In some preferred embodiments, the peptide is the binding domain nearest to the membrane proximal ectodomain. Corresponding domains are identifiable in a variety of B.t. toxin receptors.
摘要翻译：本发明涉及钙粘蛋白（包括钙粘蛋白样蛋白）的肽片段的用途。本发明包括含有表达肽片段的多核苷酸的细胞（及其用途）。本发明包括将肽喂入昆虫的方法。在优选的实施方案中，将肽与一种或多种杀虫蛋白一起进食至靶昆虫，优选（但不限于）B.t. 哭泣蛋白质当以这种方式使用时，肽片段不仅可以增强Cry蛋白对作为受体来源的昆虫物种的表观毒素活性，而且还可以抵抗其他昆虫物种。优选地，钙粘蛋白是苏云金芽孢杆菌（B.t.）杀虫晶体蛋白（Cry）毒素受体。优选地，肽片段是受体的结合结构域。在一些优选的实施方案中，肽是最接近膜近端胞外域的结合结构域。相应的域可以在各种B.t. 毒素受体。

6. 发明申请

US20090018074A1 Peptides for Inhibiting Insects 有权
标题翻译：用于抑制昆虫的肽
公开(公告)号：US20090018074A1
公开(公告)日：2009-01-15
申请号：US12163484
申请日：2008-06-27
申请人： Michael J. Adang , Gang Hua , Jian (John) Chen , Mohd Amir Fursan Abdullah
发明人： Michael J. Adang , Gang Hua , Jian (John) Chen , Mohd Amir Fursan Abdullah
IPC分类号： A01N61/00 , C07K14/00 , A01P7/04
CPC分类号： C12N15/8286 , A01N63/02 , C07K14/705 , Y02A40/162 , A01N2300/00
摘要： The subject invention pertains to the use of peptide fragments of cadherins (including cadherin-like proteins). The subject invention includes a cell (and use thereof) comprising a polynucleotide that expresses the peptide fragment. The subject invention includes methods of feeding the peptides to insects. In preferred embodiments, the peptides are fed to target insects together with one or more insecticidal proteins, preferably (but not limited to) B.t. Cry proteins. When used in this manner, the peptide fragment can not only enhance the apparent toxin activity of the Cry protein against the insect species that was the source of the receptor but also against other insect species. Preferably, the cadherin is a Bacillus thuringiensis (B.t.) insecticidal crystal protein (Cry) toxin receptor. Preferably, the peptide fragment is a binding domain of the receptor. In some preferred embodiments, the peptide is the binding domain nearest to the membrane proximal ectodomain. Corresponding domains are identifiable in a variety of B.t. toxin receptors.
摘要翻译：本发明涉及钙粘蛋白（包括钙粘蛋白样蛋白）的肽片段的用途。本发明包括含有表达肽片段的多核苷酸的细胞（及其用途）。本发明包括将肽喂入昆虫的方法。在优选的实施方案中，将肽与一种或多种杀虫蛋白一起进食至靶昆虫，优选（但不限于）B.t. 哭泣蛋白质当以这种方式使用时，肽片段不仅可以增强Cry蛋白对作为受体来源的昆虫物种的表观毒素活性，而且还可以抵抗其他昆虫物种。优选地，钙粘蛋白是苏云金芽孢杆菌（B.t.）杀虫晶体蛋白（Cry）毒素受体。优选地，肽片段是受体的结合结构域。在一些优选的实施方案中，肽是最接近膜近端胞外域的结合结构域。相应的域可以在各种B.t. 毒素受体。

7. 发明授权

US08891861B2 Image classification 有权
标题翻译：图像分类
公开(公告)号：US08891861B2
公开(公告)日：2014-11-18
申请号：US13371719
申请日：2012-02-13
申请人： Gang Hua , Paul Viola
发明人： Gang Hua , Paul Viola
IPC分类号： G06K9/62 , G06F17/30 , G06K9/00 , G06K9/46
CPC分类号： G06F17/3025 , G06F17/30262 , G06K9/00664 , G06K9/4642 , G06K9/4652 , G06K9/6256 , G06K9/6285
摘要： Images are classified as photos (e.g., natural photographs) or graphics (e.g., cartoons, synthetically generated images), such that when searched (online) with a filter, an image database returns images corresponding to the filter criteria (e.g., either photos or graphics will be returned). A set of image statistics pertaining to various visual cues (e.g., color, texture, shape) are identified in classifying the images. These image statistics, combined with pre-tagged image metadata defining an image as either a graphic or a photo, may be used to train a boosting decision tree. The trained boosting decision tree may be used to classify additional images as graphics or photos based on image statistics determined for the additional images.
摘要翻译：图像被分类为照片（例如，自然照片）或图形（例如，漫画，综合生成的图像），使得当用过滤器搜索（在线）时，图像数据库返回与过滤标准相对应的图像（例如，照片或图形将被返回）。在对图像进行分类时，识别关于各种视觉提示（例如，颜色，纹理，形状）的一组图像统计信息。这些图像统计信息与将图像定义为图形或照片的预先标记的图像元数据可以用于训练增强决策树。经训练的增强决策树可以用于基于为附加图像确定的图像统计来将附加图像分类为图形或照片。

