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1. 发明申请

US20130150961A1 METHOD OF IMPLANTING AN INTRAOCULAR LENS 审中-公开
标题翻译：植入眼内镜的方法
公开(公告)号：US20130150961A1
公开(公告)日：2013-06-13
申请号：US13760782
申请日：2013-02-06
申请人： Visiogen, Inc.
发明人： Scott Evans , Reza Zadno , Luis Vargas
IPC分类号： A61F2/16
CPC分类号： A61F2/1627 , A61F2/1601 , A61F2/1613 , A61F2/1629 , A61F2/1648 , B29D11/023
摘要： A method is provided for implanting an accommodating intraocular lens system in a capsular bag of an eye. The method includes providing the accommodating intraocular lens having an anterior viewing element and a posterior viewing element. The anterior viewing element has a width in a range between approximately 4.5 millimeters and approximately 6.5 millimeters. The method further includes forming an opening in an anterior portion of the capsular bag. The opening has a minimum width not less than approximately 4 millimeters and has a maximum width not greater than approximately 6.0 millimeters. The method further includes placing the accommodating intraocular lens system within the capsular bag. The capsular bag overlaps at least a portion of the anterior viewing element and defines an overlap region with a width in a range between approximately 0.1 millimeters and approximately 0.75 millimeters.
摘要翻译：提供了一种用于将适应性眼内透镜系统植入眼袋的方法。该方法包括提供具有前观察元件和后观察元件的适应性眼内透镜。前视观察元件的宽度在约4.5毫米至约6.5毫米之间的范围内。该方法还包括在囊袋的前部形成开口。开口具有不小于约4毫米的最小宽度，并且具有不大于约6.0毫米的最大宽度。该方法还包括将容纳的眼内透镜系统放置在囊袋内。囊袋与前观察元件的至少一部分重叠并且限定了宽度在约0.1毫米至约0.75毫米之间的范围内的重叠区域。

2. 发明授权

US08680172B2 Copolymers for intraocular lens systems 有权
标题翻译：眼内透镜系统共聚物
公开(公告)号：US08680172B2
公开(公告)日：2014-03-25
申请号：US13868727
申请日：2013-04-23
申请人： Visiogen, Inc.
发明人： Xiugao Liao
IPC分类号： A61F2/16 , C08F290/06
CPC分类号： A61F2/16 , A61F2/1648 , A61F2002/1681 , C08F220/18 , C08F220/36 , C08F230/08
摘要： Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.
摘要翻译：一些实施方案提供了一种共聚物，其包含：丙烯酸酯重复单元和任选取代的乙烯基芳基重复单元，其中至少一个重复单元的一部分包含乙烯基二烷基甲硅烷氧基侧基。共聚物可用作眼内透镜的柔软的丙烯酸类触觉剂。一些实施例进一步涉及具有疏水性柔性丙烯酸光学元件和硅树脂触觉元件的眼内透镜，例如具有疏水柔软的丙烯酸前和后视觉体和硅树脂触觉的双光学调节透镜。相关的共聚合复合材料以及眼内透镜的另外的实施方案也在本文中描述。

3. 发明申请

US20130304077A1 METHOD AND DEVICE FOR INSERTING AN INTRAOCULAR LENS 有权
标题翻译：插入眼科镜片的方法和装置
公开(公告)号：US20130304077A1
公开(公告)日：2013-11-14
申请号：US13865019
申请日：2013-04-17
申请人： Visiogen, Inc.
发明人： George Tsai , Tuan Anh Nguyen , Phu H. Nguyen , Scott Evans
IPC分类号： A61F2/16
CPC分类号： A61F2/1675 , A61F2/1629 , A61F2/1648 , A61F2/1678 , A61F2002/1683 , A61F2250/0021 , A61F2250/0025
摘要： An injector for inserting an intraocular lens into an eye includes a lumen. The lumen can include a terminal portion at a distal end and a proximal portion juxtaposed with the terminal portion. An injector plunger can be disposed within the lumen for generating a driving force on the intraocular lens. The injector can include a lens frictional force that has a first value when the lens is at a first location within the proximal portion and a second value when the lens is at a second location within the terminal portion. The first value can be smaller than the second value. In some embodiments, the lens frictional force increases abruptly from the first value to the second value as the lens approaches the distal end of the lumen.
摘要翻译：用于将眼内透镜插入眼睛的注射器包括管腔。内腔可包括位于远端的末端部分和与终端部分并置的近端部分。注射器柱塞可以设置在内腔内，以在眼内透镜上产生驱动力。注射器可以包括当透镜位于近端部分内的第一位置时具有第一值的透镜摩擦力，以及当透镜位于端子部分内的第二位置时的第二值。第一个值可以小于第二个值。在一些实施例中，当镜片接近管腔的远端时，透镜摩擦力从第一值突然增加到第二值。

