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1. 发明授权

US08133217B2 Method and apparatus for marking a lumenal wall 有权
标题翻译：用于标记腔壁的方法和装置
公开(公告)号：US08133217B2
公开(公告)日：2012-03-13
申请号：US12113779
申请日：2008-05-01
申请人： Michael J. Stokes , Thomas E. Albrecht , James R. Giordano , Matthew D. Holcomb , Mark S. Ortiz , Mark S. Zeiner
发明人： Michael J. Stokes , Thomas E. Albrecht , James R. Giordano , Matthew D. Holcomb , Mark S. Ortiz , Mark S. Zeiner
IPC分类号： A61B18/18
CPC分类号： A61F5/0083 , A61B18/1492 , A61B2017/306 , A61B2018/00214 , A61B2018/0022 , A61B2018/00291 , A61B2018/00482 , A61B2018/00494 , A61B2090/3908 , A61B2090/395 , A61B2218/002 , A61B2218/007
摘要： A marking apparatus includes a selectively inflatable balloon. The balloon includes an external lumen adapted for connection to a vacuum source. The external lumen includes ports for creating a vacuum at the ports sufficient to draw walls of the gastric cavity into contact with the external lumen. The balloon is further provided with RF energy delivery devices. In accordance with an alternate embodiment, a marking apparatus includes an elongated, hollow body, the hollow body including a proximal end and a distal end. The hollow body includes at least one suction trough in which a plurality of holes is disposed to draw suction on tissue. The at least one suction trough extends along a substantial portion of the hollow body as it extends from its distal end to its proximal end.
摘要翻译：标记装置包括可选择性地充气的气球。气囊包括适于连接到真空源的外部内腔。外腔包括用于在足以将胃壁的壁与外腔接触的端口处产生真空的端口。气球还设有射频能量输送装置。根据替代实施例，标记装置包括细长的中空本体，中空本体包括近端和远端。所述中空体包括至少一个吸入槽，在所述至少一个吸入槽中设置有多个孔以在组织上抽吸。当所述至少一个吸入槽从其远端延伸到其近端时，所述至少一个吸入槽沿着所述中空体的主要部分延伸。

2. 发明授权

US08357156B2 Balloon tissue damage device 有权
标题翻译：气球组织损伤装置
公开(公告)号：US08357156B2
公开(公告)日：2013-01-22
申请号：US12113739
申请日：2008-05-01
申请人： Mark S. Ortiz , Thomas E. Albrecht , Mark S. Zeiner , James R. Giordano , Matthew D. Holcomb , Michael J. Stokes
发明人： Mark S. Ortiz , Thomas E. Albrecht , Mark S. Zeiner , James R. Giordano , Matthew D. Holcomb , Michael J. Stokes
IPC分类号： A61B18/18
CPC分类号： A61F5/0083 , A61B1/00165 , A61B18/1492 , A61B2017/306 , A61B2018/00214 , A61B2018/00291 , A61B2018/00494 , A61B2018/00898
摘要： An inflatable medical instrument for tissue damage in gastric reduction surgery includes a main chamber composed of a biocompatible material capable of being selectively inflated. The medical instrument also includes a longitudinally extending tab member secured to an outer surface of the main chamber, a series of suction holes are formed along the tab member and an electrode is mounted on the tab member. The present invention also provides a method for forming a tissue junction used in defining a gastric pouch including damaging opposed tissue layers, apposing the tissue layers and fastening the tissue layers to allow the tissue layers to heal together.
摘要翻译：用于胃减压手术中的组织损伤的充气医疗器械包括由能够选择性地膨胀的生物相容性材料构成的主室。医疗器械还包括固定到主室的外表面的纵向延伸的突片构件，沿着突片构件形成一系列吸孔，并且电极安装在突片构件上。本发明还提供了一种用于形成用于限定胃袋的组织连接的方法，包括有害的相对的组织层，放置组织层并紧固组织层以允许组织层一起愈合。

