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    • 7. 发明授权
    • N-substituted amino acid derivatives
    • N-取代氨基酸衍生物
    • US4054668A
    • 1977-10-18
    • US619125
    • 1975-10-02
    • Osamu KirinoTadashi OoishiNobuyuki KamedaToshiro KatoAkira FujinamiToshiaki Ozaki
    • Osamu KirinoTadashi OoishiNobuyuki KamedaToshiro KatoAkira FujinamiToshiaki Ozaki
    • A01N37/44C07C101/28A01N9/24A01N9/30C07C103/48
    • A01N37/44
    • Novel N-substituted amino acid derivatives of the formula: ##STR1## wherein R.sub.1 is an alkenyl group having 2 to 5 carbon atoms, a halogen-substituted alkenyl group having 2 to 5 carbon atoms or an alkynyl group having 2 to 5 carbon atoms, R.sub.2 is a methyl or ##STR2## group in which R.sub.2 ' is an alkyl group having 1 to 4 carbon atoms or a halogen-substituted alkyl group having 1 to 4 carbon atoms; and R.sub.3 is a hydrogen atom, an alkyl having 1 to 20 carbon atoms, cycloalkyl having 3 to 6 carbon atoms, benzyl, hydroxyethyl or methoxyethyl group, and inorganic or organic acid addition salts thereof, which possess useful soil fungicidal activities and can be produced by reacting a sarcosine derivative of the formula:CH.sub.3 HNCH.sub.2 COOR.sub.3 (II)wherein R.sub.3 is as defined above, with a halogen compound of the formula:R.sub.1 -- X (III)wherein R.sub.1 is as defined above and X is a halogen atom, or by reacting an N-substituted glycine derivative of the formula: ##STR3## wherein R.sub.1 and R.sub.3 are as defined above, with an acyl compound of the formula: ##STR4## wherein R.sub.2 ' is as defined above and X is a halogen atom.
    • 式(I)的新型N-取代氨基酸衍生物:其中R 1是具有2至5个碳原子的烯基,具有2至5个碳原子的卤素取代的烯基或具有2至5个炔基的新的N-取代的氨基酸衍生物 碳原子,R2是甲基或者基团,其中R2'是具有1至4个碳原子的烷基或具有1至4个碳原子的卤素取代的烷基; R3为氢原子,碳原子数1〜20的烷基,碳原子数为3〜6的环烷基,苄基,羟乙基或甲氧基乙基,以及无机或有机酸加成盐,具有有效的土壤杀真菌活性, 通过使下式的肌氨酸衍生物: