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1. 发明授权

US08900527B2 Pipetting device with independently movable pipette units 有权
标题翻译：移液器具有独立移动的移液器
公开(公告)号：US08900527B2
公开(公告)日：2014-12-02
申请号：US13169593
申请日：2011-06-27
申请人： Alessandro D'Amore , Urs Knecht , Rolf Schneebeli
发明人： Alessandro D'Amore , Urs Knecht , Rolf Schneebeli
IPC分类号： B01L3/00 , B01L3/02 , G01N35/10
CPC分类号： G01N35/1011 , B01L3/021 , G01N35/1016 , G01N35/1067
摘要： A pipetting device is described comprising more than one pipetting unit, wherein said pipetting units are independently movable in Y and Z direction and comprise at least one module arranged in a staggered manner compared to the adjacent pipetting unit.
摘要翻译：描述了包括多于一个移液单元的移液装置，其中所述移液单元可在Y和Z方向上独立地移动并且包括与相邻移液单元相比以交错方式布置的至少一个模块。

2. 发明申请

US20120186367A1 Pipetting Device with Independently Movable Pipette Units 有权
标题翻译：具有独立移动移液器单元的移液装置
公开(公告)号：US20120186367A1
公开(公告)日：2012-07-26
申请号：US13169593
申请日：2011-06-27
申请人： Alessandro D'Amore , Urs Knecht , Rolf Schneebeli
发明人： Alessandro D'Amore , Urs Knecht , Rolf Schneebeli
IPC分类号： B01L3/02
CPC分类号： G01N35/1011 , B01L3/021 , G01N35/1016 , G01N35/1067
摘要： A pipetting device is described comprising more than one pipetting unit, wherein said pipetting units are independently movable in Y and Z direction and comprise at least one module arranged in a staggered manner compared to the adjacent pipetting unit.
摘要翻译：描述了包括多于一个移液单元的移液装置，其中所述移液单元可在Y和Z方向上独立地移动并且包括与相邻移液单元相比以交错方式布置的至少一个模块。

3. 发明申请

US20150096356A1 Methods for Using A Pipetting Device with Independently Movable Pipette Units 审中-公开
标题翻译：使用独立移动移液器单元的移液装置的方法
公开(公告)号：US20150096356A1
公开(公告)日：2015-04-09
申请号：US14515668
申请日：2014-10-16
申请人： Alessandro D'Amore , Urs Knecht , Rolf Schneebeli
发明人： Alessandro D'Amore , Urs Knecht , Rolf Schneebeli
IPC分类号： B01L3/02 , G01N35/10
CPC分类号： G01N35/1011 , B01L3/021 , G01N35/1016 , G01N35/1067
摘要： A method of pipetting samples is described using a pipetting device comprising more than one pipetting unit, wherein said pipetting units are independently movable in Y and Z direction and comprise at least one module arranged in a staggered manner compared to the adjacent pipetting unit.
摘要翻译：使用包括多于一个移液单元的移液装置描述移液样品的方法，其中所述移液单元可独立地在Y和Z方向上移动并且包括与相邻移液单元相比以交错方式布置的至少一个模块。

4. 发明授权

US09244087B2 Methods for using a pipetting device with independently movable pipette units 有权
公开(公告)号：US09244087B2
公开(公告)日：2016-01-26
申请号：US14792155
申请日：2015-07-06
申请人： Alessandro D'Amore , Urs Knecht , Rolf Schneebeli
发明人： Alessandro D'Amore , Urs Knecht , Rolf Schneebeli
IPC分类号： B01L3/00 , B01L3/02 , G01N1/10 , G01N35/10
CPC分类号： G01N35/1011 , B01L3/021 , G01N35/1016 , G01N35/1067
摘要： The invention provides for a method of pipetting samples using a pipetting device including more than one pipetting unit. Each of the pipetting units are independently movable in Y and Z directions and includes an upper and a lower frame. Two adjacent pipetting units include a module arranged in a staggered manner in either of the respective upper and lower frames.

5. 发明申请

US20150309065A1 Methods for Using A Pipetting Device with Independently Movable Pipette Units 审中-公开
标题翻译：使用独立移动移液器单元的移液装置的方法
公开(公告)号：US20150309065A1
公开(公告)日：2015-10-29
申请号：US14792155
申请日：2015-07-06
申请人： Alessandro D'Amore , Urs Knecht , Rolf Schneebeli
发明人： Alessandro D'Amore , Urs Knecht , Rolf Schneebeli
IPC分类号： G01N35/10
CPC分类号： G01N35/1011 , B01L3/021 , G01N35/1016 , G01N35/1067
摘要： The invention provides for a method of pipetting samples using a pipetting device including more than one pipetting unit. Each of the pipetting units are independently movable in Y and Z directions and includes an upper and a lower frame. Two adjacent pipetting units include a module arranged in a staggered manner in either of the respective upper and lower frames.
摘要翻译：本发明提供了一种使用包括多于一个移液单元的移液装置吸取样品的方法。每个移液单元可独立地在Y和Z方向上移动，并且包括上框架和下框架。两个相邻的移液单元包括以相互交错的方式布置在相应的上框架和下框架中的任一个中的模块。