3. 发明申请

US20090275937A1 METHOD AND APPARATUS FOR MARKING A LUMENAL WALL 有权
标题翻译：方法和装置用于标记一个路面墙
公开(公告)号：US20090275937A1
公开(公告)日：2009-11-05
申请号：US12113779
申请日：2008-05-01
申请人： Michael J. Stokes , Thomas E. Albrecht , James R. Giordano , Matthew D. Holcomb , Mark S. Ortiz , Mark S. Zeiner
发明人： Michael J. Stokes , Thomas E. Albrecht , James R. Giordano , Matthew D. Holcomb , Mark S. Ortiz , Mark S. Zeiner
IPC分类号： A61B18/18
CPC分类号： A61F5/0083 , A61B18/1492 , A61B2017/306 , A61B2018/00214 , A61B2018/0022 , A61B2018/00291 , A61B2018/00482 , A61B2018/00494 , A61B2090/3908 , A61B2090/395 , A61B2218/002 , A61B2218/007
摘要： A marking apparatus includes a selectively inflatable balloon. The balloon includes an external lumen adapted for connection to a vacuum source. The external lumen includes ports for creating a vacuum at the ports sufficient to draw walls of the gastric cavity into contact with the external lumen. The balloon is further provided with RF energy delivery devices. In accordance with an alternate embodiment, a marking apparatus includes an elongated, hollow body, the hollow body including a proximal end and a distal end. The hollow body includes at least one suction trough in which a plurality of holes is disposed to draw suction on tissue. The at least one suction trough extends along a substantial portion of the hollow body as it extends from its distal end to its proximal end.
摘要翻译：标记装置包括可选择性地充气的气球。气囊包括适于连接到真空源的外部内腔。外腔包括用于在足以将胃壁的壁与外腔接触的端口处产生真空的端口。气球还设有射频能量输送装置。根据替代实施例，标记装置包括细长的中空本体，中空本体包括近端和远端。所述中空体包括至少一个吸入槽，在所述至少一个吸入槽中设置有多个孔以在组织上抽吸。当所述至少一个吸入槽从其远端延伸到其近端时，所述至少一个吸入槽沿着所述中空体的主要部分延伸。

4. 发明申请

US20090275942A1 BALLOON TISSUE DAMAGE DEVICE 有权
标题翻译：气球组织损伤装置
公开(公告)号：US20090275942A1
公开(公告)日：2009-11-05
申请号：US12113739
申请日：2008-05-01
申请人： Mark S. Ortiz , Thomas E. Albrecht , Mark S. Zeiner , James R. Giordano , Matthew D. Holcomb , Michael J. Stokes
发明人： Mark S. Ortiz , Thomas E. Albrecht , Mark S. Zeiner , James R. Giordano , Matthew D. Holcomb , Michael J. Stokes
IPC分类号： A61B18/18 , A61M29/00
CPC分类号： A61F5/0083 , A61B1/00165 , A61B18/1492 , A61B2017/306 , A61B2018/00214 , A61B2018/00291 , A61B2018/00494 , A61B2018/00898
摘要： An inflatable medical instrument for tissue damage in gastric reduction surgery includes a main chamber composed of a biocompatible material capable of being selectively inflated. The medical instrument also includes a longitudinally extending tab member secured to an outer surface of the main chamber, a series of suction holes are formed along the tab member and an electrode is mounted on the tab member. The present invention also provides a method for forming a tissue junction used in defining a gastric pouch including damaging opposed tissue layers, apposing the tissue layers and fastening the tissue layers to allow the tissue layers to heal together.
摘要翻译：用于胃减压手术中的组织损伤的充气医疗器械包括由能够选择性地膨胀的生物相容性材料构成的主室。医疗器械还包括固定到主室的外表面的纵向延伸的突片构件，沿着突片构件形成一系列吸孔，并且电极安装在突片构件上。本发明还提供了一种用于形成用于限定胃袋的组织连接的方法，包括有害的相对的组织层，放置组织层并紧固组织层以允许组织层一起愈合。