4. 发明授权

US08784485B2 Method and device for inserting an intraocular lens 有权
标题翻译：用于插入眼内透镜的方法和装置
公开(公告)号：US08784485B2
公开(公告)日：2014-07-22
申请号：US13865019
申请日：2013-04-17
申请人： Visiogen, Inc.
发明人： George Tsai , Tuan Anh Nguyen , Phu Nguyen , Scott Evans
IPC分类号： A61F2/16 , A61F9/00
CPC分类号： A61F2/1675 , A61F2/1629 , A61F2/1648 , A61F2/1678 , A61F2002/1683 , A61F2250/0021 , A61F2250/0025
摘要： An injector for inserting an intraocular lens into an eye includes a lumen. The lumen can include a terminal portion at a distal end and a proximal portion juxtaposed with the terminal portion. An injector plunger can be disposed within the lumen for generating a driving force on the intraocular lens. The injector can include a lens frictional force that has a first value when the lens is at a first location within the proximal portion and a second value when the lens is at a second location within the terminal portion. The first value can be smaller than the second value. In some embodiments, the lens frictional force increases abruptly from the first value to the second value as the lens approaches the distal end of the lumen.
摘要翻译：用于将眼内透镜插入眼睛的注射器包括管腔。内腔可包括位于远端的末端部分和与终端部分并置的近端部分。注射器柱塞可以设置在内腔内，以在眼内透镜上产生驱动力。注射器可以包括当透镜位于近端部分内的第一位置时具有第一值的透镜摩擦力，以及当透镜位于端子部分内的第二位置时的第二值。第一个值可以小于第二个值。在一些实施例中，当镜片接近管腔的远端时，透镜摩擦力从第一值突然增加到第二值。

5. 发明申请

US20130245756A1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS 有权
标题翻译：内窥镜系统的共聚物
公开(公告)号：US20130245756A1
公开(公告)日：2013-09-19
申请号：US13868727
申请日：2013-04-23
申请人： VISIOGEN, INC.
发明人： Xiugao Liao
IPC分类号： A61F2/16
CPC分类号： A61F2/16 , A61F2/1648 , A61F2002/1681 , C08F220/18 , C08F220/36 , C08F230/08
摘要： Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.
摘要翻译：一些实施方案提供了一种共聚物，其包含：丙烯酸酯重复单元和任选取代的乙烯基芳基重复单元，其中至少一个重复单元的一部分包含乙烯基二烷基甲硅烷氧基侧基。共聚物可用作眼内透镜的柔软的丙烯酸类触觉剂。一些实施例进一步涉及具有疏水性柔性丙烯酸光学元件和硅树脂触觉元件的眼内透镜，例如具有疏水柔软的丙烯酸前和后视觉体和硅树脂触觉的双光学调节透镜。相关的共聚合复合材料以及眼内透镜的另外的实施方案也在本文中描述。

6. 发明专利

CA2783649C DUAL OPTIC ACCOMMODATING INTRAOCULAR LENS SYSTEM 未知
公开(公告)号：CA2783649C
公开(公告)日：2015-07-21
申请号：CA2783649
申请日：2002-01-25
申请人： VISIOGEN INC
发明人： ZADNO-AZIZI GHOLAM-REZA , ROGERS ERICA J , NGUYEN TUAN ANH , TING ALBERT C , PORTNEY VALDEMAR , PHAM HAI-MINH
IPC分类号： A61F2/16 , B29D11/02
摘要： An intraocular lens having first and second viewing elements can be prepared for implantation according to methods for displacing the viewing elements relative to each other as disclosed herein. In some embodiments, the anterior viewing element connected to an anterior translation member and the posterior viewing element connected to a posterior translation member. The anterior translation member and the posterior translation member connected at an apex. The anterior translation member capable of moving an optic of the anterior viewing element relative to an optic of the posterior viewing along an optical axis of the lens such that the anterior optic and the posterior optic are positioned further apart when the anterior optic is in the accommodated position than when the anterior optic is in the unaccommodated position.

