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1. 发明申请

WO2011084490A1 METHOD AND APPARATUS FOR STABILIZING, STRAIGHTENING, OR EXPANDING THE WALL OF A LUMEN OR CAVITY 审中-公开
标题翻译：用于稳定，连接或扩展壁或室的方法和装置
公开(公告)号：WO2011084490A1
公开(公告)日：2011-07-14
申请号：PCT/US2010/060521
申请日：2010-12-15
申请人： CORNELL UNIVERSITY , MILSOM, Jeffrey , RIINA, Howard , CORNHILL, J., Frederick , DICKINSON, Edward, L. , STROHL, Clair, L. , MAHONEY, James , COPPOLA, Pat
发明人： MILSOM, Jeffrey , RIINA, Howard , CORNHILL, J., Frederick , DICKINSON, Edward, L. , STROHL, Clair, L. , MAHONEY, James , COPPOLA, Pat
IPC分类号： A61B1/04 , A61B1/00
CPC分类号： A61B1/00082 , A61B1/00135 , A61B1/31
摘要： The present invention comprises the provision and use of a novel endoscopic device which is capable of stabilizing, straightening, expanding and/or flattening the side wall of a body lumen and/or body cavity so as to better present the side wall tissue for examination and/or treatment during an endoscopic procedure. The present invention also comprises the provision and use of a novel endoscopic device capable of steadying and/or stabilizing the distal tips and/or working ends of instruments inserted into a body lumen and/or body cavity, whereby to facilitate the use of those instruments.
摘要翻译：本发明包括提供和使用能够使体腔和/或体腔的侧壁稳定，矫直，膨胀和/或变平的新型内窥镜装置，以便更好地呈现侧壁组织进行检查， /或内窥镜手术中的治疗。本发明还包括提供和使用能够稳定和/或稳定插入体腔和/或体腔中的器械的远端和/或工作端的新型内窥镜装置，从而便于使用这些器械。

2. 发明申请

WO2009152257A1 METHOD AND APPARATUS FOR REPAIRING VACULAR ABNORMALTIES AND/OR OTHER BODY LUMEN ABNORMALTIES USING AN ENDOLUMINAL APPROACH AND A FLOWABLE FORMING MATERIAL 审中-公开
标题翻译：使用内膜方法和流动性成形材料修复眼睛不适和/或其他身体不适的方法和装置
公开(公告)号：WO2009152257A1
公开(公告)日：2009-12-17
申请号：PCT/US2009/046929
申请日：2009-06-10
申请人： CORNELL UNIVERSITY , RIINA, Howard , MILSOM, Jeffrey , CORNHILL, J., Fredrick , ANDREWS, Robert, R. , STROHL, Clair, L. , DICKINSON, Edward, L.
发明人： RIINA, Howard , MILSOM, Jeffrey , CORNHILL, J., Fredrick , ANDREWS, Robert, R. , STROHL, Clair, L. , DICKINSON, Edward, L.
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61F2/945 , A61F2002/30583 , A61F2002/823 , A61F2210/0085 , A61M25/1011 , A61M29/02 , A61M2025/1052
摘要： A method for repairing an abnormality in the wall of a body lumen, the method comprising: isolating the abnormality in the wall of the body lumen from flow in the body lumen; positioning flowable forming material adjacent to the abnormality in the wall of the body lumen; and transforming the flowable forming material into a substantially stationary state so as to repair the abnormality in the wall of the body lumen. Apparatus for repairing an abnormality in the wall of a body lumen, the apparatus comprising: a supply of flowable forming material; zone isolation apparatus for isolating the abnormality in the wall of the body lumen from flow in the body lumen; and positioning apparatus for positioning the flowable forming material adjacent to the abnormality in the wall of the body lumen so as to repair the abnormality in the wall of the body lumen.
摘要翻译：一种用于修复体腔壁的异常的方法，所述方法包括：将体腔内的异常与体腔内的流动隔离; 将可流动的成形材料定位成与体腔壁的异常相邻; 并将可流动的成形材料转化成基本静止的状态，以便修复体腔的壁中的异常。用于修复体腔壁的异常的装置，所述装置包括：供应可流动的成形材料; 区隔离装置，用于将体腔内壁的异常与体腔内的流动隔离; 以及定位装置，用于将可流动的形成材料定位在体腔的壁中与异常相邻，以便修复体腔壁的异常。