5. 发明申请

US20100023022A1 RELOADABLE LAPAROSCOPIC FASTENER DEPLOYING DEVICE WITH DISPOSABLE CARTRIDGE USE IN A GASTRIC VOLUME REDUCTION PROCEDURE 审中-公开
标题翻译：可释放的LAPAROSCOPIC紧固件配置可切换的药盒使用减少气体减少程序
公开(公告)号：US20100023022A1
公开(公告)日：2010-01-28
申请号：US12179604
申请日：2008-07-25
申请人： Mark S. Zeiner , Jason L. Harris , Michael J. Stokes , Matthew D. Holcomb , Mark S. Ortiz , Lawrence Crainich , Alex P. Kondor
发明人： Mark S. Zeiner , Jason L. Harris , Michael J. Stokes , Matthew D. Holcomb , Mark S. Ortiz , Lawrence Crainich , Alex P. Kondor
IPC分类号： A61B17/10
CPC分类号： A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0482 , A61B17/0493 , A61B17/3498 , A61B90/92 , A61B90/94 , A61B2017/003 , A61B2017/00477 , A61B2017/00526 , A61B2017/0053 , A61B2017/00818 , A61B2017/0409 , A61B2017/0417 , A61B2017/0464 , A61B2017/0475 , A61B2017/0477 , A61B2017/0496 , A61B2017/06052 , A61B2017/2916 , A61B2017/292 , A61B2017/2923 , A61B2050/3015
摘要： A cartridge containing a fastener. The cartridge has an elongated sheath containing at least one tissue penetrating member. The penetrating member at least partially houses a fastener. The fastener has at least two anchors connected together by a non-resilient flexible suture which does not resist deformation under compressible loads. The cartridge further includes a means for deploying the anchors, wherein the means is movable within the sheath.
摘要翻译：包含紧固件的墨盒。盒具有包含至少一个组织穿透构件的细长护套。穿透构件至少部分地容纳紧固件。紧固件具有至少两个通过非弹性柔性缝合线连接在一起的锚固件，其在可压缩载荷下不会抵抗变形。墨盒还包括用于展开锚固件的装置，其中该装置可在护套内移动。

6. 发明申请

US20110082471A1 Reloadable Laparoscopic Fastener Deploying Device 审中-公开
标题翻译：可重载腹腔镜紧固件部署装置
公开(公告)号：US20110082471A1
公开(公告)日：2011-04-07
申请号：US12573902
申请日：2009-10-06
申请人： Matthew D. Holcomb , Jason L. Harris , Michael J. Stokes , Mark S. Zeiner , Mark S. Ortiz , Alexander P. Kondor , Lawrence Crainich , Eugene L. Timperman
发明人： Matthew D. Holcomb , Jason L. Harris , Michael J. Stokes , Mark S. Zeiner , Mark S. Ortiz , Alexander P. Kondor , Lawrence Crainich , Eugene L. Timperman
IPC分类号： A61B17/10
CPC分类号： A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0482 , A61B17/3498 , A61B90/92 , A61B90/94 , A61B2017/00477 , A61B2017/00526 , A61B2017/0409 , A61B2017/0417 , A61B2017/0464 , A61B2017/0474 , A61B2017/0475 , A61B2017/0477 , A61B2017/0496 , A61B2017/06052 , A61B2017/2916 , A61B2017/2917 , A61B2017/292 , A61B2017/2923 , A61B2017/2926
摘要： A device for deploying fasteners including a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device has a first cartridge containing at least one fastener releasably connectable to the handle. The device also includes an elongated pusher movable through the hollow housing from the proximal to the distal end to deploy the fasteners. The device further includes a deforming member for deforming the pusher at a proximal end thereof while advancing the pusher to the distal end of the housing.
摘要翻译：一种用于展开紧固件的装置，包括手柄和至少一个致动器。手柄连接到具有远端和近端的细长的中空壳体。该装置具有容纳可释放地连接到手柄的至少一个紧固件的第一盒。该装置还包括细长的推动器，其可从近端到远端移动穿过中空壳体以展开紧固件。该装置还包括变形构件，用于使推动器在其近端处变形，同时将推动器推进到壳体的远端。

