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1. 发明授权

US09375579B2 Preferred ADI/R: a permanent pacing mode to eliminate ventricular pacing while maintaining backup support 有权
公开(公告)号：US09375579B2
公开(公告)日：2016-06-28
申请号：US13154761
申请日：2011-06-07
申请人： David A. Casavant , Paul Belk , Thomas J. Mullen , John C. Stroebel
发明人： David A. Casavant , Paul Belk , Thomas J. Mullen , John C. Stroebel
IPC分类号： A61N1/372 , A61N1/368
CPC分类号： A61N1/368 , A61N1/3682 , A61N1/3688
摘要： A preferred atrial-based pacing method and apparatus is provided using an intelligent cardiac pacing system to having the ability to continue atrial-based pacing as long as relatively reliable AV conduction is present. In the event that such relatively reliable AV conduction is not present, mode switching to a DDD/R or a DDI/R pacing mode while continually biased to mode switch back to atrial-based pacing. The standard or relatively reliable AV conduction may be changed either automatically or manually. This increases pacing that utilizes natural AV conduction however possible so as to gain all the benefits of cardiac contractile properties resulting therefrom, while tolerating the occasional missed ventricular depolarization (i.e., non-conducted P-wave). In the event where relatively reliable AV conduction is not present, the pacing mode is switched to a DDD/R mode while detecting a return of the relatively reliable AV conduction (and resulting mode switch to preferred atrial based pacing).

2. 发明申请

US20110301656A1 PREFERRED ADI/R: A PERMANENT PACING MODE TO ELIMINATE VENTRICULAR PACING WHILE MAINTAINING BACKUP SUPPORT 有权
标题翻译：优先ADI / R：在维护备份支持时消除静态PAC的永久打开模式
公开(公告)号：US20110301656A1
公开(公告)日：2011-12-08
申请号：US13154761
申请日：2011-06-07
申请人： David A. Casavant , Paul Belk , Thomas J. Mullen , John C. Stroebel
发明人： David A. Casavant , Paul Belk , Thomas J. Mullen , John C. Stroebel
IPC分类号： A61N1/368 , A61N1/39
CPC分类号： A61N1/368 , A61N1/3682 , A61N1/3688
摘要： A preferred atrial-based pacing method and apparatus is provided using an intelligent cardiac pacing system to having the ability to continue atrial-based pacing as long as relatively reliable AV conduction is present. In the event that such relatively reliable AV conduction is not present, mode switching to a DDD/R or a DDI/R pacing mode while continually biased to mode switch back to atrial-based pacing. The standard or relatively reliable AV conduction may be changed either automatically or manually. This increases pacing that utilizes natural AV conduction however possible so as to gain all the benefits of cardiac contractile properties resulting therefrom, while tolerating the occasional missed ventricular depolarization (i.e., non-conducted P-wave). In the event where relatively reliable AV conduction is not present, the pacing mode is switched to a DDD/R mode while detecting a return of the relatively reliable AV conduction (and resulting mode switch to preferred atrial based pacing).
摘要翻译：只要存在相对可靠的AV传导，使用智能心脏起搏系统提供优选的基于心房的起搏方法和装置，以具有继续心房起搏的能力。在不存在这种相对可靠的AV传导的情况下，模式切换到DDD / R或DDI / R起搏模式，同时不断偏向模式切换回基于心房的起搏。标准或相对可靠的AV传导可以自动或手动改变。这增加了使用自然AV传导的起搏，尽可能地获得心脏收缩性质的所有益处，同时容忍偶尔的心室去极化（即，未传导的P波）。在不存在相对可靠的AV导通的情况下，起搏模式被切换到DDD / R模式，同时检测到相对可靠的AV导通的返回（并且导致的模式切换到优选的心房起搏）。