8. 发明授权

US08644563B2 Recognition of faces using prior behavior 有权
标题翻译：使用先前行为识别面部
公开(公告)号：US08644563B2
公开(公告)日：2014-02-04
申请号：US12637494
申请日：2009-12-14
申请人： Amir Akbarzadeh , Gang Hua
发明人： Amir Akbarzadeh , Gang Hua
IPC分类号： G06K9/00
CPC分类号： G06K9/00288 , G06K9/00677 , G06K9/6212
摘要： Face recognition may be performed using a combination of visual analysis and social context. In one example, a web site such as a social networking site or photo-sharing site allows users to upload photos, and allows faces that appear in the photo to be tagged with users' names. When user A uploads a new photo, two analyses may be performed. First, a face in the photo is compared with known faces of users to determine similarity. Second, it is determined which other users user A frequently uploads photos of. Two probability distributions are created. One distribution assigns high probabilities to users whose photos are similar to the new photo. The other assigns high probabilities to users who frequently appear in photos uploaded by user A. These probability distributions are combined, and the person in the photo is identified as being the person with the highest probability.
摘要翻译：可以使用视觉分析和社会语境的组合来执行面部识别。在一个示例中，诸如社交网站或照片共享网站的网站允许用户上传照片，并且允许照片中出现的脸部被用户的姓名标记。当用户A上传新照片时，可能会执行两次分析。首先，将照片中的脸部与用户的已知脸部进行比较，以确定相似性。其次，确定哪些其他用户A经常上传照片。创建两个概率分布。一个分配对于照片类似于新照片的用户分配高概率。另一方则将频繁出现在用户A上传的照片中的用户分配给高概率。这些概率分布相结合，照片中的人被识别为具有最高概率的人。

9. 发明申请

US20120159404A1 DETECTING VISUAL GESTURAL PATTERNS 审中-公开
标题翻译：检测视觉图案
公开(公告)号：US20120159404A1
公开(公告)日：2012-06-21
申请号：US13398645
申请日：2012-02-16
申请人： Srinath Vasireddy , Sergey Chub , Gang Hua , Ting-yi Yang
发明人： Srinath Vasireddy , Sergey Chub , Gang Hua , Ting-yi Yang
IPC分类号： G06F3/033
CPC分类号： H04N19/533 , G06T7/223 , G06T2207/10016 , H04N19/56
摘要： A processing device and method are provided for capturing images, via an image-capturing component of a processing device, and determining a motion of the processing device. An adaptive search center technique may be employed to determine a search center with respect to multiple equal-sized regions of an image frame, based on previously estimated motion vectors. One of several fast block matching methods may be used, based on one or more conditions, to match a block of pixels of one image frame with a second block of pixels of a second image. Upon matching blocks of pixels, motion vectors of the multiple equal-sized regions may be estimated. The motion may be determined, based on the estimated motion vectors, and an associated action may be performed. Various embodiments may implement techniques to distinguish motion blur from de-focus blur and to determine a change in lighting condition.
摘要翻译：提供了一种处理装置和方法，用于经由处理装置的图像捕获部件捕获图像，并且确定处理装置的运动。可以采用自适应搜索中心技术来基于先前估计的运动矢量来确定关于图像帧的多个等大小区域的搜索中心。可以使用几种快速块匹配方法中的一种，基于一个或多个条件来匹配一个图像帧的像素块与第二图像的第二像素块。在匹配像素块之后，可以估计多个等大小区域的运动矢量。可以基于估计的运动矢量来确定运动，并且可以执行相关联的动作。各种实施例可以实现将运动模糊与去焦点模糊区分开来并且确定照明条件的变化的技术。

10. 发明授权

US07936906B2 Face recognition using discriminatively trained orthogonal tensor projections 有权
标题翻译：使用区分训练正交张量投影的人脸识别
公开(公告)号：US07936906B2
公开(公告)日：2011-05-03
申请号：US11763909
申请日：2007-06-15
申请人： Gang Hua , Paul A Viola , Steven M. Drucker , Michael Revow
发明人： Gang Hua , Paul A Viola , Steven M. Drucker , Michael Revow
IPC分类号： G06K9/00
CPC分类号： G06K9/00288 , G06K9/6232
摘要： Systems and methods are described for face recognition using discriminatively trained orthogonal rank one tensor projections. In an exemplary system, images are treated as tensors, rather than as conventional vectors of pixels. During runtime, the system designs visual features—embodied as tensor projections—that minimize intraclass differences between instances of the same face while maximizing interclass differences between the face and faces of different people. Tensor projections are pursued sequentially over a training set of images and take the form of a rank one tensor, i.e., the outer product of a set of vectors. An exemplary technique ensures that the tensor projections are orthogonal to one another, thereby increasing ability to generalize and discriminate image features over conventional techniques. Orthogonality among tensor projections is maintained by iteratively solving an ortho-constrained eigenvalue problem in one dimension of a tensor while solving unconstrained eigenvalue problems in additional dimensions of the tensor.
摘要翻译：使用区分训练的正交秩一张量投影描述用于人脸识别的系统和方法。在示例性系统中，图像被视为张量，而不是像传统的像素矢量。在运行期间，系统设计视觉特征 - 体现为张量投影 - 最大限度地减少不同人脸部和脸部之间的类间差异，从而最大限度地减少同一脸部实例之间的差异。张量投影在训练图像集上顺序追溯，并采取一级张量的形式，即一组向量的外积。示例性技术确保张量投影彼此正交，从而增加了与常规技术相比的概括和区分图像特征的能力。通过迭代求解张量的一维中的邻域约束特征值问题，同时解决张量的附加维度中的无约束特征值问题，维持张量投影中的正交性。

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