7. 发明授权

US09480590B2 Device for anchoring an endoluminal sleeve in the GI tract 有权
标题翻译：将腔内套管固定在胃肠道中的装置
公开(公告)号：US09480590B2
公开(公告)日：2016-11-01
申请号：US14239899
申请日：2012-08-23
申请人： Mark S. Ortiz , Mark S. Zeiner , Jason L. Harris , Matthew D. Holcomb , Michael J. Stokes
发明人： Mark S. Ortiz , Mark S. Zeiner , Jason L. Harris , Matthew D. Holcomb , Michael J. Stokes
IPC分类号： A61M5/00 , A61F5/00
CPC分类号： A61F5/0076 , A61F5/0089
摘要： Endoluminal sleeve device (1) for internally lining a section of the GI tract, comprising a sleeve (2) configured for deployment inside a GI tract, the sleeve (2) having walls of a flexible material defining a sleeve lumen (3), a proximal end (4) defining a proximal lumen opening (5), and a distal end (6) defining a distal lumen opening (7), a tubular anchoring portion (8) forming said proximal lumen end (4) and defining anchoring seats (9) delimited each one by an annular collar (11) forming an opening through which adjacent tissue portions (12) can be pulled into the anchoring seats (9), expansion means adapted to act on the tissue portions (12) arranged in the anchoring seats (9) such that the tissue portions (12) expand to a dimension greater than the opening of the annular collar (11).
摘要翻译：用于内部衬里胃肠道部分的内腔套管装置（1），包括构造成用于部署在胃肠道内的套筒（2），所述套管（2）具有限定套管内腔（3）的柔性材料的壁，限定近端腔开口（5）的近端（4）和限定远端内腔开口（7）的远端（6），形成所述近端内腔端部（4）的管状锚固部分（8） 9）通过形成开口的环形套环（11）限定，相邻组织部分（12）可以通过该开口被拉入锚固座（9），适于作用在布置在锚固中的组织部分（12）上的膨胀装置座（9），使得组织部分（12）膨胀成大于环形套环（11）的开口的尺寸。

8. 发明申请

US20140180192A1 Device for Anchoring an Endoluminal Sleeve in the GI Tract 有权
标题翻译：用于锚固胃肠道内管腔的装置
公开(公告)号：US20140180192A1
公开(公告)日：2014-06-26
申请号：US14239899
申请日：2012-08-23
申请人： Mark S. Ortiz , Mark S. Zeiner , Jason L. Harris , Matthew D. Holcomb , Michael J. Stokes
发明人： Mark S. Ortiz , Mark S. Zeiner , Jason L. Harris , Matthew D. Holcomb , Michael J. Stokes
IPC分类号： A61F5/00
CPC分类号： A61F5/0076 , A61F5/0089
摘要： Endoluminal sleeve device (1) for internally lining a section of the GI tract, comprising a sleeve (2) configured for deployment inside a GI tract, the sleeve (2) having walls of a flexible material defining a sleeve lumen (3), a proximal end (4) defining a proximal lumen opening (5), and a distal end (6) defining a distal lumen opening (7), a tubular anchoring portion (8) forming said proximal lumen end (4) and defining anchoring seats (9) delimited each one by an annular collar (11) forming an opening through which adjacent tissue portions (12) can be pulled into the anchoring seats (9), expansion means adapted to act on the tissue portions (12) arranged in the anchoring seats (9) such that the tissue portions (12) expand to a dimension greater than the opening of the annular collar (11).
摘要翻译：用于内部衬里胃肠道部分的内腔套管装置（1），包括构造成用于部署在胃肠道内的套筒（2），所述套管（2）具有限定套管内腔（3）的柔性材料的壁，限定近端腔开口（5）的近端（4）和限定远端内腔开口（7）的远端（6），形成所述近端内腔端部（4）的管状锚固部分（8） 9）通过形成开口的环形套环（11）限定，相邻组织部分（12）可以通过该开口被拉入锚固座（9），适于作用在布置在锚固中的组织部分（12）上的膨胀装置座（9），使得组织部分（12）膨胀成大于环形套环（11）的开口的尺寸。