3. 发明授权

US07130683B2 Preferred ADI/R: a permanent pacing mode to eliminate ventricular pacing while maintaining back support 有权
标题翻译：优选的ADI / R：永久起搏模式，以消除心室起搏，同时保持支持
公开(公告)号：US07130683B2
公开(公告)日：2006-10-31
申请号：US10246816
申请日：2002-09-17
申请人： David A. Casavant , Paul Belk , Thomas J. Mullen , John C. Stroebel
发明人： David A. Casavant , Paul Belk , Thomas J. Mullen , John C. Stroebel
IPC分类号： A61N1/368
CPC分类号： A61N1/368 , A61N1/3682 , A61N1/3688
摘要： A preferred atrial-based pacing method and apparatus is provided using an intelligent cardiac pacing system to having the ability to continue atrial-based pacing as long as relatively reliable AV conduction is present. In the event that such relatively reliable AV conduction is not present, mode switching to a DDD/R or a DDI/R pacing mode while continually biased to mode switch back to atrial-based pacing. The standard or relatively reliable AV conduction may be changed either automatically or manually. This increases pacing that utilizes natural AV conduction whenever possible so as to gain all the benefits of cardiac contractile properties resulting therefrom, while tolerating the occasional missed ventricular depolarization (i.e., non-conducted P-wave). In the event where relatively reliable AV conduction is not present, the pacing mode is switched to a DDD/R mode while detecting a return of the relatively reliable AV conduction (and resulting mode switch to preferred atrial-based pacing).
摘要翻译：只要存在相对可靠的AV传导，使用智能心脏起搏系统提供优选的基于心房的起搏方法和装置，以具有继续心房起搏的能力。在不存在这种相对可靠的AV传导的情况下，模式切换到DDD / R或DDI / R起搏模式，同时不断偏向模式切换回基于心房的起搏。标准或相对可靠的AV传导可以自动或手动改变。这增加了使用天然AV传导的起搏，以便尽可能地获得由此产生的心脏收缩性质的所有益处，同时容忍偶尔的心室去极化（即，未传导的P波）。在不存在相对可靠的AV传导的情况下，起搏模式被切换到DDD / R模式，同时检测相对可靠的AV导通的返回（并且导致的模式切换到优选的基于心房的起搏）。

4. 发明授权

US07957800B2 Preferred ADI/R: a permanent pacing mode to eliminate ventricular pacing while maintaining backup support 有权
标题翻译：优选的ADI / R：一种永久起搏模式，可在维持备用支持的同时消除心室起搏
公开(公告)号：US07957800B2
公开(公告)日：2011-06-07
申请号：US11550035
申请日：2006-10-17
申请人： David A. Casavant , Paul Belk , Thomas J. Mullen , John C. Stroebel
发明人： David A. Casavant , Paul Belk , Thomas J. Mullen , John C. Stroebel
IPC分类号： A61N1/368
CPC分类号： A61N1/368 , A61N1/3682 , A61N1/3688
摘要： A preferred atrial-based pacing method and apparatus is provided using an intelligent cardiac pacing system to having the ability to continue atrial-based pacing as long as relatively reliable AV conduction is present. In the event that such relatively reliable AV conduction is not present, mode switching to a DDD/R or a DDI/R pacing mode while continually biased to mode switch back to atrial-based pacing. The standard or relatively reliable AV conduction may be changed either automatically or manually. This increases pacing that utilizes natural AV conduction however possible so as to gain all the benefits of cardiac contractile properties resulting therefrom, while tolerating the occasional missed ventricular depolarization (i.e., non-conducted P-wave). In the event where relatively reliable AV conduction is not present, the pacing mode is switched to a DDD/R mode while detecting a return of the relatively reliable AV conduction (and resulting mode switch to preferred atrial based pacing).
摘要翻译：只要存在相对可靠的AV传导，使用智能心脏起搏系统提供优选的基于心房的起搏方法和装置，以具有继续心房起搏的能力。在不存在这种相对可靠的AV传导的情况下，模式切换到DDD / R或DDI / R起搏模式，同时不断偏向模式切换回基于心房的起搏。标准或相对可靠的AV传导可以自动或手动改变。这增加了使用自然AV传导的起搏，尽可能地获得心脏收缩性质的所有益处，同时容忍偶尔的心室去极化（即，未传导的P波）。在不存在相对可靠的AV导通的情况下，起搏模式被切换到DDD / R模式，同时检测到相对可靠的AV导通的返回（并且导致的模式切换到优选的心房起搏）。