7. 发明专利

AU2009223556B2 Method and injector for inserting an intraocular lens 未知
公开(公告)号：AU2009223556B2
公开(公告)日：2014-07-17
申请号：AU2009223556
申请日：2009-03-06
申请人： VISIOGEN INC
发明人： NGUYEN PHU H , TSAI GEORGE , EVANS SCOTT , NGUYEN TUAN ANH
IPC分类号： A61F2/16
摘要： An injector (900) for inserting an intraocular lens (930, 980) into an eye includes a lumen (910). The lumen (910, 960) can include a terminal portion (912, 962) at a distal end (916, 966) and a proximal portion (914, 964) juxtaposed with the terminal portion (912, 962). An injector plunger (920, 970) can be disposed within the lumen (910, 960) for generating a driving force (944, 994) on the intraocular lens (930, 980). The injector (900) can include a lens frictional force (942) that has a first value when the lens (930, 980) is at a first location (Ll) within the proximal portion (914, 964) and a second value when the lens (930, 980) is a,t a second location (L2) within the terminal portion (912, 962). The first value can be smaller than the second value.

8. 发明专利

CA2493673C METHOD OF PREPARING AN INTRAOCULAR LENS FOR IMPLANTATION 未知
公开(公告)号：CA2493673C
公开(公告)日：2012-04-10
申请号：CA2493673
申请日：2003-07-24
申请人： VISIOGEN INC
发明人： ZADNO-AZIZI GHOLAM-REZA , TING ALBERT C , NGUYEN TUAN ANH , PORTNEY VALDEMAR , PHAM HAI-MINH
IPC分类号： A61F2/16 , A61L27/00
摘要： An accommodating intraocular lens, comprising: an anterior portion having an anterior viewing element; a posterior portion having a posterior viewing element, the viewing elements being positioned to move relative to each other in response to force on the intraocular lens, so as to alter the refractive power of the lens; wherein the anterior and posterior portions comprise a single piece of material. A method of making such a lens is also provided.

9. 发明申请

WO2010093823A2 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS 审中-公开
标题翻译：内窥镜系统的共聚物
公开(公告)号：WO2010093823A2
公开(公告)日：2010-08-19
申请号：PCT/US2010023946
申请日：2010-02-11
申请人： VISIOGEN INC , LIAO XIUGAO
发明人： LIAO XIUGAO
IPC分类号： C08F220/18
CPC分类号： A61F2/16 , A61F2/1648 , A61F2002/1681 , C08F220/18 , C08F220/36 , C08F230/08
摘要： Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.
摘要翻译：一些实施方案提供了一种共聚物，其包含：丙烯酸酯重复单元和任选取代的乙烯基芳基重复单元，其中至少一个重复单元的一部分包含乙烯基二烷基甲硅烷氧基侧基。共聚物可用作眼内透镜的柔软的丙烯酸类触觉剂。一些实施例进一步涉及具有疏水性柔性丙烯酸光学元件和硅树脂触觉元件的眼内透镜，例如具有疏水柔软的丙烯酸前后视觉体和硅树脂触觉的双光学调节透镜。相关的共聚合复合材料以及眼内透镜的另外的实施方案也在本文中描述。

10. 发明专利

CA2849167C INTRAOCULAR LENSES AND METHODS OF PREPARING OR MAKING SAME 未知
公开(公告)号：CA2849167C
公开(公告)日：2016-06-28
申请号：CA2849167
申请日：2003-07-24
申请人： VISIOGEN INC
发明人： ZADNO-AZIZI GHOLAM-REZA , TING ALBERT C , NGUYEN TUAN ANH , PORTNEY VALDEMAR , PHAM HAI-MINH
IPC分类号： A61F2/16 , A61L27/00
摘要： A method of preparing an accommodating intraocular lens having an optical axis for subsequent implantation involves providing an intraocular lens having first and second viewing elements interconnected by plural members. At least a portion of the members are disposed from the optical axis by a distance greater than a periphery of at least one of the viewing elements. The distance is measured orthogonal to the optical axis. The method further involves drawing the members inwardly toward the optical axis by relatively rotating the first and second viewing elements, and increasing the separation between the viewing elements along the optical axis while drawing the members inwardly.

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