3. 发明申请

WO2010021779A1 METHOD AND APPARATUS FOR ACCESSING THE WALL OF A VASCULAR STRUCTURE OR OTHER BODY LUMEN WHILE SIMULTANEOUSLY PROVIDING ZONE ISOLATION AND FLUID BYPASS CAPABILITY 审中-公开
标题翻译：用于在同时提供区域隔离和流体旁路能力的情况下接入血管结构或其他体液的壁的方法和装置
公开(公告)号：WO2010021779A1
公开(公告)日：2010-02-25
申请号：PCT/US2009/046840
申请日：2009-06-10
申请人： CORNELL UNIVERSITY , RIINA, Howard , MILSOM, Jeffrey , CORNHILL, J., Fredrick , ANDREWS, Robert , STROHL, Clair, L. , DICKINSON, Edward, L.
发明人： RIINA, Howard , MILSOM, Jeffrey , CORNHILL, J., Fredrick , ANDREWS, Robert , STROHL, Clair, L. , DICKINSON, Edward, L.
IPC分类号： A61M29/00
CPC分类号： A61M25/1011 , A61B17/12022 , A61B17/12036 , A61B17/12045 , A61B17/12113 , A61B17/12136 , A61B2017/1205 , A61B2017/12127 , A61M29/02 , A61M2025/1052 , A61M2025/1095 , A61M2205/0266
摘要： Apparatus and method for accessing the wall of a body lumen while simultaneously providing zone isolation and fluid bypass capability, the apparatus comprising: an erectable proximal isolation barrier capable of making a sealing engagement with the wall of the body lumen; an erectable distal isolation barrier capable of making a sealing engagement with the wall of the body lumen; a bypass channel secured to, and extending between, the proximal isolation barrier and the distal isolation barrier, the bypass channel comprising a lumen communicating with the region proximal to the proximal isolation barrier and with the region distal to the distal isolation barrier; and a working catheter passing through the proximal isolation barrier and terminating short of the distal isolation barrier, the working catheter providing a central lumen for providing access to the wall of the body lumen between the proximal isolation barrier and the distal isolation barrier.
摘要翻译：用于在同时提供区域隔离和流体旁路能力的同时提供区域隔离和流体旁路能力的情况下访问体腔的壁的装置和方法，该装置包括：能够与体腔的壁进行密封接合的可直立的近侧隔离屏障; 能够与体腔的壁进行密封接合的可直立的远端隔离屏障; 所述旁路通道固定到所述近侧隔离屏障和所述远端隔离屏障之间并在其之间延伸，所述旁路通道包括与所述近侧隔离屏障近侧的区域连通并且远离所述远端隔离屏障的区域; 所述工作导管通过所述近侧隔离屏障并且终止于所述远侧隔离屏障之外，所述工作导管提供中心腔，用于提供对所述近端隔离屏障和所述远端隔离屏障之间的所述体腔壁的通路。

4. 发明申请

WO1990002514A1 METHOD AND APPARATUS FOR CATHETER LOCATION DETERMINATION 审中-公开
标题翻译：用于导管位置确定的方法和装置
公开(公告)号：WO1990002514A1
公开(公告)日：1990-03-22
申请号：PCT/US1989003989
申请日：1989-09-13
申请人： PHARMACIA DELTEC INC. , STROHL, Clair, L., Jr. , FERRAGAMO, Michael, C. , KAY, Donald, A. , SHAPIRO, Alan, R. , WHIPPLE, Gary, R.
发明人： PHARMACIA DELTEC INC.
IPC分类号： A61B05/06
CPC分类号： A61B5/06 , A61B5/062
摘要： A method and apparatus (10) for determining accurately the location of the tip (14) of a catheter (16) inside biological tissue is disclosed including a locator (34) having a coil (38) wound axially on a core (36) and a detector (12) in the form of a coil (28) wound on a core (24) removably positionable within catheter (16) adjacent the tip (14). A controller (20) generates AC current to coil (38) to produce an electromagnetic field and compares it with the output voltage developed in coil (28) when the locator (34) comes within close physical proximity to detector (12). Locator (34) includes an amber LED indicator (42) which is energized when the locator (34) is behind the detector (12) and the monitored output voltage is in phase with the generated alternating current and includes a red LED indicator (44) which is energized when the locator (34) is beyond the detector (12) and the monitored output voltage is 180° out of phase with the generated alternating current. The controller (20) includes a beeper (48) which provides an audible indicator when energization changes between the indicators (42, 44).
摘要翻译：公开了一种用于准确地确定生物组织内的导管（16）的尖端（14）的位置的方法和装置（10），包括定位器（34），该定位器具有轴向地卷绕在芯部（36）上的线圈（38）卷绕在芯子（24）上的线圈（28）形式的检测器（12），其可拆卸地定位在邻近尖端（14）的导管（16）内。控制器（20）产生交流电流到线圈（38）以产生电磁场，并且当定位器（34）进入与物体接近检测器（12）时，与线圈（28）中产生的输出电压进行比较。定位器（34）包括琥珀色LED指示器（42），当定位器（34）位于检测器（12）后面时被激励，并且所监视的输出电压与产生的交流电流同相并且包括红色LED指示器（44）当定位器（34）超出检测器（12）并且所监视的输出电压与产生的交流电流相差180°时，其被通电。控制器（20）包括蜂鸣器（48），当在指示器（42,44）之间通电时，提供可听指示器。

