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1. 发明申请

WO2006010072A3 ELECTRONIC ANALYTE ASSAYING DEVICE 审中-公开
标题翻译：电子分析仪测试装置
公开(公告)号：WO2006010072A3
公开(公告)日：2006-09-08
申请号：PCT/US2005024422
申请日：2005-07-08
申请人： CHURCH & DWIGHT CO INC , NAZARETH ALBERT R , DELAHANTY FRANCIS T , BANDRU GREGORY M , WIECK HENRY J , SYNAKOWSKI STEPHEN R
发明人： NAZARETH ALBERT R , DELAHANTY FRANCIS T , BANDRU GREGORY M , WIECK HENRY J , SYNAKOWSKI STEPHEN R
IPC分类号： C12M3/00
CPC分类号： G01N33/5302 , G01N21/8483 , G01N33/54373 , G01N33/558 , G01N33/689
摘要： The invention is an electronically processed single-step test device for detecting the presence of a preselected analyte in a fluid. The device includes a hollow rectangular outer casing, disposed within co joined upper and lower sections of the casing are assay material, an electronic processing system, and a LCD display. The LCD display is observable through a viewing window. The assay material is a sorptive material including a fluid sample application region in the form of a sample wick in fluid communication with a test strip. The test strip includes an analyte capture region adjacent to a light shield. The electronic processing system includes red and green LEDs which are alternately pulsed or energized over predetermined periods of time to determine if fluid test results show a marker or markers in the capture region indicative of the presence of a preselected analyte in the fluid. If so, Yes+ is displayed on the LCD. If not, No- is displayed on the LCD.
摘要翻译：本发明是用于检测流体中预选分析物的存在的电子处理单步测试装置。该装置包括设置在壳体的共同连接的上部和下部中的中空矩形外壳，是测定材料，电子处理系统和LCD显示器。 LCD显示屏可通过观察窗观察。测定材料是吸附材料，其包括与测试条流体连通的样品芯形式的流体样品施加区域。测试条包括与光屏蔽相邻的分析物捕获区域。电子处理系统包括在预定时间段内交替脉冲或通电的红色和绿色LED，以确定流体测试结果是否显示捕获区域中的标记或指示流体中预选分析物存在的标记。如果是，则LCD显示Yes +。如果没有，则显示屏上不显示“No”。

2. 发明申请

WO2006010072A2 ELECTRONIC ANALYTE ASSAYING DEVICE 审中-公开
标题翻译：电子分析测试装置
公开(公告)号：WO2006010072A2
公开(公告)日：2006-01-26
申请号：PCT/US2005/024422
申请日：2005-07-08
申请人： CHURCH & DWIGHT CO., INC. , NAZARETH, Albert, R. , DELAHANTY, Francis, T. , BANDRU, Gregory, M. , WIECK, Henry, J. , SYNAKOWSKI, Stephen, R.
发明人： NAZARETH, Albert, R. , DELAHANTY, Francis, T. , BANDRU, Gregory, M. , WIECK, Henry, J. , SYNAKOWSKI, Stephen, R.
IPC分类号： C12M1/34
CPC分类号： G01N33/5302 , G01N21/8483 , G01N33/54373 , G01N33/558 , G01N33/689
摘要： The invention is an electronically processed single-step test device for detecting the presence of a preselected analyte in a fluid. The device includes a hollow rectangular outer casing, disposed within co joined upper and lower sections of the casing are assay material, an electronic processing system, and a LCD display. The LCD display is observable through a viewing window. The assay material is a sorptive material including a fluid sample application region in the form of a sample wick in fluid communication with a test strip. The test strip includes an analyte capture region adjacent to a light shield. The electronic processing system includes red and green LEDs which are alternately pulsed or energized over predetermined periods of time to determine if fluid test results show a marker or markers in the capture region indicative of the presence of a preselected analyte in the fluid. If so, Yes+ is displayed on the LCD. If not, No- is displayed on the LCD.
摘要翻译：本发明是用于检测流体中预选分析物的存在的电子处理的单步测试装置。该装置包括中空的矩形外壳，设置在外壳的共同连接的上部和下部内的是测定材料，电子处理系统和LCD显示器。 LCD显示屏可通过观察窗观察。测定材料是吸附材料，其包括呈与测试条流体连通的样品芯形式的流体样品施加区域。测试条包括与遮光罩相邻的分析物捕获区域。电子处理系统包括红色和绿色LED，其在预定的时间周期内交替地脉动或激励，以确定流体测试结果是否显示捕获区域中指示流体中存在预选分析物的一个或多个标记。如果是这样，LCD上会显示Yes +。如果没有，则LCD上显示No-。

3. 发明专利

CA2002848A1 WHOLLY MICROFABRICATED BIOSENSORS AND PROCESS FOR THE MANUFACTURE AND USE THEREOF 未知
公开(公告)号：CA2002848A1
公开(公告)日：1990-05-14
申请号：CA2002848
申请日：1989-11-14
申请人： COZZETTE STEPHEN N , ITAK JEANNE A , MIER RANDALL M , SMIT NICOLAAS , WERF PAUL V D , DAVIS GRAHAM , LAUKS IMANTS R , PIZNIK SYLVIA , STEINER SUSAN J , WIECK HENRY J
发明人： COZZETTE STEPHEN N , ITAK JEANNE A , MIER RANDALL M , SMIT NICOLAAS , VAN DER WERF PAUL , DAVIS GRAHAM , LAUKS IMANTS R , PIZNIK SYLVIA , STEINER SUSAN J , WIECK HENRY J
IPC分类号： H04R1/44 , B01D20060101 , B01L3/00 , B01L3/02 , B67D20060101 , C12Q20060101 , C12Q1/00 , G01N20060101 , G01N1/28 , G01N27/07 , G01N27/26 , G01N27/327 , G01N27/333 , G01N27/414 , G01N27/416 , G01N33/543 , G01N35/00 , G01N35/10 , G01V9/00 , G10K11/00 , H04R20060101 , H04R1/02 , H04R15/00 , C12M1/40 , C12N11/00 , C07K17/02 , C12Q1/68
摘要： An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional features of the various components and layers established on a suitable substrate. Such control extends to those parts of the devices which incorporate the biological components which enable these devices to function as biological sensors. The materials and methods disclosed herein thus provide an effective means for the mass production of uniform wholly microfabricated biosensors. Various embodiments of the devices themselves are described herein which are especially suited for real time analyses of biological samples in a clinical setting. In particular, the present invention describes assays which can be performed using certain ligand/ligand receptor-based biosensor embodiments. The present invention also discloses a novel method for the electrochemical detection of particular analyte species of biological and physiological significance using an substrate/label signal generating pair which produces a change in the concentration of electroactive species selected from the group consisting of dioxygen and hydrogen peroxide.

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