6. 发明授权

US09101922B2 Methods for using a pipetting device with independently movable pipette units 有权
标题翻译：使用具有独立移动移液管单元的移液装置的方法
公开(公告)号：US09101922B2
公开(公告)日：2015-08-11
申请号：US14515668
申请日：2014-10-16
申请人： Alessandro D'Amore , Urs Knecht , Rolf Schneebeli
发明人： Alessandro D'Amore , Urs Knecht , Rolf Schneebeli
IPC分类号： B01L3/00 , B01L3/02 , G01N1/10 , G01N35/10
CPC分类号： G01N35/1011 , B01L3/021 , G01N35/1016 , G01N35/1067
摘要： The invention provides for a method of pipetting samples using a pipetting device including more than one pipetting unit. Each of the pipetting units are independently movable in Y and Z directions and includes an upper and a lower frame. Two adjacent pipetting units include a module arranged in a staggered manner in either of the respective upper and lower frames.
摘要翻译：本发明提供了一种使用包括多于一个移液单元的移液装置吸取样品的方法。每个移液单元可独立地在Y和Z方向上移动，并且包括上框架和下框架。两个相邻的移液单元包括以相互交错的方式布置在相应的上框架和下框架中的任一个中的模块。

7. 发明申请

US20070017927A1 Containers and methods for the automated handling of a liquid 失效
标题翻译：用于自动处理液体的容器和方法
公开(公告)号：US20070017927A1
公开(公告)日：2007-01-25
申请号：US11481745
申请日：2006-07-05
申请人： Alessandro D'Amore , Siegfried Mueller
发明人： Alessandro D'Amore , Siegfried Mueller
IPC分类号： B65D25/10
CPC分类号： B01L3/50855 , B01L3/50825 , B01L3/50851 , B01L3/50853 , B29C45/1676 , B29L2031/712 , G01N35/0099 , G01N2035/0405
摘要： The invention relates to a method for the automated handling of a fluid biological sample in an analytical instrument. This method comprises providing on an analytical instrument a container having a cup portion held in a receptacle and having an opening as well as a cap portion comprising a cover closing said opening and being permanently attached to one side of said cup portion and a handling head. During automated operation, the handling head approaches said container to a side of said container having a closure by which said cover is vertically and reversibly fixed for closing said opening and horizontally asserts pressure on said closure to release said cover from said vertical and reversible fixation, and optionally raising said cover by raising said handling head to open said cup portion. Furthermore, the invention provides containers as well as instruments and systems suitable for the automated handling and processing of the fluid biological sample and discloses production methods for the manufacture of said vessels.
摘要翻译：本发明涉及一种在分析仪器中自动处理流体生物样品的方法。该方法包括在分析仪器上提供具有保持在容器中并具有开口的杯部分的容器以及包括封闭所述开口并永久地附接到所述杯部分的一侧的盖的盖部分和处理头。在自动操作期间，处理头接近所述容器到所述容器的具有封闭件的一侧，所述盖子垂直和可逆地固定以封闭所述开口，并水平地确定所述封闭件上的压力以将所述盖子从所述垂直和可逆的固定件释放，并且可选地通过抬高所述操作头来抬起所述盖以打开所述杯部。此外，本发明提供了适用于流体生物样品的自动处理和处理的容器以及仪器和系统，并且公开了用于制造所述容器的制造方法。