5. 发明申请

WO2010085344A1 METHOD AND APPARATUS FOR RESTRICTING FLOW THROUGH THE WALL OF A LUMEN 审中-公开
标题翻译：通过壁面限制流动的方法和装置
公开(公告)号：WO2010085344A1
公开(公告)日：2010-07-29
申请号：PCT/US2010/000159
申请日：2010-01-22
申请人： CORNELL UNIVERSITY , RIINA, Howard , ANDREWS, Robert , STROHL, Clair , MILSOM, Jeffrey , CORNHILL, J., Fredrick , SMITH, Kevin, Thomas , LAMPHERE, David, G. , NGUYEN, Tuan, Anh
发明人： RIINA, Howard , ANDREWS, Robert , STROHL, Clair , MILSOM, Jeffrey , CORNHILL, J., Fredrick , SMITH, Kevin, Thomas , LAMPHERE, David, G. , NGUYEN, Tuan, Anh
IPC分类号： A61F2/82
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/12118 , A61B17/12131 , A61B17/1214 , A61B17/12172 , A61B17/12177 , A61B17/1219 , A61B2017/00867 , A61B2017/00871 , A61B2017/12054 , A61F2/82 , A61F2/86 , A61F2/91 , A61F2/95 , A61F2002/30242 , A61F2002/823 , A61F2002/9505 , A61F2230/005 , A61F2230/0071 , A61F2230/0091 , A61F2230/0095
摘要： An expandable substantially spherical structure for deployment in a blood vessel or other body lumen, comprising: an open frame formed out of a closed loop of filament and configured to assume (i) a collapsed configuration in the form of a substantially two-dimensional elongated loop structure so as to facilitate insertion into the blood vessel or other body lumen, and (ii) an expanded configuration in the form of a three-dimensional substantially spherical structure so as to facilitate retention at a site in the blood vessel or other body lumen; and a flow-restricting face carried by the open frame; wherein the open frame is configured so as to permit substantially normal flow therethrough when the open frame is in its expanded configuration, and further wherein the flow-restricting face is configured so as to restrict flow therethrough.
摘要翻译：一种用于展开在血管或其他体腔中的可扩张的基本上为球形的结构，包括：由细丝的闭合环形成的开放框架，并且构造成采取以下步骤：（i）呈基本上二维细长环的形式的折叠构型结构，以便于插入到血管或其他体腔中，以及（ii）三维大致球形结构形式的扩张构型，以便于保持在血管或其他体腔中的部位; 以及由开放框架承载的流动限制面; 其中，所述开放框架构造成当所述开放框架处于其膨胀构造时允许基本上正常的流过其中，并且进一步其中所述流动限制面被构造成限制流过其中。

6. 发明申请

WO2009076515A1 METHOD AND APPARATUS FOR SEALING AN OPENING IN THE SIDE WALL OF A BODY LUMEN 审中-公开
标题翻译：用于在身体壁的侧壁上打开的方法和装置
公开(公告)号：WO2009076515A1
公开(公告)日：2009-06-18
申请号：PCT/US2008/086393
申请日：2008-12-11
申请人： CORNELL UNIVERSITY , RIINA, Howard , ANDREWS, Robert , STROHL, Clair , MILSOM, Jeffrey , CORNHILL, J., Fredrick , SMITH, Kevin, Thomas , LAMPHERE, David, G. , NGUYEN, Tuan, Anh
发明人： RIINA, Howard , ANDREWS, Robert , STROHL, Clair , MILSOM, Jeffrey , CORNHILL, J., Fredrick , SMITH, Kevin, Thomas , LAMPHERE, David, G. , NGUYEN, Tuan, Anh
IPC分类号： A61F2/94
CPC分类号： A61F2/86 , A61B17/12022 , A61B17/12113 , A61B17/12118 , A61B17/12131 , A61B17/12172 , A61B17/1219 , A61B2017/00867 , A61B2017/12054 , A61F2/82 , A61F2/91 , A61F2/95 , A61F2002/30242 , A61F2002/823 , A61F2230/005 , A61F2230/0071 , A61F2230/0091 , A61F2230/0095
摘要： An expandable spherical structure for deployment in a blood vessel or other body lumen, comprising: an open frame configured to assume a collapsed configuration and an expanded configuration; and a closed face carried by the open frame; wherein the open frame is configured so as to permit substantially normal flow therethrough when the open frame is in its expanded configuration, and further wherein the closed face is configured so as to obstruct flow therethrough.
摘要翻译：一种用于部署在血管或其他体腔中的可扩张球形结构，包括：开放框架，其构造为呈现收缩构型和扩张构型; 和由开放框架承载的封闭面; 其中所述开放框架构造成当所述开放框架处于其膨胀构型时允许基本上正常的流过其中，并且其中所述闭合面构造成妨碍流过其中。

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