5. 发明授权

US07218965B2 Preferred ADI/R: a permanent pacing mode to eliminate ventricular pacing while maintaining backup support 有权
标题翻译：优选的ADI / R：一种永久起搏模式，可在维持备用支持的同时消除心室起搏
公开(公告)号：US07218965B2
公开(公告)日：2007-05-15
申请号：US10755454
申请日：2004-01-12
申请人： David Casavant , Paul Belk , Thomas J. Mullen , John C. Stroebel
发明人： David Casavant , Paul Belk , Thomas J. Mullen , John C. Stroebel
IPC分类号： A61N1/368
CPC分类号： A61N1/368 , A61N1/3682 , A61N1/3688
摘要： An ADI/R mode is implemented using an intelligent pacing system to continually monitor ventricular response. This ensures AV conduction whenever possible so as to gain all the benefits of cardiac contractile properties resulting from native R-waves. In the event where AV conduction is blocked, the pacing mode is switched to a DDD/R mode to ensure a paced R-wave. Thereafter, subsequent to a completed interval of a P-wave, ADI/R pacing resumes to monitor ventricular response.
摘要翻译：使用智能起搏系统实现ADI / R模式，以持续监测心室反应。这可以确保AV传导尽可能的，以便获得由天然R波引起的心脏收缩性能的所有好处。在AV导通被阻止的情况下，起搏模式切换到DDD / R模式以确保节奏R波。此后，在P波的完成间隔之后，恢复ADI / R起搏以监测心室反应。

6. 发明申请

US20070060963A1 PREFERRED ADI/R: A PERMANENT PACING MODE TO ELIMINATE VENTRICULAR PACING WHILE MAINTAINING BACKUP SUPPORT 有权
标题翻译：优先ADI / R：在维护备份支持时消除静态PAC的永久打开模式
公开(公告)号：US20070060963A1
公开(公告)日：2007-03-15
申请号：US11550035
申请日：2006-10-17
申请人： David Casavant , Paul Belk , Thomas Mullen , John Stroebel
发明人： David Casavant , Paul Belk , Thomas Mullen , John Stroebel
IPC分类号： A61N1/00
CPC分类号： A61N1/368 , A61N1/3682 , A61N1/3688
摘要： A preferred atrial-based pacing method and apparatus is provided using an intelligent cardiac pacing system to having the ability to continue atrial-based pacing as long as relatively reliable AV conduction is present. In the event that such relatively reliable AV conduction is not present, mode switching to a DDD/R or a DDI/R pacing mode while continually biased to mode switch back to atrial-based pacing. The standard or relatively reliable AV conduction may be changed either automatically or manually. This increases pacing that utilizes natural AV conduction however possible so as to gain all the benefits of cardiac contractile properties resulting therefrom, while tolerating the occasional missed ventricular depolarization (i.e., non-conducted P-wave). In the event where relatively reliable AV conduction is not present, the pacing mode is switched to a DDD/R mode while detecting a return of the relatively reliable AV conduction (and resulting mode switch to preferred atrial based pacing).
摘要翻译：只要存在相对可靠的AV传导，使用智能心脏起搏系统提供优选的基于心房的起搏方法和装置，以具有继续心房起搏的能力。在不存在这种相对可靠的AV传导的情况下，模式切换到DDD / R或DDI / R起搏模式，同时不断偏向模式切换回基于心房的起搏。标准或相对可靠的AV传导可以自动或手动改变。这增加了使用自然AV传导的起搏，尽可能地获得心脏收缩性质的所有益处，同时容忍偶尔的心室去极化（即，未传导的P波）。在不存在相对可靠的AV导通的情况下，起搏模式被切换到DDD / R模式，同时检测到相对可靠的AV导通的返回（并且导致的模式切换到优选的心房起搏）。

7. 发明申请

US20050137489A1 Method and apparatus for predicting arrhythmias using diurnal heart rate 有权
标题翻译：使用昼夜心率预测心律失常的方法和装置
公开(公告)号：US20050137489A1
公开(公告)日：2005-06-23
申请号：US11004176
申请日：2004-12-03
申请人： Troy Jackson , Paul Belk
发明人： Troy Jackson , Paul Belk
IPC分类号： A61B5/00 , A61B5/0215 , A61B5/024 , A61B5/0245 , A61B5/0402 , A61B5/0452 , A61B5/0464 , A61N1/362 , A61N1/365
CPC分类号： A61B5/7275 , A61B5/0031 , A61B5/0215 , A61B5/02405 , A61B5/02438 , A61B5/02455 , A61B5/0464 , A61N1/3622 , A61N1/365 , G06F19/00
摘要： A method of predicting an arrhythmia, such as ventricular tachycardia, for example, in a medical device using a quantitative measure in order to allow assessment of patient risk and to enable preventative interventions by the device and clinicians. The trending of day and night average heart rates, along with patient physical activity can be analyzed to provide prediction of impending arrhythmia within weeks. By examining day and night average heart rate for crossover points, where the night heart rate equals or exceeds the day rate, and monitoring for a concomitant elevation in the night heart rate from a reference value, specific days heralding an increased risk of arrhythmia can be determined and therapy can be updated accordingly
摘要翻译：一种预测心律失常（例如室性心动过速）的方法，例如在使用定量测量的医疗装置中，以便允许评估患者风险并使得设备和临床医师能够进行预防性干预。可以分析昼夜平均心率的趋势以及患者的身体活动，以便在几周内提供即将发生的心律失常的预测。通过检查夜间心率等于或超过日间率的交叉点的日夜平均心率，并从参考值监测夜间心率的伴随升高，预测心律失常风险增加的特定天数可以是确定和治疗可以相应更新

8. 发明申请

US20070060965A1 Preferred ADI/R: A Permanent Pacing Mode to Eliminate Ventricular Pacing While Maintaining Backup Support 审中-公开
标题翻译：首选ADI / R：永久起搏模式以消除心室起搏，同时维护备份支持
公开(公告)号：US20070060965A1
公开(公告)日：2007-03-15
申请号：US11554762
申请日：2006-10-31
申请人： David Casavant , Paul Belk , Thomas Mullen , John Stroebel
发明人： David Casavant , Paul Belk , Thomas Mullen , John Stroebel
IPC分类号： A61N1/362
CPC分类号： A61N1/368 , A61N1/3682 , A61N1/3688
摘要： An ADI/R mode is implemented using an intelligent pacing system to continually monitor ventricular response. This ensures AV conduction whenever possible so as to gain all the benefits of cardiac contractile properties resulting from native R-waves. In the event where AV conduction is blocked, the pacing mode is switched to a DDD/R mode to ensure a paced R-wave. Thereafter, subsequent to a completed interval of a p-wave, ADI/R pacing resumes to monitor ventricular response.
摘要翻译：使用智能起搏系统实现ADI / R模式，以持续监测心室反应。这可以确保AV传导尽可能的，以便获得由天然R波引起的心脏收缩性能的所有好处。在AV导通被阻止的情况下，起搏模式切换到DDD / R模式以确保节奏R波。此后，在p波的完成间隔之后，恢复ADI / R起搏以监测心室反应。

9. 发明申请

US20070060964A1 Preferred ADI/R: A Permanent Pacing Mode to Eliminate Ventricular Pacing While Maintaining Backup Support 有权
公开(公告)号：US20070060964A1
公开(公告)日：2007-03-15
申请号：US11554749
申请日：2006-10-31
申请人： David Casavant , Paul Belk , Thomas Mullen , John Stroebel
发明人： David Casavant , Paul Belk , Thomas Mullen , John Stroebel
IPC分类号： A61N1/00
CPC分类号： A61N1/368 , A61N1/3682 , A61N1/3688
摘要： An ADI/R mode is implemented using an intelligent pacing system to continually monitor ventricular response. This ensures AV conduction whenever possible so as to gain all the benefits of cardiac contractile properties resulting from native R-waves. In the event where AV conduction is blocked, the pacing mode is switched to a DDD/R mode to ensure a paced R-wave. Thereafter, subsequent to a completed interval of a p-wave, ADI/R pacing resumes to monitor ventricular response.

10. 发明授权

US07177683B2 History-dependent pacing interval determination for antitachycardia pacing 有权
标题翻译：历史依赖性起搏间隔测定用于抗心动过速起搏
公开(公告)号：US07177683B2
公开(公告)日：2007-02-13
申请号：US10426397
申请日：2003-04-30
申请人： Paul Belk
发明人： Paul Belk
IPC分类号： A61N1/365
CPC分类号： A61N1/3622
摘要： A method and device for delivering anti-tachycardia pacing pulses that may be used to treat episodes of atrial or ventricular tachycardia. Episodes of atrial or ventricular tachycardia can occur while the heart is at a normal rhythm or an accelerated rhythm. The method and device is directed to determining an estimate of action potential duration of a heart that experiences episodes of atrial or ventricular tachycardia for use in determining a pacing interval for anti-tachycardia pacing pulses that may more effectively terminate the tachycardia.
摘要翻译：用于递送可用于治疗心房或室性心动过速发作的抗心动过速起搏脉冲的方法和装置。心脏或心室心动过速的发作可能发生在心脏处于正常节律或加速节奏时。该方法和装置旨在确定经历心房或室性心动过速发作的心脏的动作电位持续时间的估计，以用于确定可以更有效地终止心动过速的抗心动过速起搏脉搏的起搏间隔。

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