8. 发明授权

US08778281B2 Sample preparation dosing unit 失效
标题翻译：样品制备剂量单位
公开(公告)号：US08778281B2
公开(公告)日：2014-07-15
申请号：US12849840
申请日：2010-08-04
申请人： Tobias Holenstein , Thomas Engel , Thomas Sidler , Adelrich Zuppiger , Carsten Haack , Alessandro D'Amore , Michael Meyberg , Tobias Greuter , Roland Stoeckli
发明人： Tobias Holenstein , Thomas Engel , Thomas Sidler , Adelrich Zuppiger , Carsten Haack , Alessandro D'Amore , Michael Meyberg , Tobias Greuter , Roland Stoeckli
IPC分类号： B01L3/02 , G01N35/10 , G01N1/38
CPC分类号： G01N35/10 , G01N1/38 , G01N35/08 , G01N35/1002 , G01N35/1065 , Y10T137/0318 , Y10T137/85978
摘要： A sample preparation dosing unit for liquid dosing is provided comprising an inlet port and an outlet port fluidically coupling the sample preparation dosing unit to a supply and target, respectively; a pump, fluidically arranged between the inlet port and the outlet port; an outlet flow restrictor with an outlet flow resistance, fluidically arranged between a pump outlet and outlet port; and a control arrangement with a branch, a control valve, and a control flow restrictor with a control flow resistance. The branch divides the flow at the pump outlet into an outlet flow through the outlet flow restrictor and into a control flow through the control flow restrictor. The control flow downstream of the control flow restrictor is fed, depending on the state of the control valve, either into the outlet port thereby merging with the outlet flow downstream of the outlet flow restrictor, or into a bypass conduit.
摘要翻译：提供了用于液体计量的样品制备剂量单元，其包括分别将样品制备剂量单元流体耦合到供给和靶标的入口端口和出口端口; 泵，流体地布置在入口和出口之间; 具有出口流动阻力的出口限流器，其流体地布置在泵出口和出口之间; 以及具有分支，控制阀和具有控制流阻的控制流量限制器的控制装置。分支将泵出口处的流分成通过出口限流器的出口流，并通过控制流限流器进入控制流。控制流量限制器下游的控制流根据控制阀的状态进入出口，从而与出口限流器下游的出口流合并，或者进入旁路管道。

9. 发明授权

US07931879B2 Containers and methods for the automated handling of a liquid 失效
标题翻译：用于自动处理液体的容器和方法
公开(公告)号：US07931879B2
公开(公告)日：2011-04-26
申请号：US11481745
申请日：2006-07-05
申请人： Alessandro D'Amore , Siegfried Mueller
发明人： Alessandro D'Amore , Siegfried Mueller
IPC分类号： B01L3/00
CPC分类号： B01L3/50855 , B01L3/50825 , B01L3/50851 , B01L3/50853 , B29C45/1676 , B29L2031/712 , G01N35/0099 , G01N2035/0405
摘要： The invention relates to a method for the automated handling of a fluid biological sample in an analytical instrument. Furthermore, the invention provides containers as well as instruments and systems suitable for the automated handling and processing of the fluid biological sample and discloses production methods for the manufacture of the containers.
摘要翻译：本发明涉及一种在分析仪器中自动处理流体生物样品的方法。此外，本发明提供了适用于流体生物样品的自动处理和处理的容器以及仪器和系统，并且公开了用于制造容器的制造方法。

10. 发明申请

US20110030803A1 Sample Preparation Dosing Unit 失效
标题翻译：样品制备单位
公开(公告)号：US20110030803A1
公开(公告)日：2011-02-10
申请号：US12849840
申请日：2010-08-04
申请人： Tobias Holenstein , Thomas Engel , Thomas Sidler , Adelrich Zuppiger , Carsten Haack , Alessandro D'Amore , Michael Meyberg , Tobias Greuter , Roland Stoeckli
发明人： Tobias Holenstein , Thomas Engel , Thomas Sidler , Adelrich Zuppiger , Carsten Haack , Alessandro D'Amore , Michael Meyberg , Tobias Greuter , Roland Stoeckli
IPC分类号： F17D3/00
CPC分类号： G01N35/10 , G01N1/38 , G01N35/08 , G01N35/1002 , G01N35/1065 , Y10T137/0318 , Y10T137/85978
摘要： A sample preparation dosing unit for liquid dosing is provided comprising an inlet port and an outlet port fluidically coupling the sample preparation dosing unit to a supply and target, respectively; a pump, fluidically arranged between the inlet port and the outlet port; an outlet flow restrictor with an outlet flow resistance, fluidically arranged between a pump outlet and outlet port; and a control arrangement with a branch, a control valve, and a control flow restrictor with a control flow resistance. The branch divides the flow at the pump outlet into an outlet flow through the outlet flow restrictor and into a control flow through the control flow restrictor. The control flow downstream of the control flow restrictor is fed, depending on the state of the control valve, either into the outlet port thereby merging with the outlet flow downstream of the outlet flow restrictor, or into a bypass conduit.
摘要翻译：提供了用于液体计量的样品制备剂量单元，其包括分别将样品制备剂量单元流体耦合到供给和靶标的入口端口和出口端口; 泵，流体地布置在入口和出口之间; 具有出口流动阻力的出口限流器，其流体地布置在泵出口和出口之间; 以及具有分支，控制阀和具有控制流阻的控制流量限制器的控制装置。分支将泵出口处的流分成通过出口限流器的出口流，并通过控制流限流器进入控制流。控制流量限制器下游的控制流根据控制阀的状态进入出口，从而与出口限流器下游的出口流合并，或者进入旁路管道。

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