9. 发明申请

US20100023024A1 RELOADABLE LAPAROSCOPIC FASTENER DEPLOYING DEVICE WITH DISPOSABLE CARTRIDGE FOR USE IN A GASTRIC VOLUME REDUCTION PROCEDURE 审中-公开
标题翻译：可放置的LAPAROSCOPIC紧固件，配有可拆卸的盒子用于减少气体减少程序
公开(公告)号：US20100023024A1
公开(公告)日：2010-01-28
申请号：US12179598
申请日：2008-07-25
申请人： Mark S. Zeiner , Jason L. Harris , Michael J. Stokes , Matthew D. Holcomb , Mark S. Ortiz , Lawrence Crainich , Alex P. Kondor
发明人： Mark S. Zeiner , Jason L. Harris , Michael J. Stokes , Matthew D. Holcomb , Mark S. Ortiz , Lawrence Crainich , Alex P. Kondor
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0482 , A61B17/0493 , A61B17/3498 , A61B90/92 , A61B90/94 , A61B2017/003 , A61B2017/00477 , A61B2017/00526 , A61B2017/0053 , A61B2017/00818 , A61B2017/0409 , A61B2017/0417 , A61B2017/0464 , A61B2017/0475 , A61B2017/0477 , A61B2017/0496 , A61B2017/06052 , A61B2017/2916 , A61B2017/292 , A61B2017/2923
摘要： A reloadable device for deploying fasteners. The device has a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device has a first cartridge containing at least one fastener releasably connectable to the handle. The fastener has at least two anchors connected together by a non-resilient flexible suture which does not resist deformation under compressible loads. The device also includes a means, adjacent the handle, for facilitating removal of the first cartridge from the handle and replacing it with a second cartridge.
摘要翻译：用于部署紧固件的可重装装置。该装置具有手柄和至少一个致动器。手柄连接到具有远端和近端的细长的中空壳体。该装置具有容纳可释放地连接到手柄的至少一个紧固件的第一盒。紧固件具有至少两个通过非弹性柔性缝合线连接在一起的锚固件，其在可压缩载荷下不会抵抗变形。该装置还包括与手柄相邻的装置，以便于将第一盒从手柄移除并用第二盒替换。

10. 发明申请

US20120080495A1 RELOADABLE LAPAROSCOPIC FASTENER DEPLOYING DEVICE 审中-公开
标题翻译：可靠的LAPAROSCOPIC紧固件分配装置
公开(公告)号：US20120080495A1
公开(公告)日：2012-04-05
申请号：US13325536
申请日：2011-12-14
申请人： Matthew D. Holcomb , Jason L. Harris , Michael J. Stokes , Mark S. Zeiner , Mark S. Ortiz , Alexander P. Kondor , Lawrence Crainich , Eugene L. Timperman
发明人： Matthew D. Holcomb , Jason L. Harris , Michael J. Stokes , Mark S. Zeiner , Mark S. Ortiz , Alexander P. Kondor , Lawrence Crainich , Eugene L. Timperman
IPC分类号： A61B17/068
CPC分类号： A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0482 , A61B17/3498 , A61B90/92 , A61B90/94 , A61B2017/00477 , A61B2017/00526 , A61B2017/0409 , A61B2017/0417 , A61B2017/0464 , A61B2017/0474 , A61B2017/0475 , A61B2017/0477 , A61B2017/0496 , A61B2017/06052 , A61B2017/2916 , A61B2017/2917 , A61B2017/292 , A61B2017/2923 , A61B2017/2926
摘要： A device for deploying fasteners including a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device has a first cartridge containing at least one fastener releasably connectable to the handle. The device also includes an elongated pusher movable through the hollow housing from the proximal to the distal end to deploy the fasteners. The device further includes a deforming member for deforming the pusher at a proximal end thereof while advancing the pusher to the distal end of the housing.
摘要翻译：一种用于展开紧固件的装置，包括手柄和至少一个致动器。手柄连接到具有远端和近端的细长的中空壳体。该装置具有容纳可释放地连接到手柄的至少一个紧固件的第一盒。该装置还包括细长的推动器，其可从近端到远端移动穿过中空壳体以展开紧固件。该装置还包括变形构件，用于使推动器在其近端处变形，同时将推动器推进到壳体的远端。

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